KEGG   Homo sapiens (human): 9429Help
Entry
9429              CDS       T01001                                 

Gene name
ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR-1, MXR1, UAQTL1
Definition
(RefSeq) ATP binding cassette subfamily G member 2 (Junior blood group)
  KO
K05681  ATP-binding cassette, subfamily G (WHITE), member 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa01523  Antifolate resistance
hsa02010  ABC transporters
hsa04976  Bile secretion
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    9429 (ABCG2)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    9429 (ABCG2)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    9429 (ABCG2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    9429 (ABCG2)
   04147 Exosome [BR:hsa04147]
    9429 (ABCG2)
   04090 CD molecules [BR:hsa04090]
    9429 (ABCG2)
Transporters [BR:hsa02000]
 ABC transporters, eukaryotic type
  ABCG (White) subfamily
   ABCG2, 3 subgroups
    9429 (ABCG2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   9429 (ABCG2)
CD molecules [BR:hsa04090]
 Proteins
  9429 (ABCG2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: ABC2_membrane ABC_tran AAA_21 SMC_N ABC2_membrane_3 AAA_23 RsgA_GTPase AAA_29
Motif
Other DBs
NCBI-GeneID: 9429
NCBI-ProteinID: NP_004818
OMIM: 603756
HGNC: 74
Ensembl: ENSG00000118777
Vega: OTTHUMG00000130601
Pharos: Q9UNQ0(Tchem)
UniProt: Q9UNQ0 A0A024RDD4
Structure
PDB: 

Position
4q22.1
AA seq 655 aa AA seqDB search
MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVE
KEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCN
SGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGT
QFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIF
SIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIING
DSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKK
ITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDS
TGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLP
MRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLL
MTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGN
NPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS
NT seq 1968 nt NT seq  +upstreamnt  +downstreamnt
atgtcttccagtaatgtcgaagtttttatcccagtgtcacaaggaaacaccaatggcttc
cccgcgacagcttccaatgacctgaaggcatttactgaaggagctgtgttaagttttcat
aacatctgctatcgagtaaaactgaagagtggctttctaccttgtcgaaaaccagttgag
aaagaaatattatcgaatatcaatgggatcatgaaacctggtctcaacgccatcctggga
cccacaggtggaggcaaatcttcgttattagatgtcttagctgcaaggaaagatccaagt
ggattatctggagatgttctgataaatggagcaccgcgacctgccaatttcaaatgtaat
tcaggttacgtggtacaagatgatgttgtgatgggcactctgacggtgagagaaaactta
cagttctcagcagctcttcggcttgcaacaactatgacgaatcatgaaaaaaacgaacgg
attaacagggtcattcaagagttaggtctggataaagtggcagactccaaggttggaact
cagtttatccgtggtgtgtctggaggagaaagaaaaaggactagtataggaatggagctt
atcactgatccttccatcttgttcttggatgagcctacaactggcttagactcaagcaca
gcaaatgctgtccttttgctcctgaaaaggatgtctaagcagggacgaacaatcatcttc
tccattcatcagcctcgatattccatcttcaagttgtttgatagcctcaccttattggcc
tcaggaagacttatgttccacgggcctgctcaggaggccttgggatactttgaatcagct
ggttatcactgtgaggcctataataaccctgcagacttcttcttggacatcattaatgga
gattccactgctgtggcattaaacagagaagaagactttaaagccacagagatcatagag
ccttccaagcaggataagccactcatagaaaaattagcggagatttatgtcaactcctcc
ttctacaaagagacaaaagctgaattacatcaactttccgggggtgagaagaagaagaag
atcacagtcttcaaggagatcagctacaccacctccttctgtcatcaactcagatgggtt
tccaagcgttcattcaaaaacttgctgggtaatccccaggcctctatagctcagatcatt
gtcacagtcgtactgggactggttataggtgccatttactttgggctaaaaaatgattct
actggaatccagaacagagctggggttctcttcttcctgacgaccaaccagtgtttcagc
agtgtttcagccgtggaactctttgtggtagagaagaagctcttcatacatgaatacatc
agcggatactacagagtgtcatcttatttccttggaaaactgttatctgatttattaccc
atgaggatgttaccaagtattatatttacctgtatagtgtacttcatgttaggattgaag
ccaaaggcagatgccttcttcgttatgatgtttacccttatgatggtggcttattcagcc
agttccatggcactggccatagcagcaggtcagagtgtggtttctgtagcaacacttctc
atgaccatctgttttgtgtttatgatgattttttcaggtctgttggtcaatctcacaacc
attgcatcttggctgtcatggcttcagtacttcagcattccacgatatggatttacggct
ttgcagcataatgaatttttgggacaaaacttctgcccaggactcaatgcaacaggaaac
aatccttgtaactatgcaacatgtactggcgaagaatatttggtaaagcagggcatcgat
ctctcaccctggggcttgtggaagaatcacgtggccttggcttgtatgattgttattttc
ctcacaattgcctacctgaaattgttatttcttaaaaaatattcttaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (3)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (13)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (192)   
   RefSeq(nuc) (10)   
   GenBank (91)   
   EMBL (91)   
Protein domain (8)   
   Pfam (8)   
All databases (239)   

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