KEGG   Homo sapiens (human): 9742
Entry
9742              CDS       T01001                                 
Symbol
IFT140, CED5, MZSDS, PKD9, RP80, SRTD9, WDTC2, c305C8.4, c380F5.1, gs114
Name
(RefSeq) intraflagellar transport 140
  KO
K19672  intraflagellar transport protein 140
Organism
hsa  Homo sapiens (human)
Disease
H00527  Retinitis pigmentosa
H00529  Cranioectodermal dysplasia
H00542  Polycystic kidney disease
H02157  Short-rib thoracic dysplasia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    9742 (IFT140)
Cilium and associated proteins [BR:hsa03037]
 Primary cilia and associated proteins
  Intraflagellar transport (IFT) complex A
   9742 (IFT140)
SSDB
Motif
Pfam: TPR_IF140-IFT172 Beta-prop_IFT140_1st Beta-prop_IFT140_2nd TPR_IF140_C Beta-prop_EML_2 WD40_CDC20-Fz ANAPC4_WD40 Beta-prop_RIG_2nd WD40_WDHD1_1st Beta-prop_WDR19_1st Beta-prop_WDR90_POC16_2nd Beta-prop_EML WDR55 Beta-prop_HPS5 WD40_Prp19 TPR_GEMI5 Beta-prop_CAF1B_HIR1 TPR_IFT80_172 WD40 TPR_COPA_B Beta-prop_WDR75_1st PPR_2 tRNA_int_end_N2 WD40_MABP1-WDR62_1st SGL TPR_14
Other DBs
NCBI-GeneID: 9742
NCBI-ProteinID: NP_055529
OMIM: 614620
HGNC: 29077
Ensembl: ENSG00000187535
UniProt: Q96RY7
Structure
Position
16:complement(1510427..1612072)
AA seq 1462 aa
MALYYDHQIEAPDAAGSPSFISWHPVHPFLAVAYISTTSTGSVDIYLEQGECVPDTHVER
PFRVASLCWHPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLS
GDRLGVLLLWRLDQRGRVQGTPLLKHEYGKHLTHCIFRLPPPGEDLVQLAKAAVSGDEKA
LDMFNWKKSSSGSLLKMGSHEGLLFFVSLMDGTVHYVDEKGKTTQVVSADSTIQMLFYME
KREALVVVTENLRLSLYTVPPEGKAEEVMKVKLSGKTGRRADIALIEGSLLVMAVGEAAL
RFWDIERGENYILSPDEKFGFEKGENMNCVCYCKVKGLLAAGTDRGRVAMWRKVPDFLGS
PGAEGKDRWALQTPTELQGNITQIQWGSRKNLLAVNSVISVAILSERAMSSHFHQQVAAM
QVSPSLLNVCFLSTGVAHSLRTDMHISGVFATKDAVAVWNGRQVAIFELSGAAIRSAGTF
LCETPVLAMHEENVYTVESNRVQVRTWQGTVKQLLLFSETEGNPCFLDICGNFLVVGTDL
AHFKSFDLSRREAKAHCSCRSLAELVPGVGGIASLRCSSSGSTISILPSKADNSPDSKIC
FYDVEMDTVTVFDFKTGQIDRRETLSFNEQETNKSHLFVDEGLKNYVPVNHFWDQSEPRL
FVCEAVQETPRSQPQSANGQPQDGRAGPAADVLILSFFISEEHGFLLHESFPRPATSHSL
LGMEVPYYYFTRKPEEADREDEVEPGCHHIPQMVSRRPLRDFVGLEDCDKATRDAMLHFS
FFVTIGDMDEAFKSIKLIKSEAVWENMARMCVKTQRLDVAKVCLGNMGHARGARALREAE
QEPELEARVAVLATQLGMLEDAEQLYRKCKRHDLLNKFYQAAGRWQEALQVAEHHDRVHL
RSTYHRYAGHLEASADCSRALSYYEKSDTHRFEVPRMLSEDLPSLELYVNKMKDKTLWRW
WAQYLESQGEMDAALHYYELARDHFSLVRIHCFQGNVQKAAQIANETGNLAASYHLARQY
ESQEEVGQAVHFYTRAQAFKNAIRLCKENGLDDQLMNLALLSSPEDMIEAARYYEEKGVQ
MDRAVMLYHKAGHFSKALELAFATQQFVALQLIAEDLDETSDPALLARCSDFFIEHSQYE
RAVELLLAARKYQEALQLCLGQNMSITEEMAEKMTVAKDSSDLPEESRRELLEQIADCCM
RQGSYHLATKKYTQAGNKLKAMRALLKSGDTEKITFFASVSRQKEIYIMAANYLQSLDWR
