| Entry |
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| Gene name |
MAPKAPK2, MAPKAP-K2, MK-2, MK2
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| Definition |
(RefSeq) mitogen-activated protein kinase-activated protein kinase 2
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| KO |
| K04443 | mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1] |
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| Organism |
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| Pathway |
| hsa04625 | C-type lectin receptor signaling pathway |
| hsa05167 | Kaposi sarcoma-associated herpesvirus infection |
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| Network |
nt06110 MAPK signaling (virus) nt06164 Kaposi sarcoma-associated herpesvirus (KSHV) nt06211 Other MAPK signaling |
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| Element |
| N00186 | IL1-IL1R-p38 signaling pathway |
| N00187 | KSHV Kaposin B to p38 signaling pathway |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
9261 (MAPKAPK2)
04370 VEGF signaling pathway
9261 (MAPKAPK2)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
9261 (MAPKAPK2)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
9261 (MAPKAPK2)
09156 Nervous system
04722 Neurotrophin signaling pathway
9261 (MAPKAPK2)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
9261 (MAPKAPK2)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
9261 (MAPKAPK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
9261 (MAPKAPK2)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
9261 (MAPKAPK2)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: CAMK group
MAPKAPK family [OT]
9261 (MAPKAPK2)
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
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| Structure |
PDB: |
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| Position |
1q32.1
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| AA seq |
400 aa  
MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH |
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| NT seq |
1203 nt  +upstreamnt +downstreamnt
atgctgtccaactcccagggccagagcccgccggtgccgttccccgccccggccccgccg
ccgcagccccccacccctgccctgccgcaccccccggcgcagccgccgccgccgcccccg
cagcagttcccgcagttccacgtcaagtccggcctgcagatcaagaagaacgccatcatc
gatgactacaaggtcaccagccaggtcctggggctgggcatcaacggcaaagttttgcag
atcttcaacaagaggacccaggagaaattcgccctcaaaatgcttcaggactgccccaag
gcccgcagggaggtggagctgcactggcgggcctcccagtgcccgcacatcgtacggatc
gtggatgtgtacgagaatctgtacgcagggaggaagtgcctgctgattgtcatggaatgt
ttggacggtggagaactctttagccgaatccaggatcgaggagaccaggcattcacagaa
agagaagcatccgaaatcatgaagagcatcggtgaggccatccagtatctgcattcaatc
aacattgcccatcgggatgtcaagcctgagaatctcttatacacctccaaaaggcccaac
gccatcctgaaactcactgactttggctttgccaaggaaaccaccagccacaactctttg
accactccttgttatacaccgtactatgtggctccagaagtgctgggtccagagaagtat
gacaagtcctgtgacatgtggtccctgggtgtcatcatgtacatcctgctgtgtgggtat
ccccccttctactccaaccacggccttgccatctctccgggcatgaagactcgcatccga
atgggccagtatgaatttcccaacccagaatggtcagaagtatcagaggaagtgaagatg
ctcattcggaatctgctgaaaacagagcccacccagagaatgaccatcaccgagtttatg
aaccacccttggatcatgcaatcaacaaaggtccctcaaaccccactgcacaccagccgg
gtcctgaaggaggacaaggagcggtgggaggatgtcaaggaggagatgaccagtgccttg
gccacaatgcgcgttgactacgagcagatcaagataaaaaagattgaagatgcatccaac
cctctgctgctgaagaggcggaagaaagctcgggccctggaggctgcggctctggcccac
tga |
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