KEGG   Homo sapiens (human): 91662
Entry
91662             CDS       T01001                                 
Symbol
NLRP12, CLR19.3, FCAS2, NALP12, PAN6, PYPAF7, RNO, RNO2
Name
(RefSeq) NLR family pyrin domain containing 12
  KO
K20865  NACHT, LRR and PYD domains-containing protein 12
Organism
hsa  Homo sapiens (human)
Pathway
hsa04621  NOD-like receptor signaling pathway
Network
nt06521  NLR signaling
  Element
N01569  NALP12 inflammasome signaling pathway
Disease
H02159  Familial cold autoinflammatory syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    91662 (NLRP12)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors [BR:hsa04054]
    91662 (NLRP12)
Pattern recognition receptors [BR:hsa04054]
 Cytoplasmic pattern recognition receptors
  NOD-like receptors
   91662 (NLRP12)
SSDB
Motif
Pfam: NACHT NLRC4_HD2 PYRIN LRR_6 NOD2_WH FISNA LRR_4 nSTAND3 NB-ARC AAA_16 AAA_25
Other DBs
NCBI-GeneID: 91662
NCBI-ProteinID: NP_653288
OMIM: 609648
HGNC: 22938
Ensembl: ENSG00000142405
UniProt: P59046
Structure
Position
19:complement(53793584..53824403)
AA seq 1061 aa
MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGSMEKAGPLEMAQLL
ITHFGPEEAWRLALSTFERINRKDLWERGQREDLVRDTPPGGPSSLGNQSTCLLEVSLVT
PRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTG
RGHARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGAAGIGKSMLAHKVMLDWADGKLF
QGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQELIRVPERLLFIIDGFDELK
PSFHDPQGPWCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHPRHV
EILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEG
GGLLRQTSRTTTAVYMLYLLSLMQPKPGAPRLQPPPNQRGLCSLAADGLWNQKILFEEQD
LRKHGLDGEDVSAFLNMNIFQKDINCERYYSFIHLSFQEFFAAMYYILDEGEGGAGPDQD
VTRLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQ
SDGSTLQQGSLEFFSCLYEIQEEEFIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSA
QVLHLYGATYSADGEDRARCSAGAHTLLVQLPERTVLLDAYSEHLAAALCTNPNLIELSL
YRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISSSACEDLSAALIANKNLTRMDLSGN
GVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMASVLGTNPHLVELDLTGNALE
DLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLG
VLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVVLQANHNLRELDLSFNDLGDWGLWL
LAEGLQHPACRLQKLWLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCK
RLSHPGCKLRVLWLFGMDLNKMTHSRLAALRVTKPYLDIGC
NT seq 3186 nt   +upstreamnt  +downstreamnt
atgctacgaaccgcaggcagggacggcctctgtcgcctgtccacctacttggaagaactc
gaggctgtggaactgaagaagttcaagttatacctggggaccgcgacagagctgggagaa
ggcaagatcccctggggaagcatggagaaggccggtcccctggaaatggcccagctgctc
atcacccacttcgggccagaggaggcctggaggttggctctcagcacctttgagcggata
aacaggaaggacctgtgggagagaggacagagagaggacctggtgagggataccccacct
ggtggcccgtcctcacttgggaaccagtcaacatgccttctggaagtctctcttgtcact
ccaagaaaagatccccaggaaacctacagggactatgtccgcaggaaattccggctcatg
gaagaccgcaatgcgcgcctaggggaatgtgtcaacctcagccaccggtacacccggctc
ctgctggtgaaggagcactcaaaccccatgcaggtccagcagcagcttctggacacaggc
cggggacacgcgaggaccgtgggacaccaggctagccccatcaagatagagaccctcttt