KEPEIMKNIIGFYTKGRALDLLAGFYDACAQVEIDEYQNYDKAHGALTEAYKCLAKAKAK
SPLDQETRLAQLQSRMALVKRFIQARRTYTEDPKESIKQCELLLEEPDLDSTIRIGDVYG
FLVEHYVRKEEYQTAYRFLEEMRRRLPLANMSYYVSPQAVDAVHRGLGLPLPRTVPEQVR
HNSMEDARELDEEVVEEADDDP
NT seq 4389 nt   +upstreamnt  +downstreamnt
atggccctctattatgaccaccagatagaagccccggatgcagcagggtcaccctcattt
atcagctggcaccctgtccatccattcttggcagttgcttacatcagcacaacctcaaca
ggcagcgtggatatttacctggagcaaggggagtgcgtgccagatacacacgtcgagagg
ccgttccgggttgcttccctgtgctggcacccgacgcggctggtgctggctgtgggctgg
gagactggagaagtgacggtgtttaacaagcaggacaaggagcagcacacgatgcccctg
acacacacagccgacatcaccgtgctccgttggagccccagtggaaactgcctgctgtct
ggggacaggcttggtgtcttgctcttgtggaggttggaccaaaggggccgagtgcaaggg
acgcctctgctgaaacacgagtatgggaaacacctcacgcactgcatcttccggctcccc
cctcctggcgaggacctggttcagttggcaaaggcagctgtgagcggtgatgagaaagcc
ctggacatgtttaactggaagaagagcagttctggaagtttgctgaagatggggtctcac
gaggggctgttgttctttgtcagtctgatggacgggacagtgcactatgtggatgagaag
ggcaagaccactcaggtggtgtccgcagacagcacgattcagatgctgttctacatggag
aagagggaggcactggtggtggtcacagagaacctccggctgtccctgtacacggtgcct
cctgagggcaaagcagaagaagtgatgaaggtcaagctgagcgggaaaaccggccgccgg
gcagacatcgctttgattgaaggcagccttctcgtgatggccgtcggggaggctgccctc
agattctgggacatagaacgaggagagaattatatactgagtccagatgagaagtttggc
tttgagaaaggagagaatatgaactgtgtgtgttactgtaaagtcaaaggtcttctggcc
gctggtaccgacagagggcgagtagccatgtggaggaaagtaccagacttcctgggcagc
cccggggcagagggcaaggacaggtgggcccttcagacccctaccgagctccaaggaaac
atcacgcaaatccagtggggttccaggaagaacctgctggcagtgaacagcgtcatctcc
gtggccatcctcagcgagcgggccatgtcgtcacacttccaccagcaagtggccgccatg
caggtctccccgagtctgctgaatgtgtgcttcctgtccacgggggtcgcacacagcctg
cgcaccgacatgcacatcagtggagtgtttgccaccaaggatgctgtcgcagtctggaac
ggaaggcaggtggcgatcttcgagctttctggagccgcgatacggagtgcagggaccttc
ttgtgtgagacgcctgtgttagcaatgcatgaagaaaacgtttacacggtggagtcaaac
cgagttcaagttcgaacctggcaggggactgtcaaacaactcctccttttctcggagact
gaggggaatccctgcttcttggacatctgtgggaatttcctggttgtagggacagacttg
gctcactttaaaagctttgatctttcccgaagagaggccaaagcacactgtagctgcagg
agcctggcggagctggtccctggggtggggggcatcgcttctctgcggtgcagcagcagc
gggagcaccatcagcatcctccccagcaaggctgacaacagccctgattccaaaatctgc
ttctacgatgttgaaatggacacagtgaccgtctttgacttcaagactggacaaattgat
cggagagagacgctgtcctttaatgagcaagagactaataagagccacctctttgtggat
gagggactgaaaaattatgttcccgtgaaccacttctgggaccagagtgagccccggctg
tttgtatgcgaagccgtgcaggagacgccgcgctcccagcctcagtctgcaaacgggcag
ccccaagatgggcgcgctggccctgcggcagatgttttgatcctgtccttcttcatttcc
gaagagcacggcttcctgcttcatgagagcttcccccggcctgccacctcccacagtctc
ctggggatggaagtgccttattactacttcacaagaaagcccgaagaagcagacagagaa
gacgaggtggagcctgggtgccaccacatccctcagatggtgtccaggagacccctgcga
