KEGG   Homo sapiens (human): 9654
Entry
9654              CDS       T01001                                 
Symbol
TTLL4
Name
(RefSeq) tubulin tyrosine ligase like 4
  KO
K16601  tubulin polyglutamylase TTLL4 [EC:6.3.2.62]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    9654 (TTLL4)
   04812 Cytoskeleton proteins [BR:hsa04812]
    9654 (TTLL4)
Enzymes [BR:hsa01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.62  beta-tubulin-glutamate ligase
     9654 (TTLL4)
Cilium and associated proteins [BR:hsa03037]
 Primary cilia and associated proteins
  Tubulin polyglutamylase and associated proteins
   9654 (TTLL4)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Tubulin modification proteins
     Tubulin polyglutamylases
      9654 (TTLL4)
SSDB
Motif
Pfam: TTL ATPgrasp_YheCD ATPgrasp_ST
Other DBs
NCBI-GeneID: 9654
NCBI-ProteinID: NP_055455
OMIM: 618738
HGNC: 28976
Ensembl: ENSG00000135912
UniProt: Q14679
Structure
Position
2:218710835..218759724
AA seq 1199 aa
MASAGTQHYSIGLRQKNSFKQSGPSGTVPATPPEKPSEGRVWPQAHQQVKPIWKLEKKQV
ETLSAGLGPGLLGVPPQPAYFFCPSTLCSSGTTAVIAGHSSSCYLHSLPDLFNSTLLYRR
SSYRQKPYQQLESFCLRSSPSEKSPFSLPQKSLPVSLTANKATSSMVFSMAQPMASSSTE
PYLCLAAAGENPSGKSLASAISGKIPSPLSSSYKPMLNNNSFMWPNSTPVPLLQTTQGLK
PVSPPKIQPVSWHHSGGTGDCAPQPVDHKVPKSIGTVPADASAHIALSTASSHDTSTTSV
ASSWYNRNNLAMRAEPLSCALDDSSDSQDPTKEIRFTEAVRKLTARGFEKMPRQGCQLEQ
SSFLNPSFQWNVLNRSRRWKPPAVNQQFPQEDAGSVRRVLPGASDTLGLDNTVFCTKRIS
IHLLASHASGLNHNPACESVIDSSAFGEGKAPGPPFPQTLGIANVATRLSSIQLGQSEKE
RPEEARELDSSDRDISSATDLQPDQAETEDTEEELVDGLEDCCSRDENEEEEGDSECSSL
SAVSPSESVAMISRSCMEILTKPLSNHEKVVRPALIYSLFPNVPPTIYFGTRDERVEKLP
WEQRKLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCWGHHMKSPSFRSIREHQKLN
HFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKLLRKAWESSSRQKWIV
KPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIY
LFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANADEMACQGHKWALKALW
NYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPYSCHELFGFDIMLDENL
KPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNLAGFVLPNAEDIISSPSSCSSSTTSLP
TSPGDKCRMAPEHVTAQKMKKAYYLTQKIPDQDFYASVLDVLTPDDVRILVEMEDEFSRR
GQFERIFPSHISSRYLRFFEQPRYFNILTTQWEQKYHGNKLKGVDLLRSWCYKGFHMGVV
SDSAPVWSLPTSLLTISKDDVILNAFSKSETSKLGKQSSCEVSLLLSEDGTTPKSKKTQA
GLSPYPQKPSSSKDSEDTSKEPSLSTQTLPVIKCSGQTSRLSASSTFQSISDSLLAVSP
NT seq 3600 nt   +upstreamnt  +downstreamnt
atggcctcagcaggaacacagcactatagtattggcctccgccagaaaaacagcttcaag
cagagtggtccctcaggcacagtacctgccacgccacctgagaaaccctcggagggcaga
gtctggcctcaggcccatcagcaagtgaagccaatctggaagctggaaaagaagcaagtg
gagacactgtcagcagggttgggcccaggcctcttgggcgtcccaccccagccagcatat
ttcttttgccccagcactttatgtagctctgggaccacggctgtcattgcaggccacagc
agttcctgttacctacactctctcccggacttgttcaacagcaccctgctataccgccgc
tccagctataggcaaaaaccgtaccagcaactggagtctttctgcttgcgttcgagcccg
tcagaaaaaagccctttttctctccctcaaaagagcctccctgtcagtctcactgccaac
aaggccacttcttccatggtcttctccatggcccagcccatggcctcctcatccacagaa
ccatacctctgcttggcagcggctggggaaaacccttcagggaagagcctggcctctgcc
atctcagggaagatcccatctccactctcttcctcctataagcccatgctgaataataat
tccttcatgtggccaaatagcacgccagtgcctttattgcagaccacacagggcctgaag
ccagtatcgccacccaagatccagcctgtctcctggcatcattcagggggtactggagac
tgtgcaccgcagcctgttgaccataaggtgcccaaaagcattggcactgtcccagctgat
gccagtgcccatatcgccttgtctaccgctagctcccacgacacatccaccaccagtgtt