gagccagacgaggagcgccccgagccaccgcgcaccgtggtcatgcaaggcgcggcaggg
ataggcaagtccatgctggcacacaaggtgatgctggactgggcggacgggaagctcttc
caaggcagatttgattatctcttctacatcaactgcagggagatgaaccagagtgccacg
gaatgcagcatgcaagacctcatcttcagctgctggcctgagcccagcgcgcctctccag
gagctcatccgagttcccgagcgcctccttttcatcatcgacggcttcgatgagctcaag
ccttctttccacgatcctcagggaccctggtgcctctgctgggaggagaaacggcccacg
gagctgcttcttaacagcttaattcggaagaagctgctccctgagctatctttgctcatc
accacacggcccacggctttggagaagctccaccgtctgctggagcaccccaggcatgtg
gagatcctgggcttctctgaggcagaaaggaaggaatacttctacaagtatttccacaat
gcagagcaggcgggccaagtcttcaattacgtgagggacaacgagcctctcttcaccatg
tgcttcgtccccctggtgtgctgggtggtgtgtacctgcctccagcagcagctggagggt
ggggggctgttgagacagacgtccaggaccaccactgcagtgtacatgctctacctgctg
agtctgatgcaacccaagccgggggccccgcgcctccagcccccacccaaccagagaggg
ttgtgctccttggcggcagatgggctctggaatcagaaaatcctatttgaggagcaggac
ctccggaagcacggcctagacggggaagacgtctctgccttcctcaacatgaacatcttc
cagaaggacatcaactgtgagaggtactacagcttcatccacttgagtttccaggaattc
tttgcagctatgtactatatcctggacgagggggagggcggggcaggcccagaccaggac
gtgaccaggctgttgaccgagtacgcgttttctgaaaggagcttcctggcactcaccagc
cgcttcctgtttggactcctgaacgaggagaccaggagccacctggagaagagtctctgc
tggaaggtctcgccgcacatcaagatggacctgttgcagtggatccaaagcaaagctcag
agcgacggctccaccctgcagcagggctccttggagttcttcagctgcttgtacgagatc
caggaggaggagtttatccagcaggccctgagccacttccaggtgatcgtggtcagcaac
attgcctccaagatggagcacatggtctcctcgttctgtctgaagcgctgcaggagcgcc
caggtgctgcacttgtatggcgccacctacagcgcggacggggaagaccgcgcgaggtgc
tccgcaggagcgcacacgctgttggtgcagctaccagagaggaccgttctgctggacgcc
tacagtgaacatctggcagcggccctgtgcaccaatccaaacctgatagagctgtctctg
taccgaaatgccctgggcagccggggggtgaagctgctctgtcaaggactcagacacccc
aactgcaaacttcagaacctgaggctgaagaggtgccgcatctccagctcagcctgcgag
gacctctctgcagctctcatagccaataagaatttgacaaggatggatctcagtggcaac
ggcgttggattcccaggcatgatgctgctttgcgagggcctgcggcatccccagtgcagg
ctgcagatgattcagttgaggaagtgtcagctggagtccggggcttgtcaggagatggct
tctgtgctcggcaccaacccacatctggttgagttggacctgacaggaaatgcactggag
gatttgggcctgaggttactatgccagggactgaggcacccagtctgcagactacggact
ttgtggctgaagatctgccgcctcactgctgctgcctgtgacgagctggcctcaactctc
agtgtgaaccagagcctgagagagctggacctgagcctgaatgagctgggggacctcggg
gtgctgctgctgtgtgagggcctcaggcatcccacgtgcaagctccagaccctgcggttg
ggcatctgccggctgggctctgccgcctgtgagggtctttctgtggtgctccaggccaac
cacaacctccgggagctggacttgagtttcaacgacctgggagactggggcctgtggttg
ctggctgaggggctgcaacatcccgcctgcagactccagaaactgtggctggatagctgt
ggcctcacagccaaggcttgtgagaatctttacttcaccctggggatcaaccagaccttg
accgacctttacctgaccaacaacgccctaggggacacaggtgtccgactgctttgcaag
cggctgagccatcctggctgcaaactccgagtcctctggttatttgggatggacctgaat
aaaatgacccacagtaggttggcagcgcttcgagtaacaaaaccttatttggacattggc
tgctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (29)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (27)   
DNA sequence (50)   
   RefSeq(nuc) (28)   
   GenBank (11)   
   EMBL (11)   
3D Structure (3)   
   PDB (3)   
Protein domain (11)   
   Pfam (11)   
All databases (134)   

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