ko:K00233 : No such data.

KEGG   ORTHOLOGY: K00234Help
Entry
K00234                      KO                                     

Name
SDHA, SDH1
Definition
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
Pathway
ko00020  Citrate cycle (TCA cycle)
ko00190  Oxidative phosphorylation
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01120  Microbial metabolism in diverse environments
ko01130  Biosynthesis of antibiotics
ko01200  Carbon metabolism
ko04714  Thermogenesis
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05016  Huntington disease
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00148  Succinate dehydrogenase (ubiquinone)
Disease
H00294  Dilated cardiomyopathy (DCM)
H01022  Diseases of the tricarboxylic acid cycle
H01354  Leigh syndrome
H02005  Mitochondrial complex II deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit
 09160 Human Diseases
  09163 Neurodegenerative diseases
   05010 Alzheimer disease
    K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit
   05012 Parkinson disease
    K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit
   05016 Huntington disease
    K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit
  09166 Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Central carbohydrate metabolism
    M00009  Citrate cycle (TCA cycle, Krebs cycle)
     K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit
    M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
     K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit
 Structural complex
  Energy metabolism
   ATP synthesis
    M00148  Succinate dehydrogenase (ubiquinone)
     K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.5  With a quinone or related compound as acceptor
    1.3.5.1  succinate dehydrogenase
     K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit
BRITE hierarchy
Other DBs
RN: R02164
COG: COG1053
GO: 0008177
Genes
HSA: 6389(SDHA)
PTR: 107974583(SDHA)
PPS: 100987473(SDHA)
GGO: 101124208 101141874(SDHA) 101147313
PON: 100173631(SDHA)
NLE: 100580596 100593202(SDHA) 100594023
MCC: 708018(SDHA)
MCF: 102126003
CSAB: 103215231(SDHA) 103215235
RRO: 104659264 104662045 104668708(SDHA)
CJC: 100400483(SDHA)
SBQ: 101049489(SDHA)
MMU: 66945(Sdha)
RNO: 157074(Sdha)
CGE: 100750732(Sdha)
NGI: 103749659(Sdha)
HGL: 101697591(Sdha)
CCAN: 109693457(Sdha)
OCU: 100328584(SDHA)
TUP: 102502720(SDHA)
CFA: 478634(SDHA)
AML: 100483034(SDHA)
UMR: 103679246(SDHA)
ORO: 101382073(SDHA)
FCA: 751619(SDHA)
PTG: 102949810(SDHA)
AJU: 106988566(SDHA)
BTA: 281480(SDHA)
BOM: 102278228(SDHA)
PHD: 102332015(SDHA)
CHX: 102183107(SDHA)
OAS: 100036762(SDHA)
SSC: 780433(SDHA)
CFR: 102523856(SDHA)
CDK: 105102189(SDHA)
BACU: 103005047(SDHA)
LVE: 103090475(SDHA)
OOR: 101271279(SDHA)
ECB: 100034244(SDHA)
EPZ: 103560327(SDHA)
EAI: 106835869(SDHA)
MYB: 102240483(SDHA)
MYD: 102766070(SDHA)
HAI: 109371695(SDHA)
RSS: 109440254 109454181(SDHA)
PALE: 102897292(SDHA)
LAV: 100141371(SDHA)
TMU: 101357812
MDO: 751085(SDHA)
SHR: 100931806(SDHA)
OAA: 100083131(SDHA)
GGA: 395758(SDHA)
MGP: 100546340(SDHA)
CJO: 107309446(SDHA)
APLA: 101792265(SDHA)
ACYG: 106045013(SDHA)
TGU: 100217509 100230079(SDHA)
GFR: 102036351(SDHA)
FAB: 101819469(SDHA)
PHI: 102108670(SDHA)
PMAJ: 107200805(SDHA)
CCW: 104685847(SDHA)
FPG: 101916111(SDHA)
FCH: 102047706(SDHA)
CLV: 102093871(SDHA)
EGZ: 104128506(SDHA)
AAM: 106492875(SDHA)
