KEGG   Homo sapiens (human): 9833
Entry
9833              CDS       T01001                                 
Symbol
MELK, HPK38
Name
(RefSeq) maternal embryonic leucine zipper kinase
  KO
K08799  maternal embryonic leucine zipper kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    9833 (MELK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     9833 (MELK)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   9833 (MELK)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr UBA_MELK KA1 Kinase-like ABC1 Kdo APH DUF5898
Other DBs
NCBI-GeneID: 9833
NCBI-ProteinID: NP_055606
OMIM: 607025
HGNC: 16870
Ensembl: ENSG00000165304
UniProt: Q14680
Structure
Position
9:36572895..36677682
AA seq 651 aa
MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEA
LKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAV
AYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELI
QGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLL
QQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQT
MEDLISLWQYDHLTATYLLLLAKKARGKPVRLRLSSFSCGQASATPFTDIKSNNWSLEDV
TASDKNYVAGLIDYDWCEDDLSTGAATPRTSQFTKYWTESNGVESKSLTPALCRTPANKL
KNKENVYTPKSAVKNEEYFMFPEPKTPVNKNQHKREILTTPNRYTTPSKARNQCLKETPI
KIPVNSTGTDKLMTGVISPERRCRSVELDLNQAHMEETPKRKGAKVFGSLERGLDKVITV
LTRSKRKGSARDGPRRLKLHYNVTTTRLVNPDQLLNEIMSILPKKHVDFVQKGYTLKCQT
QSDFGKVTMQFELEVCQLQKPDVVGIRRQRLKGDAWVYKRLVEDILSSCKV
NT seq 1956 nt   +upstreamnt  +downstreamnt
atgaaagattatgatgaacttctcaaatattatgaattacatgaaactattgggacaggt
ggctttgcaaaggtcaaacttgcctgccatatccttactggagagatggtagctataaaa
atcatggataaaaacacactagggagtgatttgccccggatcaaaacggagattgaggcc
ttgaagaacctgagacatcagcatatatgtcaactctaccatgtgctagagacagccaac
aaaatattcatggttcttgagtactgccctggaggagagctgtttgactatataatttcc
caggatcgcctgtcagaagaggagacccgggttgtcttccgtcagatagtatctgctgtt
gcttatgtgcacagccagggctatgctcacagggacctcaagccagaaaatttgctgttt
gatgaatatcataaattaaagctgattgactttggtctctgtgcaaaacccaagggtaac
aaggattaccatctacagacatgctgtgggagtctggcttatgcagcacctgagttaata
caaggcaaatcatatcttggatcagaggcagatgtttggagcatgggcatactgttatat
gttcttatgtgtggatttctaccatttgatgatgataatgtaatggctttatacaagaag
attatgagaggaaaatatgatgttcccaagtggctctctcccagtagcattctgcttctt
caacaaatgctgcaggtggacccaaagaaacggatttctatgaaaaatctattgaaccat
ccctggatcatgcaagattacaactatcctgttgagtggcaaagcaagaatccttttatt
cacctcgatgatgattgcgtaacagaactttctgtacatcacagaaacaacaggcaaaca
atggaggatttaatttcactgtggcagtatgatcacctcacggctacctatcttctgctt
ctagccaagaaggctcggggaaaaccagttcgtttaaggctttcttctttctcctgtgga
caagccagtgctaccccattcacagacatcaagtcaaataattggagtctggaagatgtg
accgcaagtgataaaaattatgtggcgggattaatagactatgattggtgtgaagatgat
ttatcaacaggtgctgctactccccgaacatcacagtttaccaagtactggacagaatca
aatggggtggaatctaaatcattaactccagccttatgcagaacacctgcaaataaatta
aagaacaaagaaaatgtatatactcctaagtctgctgtaaagaatgaagagtactttatg
tttcctgagccaaagactccagttaataagaaccagcataagagagaaatactcactacg
ccaaatcgttacactacaccctcaaaagctagaaaccagtgcctgaaagaaactccaatt
aaaataccagtaaattcaacaggaacagacaagttaatgacaggtgtcattagccctgag
aggcggtgccgctcagtggaattggatctcaaccaagcacatatggaggagactccaaaa
agaaagggagccaaagtgtttgggagccttgaaagggggttggataaggttatcactgtg
ctcaccaggagcaaaaggaagggttctgccagagacgggcccagaagactaaagcttcac
tataacgtgactacaactagattagtgaatccagatcaactgttgaatgaaataatgtct
attcttccaaagaagcatgttgactttgtacaaaagggttatacactgaagtgtcaaaca
cagtcagattttgggaaagtgacaatgcaatttgaattagaagtgtgccagcttcaaaaa
cccgatgtggtgggtatcaggaggcagcggcttaagggcgatgcctgggtttacaaaaga
ttagtggaagacatcctatctagctgcaaggtataa

  All links  
Disease (1)   
   OMIM (1)   
Gene (17)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (97)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (95)   
DNA sequence (136)   
   RefSeq(nuc) (96)   
   GenBank (20)   
   EMBL (20)   
3D Structure (32)   
   PDB (32)   
Protein domain (9)   
   Pfam (9)   
All databases (292)   

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