KEGG   Homo sapiens (human): 9899
Entry
9899              CDS       T01001                                 
Symbol
SV2B, HsT19680, SLC22B2
Name
(RefSeq) synaptic vesicle glycoprotein 2B
  KO
K06258  MFS transporter, VNT family, synaptic vesicle glycoprotein 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04512  ECM-receptor interaction
Drug target
Padsevonil: D11842
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    9899 (SV2B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    9899 (SV2B)
Transporters [BR:hsa02000]
 Major facilitator superfamily (MFS)
  Protein transporters
   Vesicular neurotransmitter transporter (VNT) [TC:2.A.1.22]
    9899 (SV2B)
SSDB
Motif
Pfam: LD_SV2 MFS_1 Sugar_tr Pentapeptide_4 Pentapeptide_3
Other DBs
NCBI-GeneID: 9899
NCBI-ProteinID: NP_001309960
OMIM: 185861
HGNC: 16874
Ensembl: ENSG00000185518
UniProt: Q7L1I2
Structure
Position
15:91099588..91302565
AA seq 683 aa
MDDYKYQDNYGGYAPSDGYYRGNESNPEEDAQSDVTEGHDEEDEIYEGEYQGIPHPDDVK
AKQAKMAPSRMDSLRGQTDLMAERLEDEEQLAHQYETIMDECGHGRFQWILFFVLGLALM
ADGVEVFVVSFALPSAEKDMCLSSSKKGMLGMIVYLGMMAGAFILGGLADKLGRKRVLSM
SLAVNASFASLSSFVQGYGAFLFCRLISGIGIGGALPIVFAYFSEFLSREKRGEHLSWLG
IFWMTGGLYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSMVALKFMPES
PRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSNIKTPKQMDEFIEIQSSTGTWY
QRWLVRFKTIFKQVWDNALYCVMGPYRMNTLILAVVWFAMAFSYYGLTVWFPDMIRYFQD
EEYKSKMKVFFGEHVYGATINFTMENQIHQHGKLVNDKFTRMYFKHVLFEDTFFDECYFE
DVTSTDTYFKNCTIESTIFYNTDLYEHKFINCRFINSTFLEQKEGCHMDLEQDNDFLIYL
VSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFFGNSESAMIGWQCLFC
GTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFVGITKVVPILLA
AASLVGGGLIALRLPETREQVLM
NT seq 2052 nt   +upstreamnt  +downstreamnt
atggatgactacaagtatcaggacaattatgggggctatgctcccagtgatggctattac
cgcggcaatgagtccaacccagaagaagatgcacagagtgatgtcaccgaaggccatgat
gaggaagacgagatctatgagggcgagtaccagggtatccctcacccagatgatgtcaag
gccaagcaggccaagatggcgccctccagaatggacagccttcggggccagacagacctg
atggctgagaggctggaagatgaggagcagttggcccaccagtacgagaccatcatggat
gagtgtggccatggccgcttccagtggatcctctttttcgtcttgggtttggccctgatg
gccgatggggtggaagtgttcgtggtgagttttgccctgcccagtgcagagaaggacatg
tgtctgtccagttccaaaaaaggaatgctagggatgatagtctacttgggaatgatggcg
ggcgccttcatcctgggaggcctggctgataagctgggaaggaagcgagtcctcagcatg
tctctggccgtcaatgcctccttcgcctccctctcttccttcgtgcagggatatggagcc
ttcctcttctgccgactcatctcaggcatcggtattgggggtgctctaccgattgttttt
gcctatttttctgaattcttgtctcgggagaagcgaggagaacacctcagttggctgggc
atcttctggatgactgggggcctgtacgcatctgccatggcctggagcatcatcccacac
tatggctggggcttcagcatggggaccaattaccacttccatagctggagagtgtttgtc
atcgtctgtgctctgccctgcaccgtgtccatggtggccctgaagttcatgccagagagc
ccaaggtttctgctagagatgggcaaacatgatgaagcctggatgattctcaagcaagtc
catgacaccaacatgagagctaaggggaccccagagaaagtgttcacggtttccaacatc
aaaactcccaagcaaatggatgaattcattgagatccaaagttcaacaggaacctggtac
cagcgctggctggtcagattcaagaccattttcaagcaggtctgggataatgccctgtac
tgtgtgatggggccctacagaatgaatacactgattctggccgtggtttggtttgccatg
gcattcagttactatggactgacagtttggtttcctgatatgatccgctattttcaagat
gaagaatacaagtctaaaatgaaggtgttttttggtgagcatgtgtacggcgccacaatc
aacttcacgatggaaaatcagatccaccaacatgggaaacttgtgaatgataagttcaca
agaatgtactttaaacatgtactctttgaggacacattctttgacgagtgctattttgaa
gacgtaacatcaacagatacctacttcaaaaattgtaccattgaatcaaccatcttttac
aacacagacctctacgagcacaagttcatcaactgtcggtttatcaactccaccttcctg
gagcagaaggagggctgccacatggacttggagcaagataatgacttcctgatttacctc
gtcagcttcctgggcagcctgtctgtcttacccgggaacatcatttctgccctgctcatg
gatagaattggaaggctcaagatgattggtggctccatgctaatctctgcagtctgctgc
ttcttcctgttttttggcaacagtgagtctgcaatgatcggctggcagtgcctgttctgt
gggacaagcattgcagcctggaatgctctggatgtgatcacagtggagctgtatcccacc
aaccagagagcaacagccttcggcattctcaatggattatgcaaatttggcgccatcctg
ggaaacaccatctttgcttcttttgttgggataaccaaagtggtccccatccttctggct
gctgcttctctggttgggggtggcctgattgcccttcgactgccagagactcgagaacag
gtcctgatgtga

  All links  
Disease (1)   
   OMIM (1)   
Gene (10)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (22)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (20)   
DNA sequence (46)   
   RefSeq(nuc) (20)   
   GenBank (13)   
   EMBL (13)   
3D Structure (6)   
   PDB (6)   
Protein domain (5)   
   Pfam (5)   
All databases (90)   

Download RDF
DBGET integrated database retrieval system