ASN: 102372796(SDHA)
AMJ: 102561508(SDHA)
PSS: 102455030(SDHA)
CMY: 102943548(SDHA)
CPIC: 101930831(SDHA)
ACS: 100551545(sdha)
PVT: 110090570(SDHA)
GJA: 107118404(SDHA)
XLA: 380463(sdha.S) 398946(sdha.L)
XTR: 548743(sdha)
NPR: 108803812(SDHA)
DRE: 393884(sdha)
IPU: 108272761(sdha)
AMEX: 103022581(sdha)
TRU: 101076572(sdha)
LCO: 104928090(sdha) 109138819
NCC: 104952821(sdha)
MZE: 101470960(sdha)
XMA: 102235474(sdha)
PRET: 103478296(sdha)
NFU: 107378888(sdha)
CSEM: 103388781(sdha)
LCF: 108888123(sdha)
HCQ: 109529672(sdha)
BPEC: 110171397(sdha)
SFM: 108931739(sdha)
LCM: 102348838(SDHA)
CMK: 103181549(sdha)
CIN: 100183000
SPU: 580610
APLC: 110986692
SKO: 100371134
DME: Dmel_CG17246(SdhA) Dmel_CG5718(SdhAL)
DSI: Dsimw501_GD12763(Dsim_GD12763) Dsimw501_GD25325(Dsim_GD25325)
MDE: 101898176
AAG: 5575223
AME: 408734(GB15847) 550667(SdhA)
NVI: 100119074(Sdha) 100119112
NVL: 108560967
API: 100166540
DNX: 107161701
ZNE: 110840631
FCD: 110845478
TUT: 107362728
CEL: CELE_C03G5.1(sdha-1) CELE_C34B2.7(sdha-2)
CBR: CBG12805(Cbr-sdha-2) CBG22795(Cbr-sdha-1)
BMY: Bm1_17330
TSP: Tsp_06974
CRG: 105337089
MYI: 110450908
SHX: MS3_00508
EPA: 110233821
HMG: 100210215
AQU: 100632409
ATH: AT2G18450(SDH1-2) AT5G66760(SDH1-1)
ALY: ARALYDRAFT_480752(SDH1-2) ARALYDRAFT_496924(SDH1-1)
CPAP: 110822288
CIT: 102623970
TCC: 18610944
EGR: 104419754
LJA: Lj4g3v0948900.1(Lj4g3v0948900.1)
ADU: 107487854
AIP: 107642871
FVE: 101303935
PPER: 18769030
PMUM: 103340079
PAVI: 110773605
ZJU: 107424596
CSV: 101211616
CMO: 103494381
MCHA: 111008239
CMAX: 111483154
CMOS: 111435915
CPEP: 111810124
RCU: 8283123
JCU: 105641357
VVI: 100254718
SLY: 101256641
SPEN: 107011073
SOT: 102604123
CANN: 107859955
NSY: 104241425
NTO: 104115838
LSV: 111901866
BVG: 104895015
SOE: 110803652
OSA: 4342350
DOSA: Os07t0134800-01(Os07g0134800)
OBR: 102704350
ATS: 109753010(LOC109753010) 109757946(LOC109757946)
ZMA: 100279930(TIDP3457) 100280324 103636824
DCT: 110098030
ATR: 18445831
CRE: CHLREDRAFT_195972(SDH1)
VCN: VOLCADRAFT_74298(sdh1)
MIS: MICPUN_106467(SDH2)
APRO: F751_1347
SCE: YJL045W YKL148C(SDH1)
ERC: Ecym_8248
KMX: KLMA_20466(SDH1)
NCS: NCAS_0F02320(NCAS0F02320)
NDI: NDAI_0C03810(NDAI0C03810)
TPF: TPHA_0E02930(TPHA0E02930)
TBL: TBLA_0A10080(TBLA0A10080)
TDL: TDEL_0E03730(TDEL0E03730)
KAF: KAFR_0H03590(KAFR0H03590)
PIC: PICST_66251(SDH1)
CAUR: QG37_03344
SLB: AWJ20_4699(SDH1)
NCR: NCU08336(tca-12)
NTE: NEUTE1DRAFT71896(NEUTE1DRAFT_71896)
MGR: MGG_00168
MAW: MAC_01061
MAJ: MAA_05673
CMT: CCM_02366
MBE: MBM_01461
ANI: AN2916.2
ANG: ANI_1_1750024(An02g12770) ANI_1_2706024(An02g07600)
ABE: ARB_06591
TVE: TRV_04812
PNO: SNOG_07395(SNOG_07394) SNOG_16547(SNOG_16546)
SPO: SPAC1556.02c(sdh1)
CNE: CNI03270
CNB: CNBH3130
ABP: AGABI1DRAFT111304(SDH1)
ABV: AGABI2DRAFT190526(SDH1)
SLA: SERLADRAFT_475471(SDH1)
MGL: MGL_3463
DDI: DDB_G0280535(sdhA)
DFA: DFA_01593(sdhA)
PYO: PY17X_0519300(PY05468)
PCB: PCHAS_051830(PC001322.02.0)
TAN: TA03455
TPV: TP03_0230
BBO: BBOV_IV007210(23.m06369)
SMIN: v1.2.013871.t1(symbB.v1.2.013871.t1) v1.2.031094.t1(symbB.v1.2.031094.t1)
PTI: PHATR_41812(SDH1)
FCY: FRACYDRAFT_173934(SDH5)
SPAR: SPRG_13201
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8142412
  Authors
Morris AA, Farnsworth L, Ackrell BA, Turnbull DM, Birch-Machin MA
  Title
The cDNA sequence of the flavoprotein subunit of human heart succinate dehydrogenase.
