KEGG   Homo sapiens (human): 970
Entry
970               CDS       T01001                                 
Symbol
CD70, CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A
Name
(RefSeq) CD70 molecule
  KO
K05470  tumor necrosis factor ligand superfamily member 7
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
Network
nt06516  TNF signaling
  Element
N01799  CD70-CD27 signaling pathway
Disease
H01970  Lymphoproliferative syndrome
Drug target
Vorsetuzumab: D10342
Vorsetuzumab mafodotin: D10341
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    970 (CD70)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hsa04052]
    970 (CD70)
   04090 CD molecules [BR:hsa04090]
    970 (CD70)
Cytokines and neuropeptides [BR:hsa04052]
 Cytokines
  Tumor necrosis fators
   970 (CD70)
CD molecules [BR:hsa04090]
 Proteins
  970 (CD70)
SSDB
Motif
Pfam: TNF
Other DBs
NCBI-GeneID: 970
NCBI-ProteinID: NP_001243
OMIM: 602840
HGNC: 11937
Ensembl: ENSG00000125726
UniProt: P32970 A0A0U5JA32
Structure
Position
19:complement(6581648..6591150)
AA seq 193 aa
MPEEGSGCSVRRRPYGCVLRAALVPLVAGLVICLVVCIQRFAQAQQQLPLESLGWDVAEL
QLNHTGPQQDPRLYWQGGPALGRSFLHGPELDKGQLRIHRDGIYMVHIQVTLAICSSTTA
SRHHPTTLAVGICSPASRSISLLRLSFHQGCTIASQRLTPLARGDTLCTNLTGTLLPSRN
TDETFFGVQWVRP
NT seq 582 nt   +upstreamnt  +downstreamnt
atgccggaggagggttcgggctgctcggtgcggcgcaggccctatgggtgcgtcctgcgg
gctgctttggtcccattggtcgcgggcttggtgatctgcctcgtggtgtgcatccagcgc
ttcgcacaggctcagcagcagctgccgctcgagtcacttgggtgggacgtagctgagctg
cagctgaatcacacaggacctcagcaggaccccaggctatactggcaggggggcccagca
ctgggccgctccttcctgcatggaccagagctggacaaggggcagctacgtatccatcgt
gatggcatctacatggtacacatccaggtgacgctggccatctgctcctccacgacggcc
tccaggcaccaccccaccaccctggccgtgggaatctgctctcccgcctcccgtagcatc
agcctgctgcgtctcagcttccaccaaggttgtaccattgcctcccagcgcctgacgccc
ctggcccgaggggacacactctgcaccaacctcactgggacacttttgccttcccgaaac
actgatgagaccttctttggagtgcagtgggtgcgcccctga

  All links  
Disease (2)   
   OMIM (2)   
Gene (18)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (16)   
   RefSeq(nuc) (4)   
   GenBank (6)   
   EMBL (6)   
3D Structure (1)   
   PDB (1)   
Protein domain (1)   
   Pfam (1)   
All databases (45)   

Download RDF
DBGET integrated database retrieval system