KEGG   Homo sapiens (human): 9868
Entry
9868              CDS       T01001                                 
Symbol
TOMM70, TOMM70A, Tom70
Name
(RefSeq) translocase of outer mitochondrial membrane 70
  KO
K17768  mitochondrial import receptor subunit TOM70
Organism
hsa  Homo sapiens (human)
Network
nt06421  Mitophagy
nt06464  Amyotrophic lateral sclerosis
  Element
N01137  PINK-Parkin-mediated autophagosome formation
N01138  Mutation-inactivated OPTN to PINK-Parkin-mediated autophagosome formation
N01139  Mutation-inactivated p62 to PINK-Parkin-mediated autophagosome formation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:hsa03029]
    9868 (TOMM70)
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    9868 (TOMM70)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial protein import machinery
  Outer membrane
   Transporter outer membrane (TOM) complex
    9868 (TOMM70)
Transporters [BR:hsa02000]
 Other transporters
  Primary active transporters [TC:3]
   9868 (TOMM70)
SSDB
Motif
Pfam: TPR_1 TPR_2 TPR_8 TPR_11 TPR_14 TPR_12 TPR_17 TPR_9 TPR_19 TPR_16 TPR_7 DUF5569 MIT TPR_21 TPR_MalT RPN7 NRBF2_MIT YfiO
Other DBs
NCBI-GeneID: 9868
NCBI-ProteinID: NP_055635
OMIM: 606081
HGNC: 11985
Ensembl: ENSG00000154174
Pharos: O94826(Tbio)
UniProt: O94826
Structure
Position
3:complement(100363431..100401089)
AA seq 608 aa
MAASKPVEAAVVAAAVPSSGSGVGGGGTAGPGTGGLPRWQLALAVGAPLLLGAGAIYLWS
RQQRRREARGRGDASGLKRNSERKTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNK
GNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAV
ELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKA
KEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLK
AKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKE
ANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEA
VADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYA
LYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEI
DNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKK
YGLKPPTL
NT seq 1827 nt   +upstreamnt  +downstreamnt
atggccgcctctaaacctgtggaggcagcggtggtcgcagccgctgtaccgagctccggg
agtggggtgggcggcggcgggactgcgggcccgggcacgggggggctgccgcgatggcag
ctggctctggcggtcggggcacccctgctgctgggcgcgggtgccatatacctgtggagt
cggcagcaacggcgccgggaggccagaggccggggcgacgccagcggcctgaagcgcaac
agcgaacggaagaccccggagggcagggccagtccggccccgggcagcggacaccctgaa
ggtcccggtgctcacttggacatgaactctcttgatagagcccaagcagccaagaataaa
ggcaataaatattttaaagcaggaaaatatgaacaagctattcagtgctatactgaggct
attagcttgtgccctacagagaagaatgttgacctttctacattttatcaaaacagagct
gctgcctttgaacagttgcaaaaatggaaagaagtggcacaagactgtacaaaagctgtt
gaacttaatcccaaatatgtgaaagctctctttagacgtgcaaaagcccatgagaagcta
gacaataagaaggaatgtttagaagatgtcactgctgtgtgtatattagaagggttccaa
aatcaacaaagcatgctgttagccgataaagttcttaaactccttggaaaagagaaagcc
aaagaaaaatataagaatcgtgaacctctgatgccatctccacagtttatcaaatcttac
ttcagttctttcacggatgatatcatttcccagcccatgcttaaaggagagaaatctgat
gaagataaagacaaggaaggggaggctttagaagtgaaagaaaattctggatacttaaag
gccaaacagtatatggaagaagaaaactacgataaaatcataagtgaatgctcaaaagaa
atagatgctgaaggcaaatacatggcagaagcattgctactacgagctaccttctacctg
cttattggcaatgccaatgcagccaaaccagatttagataaagtcatcagtttgaaagaa
gctaatgtgaagcttcgagcaaatgctctcatcaaaagaggcagcatgtacatgcaacag
cagcagcctttgctgtccactcaagattttaacatggctgctgacatcgatcctcagaat
gcagatgtttatcaccaccgaggacagctgaaaatactccttgatcaagttgaagaagca
gtggcagattttgatgaatgtattaggttaagacctgagtctgctctggcacaagcacag
aaatgttttgcattgtaccgccaggcatatacgggaaacaactcttcacaaatccaagca
gctatgaaaggttttgaagaggtcataaagaaatttccaaggtgtgccgaaggctatgca
ctatacgcccaggcattaacagatcaacaacagtttggtaaagctgatgaaatgtatgat
aaatgtattgatttggaaccagataatgctacaacatatgttcataaaggtttacttcaa
cttcagtggaagcaagatctggatagaggtttggaacttatcagcaaggctattgaaatt
gacaataaatgtgattttgcctatgaaaccatgggaactattgaagtacaaagaggaaac
atggagaaagccattgacatgttcaacaaagctattaacctggccaaatcggaaatggag
atggcccatctgtattcactttgcgatgccgcccatgcccagacagaagttgcaaagaaa
tacggattaaaaccaccaacattataa

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Ontology (3)   
   KEGG BRITE (3)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
3D Structure (2)   
   PDB (2)   
Protein domain (18)   
   Pfam (18)   
All databases (73)   

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