  Journal
Biochim Biophys Acta 1185:125-8 (1994)
DOI:10.1016/0005-2728(94)90203-8
  Sequence
[hsa:6389]
Reference
  Authors
Renkema GH, Wortmann SB, Smeets RJ, Venselaar H, Antoine M, Visser G, Ben-Omran T, van den Heuvel LP, Timmers HJ, Smeitink JA, Rodenburg RJ
  Title
SDHA mutations causing a multisystem mitochondrial disease: novel mutations and genetic overlap with hereditary tumors.
  Journal
Eur J Hum Genet 23:202-9 (2015)
DOI:10.1038/ejhg.2014.80

KEGG   ORTHOLOGY: K00235Help
Entry
K00235                      KO                                     

Name
SDHB, SDH2
Definition
succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
Pathway
ko00020  Citrate cycle (TCA cycle)
ko00190  Oxidative phosphorylation
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01120  Microbial metabolism in diverse environments
ko01130  Biosynthesis of antibiotics
ko01200  Carbon metabolism
ko04714  Thermogenesis
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05016  Huntington disease
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00148  Succinate dehydrogenase (ubiquinone)
Disease
H01222  Cowden syndrome
H01510  Malignant paraganglioma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit
 09160 Human Diseases
  09163 Neurodegenerative diseases
   05010 Alzheimer disease
    K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit
   05012 Parkinson disease
    K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit
   05016 Huntington disease
    K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit
  09166 Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Central carbohydrate metabolism
    M00009  Citrate cycle (TCA cycle, Krebs cycle)
     K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit
    M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
     K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit
 Structural complex
  Energy metabolism
   ATP synthesis
    M00148  Succinate dehydrogenase (ubiquinone)
     K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.5  With a quinone or related compound as acceptor
    1.3.5.1  succinate dehydrogenase
     K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit
BRITE hierarchy
Other DBs
RN: R02164
COG: COG0479
GO: 0008177
Genes
HSA: 6390(SDHB)
PTR: 456526(SDHB)
PPS: 100989574(SDHB)
GGO: 101131972(SDHB)
PON: 100437700(SDHB)
NLE: 100582706(SDHB)
MCC: 699810(SDHB)
MCF: 101865119(SDHB)
CSAB: 103225507(SDHB)
RRO: 104669912(SDHB)
RBB: 108515327(SDHB)
CJC: 100403702(SDHB)
SBQ: 101044303(SDHB)
MMU: 67680(Sdhb)
RNO: 298596(Sdhb)
CGE: 100771246(Sdhb)
NGI: 103725310(Sdhb)
HGL: 101720891(Sdhb)
CCAN: 109689825(Sdhb)
