KEGG   Homo sapiens (human): 9361
Entry
9361              CDS       T01001                                 
Symbol
LONP1, CODASS, LON, LONP, LonHS, PIM1, PRSS15, hLON
Name
(RefSeq) lon protease homolog, mitochondrial isoform 1 precursor
  KO
K08675  ATP-dependent Lon protease [EC:3.4.21.53]
Organism
hsa  Homo sapiens (human)
Disease
H01824  CODAS syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    9361 (LONP1)
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:hsa03029]
    9361 (LONP1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.53  endopeptidase La
     9361 (LONP1)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S16: lon protease family
   9361 (LONP1)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    9361 (LONP1)
SSDB
Motif
Pfam: Lon_C LON_substr_bdg AAA Lon_lid AAA_5 AAA_2 RuvB_N ChlI AAA_PrkA AAA_22 AAA_16 AAA_14 ATPase_2 NPHP3_N bpMoxR RNA_helicase nSTAND3 LXG AAA_17 NB-ARC NTPase_1 AAA_18 Parvo_NS1 Viral_helicase1 RsgA_GTPase AAA_28 TsaE NACHT AAA_7 AAA_19 ABC_tran AAA_3 AAA_24
Other DBs
NCBI-GeneID: 9361
NCBI-ProteinID: NP_004784
OMIM: 605490
HGNC: 9479
Ensembl: ENSP00000353826.2
UniProt: P36776
Structure
Position
19:complement(5691834..5720452)
AA seq 959 aa
MAASTGYVRLWGAARCWVLRRPMLAAAGGRVPTAAGAWLLRGQRTCDASPPWALWGRGPA
IGGQWRGFWEASSRGGGAFSGGEDASEGGAEEGAGGAGGSAGAGEGPVITALTPMTIPDV
FPHLPLIAITRNPVFPRFIKIIEVKNKKLVELLRRKVRLAQPYVGVFLKRDDSNESDVVE
SLDEIYHTGTFAQIHEMQDLGDKLRMIVMGHRRVHISRQLEVEPEEPEAENKHKPRRKSK
RGKKEAEDELSARHPAELAMEPTPELPAEVLMVEVENVVHEDFQVTEEVKALTAEIVKTI
RDIIALNPLYRESVLQMMQAGQRVVDNPIYLSDMGAALTGAESHELQDVLEETNIPKRLY
KALSLLKKEFELSKLQQRLGREVEEKIKQTHRKYLLQEQLKIIKKELGLEKDDKDAIEEK
FRERLKELVVPKHVMDVVDEELSKLGLLDNHSSEFNVTRNYLDWLTSIPWGKYSNENLDL
ARAQAVLEEDHYGMEDVKKRILEFIAVSQLRGSTQGKILCFYGPPGVGKTSIARSIARAL
NREYFRFSVGGMTDVAEIKGHRRTYVGAMPGKIIQCLKKTKTENPLILIDEVDKIGRGYQ
GDPSSALLELLDPEQNANFLDHYLDVPVDLSKVLFICTANVTDTIPEPLRDRMEMINVSG
YVAQEKLAIAERYLVPQARALCGLDESKAKLSSDVLTLLIKQYCRESGVRNLQKQVEKVL
RKSAYKIVSGEAESVEVTPENLQDFVGKPVFTVERMYDVTPPGVVMGLAWTAMGGSTLFV
ETSLRRPQDKDAKGDKDGSLEVTGQLGEVMKESARIAYTFARAFLMQHAPANDYLVTSHI
HLHVPEGATPKDGPSAGCTIVTALLSLAMGRPVRQNLAMTGEVSLTGKILPVGGIKEKTI
AAKRAGVTCIVLPAENKKDFYDLAAFITEGLEVHFVEHYREIFDIAFPDEQAEALAVER
NT seq 2880 nt   +upstreamnt  +downstreamnt
atggcggcgagcactggctacgtgcgactgtggggagcggcgcggtgctgggtgctgcgg
cggccgatgctggccgccgccggggggcgggttcccactgcagcaggagcgtggttgctc
cgaggccagcggacctgcgacgcctctcctccttgggcactgtggggccgaggcccggca
attgggggccaatggcgggggttttgggaagcgagcagccgcggcggaggcgcattctcg
gggggcgaggacgcctccgagggcggcgcggaggaaggagccggcggcgcggggggcagc
gcgggcgccggggaaggcccggtcataacggcgctcacgcccatgacgatccccgatgtg
tttccgcacctgccgctcatcgccatcacccgcaacccggtgttcccgcgctttatcaag
attatcgaggttaaaaataagaagttggttgagctgctgagaaggaaagttcgtctcgcc
