KEGG   Jannaschia sp. CCS1: Jann_1959
Entry
Jann_1959         CDS       T00330                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
jan  Jannaschia sp. CCS1
Pathway
jan00290  Valine, leucine and isoleucine biosynthesis
jan00620  Pyruvate metabolism
jan01100  Metabolic pathways
jan01110  Biosynthesis of secondary metabolites
jan01210  2-Oxocarboxylic acid metabolism
jan01230  Biosynthesis of amino acids
Module
jan_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:jan00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    Jann_1959
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    Jann_1959
Enzymes [BR:jan01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     Jann_1959
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: ABD54876
UniProt: Q28QY6
Position
1952908..1954530
AA seq 540 aa
MTKSRLYLYDTTLRDGQQTQGVQFSTPEKVRIAEALDALGLDYIEGGWPGANPTDSAFFD
DAPRTRARMTAFGMTKRAGRSAENDDVLAAVLNAGTGTVCLVGKSHDFHVTEALGITLAE
NVENIRASIAHLVAQGREAIFDAEHFFDGHKANPDYALECIHAAYSAGARWVVLCDTNGG
TLPDEIAGITHAVIASGLPGECLGIHTHNDTETAVAGSLAAVQAGARQIQGTLNGLGERC
GNANLTTLIPTLLLKEPYRSSYDTGIAVETLDGLTRLSRMLDDILNRVPHRQAPYVGASA
FAHKAGLHASAIVKNPTTYEHIAPEIVGNDRIIPMSNQAGQSNLRKRLAEAGLEVERDNP
ALPAILDAIKDREADGYSFDTAQASFELLARRALGMLPAFFEVKRYRVTVERRKNKYNQM
VSLSEAMVVLKVGGEKKLSVSESMDETGSDRGPVNALSKALAKDLGPYQEFIKDIRLVDF
KVRITQGGTEAVTRVIIDSEDSQGRRWSTVGVSPNIVDASFEALLDAVNWKLIHEGAAVL
NT seq 1623 nt   +upstreamnt  +downstreamnt
atgaccaaatcccgcctctatctttacgacaccaccctgcgcgacgggcagcagacccag
ggcgtccagttttccacgcccgagaaggtccgcatcgccgaggcgctcgacgccctcggc
ctcgactatatcgaaggcggctggcccggcgcgaaccccaccgacagcgcgtttttcgac
gatgcccccaggacccgcgcccggatgacggccttcgggatgaccaagcgggccgggcgc
tcggctgagaatgacgacgttctggccgccgtcctgaatgcaggcacagggaccgtctgc
cttgtcggcaagtcccatgattttcacgtgaccgaagcgcttggcatcaccttggcggag
aatgtcgagaatatccgcgcctccatcgcccacctcgtcgcccagggccgcgaggcgatc
tttgacgcggagcatttctttgacggccacaaggccaacccggactatgcgctggaatgc
atccatgccgcctacagcgcaggcgcgcggtgggtggtgctgtgtgacaccaacggcggg
acgttgcctgacgagattgccgggatcacccacgccgtcatcgcctcaggtctccccggg
gaatgtctgggcatccatacgcataacgataccgaaaccgccgtggcgggcagcctcgcg
gcggtgcaggcgggcgcgcgtcagatccagggcacgttgaatggtttgggggagcgctgc
ggcaacgccaatctgaccacgctgatcccgacccttttgctgaaagagccgtaccggtcg
tcctatgacaccgggatcgcggtggagacgttggatggcctgacgcgactgagccggatg
ctggacgatatcctcaaccgggtgccgcaccgacaagcgccctatgtgggggcctcggcc
ttcgcccataaagcgggcctccacgccagcgccatcgtcaagaaccccacgacctacgag
catatcgcgcccgaaatcgtcggcaatgaccgcatcatcccgatgtccaatcaggcgggc
cagtcgaacctgcgcaagcgtctggcggaggcggggttggaggtcgaaagggacaacccg
gcgctgcctgcgatcctcgatgcgatcaaggaccgggaggcggacgggtacagctttgac
acggcccaggcctccttcgagttgctggcgcggcgcgcgttggggatgttgcccgcgttc
tttgaggtcaagcgctaccgcgtcacggtggagcggcggaagaacaagtacaatcagatg
gtgagcctttcggaggcgatggtcgtcctgaaagtgggcggcgaaaagaagctgtcggtc
agcgaaagcatggacgagacgggcagcgaccgggggccggtgaacgcattgtcgaaggct
ctggcgaaggatctggggccgtatcaggaattcatcaaggatatccgccttgtggacttc
aaggtccgcatcacccaaggcggcacagaggccgtcacccgcgtgatcatcgacagcgag
gacagtcaggggcggcgctggtcgaccgtgggcgtatcccccaacatcgtggatgcgagt
ttcgaggcgctgctggacgcggtgaactggaaactgatccacgaaggcgcagcggtccta
tga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (34)   
   KEGG ORTHOLOGY (1)   
   RefGene (31)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (54)   

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