KEGG   Homo sapiens (human): 9429Help
Entry
9429              CDS       T01001                                 

Gene name
ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR-1, MXR1, UAQTL1
Definition
(RefSeq) ATP binding cassette subfamily G member 2 (Junior blood group)
  KO
K05681  ATP-binding cassette, subfamily G (WHITE), member 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa01523  Antifolate resistance
hsa02010  ABC transporters
hsa04976  Bile secretion
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    9429 (ABCG2)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    9429 (ABCG2)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    9429 (ABCG2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    9429 (ABCG2)
   04147 Exosome [BR:hsa04147]
    9429 (ABCG2)
   04090 CD molecules [BR:hsa04090]
    9429 (ABCG2)
Transporters [BR:hsa02000]
 ABC Transporters, Eukaryotic Type
  ABCG (White) subfamily
   ABCG2, 3 subgroups
    9429 (ABCG2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   9429 (ABCG2)
CD molecules [BR:hsa04090]
 Proteins
  9429 (ABCG2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: ABC2_membrane ABC_tran AAA_21 SMC_N ABC2_membrane_3 AAA_23 RsgA_GTPase AAA_29
Motif
Other DBs
NCBI-GeneID: 9429
NCBI-ProteinID: NP_004818
OMIM: 603756
HGNC: 74
Ensembl: ENSG00000118777
Vega: OTTHUMG00000130601
Pharos: Q9UNQ0(Tchem)
UniProt: Q9UNQ0 A0A024RDD4
Structure
PDB: 

Position
4q22.1
AA seq 655 aa AA seqDB search
MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE
KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN
SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT
QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF
SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING
DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK
ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS
TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP
MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL
MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN
NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS
NT seq 1968 nt NT seq  +upstreamnt  +downstreamnt
atgtcttccagtaatgtcgaagtttttatcccagtgtcacaaggaaacaccaatggcttc
cccgcgacagcttccaatgacctgaaggcatttactgaaggagctgtgttaagttttcat
aacatctgctatcgagtaaaactgaagagtggctttctaccttgtcgaaaaccagttgag
aaagaaatattatcgaatatcaatgggatcatgaaacctggtctcaacgccatcctggga
cccacaggtggaggcaaatcttcgttattagatgtcttagctgcaaggaaagatccaagt
ggattatctggagatgttctgataaatggagcaccgcgacctgccaatttcaaatgtaat
tcaggttacgtggtacaagatgatgttgtgatgggcactctgacggtgagagaaaactta
cagttctcagcagctcttcggcttgcaacaactatgacgaatcatgaaaaaaacgaacgg
attaacagggtcattcaagagttaggtctggataaagtggcagactccaaggttggaact
cagtttatccgtggtgtgtctggaggagaaagaaaaaggactagtataggaatggagctt
atcactgatccttccatcttgttcttggatgagcctacaactggcttagactcaagcaca
gcaaatgctgtccttttgctcctgaaaaggatgtctaagcagggacgaacaatcatcttc
tccattcatcagcctcgatattccatcttcaagttgtttgatagcctcaccttattggcc
tcaggaagacttatgttccacgggcctgctcaggaggccttgggatactttgaatcagct
ggttatcactgtgaggcctataataaccctgcagacttcttcttggacatcattaatgga
gattccactgctgtggcattaaacagagaagaagactttaaagccacagagatcatagag
ccttccaagcaggataagccactcatagaaaaattagcggagatttatgtcaactcctcc
ttctacaaagagacaaaagctgaattacatcaactttccgggggtgagaagaagaagaag
atcacagtcttcaaggagatcagctacaccacctccttctgtcatcaactcagatgggtt
tccaagcgttcattcaaaaacttgctgggtaatccccaggcctctatagctcagatcatt
gtcacagtcgtactgggactggttataggtgccatttactttgggctaaaaaatgattct
actggaatccagaacagagctggggttctcttcttcctgacgaccaaccagtgtttcagc
agtgtttcagccgtggaactctttgtggtagagaagaagctcttcatacatgaatacatc
agcggatactacagagtgtcatcttatttccttggaaaactgttatctgatttattaccc
atgaggatgttaccaagtattatatttacctgtatagtgtacttcatgttaggattgaag
ccaaaggcagatgccttcttcgttatgatgtttacccttatgatggtggcttattcagcc
agttccatggcactggccatagcagcaggtcagagtgtggtttctgtagcaacacttctc
atgaccatctgttttgtgtttatgatgattttttcaggtctgttggtcaatctcacaacc
attgcatcttggctgtcatggcttcagtacttcagcattccacgatatggatttacggct
ttgcagcataatgaatttttgggacaaaacttctgcccaggactcaatgcaacaggaaac
aatccttgtaactatgcaacatgtactggcgaagaatatttggtaaagcagggcatcgat
ctctcaccctggggcttgtggaagaatcacgtggccttggcttgtatgattgttattttc
ctcacaattgcctacctgaaattgttatttcttaaaaaatattcttaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (3)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (13)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (192)   
   RefSeq(nuc) (10)   
   GenBank (91)   
   EMBL (91)   
Protein domain (8)   
   Pfam (8)   
All databases (240)   

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