KEGG   Homo sapiens (human): 9894
Entry
9894              CDS       T01001                                 
Symbol
TELO2, CLK2, TEL2, YHFS
Name
(RefSeq) telomere maintenance 2
  KO
K11137  telomere length regulation protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa03460  Fanconi anemia pathway
hsa04150  mTOR signaling pathway
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06461  Huntington disease
nt06462  Spinocerebellar ataxia
nt06466  Pathways of neurodegeneration
nt06522  mTOR signaling
nt06532  Autophagy
  Element
N00155  Autophagy-vesicle nucleation/elongation/maturation, mTORC1-PI3KC3-C1
N01575  TSC1/2-mTORC1 signaling pathway
N01578  GATOR1-mTORC1 signaling pathway
N01584  FLCN-mTORC1 signaling pathway
Disease
H01789  You-Hoover-Fong syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03460 Fanconi anemia pathway
    9894 (TELO2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    9894 (TELO2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    9894 (TELO2)
   03036 Chromosome and associated proteins [BR:hsa03036]
    9894 (TELO2)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    9894 (TELO2)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Termination Factors
   Other termination factors
    9894 (TELO2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Chromatin remodeling factors
   ASTRA complex
    9894 (TELO2)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   FA (Fanconi anemia) pathway
    Other FA pathway factors
     9894 (TELO2)
  Check point factors
   Triple T complex
    9894 (TELO2)
SSDB
Motif
Pfam: Telomere_reg-2
Other DBs
NCBI-GeneID: 9894
NCBI-ProteinID: NP_057195
OMIM: 611140
HGNC: 29099
Ensembl: ENSG00000100726
UniProt: Q9Y4R8 B4DXS2
Structure
Position
16:1493360..1510454
AA seq 837 aa
MEPAPSEVRLAVREAIHALSSSEDGGHIFCTLESLKRYLGEMEPPALPREKEEFASAHFS
PVLRCLASRLSPAWLELLPHGRLEELWASFFLEGPADQAFLVLMETIEGAAGPSFRLMKM
ARLLARFLREGRLAVLMEAQCRQQTQPGFILLRETLLGKVVALPDHLGNRLQQENLAEFF
PQNYFRLLGEEVVRVLQAVVDSLQGGLDSSVSFVSQVLGKACVHGRQQEILGVLVPRLAA
LTQGSYLHQRVCWRLVEQVPDRAMEAVLTGLVEAALGPEVLSRLLGNLVVKNKKAQFVMT
QKLLFLQSRLTTPMLQSLLGHLAMDSQRRPLLLQVLKELLETWGSSSAIRHTPLPQQRHV
SKAVLICLAQLGEPELRDSRDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVVSARIHPE
GPPLKFQYEEDELSLELLALASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDGGVPQA
QLAGSDSDLDSDDEFVPYDMSGDRELKSSKAPAYVRDCVEALTTSEDIERWEAALRALEG
LVYRSPTATREVSVELAKVLLHLEEKTCVVGFAGLRQRALVAVTVTDPAPVADYLTSQFY
ALNYSLRQRMDILDVLTLAAQELSRPGCLGRTPQPGSPSPNTPCLPEAAVSQPGSAVASD
WRVVVEERIRSKTQRLSKGGPRQGPAGSPSRFNSVAGHFFFPLLQRFDRPLVTFDLLGED
QLVLGRLAHTLGALMCLAVNTTVAVAMGKALLEFVWALRFHIDAYVRQGLLSAVSSVLLS
LPAARLLEDLMDELLEARSWLADVAEKDPDEDCRTLALRALLLLQRLKNRLLPPASP
NT seq 2514 nt   +upstreamnt  +downstreamnt
atggagccagcaccctcagaggttcgactcgccgtccgggaagccattcatgccctctcg
tcttcggaggatggcggccacatcttctgcaccctggagtccctgaagcggtatctcggt
