KEGG   ORTHOLOGY: K07408Help
Entry
K07408                      KO                                     

Name
CYP1A1
Definition
cytochrome P450 family 1 subfamily A polypeptide 1 [EC:1.14.14.1]
Pathway
ko00140  Steroid hormone biosynthesis
ko00380  Tryptophan metabolism
ko00830  Retinol metabolism
ko00980  Metabolism of xenobiotics by cytochrome P450
ko01100  Metabolic pathways
ko04913  Ovarian steroidogenesis
ko05204  Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1
 09160 Human Diseases
  09161 Cancers: Overview
   05204 Chemical carcinogenesis
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07408  CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP1 family
   K07408  CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1
BRITE hierarchy
Other DBs
RN: R02354 R02355 R03089 R03408 R03629 R07000 R07001 R07021 R07022 R07079 R07080 R07081 R07085 R07087 R07098 R07099 R08390 R08392 R09418 R09423 R09442
Genes
HSA: 1543(CYP1A1)
PTR: 453744(CYP1A1)
PPS: 100976184
GGO: 101129522
PON: 100457153
NLE: 100585507
MCC: 678694(CYP1A1)
MCF: 102129994(CYP1A1)
CSAB: 103245331(CYP1A1)
RRO: 104672151
RBB: 108531476
CJC: 100393083(CYP1A1)
SBQ: 101038217
MMU: 13076(Cyp1a1)
RNO: 24296(Cyp1a1)
CGE: 100751269
NGI: 103736921
HGL: 101707509
CCAN: 109701505
OCU: 100328613(CYP1A1)
TUP: 102484009
CFA: 100686778(CYP1A1)
UMR: 103678992
ORO: 101382250
FCA: 554347(CYP1A1)
PTG: 102966263
AJU: 106979443
BTA: 282870(CYP1A1)
BOM: 102283235
BIU: 109575587
PHD: 102320923
CHX: 102170823
OAS: 100170113(CYP1A1) 106992010
SSC: 403103(CYP1A1)
CFR: 102518111
CDK: 105087262
BACU: 103008057
LVE: 103071513
OOR: 101287158
ECB: 100062285(CYP1A1)
EAI: 106831264
MYB: 102262349
MYD: 102762200
HAI: 109396247
RSS: 109457837
PALE: 102892046
LAV: 100665901
TMU: 101359275
MDO: 100029871
SHR: 100927711
OAA: 100080942(CYP1A1)
GGA: 396051(CYP1A2) 396052(CYP1A1)
MGP: 100542486 664714(CYP1A5)
CJO: 107318670(CYP1A1) 107318671(CYP1A4)
FPG: 101910881
FCH: 102056146
AMJ: 102566713 102566943(CYP1A4)
CMY: 102933577(CYP1A) 102936296
XLA: 100036775(cyp1a1.L) 100337623(cyp1a1.S) 108706210
XTR: 100037911(cyp1a1)
NPR: 108789015
DRE: 140634(cyp1a)
IPU: 108264711(cyp1a1)
PHYP: 113534518
TRU: 101074542
LCO: 104920743
NCC: 104963340
MZE: 101465118
OLA: 100125806(cyp1a)
XMA: 102234246
PRET: 103462617
NFU: 107382111
KMR: 108243353
CSEM: 103379316
LCF: 108897725
SDU: 111221785
HCQ: 109513991
BPEC: 110175505
MALB: 109955886
SASA: 100136916(cyp1a) 100136926(cyp1a)
ELS: 105015303
LCM: 102357693
CMK: 103188936
APLC: 110973623
FCD: 110853545
MYI: 110453402
CSAT: 104734701
ADU: 107486986
ZJU: 107430007
CSV: 101204800
PDA: 113462711
MUS: 103990446
DCT: 110097959
ATR: 18446184
AG: BAA88242(CYP1A9)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2989797
  Authors
Jaiswal AK, Gonzalez FJ, Nebert DW
  Title
Human P1-450 gene sequence and correlation of mRNA with genetic differences in benzo[a]pyrene metabolism.
  Journal
Nucleic Acids Res 13:4503-20 (1985)
DOI:10.1093/nar/13.12.4503
  Sequence
[hsa:1543]
Reference
PMID:3019683
  Authors
Kawajiri K, Watanabe J, Gotoh O, Tagashira Y, Sogawa K, Fujii-Kuriyama Y
  Title
Structure and drug inducibility of the human cytochrome P-450c gene.
  Journal
Eur J Biochem 159:219-25 (1986)
DOI:10.1111/j.1432-1033.1986.tb09857.x
  Sequence
[hsa:1543]

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