KEGG   Homo sapiens (human): 9509
Entry
9509              CDS       T01001                                 

Gene name
ADAMTS2, ADAM-TS2, ADAMTS-2, ADAMTS-3, EDSDERMS, NPI, PC_I-NP, PCI-NP, PCINP, PCPNI, PNPI
Definition
(RefSeq) ADAM metallopeptidase with thrombospondin type 1 motif 2
  KO
K08618  a disintegrin and metalloproteinase with thrombospondin motifs 2 [EC:3.4.24.14]
Organism
hsa  Homo sapiens (human)
Disease
H02244  Ehlers-Danlos syndrome dermatospraxis type
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    9509 (ADAMTS2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.14  procollagen N-endopeptidase
     9509 (ADAMTS2)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M12: astacin/adamalysin family
   9509 (ADAMTS2)
SSDB
Motif
Pfam: Pep_M12B_propep ADAM_spacer1 TSP1_ADAMTS TSP_1 Reprolysin ADAM_CR_2 Reprolysin_5 Reprolysin_3 Reprolysin_2 TSP1_spondin Reprolysin_4 TSP1_CCN Peptidase_M10 PLAC DUF4953
Other DBs
NCBI-GeneID: 9509
NCBI-ProteinID: NP_055059
OMIM: 604539
HGNC: 218
Ensembl: ENSG00000087116
Vega: OTTHUMG00000130915
Pharos: O95450(Tbio)
UniProt: O95450
Position
5q35.3
AA seq 1211 aa
MDPPAGAARRLLCPALLLLLLLLPPPLLPPPPPPANARLAAAADPPGGPLGHGAERILAV
PVRTDAQGRLVSHVVSAATSRAGVRARRAAPVRTPSFPGGNEEEPGSHLFYNVTVFGRDL
HLRLRPNARLVAPGATMEWQGEKGTTRVEPLLGSCLYVGDVAGLAEASSVALSNCDGLAG
LIRMEEEEFFIEPLEKGLAAQEAEQGRVHVVYRRPPTSPPLGGPQALDTGASLDSLDSLS
RALGVLEEHANSSRRRARRHAADDDYNIEVLLGVDDSVVQFHGKEHVQKYLLTLMNIVNE
IYHDESLGAHINVVLVRIILLSYGKSMSLIEIGNPSQSLENVCRWAYLQQKPDTGHDEYH
DHAIFLTRQDFGPSGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDG
QGNRCGDEVRLGSIMAPLVQAAFHRFHWSRCSQQELSRYLHSYDCLLDDPFAHDWPALPQ
LPGLHYSMNEQCRFDFGLGYMMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTMCA
PGKHCFKGHCIWLTPDILKRDGSWGAWSPFGSCSRTCGTGVKFRTRQCDNPHPANGGRTC
SGLAYDFQLCSRQDCPDSLADFREEQCRQWDLYFEHGDAQHHWLPHEHRDAKERCHLYCE
SRETGEVVSMKRMVHDGTRCSYKDAFSLCVRGDCRKVGCDGVIGSSKQEDKCGVCGGDNS
HCKVVKGTFTRSPKKHGYIKMFEIPAGARHLLIQEVDATSHHLAVKNLETGKFILNEEND
VDASSKTFIAMGVEWEYRDEDGRETLQTMGPLHGTITVLVIPVGDTRVSLTYKYMIHEDS
LNVDDNNVLEEDSVVYEWALKKWSPCSKPCGGGSQFTKYGCRRRLDHKMVHRGFCAALSK
PKAIRRACNPQECSQPVWVTGEWEPCSQTCGRTGMQVRSVRCIQPLHDNTTRSVHAKHCN
DARPESRRACSRELCPGRWRAGPWSQCSVTCGNGTQERPVLCRTADDSFGICQEERPETA
RTCRLGPCPRNISDPSKKSYVVQWLSRPDPDSPIRKISSKGHCQGDKSIFCRMEVLSRYC
SIPGYNKLCCKSCNLYNNLTNVEGRIEPPPGKHNDIDVFMPTLPVPTVAMEVRPSPSTPL
EVPLNASSTNATEDHPETNAVDEPYKIHGLEDEVQPPNLIPRRPSPYEKTRNQRIQELID
EMRKKEMLGKF
NT seq 3636 nt   +upstreamnt  +downstreamnt
atggatccgccggcgggagccgctcgccgcctgctctgccccgcgctgctgctgctgctg
ctgctgctgccgccgccgctcctgccgccgccgccgccgcccgcgaacgccaggctcgcc
gccgccgccgaccccccaggcgggcccctggggcacggagcggagcgcatcctggcggtg
cccgtgcgcactgacgcccagggccgcttggtgtcccacgtggtgtcggcagctacgtcc
agagcaggggtacgagcccgcagggccgccccggtccggaccccgagcttccccggaggc
aacgaggaggagcctggcagtcacctcttctacaatgtcacggtctttggccgagacctg
cacctgcggctgcggcccaacgcccgcctcgtggcgcccggggccactatggagtggcag
ggcgagaagggcaccacccgcgtggagcccctgctcgggagctgtctctacgtcggagac
gtggccggcctagccgaagcctcctctgtggcgctcagcaactgcgatgggctggctggt
ctgatccggatggaggaggaggagttcttcatcgaacccttggagaaggggctggcggcg
caggaggctgagcaaggccgtgtgcatgtggtgtatcgccggccacccacgtcccctcct
ctcggggggccacaggccctggacacaggggcctccctggacagcctggacagcctcagc
