KEGG   Kryptolebias marmoratus (mangrove rivulus): 108236362
Entry
108236362         CDS       T05608                                 
Symbol
tsc2
Name
(RefSeq) tuberin isoform X4
  KO
K07207  tuberous sclerosis 2
Organism
kmr  Kryptolebias marmoratus (mangrove rivulus)
Pathway
kmr04115  p53 signaling pathway
kmr04140  Autophagy - animal
kmr04150  mTOR signaling pathway
kmr04218  Cellular senescence
kmr04910  Insulin signaling pathway
kmr05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:kmr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    108236362 (tsc2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    108236362 (tsc2)
  09143 Cell growth and death
   04115 p53 signaling pathway
    108236362 (tsc2)
   04218 Cellular senescence
    108236362 (tsc2)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    108236362 (tsc2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    108236362 (tsc2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:kmr01009]
    108236362 (tsc2)
Protein phosphatases and associated proteins [BR:kmr01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     108236362 (tsc2)
SSDB
Motif
Pfam: Tuberin DUF3384 Rap_GAP
Other DBs
NCBI-GeneID: 108236362
NCBI-ProteinID: XP_017272436
Position
LG3:complement(23201056..23228277)
AA seq 1871 aa
MNKQQSKETLKDKVKGIFGLGTPRPQIKPCDPKLPEFIITSDIIKDLHPDNGLNNRIRVI
NQICDLAKMKRFEEHAVEAVWKAVEDMLTPEQPPEARHAVLQLLRAIIQGQGEWLGLLRA
YFFKVIRDYQPCNEDLSERLDVFKALTENGKDITYLEEDIARFVLLWMDIGLTSDFLHVL
VNLVKFNSCYLDQNVSIMVHKICMLCNRTTSSTDIEVALQVLDAVVCYNCLPSESLTIFI
ITLCRTVNVKEFCESCWKLMRKVLGTHLGHSAIYTMCRIMEERYCHYQMYMEDAPLLRGA
VFFVGMALWGAHRLPALKNTPTLVLPSFYKAMLCANEVVSYEIVLSITRLIKKYGKELQV
VTWDILLGIIEQLLQQILTIGSVELKAIVYELLTTVEELYEQNGYHGSTEKFFSLVEKCA
DKRADASVLTLISYRAQSIQPAKDGWIQSLHRLMEKFFKNETRSVIRIKVLHILSFVLST
NRQLYEDELIEMVVIPQLSGIAEDRDLAVRKQATQLLVDLAEGCNTHHFTSLLDIIERVA
SRSLVCPGALEVSERDPTAESPMEDVKTAVLGLLEILQSKLYSLPASHASRVYELLISHL
QLHYKNKYCSTIASTIRLQVFDFFLMMRADSLHRISVPNKDGAMRFSPYCYCDKGEPEKR
VGDKKPTGSTSPPAGSPAPPAAPPASTASIRSAYLPYAPAFNILLQCLKMEMDWKVLKLV
LDKLPWMLQYKVLLLTSKCSLDQLCSTLCLMVTDRLISDRLKRIPEGFSRTDVQLAVVPV
LTAITSYHNYLEQSRQRELVQCLETGLIYRCAKQCVVALTMCTVEMPDIMIKLLPALIVK
LTHISATVAMASPMLEFLSTLVRLPHLYANFVAEQYVSVFAISLPYTNPSKFNQYIVSLA
HHVIAMWFIRCRLPFRKDFVQYITKGLRSNALLPFDDGQEQSQFRARSTSLNERPKSLRA
AKVSKAAPVANSSSSPVKELRDLSAMDAFRSRSISVSEHAVRRMHTSTTTCSLGSADENA
VTQADEGLKTVHLELTETCLDMMARYVFSNFSALPKRSPIAEFLLAGGRSMTWLVGNKLV
TITTSGGVRTQALLGLDMSERLGGGGEMTRSDPSLHTRITKEAPATLESQSSQQHNRSTR
SRVRSMSGGHALRGGPTQSLSPLVSPSEGELTAPLSPSSGPALDGVGPPSSSSAASSAPP
PLKDNPSLAEFVPMLTQGWAEIFIRRPSGNTSWLMCLENPPSPFSSELGNMPLQELSSVL
MAMEGVKEPPAETSSAPASTAAPAPTSVSEPLNQTQSGVGGKPNLIQRSNTDSVVVLEEG
SGVTTPQTPIEWVEGEDFEPMPSEPIFMTPDKTAPPGTLSRSSSTSSQDDEKSTLEEVSE
GAIPIDQPALGPSTPGSQGPDLPFQSHSQSQGHGLNKSSSSPELQTLPEAFAKANMEAES
VQGDVCRPRAPSDGKPQVQQPLFEKDKAEGGAGGDVNGLGRQNQAGEGSGPSSQSGGLRL
AFPAAPAAQSGPISPGGGHRPRGHTISVSAPSSRRERRTERDSYHNRPGPSNTEKMSGLS
PSFVFLQLYHSPFFGNEANKPLLLPKTQVIDRAVKVLDQMPPYDTHKIGVVFVGAGQVNN
EVAILSNEYGSNRYAAFLTGLGKLIHLKDCDPDQIFLGGLDQYGDDGEFTYCWHDDIMQA
IFHIATLMPNRESDKGCCNKKRHIGNDFVMVVYNDSGEEYKLGTIKGQFNFVEVIIKPLD
