KEGG   Homo sapiens (human): 970Help
Entry
970               CDS       T01001                                 

Gene name
CD70, CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A
Definition
(RefSeq) CD70 molecule
  KO
K05470  tumor necrosis factor ligand superfamily member 7
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
Drug target
Vorsetuzumab: D10342
Vorsetuzumab mafodotin: D10341
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    970 (CD70)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:hsa04052]
    970 (CD70)
   04090 CD molecules [BR:hsa04090]
    970 (CD70)
Cytokines and growth factors [BR:hsa04052]
 Cytokines
  Tumor necrosis fators
   970 (CD70)
CD molecules [BR:hsa04090]
 Proteins
  970 (CD70)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: TNF
Motif
Other DBs
NCBI-GeneID: 970
NCBI-ProteinID: NP_001243
OMIM: 602840
HGNC: 11937
Ensembl: ENSG00000125726
Vega: OTTHUMG00000181834
Pharos: P32970(Tbio)
UniProt: P32970 A0A0U5JA32
Position
19p13.3
AA seq 193 aa AA seqDB search
MPEEGSGCSVRRRPYGCVLRAALVPLVAGLVICLVVCIQRFAQAQQQLPLESLGWDVAEL
QLNHTGPQQDPRLYWQGGPALGRSFLHGPELDKGQLRIHRDGIYMVHIQVTLAICSSTTA
SRHHPTTLAVGICSPASRSISLLRLSFHQGCTIASQRLTPLARGDTLCTNLTGTLLPSRN
TDETFFGVQWVRP
NT seq 582 nt NT seq  +upstreamnt  +downstreamnt
atgccggaggagggttcgggctgctcggtgcggcgcaggccctatgggtgcgtcctgcgg
gctgctttggtcccattggtcgcgggcttggtgatctgcctcgtggtgtgcatccagcgc
ttcgcacaggctcagcagcagctgccgctcgagtcacttgggtgggacgtagctgagctg
cagctgaatcacacaggacctcagcaggaccccaggctatactggcaggggggcccagca
ctgggccgctccttcctgcatggaccagagctggacaaggggcagctacgtatccatcgt
gatggcatctacatggtacacatccaggtgacgctggccatctgctcctccacgacggcc
tccaggcaccaccccaccaccctggccgtgggaatctgctctcccgcctcccgtagcatc
agcctgctgcgtctcagcttccaccaaggttgtaccattgcctcccagcgcctgacgccc
ctggcccgaggggacacactctgcaccaacctcactgggacacttttgccttcccgaaac
actgatgagaccttctttggagtgcagtgggtgcgcccctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (2)   
   OMIM (2)   
Drug (2)   
   KEGG DRUG (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (14)   
   RefSeq(nuc) (2)   
   GenBank (6)   
   EMBL (6)   
Protein domain (1)   
   Pfam (1)   
All databases (50)   

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