Entry |
|
Gene name |
CD247, CD3-ZETA, CD3H, CD3Q, CD3Z, IMD25, T3Z, TCRZ
|
Definition |
|
KO |
K06453 | CD3Z antigen, zeta polypeptide |
|
Organism |
|
Pathway |
hsa04650 | Natural killer cell mediated cytotoxicity |
hsa04658 | Th1 and Th2 cell differentiation |
hsa04660 | T cell receptor signaling pathway |
hsa05170 | Human immunodeficiency virus 1 infection |
hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer |
|
Disease |
H00091 | T-B+Severe combined immunodeficiency |
|
Brite |
KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
919 (CD247)
04660 T cell receptor signaling pathway
919 (CD247)
04658 Th1 and Th2 cell differentiation
919 (CD247)
04659 Th17 cell differentiation
919 (CD247)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
919 (CD247)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
919 (CD247)
05169 Epstein-Barr virus infection
919 (CD247)
09174 Infectious disease: parasitic
05142 Chagas disease
919 (CD247)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:hsa04147]
919 (CD247)
04090 CD molecules [BR:hsa04090]
919 (CD247)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
919 (CD247)
CD molecules [BR:hsa04090]
Proteins
919 (CD247)
|
SSDB |
|
Motif |
|
Other DBs |
|
Structure |
PDB: |
Position |
1q24.2
|
AA seq |
164 aa
MKWKALFTAAILQAQLPITEAQSFGLLDPKLCYLLDGILFIYGVILTALFLRVKFSRSAD
APAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKPQRRKNPQEGLYNELQKDKMA
EAYSEIGMKGERRRGKGHDGLYQGLSTATKDTYDALHMQALPPR |
NT seq |
495 nt +upstreamnt +downstreamnt
atgaagtggaaggcgcttttcaccgcggccatcctgcaggcacagttgccgattacagag
gcacagagctttggcctgctggatcccaaactctgctacctgctggatggaatcctcttc
atctatggtgtcattctcactgccttgttcctgagagtgaagttcagcaggagcgcagac
gcccccgcgtaccagcagggccagaaccagctctataacgagctcaatctaggacgaaga
gaggagtacgatgttttggacaagagacgtggccgggaccctgagatggggggaaagccg
cagagaaggaagaaccctcaggaaggcctgtacaatgaactgcagaaagataagatggcg
gaggcctacagtgagattgggatgaaaggcgagcgccggaggggcaaggggcacgatggc
ctttaccagggtctcagtacagccaccaaggacacctacgacgcccttcacatgcaggcc
ctgccccctcgctaa |