cgcgccctgggcgtcctagaggagcacgccaacagctcgaggcggagggcacgcaggcat
gctgcggacgatgactacaacatcgaggtcctgctgggcgtggatgactctgtggtgcag
ttccacgggaaggagcacgtacagaagtacctgctgacactcatgaacattgtcaatgaa
atctaccatgacgagtccttgggtgcccacatcaacgtggtcctggtgcggatcatcctc
ctgagctatggaaagtccatgagcctcatcgagatcgggaacccctctcagagcctggag
aatgtctgccgctgggcctacctccagcagaagccagacacgggccacgatgaataccac
gatcacgccatcttcctcacacggcaggactttgggccttccggcatgcaaggctatgct
cctgtcaccggcatgtgccatccggtccgcagctgcaccctgaaccatgaggacggcttc
tcctcagcgtttgtggtggcccatgagactggccacgtgctgggcatggagcacgacggg
cagggcaaccgctgtggcgacgaggtgcggctgggcagcatcatggcgcccctggtgcag
gccgccttccaccgcttccactggtcccgctgcagccagcaggagctgagccgctacctg
cactcctatgactgcctgctggatgaccccttcgcccacgactggccggcgctgccccag
ctcccgggactgcactactccatgaacgagcaatgccgctttgacttcggcctgggctac
atgatgtgcacggcgttccggacctttgacccctgcaagcagctgtggtgcagccatcct
gacaacccctacttttgcaagaccaagaaggggccccccttggacgggactatgtgtgca
cctggcaagcattgttttaaaggacactgcatctggctgacacctgacatcctcaaacgg
gacggcagctggggcgcttggagtccgtttggctcctgctcacgtacctgtggcacgggc
gtgaagttcaggacccgccagtgtgacaacccacacccggccaacgggggccgcacctgc
tcgggccttgcctacgacttccagctctgcagccgccaggactgccccgactccctggct
gacttccgcgaggagcagtgccgccagtgggacctgtacttcgagcacggcgacgcccag
caccactggctgccccacgagcaccgggatgccaaggagagatgccacctgtactgcgag
tccagggagaccggggaggtggtgtccatgaagcgcatggtgcatgacgggacgcgctgc
tcctacaaggacgccttcagcctctgtgtgcgcggggactgcaggaaggtgggctgtgac
ggtgtgatcggctccagcaagcaggaagacaagtgtggcgtgtgcggaggggacaacagc
cactgcaaagtggtcaagggcacgttcacacggtcacccaagaagcatggttacatcaag
atgtttgagatccctgcaggagccagacacctgctcattcaggaggtagacgccaccagc
caccatctggccgtcaagaacctggagacaggcaagttcatcttaaatgaagagaatgac
gtggatgccagttccaaaaccttcattgccatgggcgtggagtgggagtacagagacgag
gacggccgggagacgctgcagaccatgggccccctccacggcaccatcaccgttctggtc
atcccggtgggagacacccgggtctcactgacgtacaaatacatgatccatgaggactca
ctgaatgtcgacgacaacaacgtcctggaagaggactctgtggtctacgagtgggccctg
aagaagtggtctccgtgctccaagccctgtggcggagggtcccagttcaccaagtatggc
tgccgccggaggctggaccacaagatggtacaccgtggcttctgtgccgccctctcgaag
cccaaagccatccgcagagcgtgcaacccacaggaatgctcccagccagtgtgggtcaca
ggcgaatgggagccatgtagccagacctgtgggcggacaggcatgcaggtgcgctccgtg
cgctgcattcagccgctacacgacaacaccacccgctccgtgcacgccaagcactgcaat
gacgcccggcccgagagccgccgggcctgcagccgcgagctctgccctggtcgttggcga
gccgggccctggtcccagtgctcagtaacctgtggcaacggcacccaggagcggccagtg
ctctgccgcaccgcggacgacagcttcggcatctgccaggaggagcgtcctgagacagcg
aggacctgcaggcttggcccctgtccccgaaacatctcagatccctccaagaagagctac
gtagttcagtggctgtcccgcccggaccccgactcgcccatccggaagatctcgtcaaag
ggccactgccaaggcgacaagtcaatattctgtaggatggaagtcttgtcccgctattgc
tccatcccaggctacaacaagctgtgctgcaagtcctgtaacctgtacaacaacctcacc
aacgtggagggcaggatagagccaccgcctgggaagcacaacgacattgacgtgttcatg
cctaccctcccagtgcccactgtagccatggaggtgcggccatcaccaagcacccccctg
gaggtccctctcaatgcctccagcaccaatgccacagaggatcacccagaaaccaatgcc
gtagatgaaccctacaaaatccatggcctggaagatgaagtccagccacccaacctaatc
cctcgacgaccgagcccctatgaaaagaccagaaaccaaagaatccaagagctcattgat
gagatgcggaagaaagagatgctcggaaagttctaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (26)   
   RefSeq(nuc) (2)   
   GenBank (12)   
   EMBL (12)   
Protein domain (15)   
   Pfam (15)   
All databases (84)   

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