KEGG   Homo sapiens (human): 9833
Entry
9833              CDS       T01001                                 

Gene name
MELK, HPK38
Definition
(RefSeq) maternal embryonic leucine zipper kinase
  KO
K08799  maternal embryonic leucine zipper kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    9833 (MELK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     9833 (MELK)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   9833 (MELK)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr KA1 Kinase-like Kdo APH Choline_kinase
Other DBs
NCBI-GeneID: 9833
NCBI-ProteinID: NP_055606
OMIM: 607025
HGNC: 16870
Ensembl: ENSG00000165304
Vega: OTTHUMG00000019906
Pharos: Q14680(Tchem)
UniProt: Q14680
Structure
PDB: 

Position
9p13.2
AA seq 651 aa
MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEA
LKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAV
AYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELI
QGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLL
QQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQT
MEDLISLWQYDHLTATYLLLLAKKARGKPVRLRLSSFSCGQASATPFTDIKSNNWSLEDV
TASDKNYVAGLIDYDWCEDDLSTGAATPRTSQFTKYWTESNGVESKSLTPALCRTPANKL
KNKENVYTPKSAVKNEEYFMFPEPKTPVNKNQHKREILTTPNRYTTPSKARNQCLKETPI
KIPVNSTGTDKLMTGVISPERRCRSVELDLNQAHMEETPKRKGAKVFGSLERGLDKVITV
LTRSKRKGSARDGPRRLKLHYNVTTTRLVNPDQLLNEIMSILPKKHVDFVQKGYTLKCQT
QSDFGKVTMQFELEVCQLQKPDVVGIRRQRLKGDAWVYKRLVEDILSSCKV
NT seq 1956 nt   +upstreamnt  +downstreamnt
atgaaagattatgatgaacttctcaaatattatgaattacatgaaactattgggacaggt
ggctttgcaaaggtcaaacttgcctgccatatccttactggagagatggtagctataaaa
atcatggataaaaacacactagggagtgatttgccccggatcaaaacggagattgaggcc
ttgaagaacctgagacatcagcatatatgtcaactctaccatgtgctagagacagccaac
aaaatattcatggttcttgagtactgccctggaggagagctgtttgactatataatttcc
caggatcgcctgtcagaagaggagacccgggttgtcttccgtcagatagtatctgctgtt
gcttatgtgcacagccagggctatgctcacagggacctcaagccagaaaatttgctgttt
gatgaatatcataaattaaagctgattgactttggtctctgtgcaaaacccaagggtaac
aaggattaccatctacagacatgctgtgggagtctggcttatgcagcacctgagttaata
caaggcaaatcatatcttggatcagaggcagatgtttggagcatgggcatactgttatat
gttcttatgtgtggatttctaccatttgatgatgataatgtaatggctttatacaagaag
attatgagaggaaaatatgatgttcccaagtggctctctcccagtagcattctgcttctt
caacaaatgctgcaggtggacccaaagaaacggatttctatgaaaaatctattgaaccat
ccctggatcatgcaagattacaactatcctgttgagtggcaaagcaagaatccttttatt
cacctcgatgatgattgcgtaacagaactttctgtacatcacagaaacaacaggcaaaca
atggaggatttaatttcactgtggcagtatgatcacctcacggctacctatcttctgctt
ctagccaagaaggctcggggaaaaccagttcgtttaaggctttcttctttctcctgtgga
caagccagtgctaccccattcacagacatcaagtcaaataattggagtctggaagatgtg
accgcaagtgataaaaattatgtggcgggattaatagactatgattggtgtgaagatgat
ttatcaacaggtgctgctactccccgaacatcacagtttaccaagtactggacagaatca
aatggggtggaatctaaatcattaactccagccttatgcagaacacctgcaaataaatta
aagaacaaagaaaatgtatatactcctaagtctgctgtaaagaatgaagagtactttatg
tttcctgagccaaagactccagttaataagaaccagcataagagagaaatactcactacg
ccaaatcgttacactacaccctcaaaagctagaaaccagtgcctgaaagaaactccaatt
aaaataccagtaaattcaacaggaacagacaagttaatgacaggtgtcattagccctgag
aggcggtgccgctcagtggaattggatctcaaccaagcacatatggaggagactccaaaa
agaaagggagccaaagtgtttgggagccttgaaagggggttggataaggttatcactgtg
ctcaccaggagcaaaaggaagggttctgccagagacgggcccagaagactaaagcttcac
tataacgtgactacaactagattagtgaatccagatcaactgttgaatgaaataatgtct
attcttccaaagaagcatgttgactttgtacaaaagggttatacactgaagtgtcaaaca
cagtcagattttgggaaagtgacaatgcaatttgaattagaagtgtgccagcttcaaaaa
cccgatgtggtgggtatcaggaggcagcggcttaagggcgatgcctgggtttacaaaaga
ttagtggaagacatcctatctagctgcaaggtataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (22)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (20)   
DNA sequence (61)   
   RefSeq(nuc) (21)   
   GenBank (20)   
   EMBL (20)   
Protein domain (7)   
   Pfam (7)   
All databases (116)   

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