YKCNLVSLQCRKDLEGLVDTTVAKIVSDRNLPLLVRQMALHANMASLVHQYRANPSDAYA
SKWLARLRHIKRIRTRAQEDIQSRSTPGISLTQGHAQQNKSFQQNTAAPNPEASGPRKRL
VSTVDDFTDFV
NT seq 5616 nt   +upstreamnt  +downstreamnt
atgaataaacaacaaagtaaggaaactctgaaggacaaggtgaaggggatctttggactc
gggactccccggccacagatcaaaccgtgcgaccctaagctgccggagtttattataact
tctgacattattaaggatctccacccagataacggcctgaacaaccggattcgggtcatc
aaccaaatttgtgatcttgcaaaaatgaaaagatttgaggagcatgcagtggaggccgtg
tggaaagctgtggaggacatgctgaccccagagcagccgccggaggccagacacgccgtc
ctgcagcttcttagggccattatacagggacagggtgagtggcttggccttttgagggcc
tactttttcaaggtgatcagagactaccaaccgtgcaacgaggacctctcagaaaggctg
gatgtgttcaaggctttaaccgaaaacgggaaggacatcacatacctcgaggaggacata
gcacgttttgttctcctgtggatggacattggtcttacttctgactttctccatgttctc
gtgaatctggtgaagtttaacagctgctacctggatcagaacgtctccatcatggtccat
aaaatctgtatgctgtgcaacagaacaacatcgtccacagatatagaggtggctcttcag
gtcttggatgccgttgtgtgctacaactgcctgccctcagagtccctcaccatttttatt
ataacactctgccgtacggttaatgtgaaggagttttgtgaatcctgctggaagttgatg
aggaaggttttggggactcatctgggccacagtgctatttacaccatgtgccgcatcatg
gaggagcggtattgtcactaccaaatgtacatggaggatgccccgctgctgagaggagcg
gtattctttgttggaatggcactgtggggcgcacacagactccctgccctgaaaaacaca
ccaacacttgtcctgccatccttctataaggccatgttgtgtgccaatgaggtggtgtcc
tatgaaatcgtcctctccatcaccagactgatcaagaagtacggcaaagagctgcaggtg
gtcacatgggacatcctgctgggcatcatagagcaactgctgcagcagatcctgacaata
ggcagtgtggagctgaaggcaattgtctacgagctcctgaccacggtggaagagctgtat
gagcagaacggttaccacggctccacggaaaagttcttcagtttggtggagaaatgtgcc
gacaagagagctgatgcgtcggtgctgacgctcatctcgtaccgggcgcagtccatccag
ccggccaaggacggctggattcagagccttcaccgcctcatggagaaattctttaagaac
gagactcgcagtgtgatacggatcaaagtgcttcatatcctgtccttcgttctcagcacc
aaccgacagctttatgaggatgagctgattgaaatggttgtgatccctcaactcagtggg
atagctgaagacagggatctggctgtcagaaagcaggctactcagcttctggtggatctc
gctgagggttgcaacacgcatcacttcaccagcctcctggacatcattgagcgggtggcc
agtcgttctctggtttgtccaggcgccctggaggtttctgagagagaccccacagctgag
tctcctatggaggatgtcaagacggctgtattgggtctgctggaaatcctgcagagcaaa
ctttacagcctaccagccagccatgcgagtcgtgtttatgagctgcttatcagccacctg
cagcttcactacaagaacaagtactgttcaaccatcgcctccactatcaggctacaggtg
tttgacttcttcctgatgatgcgtgcggactctctgcaccgcatcagcgttcccaacaag
gacggagcgatgagattcagcccgtactgctattgcgacaagggggagccggagaagcgt
gtcggtgataagaagccgacaggttcgacatctcctcctgctggtagtcctgctccgcct
gccgctcctccagcttcaacagcctccatacgctcagcttaccttccctacgctcctgcc
ttcaacatcctgctgcagtgcctcaaaatggaaatggattggaaggtgctgaaactggtt
ttggacaagctgccttggatgctgcagtacaaagtcctgctgctcacatcaaaatgcagt
ttagaccagctctgttccactctctgcctcatggtgacggatcgtctgatttctgaccgt
ctgaaaagaatcccggagggtttttcccgcacagacgttcagttggctgtggttcctgtt
ctcacagccataacctcctaccacaactacttggagcaatcgagacagagagagctggtt
cagtgcctcgagaccggcctcatttatcgatgtgccaagcagtgcgtggtggctcttaca
atgtgcacggtggagatgcctgacatcatgattaagctcctccctgcgctcatcgtcaag
ctcacccacatctctgctaccgttgccatggcatcccccatgctcgaattcctctccact
ctggtgcgtttgccccatctctacgccaactttgtagctgagcagtacgttagcgtgttt
gccatctcgctaccctataccaacccctctaagttcaaccagtatattgtgtctctggcc
catcacgtgatcgccatgtggttcatacgctgcagacttcccttccgcaaagactttgtt
cagtacatcacaaagggcttgcgttccaacgccctgctgcccttcgatgacggccaagag
