KEGG   MODULE: hsa_M00049Help
Entry
hsa_M00049        Pathway   Module                                 

Name
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
Definition
K01939 K01756 (K00939,K18532,K18533,K00944) (K00940,K00873,K12406)
Module map
hsa_M00049

Orthology
K01939  
adenylosuccinate synthase [EC:6.3.4.4] [RN:R01135]
K01756  
adenylosuccinate lyase [EC:4.3.2.2] [RN:R01083]
adenylate kinase [EC:2.7.4.3] [RN:R00127]
K00944  
nucleoside-triphosphate--adenylate kinase [EC:2.7.4.10] [RN:R00333]
K00940  
nucleoside-diphosphate kinase [EC:2.7.4.6] [RN:R00124]
pyruvate kinase [EC:2.7.1.40] [RN:R00200]
Ortholog tableTaxonomy
Class
Pathway module; Nucleotide and amino acid metabolism; Purine metabolism
BRITE hierarchy
Pathway
hsa00230  Purine metabolism
hsa01100  Metabolic pathways
Organism
Homo sapiens (human) [GN:hsa]
Gene
10201  NME6; NME/NM23 nucleoside diphosphate kinase 6 [KO:K00940]
102157402  AK6; adenylate kinase 6 [KO:K18532]
122481  AK7; adenylate kinase 7 [KO:K00939]
122622  ADSSL1; adenylosuccinate synthase like 1 [KO:K01939]
158  ADSL; adenylosuccinate lyase [KO:K01756]
158067  AK8; adenylate kinase 8 [KO:K00939]
159  ADSS; adenylosuccinate synthase [KO:K01939]
203  AK1; adenylate kinase 1 [KO:K00939]
204  AK2; adenylate kinase 2 [KO:K00939]
205  AK4; adenylate kinase 4 [KO:K00939]
221264  AK9; adenylate kinase 9 [KO:K18533]
26289  AK5; adenylate kinase 5 [KO:K00939]
29922  NME7; NME/NM23 family member 7 [KO:K00940]
390877  adenylate kinase isoenzyme 1-like [KO:K00939]
4830  NME1; NME/NM23 nucleoside diphosphate kinase 1 [KO:K00940]
4831  NME2; NME/NM23 nucleoside diphosphate kinase 2 [KO:K00940]
4832  NME3; NME/NM23 nucleoside diphosphate kinase 3 [KO:K00940]
4833  NME4; NME/NM23 nucleoside diphosphate kinase 4 [KO:K00940]
50808  AK3; adenylate kinase 3 [KO:K00944]
5313  PKLR; pyruvate kinase L/R [KO:K12406]
5315  PKM; pyruvate kinase M1/2 [KO:K00873]
654364  NME1-NME2; NME1-NME2 readthrough [KO:K00940]
Reaction
Compound
C00130  IMP
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C00020  AMP
C00008  ADP
C00002  ATP
Other DBs
BSID: 618580
KO module

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