KEGG   VARIANT: 1630v1Help
Entry
1630v1                      Variant                                

Name
DCC loss
Gene
DCC  DCC netrin 1 receptor [KO:K06765]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
Allelic loss on 18q21.3
Network
nt06231  Apoptosis
nt06260  Colorectal cancer
  Element
N00102  Loss of DCC to DCC-apoptotic pathway
Reference
  Authors
Houlston RS.
  Title
What we could do now: molecular pathology of colorectal cancer.
  Journal
Mol Pathol 54:206-14 (2001)
DOI:10.1136/mp.54.4.206
Reference
  Authors
Ko SY, Dass CR, Nurgali K
  Title
Netrin-1 in the developing enteric nervous system and colorectal cancer.
  Journal
Trends Mol Med 18:544-54 (2012)
DOI:10.1016/j.molmed.2012.07.001
Reference
  Authors
Mehlen P, Llambi F
  Title
Role of netrin-1 and netrin-1 dependence receptors in colorectal cancers.
  Journal
Br J Cancer 93:1-6 (2005)
DOI:10.1038/sj.bjc.6602656
Reference
  Authors
Arakawa H.
  Title
Netrin-1 and its receptors in tumorigenesis.
  Journal
Nat Rev Cancer 4:978-87 (2004)
DOI:10.1038/nrc1504

DBGET integrated database retrieval system