gagatggagcctccagcgctcccgagggagaaggaggagtttgcctcggcccacttctcg
cctgtcctcagatgtcttgccagcaggctgagcccagcctggctggagctgctgccccat
ggccgcctggaggagctgtgggccagcttcttcctggagggcccggcggaccaagccttc
ctggtgttgatggagaccatcgagggtgctgcgggccccagcttccggctgatgaagatg
gcgcggctgctggccagattcctgcgcgagggccggctggcagtgctgatggaggcgcag
tgtcggcagcagacgcagcccggcttcatcctgctccgggagacgctgctgggcaaggtg
gtggccctgcccgatcacctgggcaaccgcctgcagcaggagaacttggccgagttcttc
ccccagaactacttccgcctgctcggcgaggaggtcgtccgggtgctgcaggcggttgtg
gactctctccaaggtggcctggattcctccgtgtccttcgtgtctcaggtccttgggaaa
gcctgtgtccacgggaggcagcaggagatcctgggcgtgctggtaccccggctggcagcg
ctcacccagggcagctacctgcaccagcgcgtctgctggcgcctggtggagcaagtgccg
gaccgggccatggaggctgtgctgaccgggctggtggaggccgcactggggcctgaggtc
ctttcgagactgctggggaacctggtggtgaagaacaagaaggcccagtttgtgatgacc
cagaagcttctgttcttacagtcccggctcacgacgcccatgctgcagagcctgctgggc
catctggccatggacagccagcggcgcccgctcctgctgcaggtgctgaaggagctgttg
gagacgtggggcagcagcagtgccatccgccacactcccctgccgcagcagcgccacgtc
agcaaggctgtcctcatctgcctggcgcaactcggggagccggaactgcgggacagccgg
gatgaactgctggccagcatgatggcgggcgtgaagtgccgcctggacagtagcctgccc
cccgtgcgacgcctgggcatgatcgtggcagaggtcgttagtgcccggatccaccccgag
gggcctcccctgaaattccagtacgaagaggatgaactgagcctcgagctgctggccttg
gcctccccccagcctgcgggtgacggcgcctcggaggcgggcacgtccctcgttccagcc
acggcagagccccctgcagagacccccgcagagatcgtggatggcggcgtcccccaagca
cagctggcgggctctgactcggacctggacagcgatgatgagtttgtcccctacgacatg
tcgggggacagagagctgaagagcagcaaggctcctgcctacgtccgggactgcgtggaa
gccctgaccacgtctgaggacatagagcgctgggaggcagccctgcgggcccttgagggc
ctggtctacaggagccccacagccactcgggaggtgagcgtggagctggccaaggtgctt
ctgcatctggaggagaagacctgtgtggtgggatttgcagggctgcgccagagagccctg
gtggccgtcacggtcacagacccggccccggtggccgactatctgacctcacagttctat
gccctcaactacagcctccggcagcgcatggacatcctggatgtgctgactctggctgcc
caggagctgtctaggcctgggtgcctcgggaggactccccaacctggctccccaagtccc
aacaccccgtgcctgccagaggcagccgtctctcagcctggcagtgccgtggcgtctgac
tggcgggtggtggtggaggagcggatcagaagcaagacccagcggctctccaagggtggc
ccgaggcagggcccggcaggcagccccagcagattcaactccgtggccggccacttcttc
ttccccctccttcagcgctttgacaggcctctggtgaccttcgacctcttgggagaagac
cagctggttctcggaaggctggcgcacaccttaggggccctgatgtgcctggctgttaac
accacggtggctgtggccatgggcaaggccctgctggaattcgtgtgggcccttcgcttc
cacatcgatgcctacgtgcgccaggggctgttgtcggccgtctcctccgtcctgctcagc
ctgcctgctgcgcgcctgctggaggacctgatggacgagctgctggaagcccggtcctgg
ctggcggacgtggctgagaaagacccggacgaggactgcaggacgctggcactgagggcc
ctgctgcttctgcagagactcaagaacaggctcctcccacccgcgtctccctag

  All links  
Disease (2)   
   OMIM (2)   
Gene (35)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (18)   
   OC (1)   
Protein sequence (31)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (28)   
DNA sequence (48)   
   RefSeq(nuc) (28)   
   GenBank (10)   
   EMBL (10)   
3D Structure (3)   
   PDB (3)   
Protein domain (1)   
   Pfam (1)   
All databases (120)   

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