KEGG   Kitasatospora aureofaciens: B6264_18525
Entry
B6264_18525       CDS       T05021                                 
Name
(GenBank) FAD-dependent oxidoreductase
  KO
K14257  tetracycline 7-halogenase / FADH2 O2-dependent halogenase [EC:1.14.19.49 1.14.19.-]
Organism
kau  Kitasatospora aureofaciens
Pathway
kau00253  Tetracycline biosynthesis
kau01057  Biosynthesis of type II polyketide products
kau01100  Metabolic pathways
kau01110  Biosynthesis of secondary metabolites
Module
kau_M00823  Chlortetracycline biosynthesis, pretetramide => chlortetracycline
Brite
KEGG Orthology (KO) [BR:kau00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    B6264_18525
   00253 Tetracycline biosynthesis
    B6264_18525
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    B6264_18525
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:kau01008]
    B6264_18525
Enzymes [BR:kau01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.49  tetracycline 7-halogenase
     B6264_18525
Polyketide biosynthesis proteins [BR:kau01008]
 Polyketide tailoring proteins
  Halogenase
   B6264_18525
SSDB
Motif
Pfam: FAD_binding_3 Trp_halogenase DAO Lycopene_cycl NAD_binding_8 Pyr_redox_2 FAD_binding_2 HI0933_like Pyr_redox_3 Thi4 Pyr_redox HCBP_related FAD_oxidored GDI
Other DBs
NCBI-ProteinID: ARF80633
UniProt: A0A1E7MYN1
Structure
Position
complement(4204797..4206464)
AA seq 555 aa
MTDTTADQTRHGDRPYDVVIIGSGLSGTMLGSILAKHGFRIMLLDGAHHPRFAVGESTIG
QTLVVLRLISDRYGVPEIANLASFQDVLANVSSSHGQKSNFGFMFHRDGEEPDPNETSQF
RIPSIVGNAAHFFRQDTDSYMFHAAVRYGCDARQYYRVENIEFDDGGVTVSGADGSTVRA
RYLVDASGFRSPLARQLGLREEPSRLKHHARSIFTHMVGVDAIDDHVDTPAELRPPVPWN
DGTMHHIFERGWMWIIPFNNHPGATNPLCSVGIQLDERRYPARPDLTPEEEFWSHVDRFP
AVQRQLKGARSVREWVRTDRMQYSSSRTVGERWCLMSHAAGFIDPLFSRGLSNTCEIINA
LSWRLMAALREDDFAVERFAYVEELEQGLLDWNDKLVNNSFISFSHYPLWNSVFRIWASA
SVIGGKRILNALTRTKETGDDSHCQALDDNPYPGLWCPLDFYKEAFDELTELCEAVDAGH
TTAEEAARVLEQRVRESDWMLPALGFNDPDTHHINPTADKMIRIAEWATGHHRPEIRELL
AASAEEVRAAMRVKP
NT seq 1668 nt   +upstreamnt  +downstreamnt
atgaccgacacaaccgcggatcagacgcggcacggcgaccggccgtacgacgtcgtcatc
atcggcagcgggctgtcgggcaccatgctcggctcgatcctcgccaagcacggcttccgg
atcatgctgctggacggtgcccaccacccccgcttcgccgtcggcgagtccaccatcggg
cagacgctggtggtgctgcggctgatctcggaccggtacggggtgccggagatcgccaac
ctggcgagcttccaggacgtcctcgccaacgtcagcagttcgcacgggcagaagagcaac
ttcggcttcatgttccaccgggacggcgaggagccggacccgaacgagaccagccagttc
cgcatcccctcgatcgtcggcaacgcggcccacttcttccgccaggacaccgactcctac
atgttccacgccgcggtgcgctacggctgcgacgcccggcagtactaccgggtggagaac
atcgagttcgacgacggcggggtgaccgtctccggcgcggacggcagcaccgtccgggcc
cgctacctggtcgacgccagcggcttccgctcgccgctggcacggcagttggggttgcgg
gaggagccgagccggctcaagcaccacgcccgctcgatcttcacccacatggtcggagtg
gacgcgatcgacgaccacgtggacacgccggccgagcttcgcccgccggtgccgtggaac
gacgggacgatgcaccacatcttcgagcgcggctggatgtggatcatcccgttcaacaac
caccccggggccaccaacccgctgtgcagcgtcggcatccagctcgacgagcgccgctac
cccgcccggccggacctgacgcccgaggaggagttctggtcccacgtggaccgcttcccg
gcggtgcagcggcagttgaagggcgcccgcagcgtgcgcgagtgggtgcgaacggaccgc
atgcagtactcctcgagccggacggtcggcgagcgctggtgcctgatgtcgcacgcggcc
ggcttcatcgacccgctcttctcccgcggcctgtccaacacctgcgagatcatcaacgcg
ctgtcctggcggctgatggccgcgctgcgcgaggacgacttcgcggtcgagcgcttcgcc
tacgtggaggaactggagcagggcctgctggactggaacgacaagctggtcaacaactcc
ttcatctccttctcgcactacccgctgtggaactcggtcttccggatctgggcctcggcc
agcgtgatcggcggcaagcgcatcctcaacgcactgaccaggaccaaggagaccggcgac
gacagccactgccaggcgctggacgacaacccgtacccgggcctgtggtgtccgctggac
ttctacaaggaggccttcgacgagctcaccgagctgtgcgaggccgtggacgccgggcac
accacggccgaggaggccgcgcgggtgctggagcagcgggtccgcgagtcggactggatg
ctgccggccctgggcttcaacgaccccgacacccaccacatcaacccgacggcggacaag
atgatccggatcgcggagtgggccaccggtcaccaccgcccggagatccgtgagctgctg
gccgccagcgccgaggaggtcagggcggcgatgcgggtcaagccgtaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
3D Structure (3)   
   PDB (3)   
Protein domain (14)   
   Pfam (14)   
All databases (51)   

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