gactttgtggggctggaggactgcgacaaggccacccgggacgccatgctccacttcagc
ttctttgtcaccataggagacatggacgaagccttcaaatccatcaagctcatcaaaagt
gaggccgtctgggagaacatggcgcgcatgtgcgtgaagacccagcggctggacgtggcc
aaggtgtgcctggggaacatgggccatgcccgcggggcccgagcgctgcgtgaggcggag
caggagccggagctagaggcccgcgtggccgtgctggccacgcagctgggcatgctggag
gacgccgagcagctgtacaggaagtgcaagcgccacgacctcctgaacaagttctaccag
gctgcgggccggtggcaggaggccctccaggtagccgagcaccacgatcgcgtgcacctg
cgcagcacctaccaccgctatgccgggcacctggaggccagcgccgactgcagccgggcc
ctcagttactacgagaagtcggacacgcaccgcttcgaggtgcccaggatgctgtcggag
gacctgccgtccctggagctctacgtgaataaaatgaaggataagaccctgtggcggtgg
tgggcgcagtacctggagagccagggcgagatggacgccgcgctgcactactacgagctg
gcccgggaccacttctccctggtccgcatccactgcttccagggcaatgtccagaaggct
gcgcaaatagccaacgagacaggaaacctggcggcctcctaccacctcgcccgccagtac
gagagccaggaggaggtcgggcaggcggtgcacttctacacccgggcacaggccttcaag
aatgccatccgcctgtgcaaggagaacggcctggacgaccagctcatgaacttggccctg
ctgagctcccccgaggacatgatcgaggcggcccgatactacgaggagaagggcgtgcag
atggacagggcggtcatgctgtaccacaaggctggccacttctccaaggccctggagctg
gcctttgccacccagcagtttgtggccctacagctcatagcagaggacctggatgagacg
tcagaccctgcgctcctggcccgctgctccgacttcttcatcgagcacagtcagtacgag
agggcggtagagctgctgctggctgccaggaagtatcaggaagccctgcagctgtgcctg
gggcagaacatgagcatcaccgaggagatggcggaaaagatgaccgtggccaaggactcc
tcggacctgcctgaggagtcgcggcgggagctgctggagcagatagcagactgctgcatg
cgccagggcagctaccacctggccaccaagaagtacacgcaggccggcaacaagctgaag
gccatgagggcgctgctcaaatccggagacacggagaaaatcacgttcttcgcgagcgtg
tccaggcagaaggaaatctacatcatggctgctaactacctgcagtccctggactggcgg
aaggagccggagatcatgaagaacatcatcggcttctacaccaaggggcgggccctggac
ctcctggctggcttttatgacgcttgtgcccaggtggagattgatgaataccagaactac
gacaaagcccacggggcgctgaccgaggcctacaagtgcctggccaaggccaaggccaag
agccccctggaccaggagaccaggctggcgcagctgcagagcaggatggcactggtgaag
aggttcatccaggcccgcaggacgtacacagaggaccccaaggagtccatcaagcagtgt
gagctgctcctggaggaaccagacctggacagcaccatccgcatcggggacgtctatggc
ttcctggtggagcactacgtgcggaaggaggaataccagacggcctacagattcctggag
gagatgcggcggcggcttcccttggccaacatgtcctactacgtgagcccgcaggccgtg
gacgccgtgcaccgggggctgggtctcccactgccacgcaccgtccccgagcaggtccgc
cacaacagcatggaggacgccagggagctggacgaggaggtggtggaagaggcagatgac
gacccctga

  All links  
Disease (5)   
   OMIM (5)   
Gene (22)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (53)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (51)   
DNA sequence (71)   
   RefSeq(nuc) (51)   
   GenBank (10)   
   EMBL (10)   
3D Structure (4)   
   PDB (4)   
Protein domain (26)   
   Pfam (26)   
All databases (181)   

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