cagagccagtttcgtgctcggagcaccagcctcaacgaaaggcccaaaagtctgcgagct
gcgaaagtgtcaaaggcggcccctgtagccaatagcagcagctctccagttaaagagctg
agggacctttcagccatggatgctttccgctcccgcagcatcagcgtctccgaacacgcg
gttcgcaggatgcacacctcaaccaccacctgcagtttgggctctgccgatgaaaacgct
gtgactcaggccgacgaggggctgaagacagtccacctggagctcacagagacctgtcta
gatatgatggctcgatatgtgttctccaacttctccgcgctgcccaagaggtctcccatc
gcagagttcctgttagccggaggtcgcagtatgacctggctggtggggaacaagctggtg
accatcacaaccagcggaggcgtaagaacgcaagcgttgctgggcctggacatgtctgaa
cgcctgggaggaggtggagaaatgaccaggtcagatccgtctctgcacacacggataacc
aaagaggctccagccacactggagtcccagtccagtcagcaacacaaccgatccacacgc
tcccgtgtccgctccatgtcagggggtcacgctctacgtggtggtcctacccagagtctc
agccctctggtctccccctctgagggggagctcactgctcctctgtctccctcctcgggc
cccgctctggatggtgtcggtcctccctcgtcctcctctgccgcctcctctgctcctcct
cctctcaaagataaccccagcctggctgagtttgtgccaatgctcactcagggctgggca
gaaatcttcatacggagaccttcaggcaacaccagctggctgatgtgtttggagaacccg
cccagtcccttttcctcggagctcggcaacatgccgctgcaggagctgtccagcgtcctg
atggcgatggagggagtgaaggagccccccgctgagacatccagcgctccagccagcaca
gccgccccagcacccacatctgtctctgagcctctgaaccaaacgcagagcggtgttgga
gggaagccaaacctgatccagcgttccaacaccgactctgtggtggtgctggaggagggg
tcaggggtcaccacacctcagaccccaattgagtgggtggagggggaagactttgagcca
atgccctccgagcccatattcatgactcctgacaagacggctcctcctggaacgctcagc
aggtcgtcctccacctccagtcaagatgatgaaaagtcaactctggaggaggtgagtgaa
ggagcgattcccatcgaccagccagctctgggcccctccaccccaggcagccaggggccc
gacctcccatttcagagccactcccagtcccagggtcacggactcaacaagtccagctcc
tccccggagctccagacgctgcctgaggccttcgccaaagctaatatggaggctgagagc
gtgcagggagacgtctgccggcccagagcgccctcagatggcaaacctcaggtacagcag
cccctttttgaaaaggacaaggcagaggggggagcaggaggggacgtaaacgggcttgga
cgtcagaaccaagcaggagaaggctccggtccgtcatctcagagtggagggttgaggttg
gcttttccagcagcaccagcagcacaatctggacccatctcacctggcggaggccaccgc
ccccggggtcacaccatttctgtttcagccccgtcctccaggagagaaaggaggacggag
agggactcgtatcacaatcgacccggacccagcaacacggagaagatgtccggtctgagc
cccagctttgtattcctccagttgtaccactctcctttctttgggaatgaagccaacaag
ccgctgctgctgcctaaaactcaggtgatcgaccgagctgtgaaggttctggaccagatg
cctccttatgacacccataagattggagtggtgtttgttggagccggtcaggtgaacaac
gaggtcgccatcctgtcgaacgaatacggctcaaaccgctatgccgccttcctgacaggc
ctggggaagctgatccacctgaaggactgcgaccccgaccagatctttcttggagggctg
gaccagtacggagacgatggagagttcacgtactgctggcacgatgacatcatgcaggcc
atcttccacatagctacactgatgccaaacagagagagcgataagggctgctgcaacaag
aagcggcacattggcaacgatttcgtcatggtggtgtacaacgactccggagaggagtac
aaactgggcacaatcaagggtcagtttaattttgtagaagtcatcattaaacccctggat
tataaatgtaaccttgtttcccttcagtgccgcaaagatctcgagggtttggtcgacacc
acagtggcgaagatcgtttctgatcgcaaccttccacttttagttcggcagatggccctg
catgcaaacatggcctccttggtgcaccagtacagagcgaacccctccgacgcgtacgct
tccaagtggctcgcaagattacggcacataaagaggatcagaaccagagctcaagaagac
atccagtcccgctcgactcctggaatctctctgacccaaggacacgctcagcagaacaag
tcgttccagcagaacacggcggctccgaaccccgaggcctccgggccgagaaagagactc
gtgtcgacagtggacgatttcaccgacttcgtttga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (6)   
   RefSeq(pep) (6)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (3)   
   Pfam (3)   
All databases (28)   

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