OCU: 100328585(SDHB)
TUP: 102480936(SDHB)
CFA: 478217(SDHB)
AML: 100473290(SDHB)
UMR: 103666614(SDHB)
ORO: 101380075(SDHB)
FCA: 751617(SDHB)
PTG: 102961107(SDHB)
AJU: 106975612(SDHB)
BTA: 286840(SDHB)
BOM: 102274978(SDHB)
BIU: 109574556(SDHB)
PHD: 102315900(SDHB)
CHX: 102183195(SDHB)
OAS: 101108729(SDHB) 101110243
SSC: 414412(SDHB)
CFR: 102524547(SDHB)
CDK: 105107079(SDHB)
BACU: 103013798(SDHB)
LVE: 103078950(SDHB)
OOR: 101278085(SDHB)
ECB: 100050091(SDHB)
EPZ: 103540492(SDHB)
EAI: 106827983(SDHB)
MYB: 102242794 102254448(SDHB)
MYD: 102752857(SDHB) 102771621
HAI: 109389410(SDHB)
RSS: 109442979 109458977(SDHB)
PALE: 102894659(SDHB)
LAV: 100141376(SDHB)
TMU: 101353562
MDO: 751078(SDHB)
SHR: 100924299(SDHB)
OAA: 100074487(SDHB)
GGA: 100859720(SDHB)
MGP: 100543850(SDHB)
CJO: 107323469(SDHB)
APLA: 101793933(SDHB)
ACYG: 106040166(SDHB)
TGU: 100190642(SDHB)
GFR: 102037337(SDHB)
FAB: 101817512 101819204(SDHB)
PHI: 102114745(SDHB)
PMAJ: 107213507(SDHB)
FPG: 101918141(SDHB)
FCH: 102047150(SDHB)
CLV: 102091815
EGZ: 104133181(SDHB)
AAM: 106484668(SDHB)
ASN: 102373063(SDHB)
AMJ: 102575823(SDHB)
PSS: 102445790(SDHB)
CMY: 102940700(SDHB)
CPIC: 101939393(SDHB) 101949570
ACS: 100556555(sdhb)
PVT: 110073147(SDHB)
PBI: 103065195(SDHB)
GJA: 107111390(SDHB)
XLA: 108696840(sdhb.L) 379939(sdhb.S)
XTR: 100144957(sdhb)
NPR: 108803746(SDHB)
DRE: 562149(sdhb)
IPU: 100528601(sdhb)
AMEX: 103031341(sdhb)
TRU: 101072453(sdhb) 101075255
NCC: 104949017 104959019(sdhb)
NFU: 107385781(sdhb)
CSEM: 103385849(sdhb)
ELS: 105017105(sdhb)
LCM: 102358325(RCC2)
CMK: 103187447(sdhb)
CIN: 100181830
SPU: 589263
APLC: 110979126
SKO: 100369462
DME: Dmel_CG3283(SdhB) Dmel_CG7349(SdhBL)
DSI: Dsimw501_GD10425(Dsim_GD10425) Dsimw501_GD17417(Dsim_GD17417)
AAG: 5573238
AME: 551169(GB14832) 551917(GB17542) 727212
NVI: 100116862(SdhB) 100117703
TCA: 658066(SdhB) 663097
NVL: 108559005
API: 100162363(Sdhb)
DNX: 107169875
ZNE: 110826970
FCD: 110848850
TUT: 107366097
CEL: CELE_F42A8.2(sdhb-1)
CBR: CBG00872(Cbr-sdhb-1)
BMY: Bm1_17690
TSP: Tsp_09576
MYI: 110440487
OBI: 106881280
SHX: MS3_09457
ADF: 107333862
HMG: 100206520
AQU: 100632374
ATH: AT3G27380(SDH2-1) AT5G40650(SDH2-2) AT5G65165(SDH2-3)
VRA: 106762873
VAR: 108334450
CCAJ: 109812842
CAM: 101492705
LJA: Lj0g3v0336519.1(Lj0g3v0336519.1) Lj1g3v3740570.1(Lj1g3v3740570.1) Lj1g3v3751710.1(Lj1g3v3751710.1) Lj1g3v3751710.2(Lj1g3v3751710.2) Lj4g3v0485140.1(Lj4g3v0485140.1)
LANG: 109350651
CSV: 101209955 101220767(SDHB)
POP: 7456195
NNU: 104607007
DOSA: Os08t0120000-01(Os08g0120000) Os09t0370300-01(Os09g0370300)
ATS: 109762674(LOC109762674) 109763002(LOC109763002)
SITA: 101774368
DCT: 110102371
AOF: 109824390