cagccttatgtcggcgtctttctaaagagagatgacagcaatgagtcggatgtggtcgag
agcctggatgaaatctaccacacggggacgtttgcccagatccatgagatgcaggacctt
ggggacaagctgcgcatgatcgtcatgggacacagaagagtccatatcagcagacagctg
gaggtggagcccgaggagccggaggcggagaacaagcacaagccccgcaggaagtcaaag
cggggcaagaaggaggcggaggacgagctgagcgccaggcacccggcggagctggcgatg
gagcccacccctgagctcccggctgaggtgctcatggtggaggtagagaacgttgtccac
gaggacttccaggtcacggaggaggtgaaagccctgactgcagagatcgtgaagaccatc
cgggacatcattgccttgaaccctctctacagggagtcagtgctgcagatgatgcaggct
ggccagcgggtggtggacaaccccatctacctgagcgacatgggcgccgcgctcaccggg
gccgagtcccatgagctgcaggacgtcctggaagagaccaatattcctaagcggctgtac
aaggccctctccctgctgaagaaggaatttgaactgagcaagctgcagcagcgcctgggg
cgggaggtggaggagaagatcaagcagacccaccgtaagtacctgctgcaggagcagcta
aagatcatcaagaaggagctgggcctggagaaggacgacaaggatgccatcgaggagaag
ttccgggagcgcctgaaggagctcgtggtccccaagcacgtcatggatgttgtggacgag
gagctgagcaagctgggcctgctggacaaccactcctcggagttcaatgtcacccgcaac
tacctagactggctcacgtccatcccttggggcaagtacagcaacgagaacctggacctg
gcgcgggcacaggcagtgctggaggaagaccactacggcatggaggacgtcaagaaacgc
atcctggagttcattgccgttagccagctccgcggctccacccagggcaagatcctctgc
ttctatggcccccctggcgtgggtaagaccagcattgctcgctccatcgcccgcgccctg
aaccgagagtacttccgcttcagcgtcgggggcatgactgacgtggctgagatcaagggc
cacaggcggacctacgtgggcgccatgcccgggaagatcatccagtgtttgaagaagacc
aagacggagaaccccctgatcctcatcgacgaggtggacaagatcggccgaggctaccag
ggggacccgtcgtcggcactgctggagctgctggacccagagcagaatgccaacttcctg
gaccactacctggacgtgcccgtggacttgtccaaggtgctgttcatctgcacggccaac
gtcacggacaccatccccgagccgctgcgagaccgtatggagatgatcaacgtgtcgggc
tacgtggcccaggagaagctggccattgcggagcgctacctggtgccccaggctcgcgcc
ctgtgtggcttggatgagagcaaggccaagctgtcatcggacgtgctgacgctgctcatc
aagcagtactgccgcgagagcggtgtccgcaacctgcagaagcaagtggagaaggtgtta
cggaaatcggcctacaagattgtcagcggcgaggccgagtccgtggaggtgacgcccgag
aacctgcaggacttcgtggggaagcccgtgttcaccgtggagcgcatgtatgacgtgaca
ccgcccggcgtggtcatggggctggcctggaccgcaatgggaggctccacgctgtttgtg
gagacatccctgagacggccacaggacaaggatgccaagggtgacaaggatggcagcctg
gaggtgacaggccagctgggggaggtgatgaaggagagcgcccgcatagcctacaccttc
gccagagccttcctcatgcagcacgcccccgccaatgactacctggtgacctcacacatc
cacctgcatgtgcccgagggcgccacccccaaggacggcccaagcgcaggctgcaccatc
gtcacggccctgctgtccctggccatgggcaggcctgtccggcagaatctggccatgact
ggcgaagtctccctcacgggcaagatcctgcctgttggtggcatcaaggagaagaccatt
gcggccaagcgcgcaggggtgacgtgcatcgtcctgccagccgagaacaagaaggacttc
tacgacctggcagccttcatcaccgagggcctggaggtgcacttcgtggaacactaccgg
gagatcttcgacatcgccttcccggacgagcaggcagaggcgctggccgtggaacggtga

  All links  
Disease (2)   
   OMIM (2)   
Gene (29)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (34)   
   RefSeq(nuc) (8)   
   GenBank (13)   
   EMBL (13)   
3D Structure (28)   
   PDB (28)   
Protein domain (33)   
   Pfam (33)   
All databases (135)   

Download RDF
DBGET integrated database retrieval system