KEGG   Homo sapiens (human): 994Help
Entry
994               CDS       T01001                                 

Gene name
CDC25B
Definition
(RefSeq) cell division cycle 25B
  KO
K05866  M-phase inducer phosphatase 2 [EC:3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04110  Cell cycle
hsa04914  Progesterone-mediated oocyte maturation
hsa05206  MicroRNAs in cancer
Module
hsa_M00691  DNA damage-induced cell cycle checkpoints
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    994 (CDC25B)
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    994 (CDC25B)
 Organismal Systems
  Endocrine system
   04914 Progesterone-mediated oocyte maturation
    994 (CDC25B)
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    994 (CDC25B)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     994 (CDC25B)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Tyrosine phosphatases (PTPs)
  Class III PTPs
   CDC25s
    994 (CDC25B)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic Type
  Check point factors
   Other check point factors
    994 (CDC25B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: M-inducer_phosp Rhodanese
Motif
Other DBs
NCBI-GeneID: 994
NCBI-ProteinID: NP_068659
OMIM: 116949
HGNC: 1726
Ensembl: ENSG00000101224
Vega: OTTHUMG00000031764
Pharos: P30305(Tchem)
UniProt: P30305 B3KS38 Q6MZW8
Structure
PDB: 

Position
20p13
AA seq 580 aa AA seqDB search
MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMH
DLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMD
PHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEA
GSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPD
RKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKT
LEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQ
QEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETM
VALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKR
VILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQ
DYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
NT seq 1743 nt NT seq  +upstreamnt  +downstreamnt
atggaggtgccccagccggagcccgcgccaggctcggctctcagtccagcaggcgtgtgc
ggtggcgcccagcgtccgggccacctcccgggcctcctgctgggatctcatggcctcctg
gggtccccggtgcgggcggccgcttcctcgccggtcaccaccctcacccagaccatgcac
gacctcgccgggctcggcagcgaaaccccaaagagtcaggtagggaccctgctcttccgc
agccgcagccgcctgacgcacctatccctgtctcgacgggcatccgaatcctccctgtcg
tctgaatcctccgaatcttctgatgcaggtctctgcatggattcccccagccctatggac
ccccacatggcggagcagacgtttgaacaggccatccaggcagccagccggatcattcga
aacgagcagtttgccatcagacgcttccagtctatgccggtgaggctgctgggccacagc
cccgtgcttcggaacatcaccaactcccaggcgcccgacggccggaggaagagcgaggcg
ggcagtggagctgccagcagctctggggaagacaaggagaatgatggatttgtcttcaag
atgccatggaagcccacacatcccagctccacccatgctctggcagagtgggccagccgc
agggaagcctttgcccagagacccagctcggcccccgacctgatgtgtctcagtcctgac
cggaagatggaagtggaggagctcagccccctggccctaggtcgcttctctctgacccct
gcagagggggatactgaggaagatgatggatttgtggacatcctagagagtgacttaaag
gatgatgatgcagttcccccaggcatggagagtctcattagtgccccactggtcaagacc
ttggaaaaggaagaggaaaaggacctcgtcatgtacagcaagtgccagcggctcttccgc
tctccgtccatgccctgcagcgtgatccggcccatcctcaagaggctggagcggccccag
gacagggacacgcccgtgcagaataagcggaggcggagcgtgacccctcctgaggagcag
caggaggctgaggaacctaaagcccgcgtcctccgctcaaaatcactgtgtcacgatgag
atcgagaacctcctggacagtgaccaccgagagctgattggagattactctaaggccttc
ctcctacagacagtagacggaaagcaccaagacctcaagtacatctcaccagaaacgatg
gtggccctattgacgggcaagttcagcaacatcgtggataagtttgtgattgtagactgc
agatacccctatgaatatgaaggcgggcacatcaagactgcggtgaacttgcccctggaa
cgcgacgccgagagcttcctactgaagagccccatcgcgccctgtagcctggacaagaga
gtcatcctcattttccactgtgaattctcatctgagcgtgggccccgcatgtgccgtttc
atcagggaacgagaccgtgctgtcaacgactaccccagcctctactaccctgagatgtat
atcctgaaaggcggctacaaggagttcttccctcagcacccgaacttctgtgaaccccag
gactaccggcccatgaaccacgaggccttcaaggatgagctaaagaccttccgcctcaag
actcgcagctgggctggggagcggagccggcgggagctctgtagccggctgcaggaccag
tga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (10)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (14)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (55)   
   RefSeq(nuc) (15)   
   GenBank (20)   
   EMBL (20)   
Protein domain (2)   
   Pfam (2)   
All databases (111)   

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