PPP: 112289680
CRE: CHLREDRAFT_142231(SDH2)
VCN: VOLCADRAFT_78776(sdh2)
MNG: MNEG_7619
MIS: MICPUN_105014(SDH1)
SCE: YLL041C(SDH2)
ERC: Ecym_8411
KMX: KLMA_80408(SDH2)
NCS: NCAS_0A02980(NCAS0A02980) NCAS_0C05870(NCAS0C05870)
NDI: NDAI_0D04950(NDAI0D04950) NDAI_0H00250(NDAI0H00250)
TPF: TPHA_0F00210(TPHA0F00210)
TBL: TBLA_0E01400(TBLA0E01400)
TDL: TDEL_0G01780(TDEL0G01780)
KAF: KAFR_0L00230(KAFR0L00230)
PIC: PICST_50416(SDH2)
CAL: CAALFM_CR05180CA(SDH2)
CAUR: QG37_03977
SLB: AWJ20_2469(SDH2)
NCR: NCU00959(tca-10)
NTE: NEUTE1DRAFT118669(NEUTE1DRAFT_118669)
MGR: MGG_00167
MAW: MAC_09331
MAJ: MAA_03382
CMT: CCM_07146
BFU: BCIN_01g04980(Bcsdh2)
MBE: MBM_04777
ANI: AN2332.2
ANG: ANI_1_1422124(An14g04400)
ABE: ARB_02933
TVE: TRV_07643
PTE: PTT_14436
ZTR: MYCGRDRAFT_74146(SDH2)
SPO: SPAC140.01(sdh2)
CNE: CNG03480
CNB: CNBG1290
ABP: AGABI1DRAFT115047(SDH2)
ABV: AGABI2DRAFT195434(SDH2)
SLA: SERLADRAFT_478574(SDH2)
MGL: MGL_3104
DDI: DDB_G0270120(sdhB)
PYO: PY17X_1430900(PY04921)
PCB: PCHAS_143060(PC000220.05.0)
TAN: TA19430
TPV: TP01_0210
BBO: BBOV_IV005280(23.m06368)
SMIN: v1.2.008970.t1(symbB.v1.2.008970.t1) v1.2.020965.t1(symbB.v1.2.020965.t1)
PTI: PHATRDRAFT_52539(SDH2)
TPS: THAPSDRAFT_32945(SDH1)
SPAR: SPRG_14325
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2302193
  Authors
Kita K, Oya H, Gennis RB, Ackrell BA, Kasahara M
  Title
Human complex II (succinate-ubiquinone oxidoreductase): cDNA cloning of iron sulfur (Ip) subunit of liver mitochondria.
  Journal
Biochem Biophys Res Commun 166:101-8 (1990)
DOI:10.1016/0006-291X(90)91916-G
  Sequence
[hsa:6390]

KEGG   ORTHOLOGY: K00236Help
Entry
K00236                      KO                                     

Name
SDHC, SDH3
Definition
succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
Pathway
ko00020  Citrate cycle (TCA cycle)
ko00190  Oxidative phosphorylation
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01120  Microbial metabolism in diverse environments
ko01130  Biosynthesis of antibiotics
ko01200  Carbon metabolism
ko04714  Thermogenesis
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05016  Huntington disease
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00148  Succinate dehydrogenase (ubiquinone)
Disease
H01510  Malignant paraganglioma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
 09160 Human Diseases
  09163 Neurodegenerative diseases
   05010 Alzheimer disease
    K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
   05012 Parkinson disease
    K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
   05016 Huntington disease
    K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