gcctcttcctggtataaccggaataacttagccatgagggcagagccactttcctgtgct
ctggatgacagctctgattcccaggatccaactaaggagattcggttcactgaggccgtg
aggaaattgaccgcaagaggctttgagaagatgccgaggcaaggctgccagcttgaacag
tctagtttcctgaaccccagcttccagtggaatgtcctcaacaggagcaggcggtggaaa
cctcctgcggtaaatcagcagtttcctcaggaggatgctggatcggtcaggcgggtcctc
cctggtgcctcagataccttggggttggacaatacagtcttctgtaccaagcgtatcagc
attcacctccttgcctcacatgccagtgggctcaatcacaaccctgcctgtgaatctgta
attgactcctcagcatttggagaaggcaaagctccaggtcccccttttcctcaaactctt
ggcatagccaacgtggccacccgcctctcttccatccagctgggccagtctgagaaggag
agacctgaggaggccagggagctggactcatctgatagggatattagttcagctactgac
ctccagccagatcaggctgagactgaagatacagaagaagaactagtagatggtttggaa
gactgttgtagccgtgatgagaatgaagaggaggagggagactcagagtgctcctcatta
agtgctgtctcccccagcgaatcggtggccatgatctctagaagctgtatggaaattctg
accaaacccctttccaatcatgagaaagttgtccgaccagccctcatctacagtctcttt
cccaacgttccccctaccatctattttggcactcgggatgagagagtggagaaacttccc
tgggaacagaggaagttgctccgatggaagatgagcacagtgacccccaacattgtcaag
cagaccattggacggtcccacttcaaaatcagcaaaagaaacgatgactggctgggctgc
tggggtcaccacatgaagtctcctagtttccgatccattcgagagcatcagaagctaaac
catttcccaggctcattccagattgggaggaaggaccggctatggcggaacctgtcacgt
atgcagagccgctttggcaagaaggagttcagtttcttcccccagtcctttatcctgccc
caggacgccaagctcctgcgcaaagcgtgggagagcagcagccgccaaaagtggattgtg
aagccaccagcatcagctcgaggcattggcatccaggttattcacaagtggagtcagctc
cccaagcgaaggcccctcctggtacagaggtatctacacaaaccctacctcatcagcggc
agcaagtttgacctgcggatctatgtttatgtcacttcctacgatcctctgcggatttac
ctcttttcagatggactggtccgctttgccagttgcaagtattcgccttccatgaagagc
cttggcaataagttcatgcacctgaccaactacagtgtcaataaaaagaatgccgagtac
caggccaatgcagatgaaatggcttgccagggccacaaatgggcactgaaggctttgtgg
aactacctgagccagaagggagtcaatagcgacgccatctgggagaagataaaggatgtt
gttgtcaaaactatcatctcgtcagagccctatgtgaccagcctgctcaagatgtatgtg
cgacggccctatagctgccatgaactctttggttttgacatcatgctagacgaaaacctc
aagccctgggtcctggaagtcaacatttccccaagcctccactccagctctccactggat
atcagcatcaaaggccagatgattcgtgaccttctgaatctggcaggttttgtcctgccc
aatgcagaggatatcatttccagccccagcagctgcagcagctccaccaccagcctgccc
acctcccctggggacaaatgtcgaatggctccagagcatgtcactgcacagaagatgaag
aaagcctattatctgacccagaaaattcctgatcaggacttctatgcatctgtgctggat
gtcctgacaccagatgatgttcggattctggttgagatggaagatgagttttctcgccgt
ggtcagtttgaacgaatttttccttctcatatctcctctcgctatctccgcttttttgag
cagccacgatatttcaacattctcaccacccaatgggaacagaaataccatggcaacaag
cttaaaggagtagatctgctccggagttggtgctacaaagggttccacatgggagttgtc
tctgattctgctccagtgtggtctctcccgacatcacttctgactatctcaaaggatgac
gtgatactcaatgccttcagcaaatcagagactagcaagctgggaaaacaaagctcctgt
gaggttagcctactactctctgaagacgggaccacgcccaaatccaagaagactcaagct
ggcctttccccttatccccagaaacccagttcctcaaaggacagtgaggacaccagcaaa
gagcccagcctttctacccagacgttacctgtgatcaagtgctctgggcagacttcaaga
ctttctgcttcctccactttccagtcaatcagtgactccctcctggctgtgagcccataa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (42)   
   KEGG ORTHOLOGY (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (10)   
   OC (1)   
Protein sequence (33)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (31)   
DNA sequence (49)   
   RefSeq(nuc) (31)   
   GenBank (9)   
   EMBL (9)   
3D Structure (1)   
   PDB (1)   
Protein domain (3)   
   Pfam (3)   
All databases (135)   

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