KEGG   Homo sapiens (human): 995
Entry
995               CDS       T01001                                 

Gene name
CDC25C, CDC25, PPP1R60
Definition
(RefSeq) cell division cycle 25C
  KO
K05867  M-phase inducer phosphatase 3 [EC:3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa04114  Oocyte meiosis
hsa04914  Progesterone-mediated oocyte maturation
hsa05170  Human immunodeficiency virus 1 infection
hsa05206  MicroRNAs in cancer
Network
nt06130  Cell cycle (viruses)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
  Element
N00455  CDC25-Cell cycle G2/M
N00456  HIV Vpr to CDC25-cell cycle G2M
N00458  HIV Vpr to CDC25-cell cycle G2M
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    995 (CDC25C)
   04114 Oocyte meiosis
    995 (CDC25C)
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    995 (CDC25C)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    995 (CDC25C)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    995 (CDC25C)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    995 (CDC25C)
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    995 (CDC25C)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     995 (CDC25C)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     995 (CDC25C)
 Protein tyrosine phosphatases (PTPs)
  Class III PTPs
   CDC25s
    995 (CDC25C)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    995 (CDC25C)
SSDB
Motif
Pfam: Rhodanese M-inducer_phosp
Other DBs
NCBI-GeneID: 995
NCBI-ProteinID: NP_001274511
OMIM: 157680
HGNC: 1727
Ensembl: ENSG00000158402
Vega: OTTHUMG00000129203
Pharos: P30307(Tchem)
UniProt: P30307
Structure
PDB: 
5M37 5M36 3OP3

Position
5q31.2
AA seq 473 aa
MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL
SILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMK
CSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNP
NLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDK
VKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQ
DLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKK
PIVPLDTQKRIIIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFF
PEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP
NT seq 1422 nt   +upstreamnt  +downstreamnt
atgtctacggaactcttctcatccacaagagaggaaggaagctctggctcaggacccagt
tttaggtctaatcaaaggaaaatgttaaacctgctcctggagagagacacttcctttacc
gtctgtccagatgtccctagaactccagtgggcaaatttcttggtgattctgcaaaccta
agcattttgtctggaggaaccccaaaacgttgcctcgatctttcgaatcttagcagtggg
gagataactgccactcagcttaccacttctgcagaccttgatgaaactggtcacctggat
tcttcaggacttcaggaagtgcatttagctgggatgaatcatgaccagcacctaatgaaa
tgtagcccagcacagcttctttgtagcactccgaatggtttggaccgtggccatagaaag
agagatgcaatgtgtagttcatctgcaaataaagaaaatgacaatggaaacttggtggac
agtgaaatgaaatatttgggcagtcccattactactgttccaaaattggataaaaatcca
aacctaggagaagaccaggcagaagagatttcagatgaattaatggagttttccctgaaa
gatcaagaagcaaaggtgagcagaagtggcctatatcgctccccgtcgatgccagagaac
ttgaacaggccaagactgaagcaggtggaaaaattcaaggacaacacaataccagataaa
gttaaaaaaaagtatttttctggccaaggaaagctcaggaagggcttatgtttaaagaag
acagtctctctgtgtgacattactatcactcagatgctggaggaagattctaaccagggg
cacctgattggtgatttttccaaggtatgtgcgctgccaaccgtgtcagggaaacaccaa
gatctgaagtatgtcaacccagaaacagtggctgccttactgtcggggaagttccagggt
ctgattgagaagttttatgtcattgattgtcgctatccatatgagtatctgggaggacac
atccagggagccttaaacttatatagtcaggaagaactgtttaacttctttctgaagaag
cccatcgtccctttggacacccagaagagaataatcatcgtgttccactgtgaattctcc
tcagagaggggcccccgaatgtgccgctgtctgcgtgaagaggacaggtctctgaaccag
tatcctgcattgtactacccagagctatatatccttaaaggcggctacagagacttcttt
ccagaatatatggaactgtgtgaaccacagagctactgccctatgcatcatcaggaccac
aagactgagttgctgaggtgtcgaagccagagcaaagtgcaggaaggggagcggcagctg
cgggagcagattgcccttctggtgaaggacatgagcccatga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (5)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (18)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (16)   
DNA sequence (50)   
   RefSeq(nuc) (16)   
   GenBank (17)   
   EMBL (17)   
Protein domain (2)   
   Pfam (2)   
All databases (106)   

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