  09166 Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Central carbohydrate metabolism
    M00009  Citrate cycle (TCA cycle, Krebs cycle)
     K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
    M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
     K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
 Structural complex
  Energy metabolism
   ATP synthesis
    M00148  Succinate dehydrogenase (ubiquinone)
     K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
BRITE hierarchy
Other DBs
RN: R02164
COG: COG2009
Genes
HSA: 6391(SDHC)
PTR: 747462(SDHC)
PPS: 100974183(SDHC)
GGO: 101127794(SDHC)
PON: 100936632(SDHC)
NLE: 100607083(SDHC)
MCC: 701966 702309 704336 719978(SDHC)
MCF: 102127185 102127751 102134309 102145957(SDHC)
CSAB: 103216985 103223678(SDHC) 103225005
RRO: 104663917 104665348(SDHC) 104669001 104675621
CJC: 100386976(SDHC)
SBQ: 101051329 101052834(SDHC)
MMU: 66052(Sdhc)
RNO: 289217(Sdhc)
CGE: 100689402(Sdhc)
NGI: 103745944(Sdhc)
HGL: 101698043(Sdhc)
CCAN: 109690415(Sdhc)
OCU: 103350026(SDHC)
TUP: 102502200(SDHC)
CFA: 478983(SDHC)
AML: 100480530(SDHC)
UMR: 103672010(SDHC)
ORO: 101369754(SDHC) 101372902
FCA: 101087808(SDHC)
PTG: 102958685(SDHC)
AJU: 106978541(SDHC)
BTA: 327696(SDHC)
BOM: 102277085(SDHC)
BIU: 109578214(SDHC)
PHD: 102316971(SDHC) 102322485
CHX: 102189176(SDHC)
OAS: 101105616(SDHC)
SSC: 100524676(SDHC)
CFR: 102506175(SDHC)
CDK: 105100098(SDHC)
BACU: 103010344(SDHC)
LVE: 103086971(SDHC)
OOR: 101275408 101275820(SDHC)
ECB: 100065940(SDHC)
EPZ: 103560002(SDHC)
EAI: 106827584(SDHC)
MYB: 102263682(SDHC)
MYD: 102753591(SDHC)
HAI: 109376939(SDHC)
RSS: 109435236(SDHC)
PALE: 102894125(SDHC)
LAV: 100672637(SDHC)
TMU: 101346550
MDO: 100032780(SDHC)
SHR: 100918297(SDHC)
OAA: 100089418(SDHC)
GGA: 100859641(SDHC)
MGP: 100548835(SDHC)
CJO: 107307598(SDHC)
APLA: 101802517(SDHC)
ACYG: 106029435(SDHC)
GFR: 102038373(SDHC)
PHI: 102103522(SDHC)
FPG: 101915881(SDHC)
FCH: 102056902(SDHC)
CLV: 102095156(SDHC)
EGZ: 104127925(SDHC)
ASN: 102377538(SDHC)
AMJ: 102574235(SDHC)
PSS: 102446091(SDHC)
CMY: 102948093(SDHC)
CPIC: 101933232(SDHC)
ACS: 100562191(sdhc)
PVT: 110081034(SDHC)
PBI: 103065849(SDHC)
GJA: 107109900(SDHC)
XLA: 108700387(sdhc.S)
XTR: 496650(sdhc)
NPR: 108795020(SDHC)
DRE: 445129(sdhc)
IPU: 108280353(sdhc)
AMEX: 103032928(sdhc)
TRU: 101065852(sdhc)
LCO: 104926548(sdhc)
NCC: 104955460(sdhc)
MZE: 101481845(sdhc)
OLA: 101162241(sdhc)
XMA: 102233308(sdhc)
NFU: 107383463(sdhc)
CSEM: 103396778(sdhc)
LCF: 108884322(sdhc)
HCQ: 109529551(sdhc)
BPEC: 110175120(sdhc)
SASA: 106569582(C560) 106600492(C560)
ELS: 105024551(sdhc)
SFM: 108937816(sdhc)
LCM: 102357531(SDHC)
