KEGG   Homo sapiens (human): 9870
Entry
9870              CDS       T01001                                 
Symbol
AREL1, FIEL1, KIAA0317
Name
(RefSeq) apoptosis resistant E3 ubiquitin protein ligase 1
  KO
K22370  apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    9870 (AREL1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     9870 (AREL1)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  HECT type E3
   9870 (AREL1)
SSDB
Motif
Pfam: HECT Filamin
Other DBs
NCBI-GeneID: 9870
NCBI-ProteinID: NP_001034568
OMIM: 615380
HGNC: 20363
Ensembl: ENSG00000119682
UniProt: O15033
Structure
Position
14:complement(74661256..74713080)
AA seq 823 aa
MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSC
KVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQE
PNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLT
CGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQT
FQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAY
LYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPK
QFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNI
LAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATR
NFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPN
PNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFET
DDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYL
NLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAV
VVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPT
HSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML
NT seq 2472 nt   +upstreamnt  +downstreamnt
atgttttacgttattggtggaatcacagtgtctgtggttgcattcttcttcacaattaag
ttcctctttgagcttgccgcacgtgtagtcagcttcctccagaatgaggaccgcgagcgc
cgaggggaccggactatttatgactacgtgcggggaaattacctggatccccggtcttgc
aaagtctcctgggattggaaggacccctatgaggtgggccacagcatggccttccgagtg
catttattctataagaacgggcagcctttccctgcacatcggcctgtgggactaagagtt
cacatctctcatgtcgagctagcagtggaaattccagtgacccaggaagtccttcaggag
cccaattccaacgtagtaaaagtggccttcactgtgcgcaaggctgggcgttatgaaatc
acagtgaagcttggtggattaaatgtggcatatagtccctactacaaaatttttcaacct
ggaatggtggttccttctaagaccaaaattgtgtgccacttttctactcttgtattgacc
tgtgggcagccgcacacccttcaaatagtaccccgagatgagtatgataatcccaccaac
aattccatgtccttgagagatgagcacaattacaccttgtccattcatgagctcggccct
caagaagaagagagtactggtgtctcatttgagaaatcagtaacatccaacaggcagact
ttccaggtgttcttgcgactcaccctgcattctcgaggctgcttccatgcttgcatttca
taccaaaatcagccaatcaataatggtgaatttgacattattgtcctaagtgaggatgag
aagaatatcgtcgaacgcaatgtgtccacttcaggcgtgagcatttactttgaggcttat
ctttataatgctaccaactgtagcagcactccatggcacctgccacccatgcacatgacc
tcttcccagcgccggccatccactgctgttgacgaggaagatgaagactcgccctctgag
tgccacacccctgagaaggtgaagaaaccgaagaaggtgtactgctatgtgtcaccaaag
caattctcagtgaaggagttctacctgaagatcatcccctggcgcctttacaccttccga
gtgtgtccaggaacaaaattttcataccttggtcctgaccctgtccataagctgctcaca
ctggtggtggatgatggcattcaacctcctgtggagctcagctgtaaggagaggaacatt
ctagcagccacttttatccgctccctgcataagaacataggaggctctgagacctttcag
gacaaggtgaactttttccagcgagagcttcggcaggtacatatgaaaagaccacattcc
aaagtcaccctgaaggtcagcagacatgccttgttggaatcgtctctgaaagccactcgg
aatttctccatctcagattggagcaagaactttgaggttgttttccaggatgaagaagct
ctggactggggagggcctcgccgggaatggtttgagctaatctgcaaagcactatttgat
accaccaatcagctcttcacccggttcagtgacaacaaccaagcattagtgcatcccaac
cctaatcgccccgctcatctgcgcctgaaaatgtatgagtttgcgggacggctcgtgggc
aagtgtctctatgagtcctctctaggaggagcctacaagcagttggtccgagctcgcttc
acccgctctttcctggcccaaatcataggactgcgtatgcattacaagtactttgaaaca
gatgacccagaattctacaaatctaaagtttgttttatcctcaacaatgacatgagtgag
atggagctggtctttgcagaagagaaatataataaatcaggtcaattggataaggttgta
gaactcatgacaggtggagctcaaactccagtcaccaatgcgaataaaatcttctattta
aatttgctggcccaatatcggctggccagtcaagtgaaagaggaggtggaacatttccta
aaaggcctgaatgaattggtccctgagaaccttttggctatttttgatgagaatgagctt
gagctgctgatgtgtgggactggagacatcagtgtgtctgacttcaaagcccatgcagta
gttgttggtggctcatggcatttcagagaaaaggtcatgaggtggttttggactgtggtt
tccagtctgacccaggaggagttggctcggctacttcagttcacaacaggctcctctcag
ctaccacctggaggctttgccgccctctgtccctcatttcagattattgccgctccgacc
catagcacgctgcctactgcacacacatgttttaaccagctgtgcctccctacatatgac
tcctatgaagaggtgcacaggatgctgcagctggccatcagcgagggttgcgagggcttt
ggcatgctctga

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Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
Protein sequence (18)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (16)   
DNA sequence (29)   
   RefSeq(nuc) (17)   
   GenBank (6)   
   EMBL (6)   
3D Structure (2)   
   PDB (2)   
Protein domain (2)   
   Pfam (2)   
All databases (76)   

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