CIN: 101242735
SPU: 577495
APLC: 110982044
DSI: Dsimw501_GD20679(Dsim_GD20679) Dsimw501_GD20687(Dsim_GD20687)
AAG: 5571173
AME: 409549(SdhC)
BIM: 100743450
BTER: 100647436
SOC: 105196867
AEC: 105150305
ACEP: 105623534
PBAR: 105431267
HST: 105184891
CFO: 105258646
LHU: 105669430
PGC: 109853095
NVI: 100114948(SdhC)
DPA: 109541493
NVL: 108559531
BMOR: 101742176
API: 100165770
DNX: 107164693
ZNE: 110831845
FCD: 110844521
TUT: 107369074
CEL: CELE_T07C4.7(mev-1)
CBR: CBG24607(Cbr-mev-1)
BMY: Bm1_30090
TSP: Tsp_06231
CRG: 105332143
MYI: 110464279
OBI: 106870459
SHX: MS3_06834
EPA: 110241165
ADF: 107335287
HMG: 100215666
AQU: 100633388
ATH: AT4G32210(SDH3-2) AT5G09600(SDH3-1)
ALY: ARALYDRAFT_487775(SDH3-1)
BRP: 103847217
BOE: 106313249
THJ: 104799736
CPAP: 7441433(sdh3)
GRA: 105777434 27429632(sdh3)
GMX: 100499683 100527396(sdh3)
VRA: 106777138
CCAJ: 109814241
CAM: 101495449
LJA: Lj3g3v2905120.1(Lj3g3v2905120.1)
ADU: 107477767
AIP: 107629966
FVE: 101297104
MDM: 103449071
PXB: 103947548
ZJU: 107406236 27215257(sdh3)
CSV: 11123870(sdh3)
RCU: 10221405(sdh3)
POP: 7457745
VVI: 7498669(sdh3)
CANN: 19989013(sdh3)
NTA: 3205214(sdh3) 3205233(sdh3) 3205300(sdh3)
NSY: 27214839(sdh3) 27214871(sdh3) 27214890(sdh3)
INI: 109168516
HAN: 110884287
DCR: 108192842
BVG: 104902643
NNU: 28482651(sdh3b) 28482709(sdh3a)
DOSA: Os02t0121800-01(Os02g0121800) Os07t0521000-01(Os07g0521000)
ATS: 109747450(LOC109747450) 109759963(LOC109759963)
SBI: 8080288
ZMA: 100281355(TIDP2767) 100283351
SITA: 101764948
EGU: 105051662
DCT: 110106551
PPP: 3989115(sdh3)
CRE: CHLREDRAFT_195641(SDH3)
APRO: F751_6400
CCP: ChcroMp10(sdh3)
SCE: YKL141W(SDH3) YMR118C(SHH3)
ERC: Ecym_6091
NCS: NCAS_0A04200(NCAS0A04200)
NDI: NDAI_0E01940(NDAI0E01940)
TPF: TPHA_0G02790(TPHA0G02790)
TBL: TBLA_0H00360(TBLA0H00360)
TDL: TDEL_0A01980(TDEL0A01980)
KAF: KAFR_0A00490(KAFR0A00490) KAFR_0D02880(KAFR0D02880)
PIC: PICST_35527(SDH6)
CAL: CAALFM_C201690WA(CaO19.1480)
CAUR: QG37_02670
NCR: NCU07756(tca-11)
NTE: NEUTE1DRAFT94058(NEUTE1DRAFT_94058)
MGR: MGG_04876
MAW: MAC_07317
MAJ: MAA_09741
CMT: CCM_09238
MBE: MBM_08479
ANI: AN8793.2
ANG: ANI_1_390064(An07g03170)
ABE: ARB_06978
TVE: TRV_00347
PTE: PTT_14754
SPO: SPCC330.12c(sdh3)
CNE: CNA03530
CNB: CNBA3400
SLA: SERLADRAFT_370178(SDH3)
MGL: MGL_0528
DDI: DDB_G0275115(sdhC)
DFA: DFA_02826(sdhC)
FCY: FRACYDRAFT_271472(SDH1)
SPAR: SPRG_11501
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9714607
  Authors
Elbehti-Green A, Au HC, Mascarello JT, Ream-Robinson D, Scheffler IE
  Title
Characterization of the human SDHC gene encoding of the integral membrane proteins of succinate-quinone oxidoreductase in mitochondria.
  Journal
Gene 213:133-40 (1998)
DOI:10.1016/S0378-1119(98)00186-3
  Sequence
[hsa:6391]

KEGG   ORTHOLOGY: K00237Help
Entry
K00237                      KO                                     

Name
SDHD, SDH4
Definition
succinate dehydrogenase (ubiquinone) membrane anchor subunit
Pathway
ko00020  Citrate cycle (TCA cycle)
ko00190  Oxidative phosphorylation
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01120  Microbial metabolism in diverse environments
ko01130  Biosynthesis of antibiotics
ko01200  Carbon metabolism
ko04714  Thermogenesis
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05016  Huntington disease
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00148  Succinate dehydrogenase (ubiquinone)
Disease
H00034  Carcinoid
H01222  Cowden syndrome
H01510  Malignant paraganglioma
H02005  Mitochondrial complex II deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
 09160 Human Diseases
  09163 Neurodegenerative diseases
   05010 Alzheimer disease
    K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
   05012 Parkinson disease
    K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
   05016 Huntington disease
    K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
  09166 Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Central carbohydrate metabolism
    M00009  Citrate cycle (TCA cycle, Krebs cycle)
     K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
    M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
     K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
 Structural complex
  Energy metabolism
   ATP synthesis
    M00148  Succinate dehydrogenase (ubiquinone)
     K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
BRITE hierarchy
Other DBs
RN: R02164
COG: COG2142
Genes
HSA: 6392(SDHD)
PTR: 451547(SDHD)
PPS: 100975025(SDHD) 100992849
GGO: 101141433 101141792 101151822 109028866(SDHD)
PON: 100172275(SDHD)
NLE: 100584747(SDHD) 100590500 101178881
MCC: 106992278(SDHD) 711326(SDHD)
MCF: 102132064(SDHD)
CSAB: 103240581 103248461(SDHD)
RRO: 104677354(SDHD)
RBB: 108536453(SDHD)
CJC: 100413949(SDHD)
SBQ: 101028994(SDHD)
MMU: 66925(Sdhd)
RNO: 363061(Sdhd)
CGE: 100774657(Sdhd)
NGI: 103733879(Sdhd)
HGL: 101702014(Sdhd)
CCAN: 109699440(Sdhd)
CFA: 479438(SDHD)
ORO: 101369783(SDHD)
FCA: 101095280(SDHD) 111557658
PTG: 102952867(SDHD)
AJU: 106975241 106984276(SDHD)
BTA: 281481(SDHD)
BOM: 102281830(SDHD)
BIU: 109556917(SDHD)
CHX: 100860881(SDHD)
OAS: 101111485(SDHD) 780442 780772
SSC: 100048954(SDHD)
CFR: 102521513(SDHD)
CDK: 105094129(SDHD)
BACU: 103014249(SDHD)
LVE: 103087853(SDHD)
OOR: 101271681(SDHD) 101277363
ECB: 100629334(SDHD)
EPZ: 103565881(SDHD)
EAI: 106840217(SDHD)
MYB: 102259933(SDHD)
MYD: 102763784(SDHD)
HAI: 109388702(SDHD)
RSS: 109436603(SDHD)
PALE: 102885251(SDHD)
LAV: 100655924 100668090(SDHD)
TMU: 101348027
MDO: 100032261(SDHD)
SHR: 100916627(SDHD)
GGA: 419793(SDHD)
MGP: 104909347(SDHD)
CJO: 107324125(SDHD)
APLA: 101804599(SDHD)
ACYG: 106039722(SDHD)
GFR: 102032079(SDHD)
FAB: 107604174(SDHD)
PHI: 102105389(SDHD)
PMAJ: 107214401(SDHD)
CCW: 104692077(SDHD)
FPG: 101915216(SDHD)
FCH: 102046315(SDHD)
CLV: 102089042(SDHD)
EGZ: 104125935(SDHD)
ASN: 102375141(SDHD)
AMJ: 102571129(SDHD)
PSS: 102453028(SDHD)
CMY: 102934024(SDHD)
CPIC: 101931568(SDHD)
PVT: 110079388(SDHD)
PBI: 103052888(SDHD)
GJA: 107116139(SDHD)
XLA: 494586(sdhd.S) 496372(sdhd.L)
XTR: 394986(sdhd)
NPR: 108801745(SDHD)
DRE: 436762(sdhda) 445500(sdhdb)
IPU: 108277787(sdhd)
AMEX: 103030352(sdhd)
TRU: 101073558(sdhd)
LCO: 104940581(sdhd)
NCC: 104945632(sdhd)
MZE: 101471207(sdhd)
OLA: 101167814(sdhd)
XMA: 102225550(sdhd)
PRET: 103474368(sdhd)
NFU: 107380753(sdhd)
CSEM: 103377767(sdhd)
LCF: 108900022(sdhd)
HCQ: 109510914(sdhd)
BPEC: 110162000(sdhd)
ELS: 105024040(sdhd)
SFM: 108928640(sdhd)
LCM: 102347390(SDHD)
CMK: 103191157(sdhd)
CIN: 100180725
SPU: 588082
APLC: 110990396
SKO: 100371519
DME: Dmel_CG10219(SdhD)
DSI: Dsimw501_GD18356(Dsim_GD18356)
AAG: 5573489
AME: 725566
BIM: 100742104
BTER: 100650698
SOC: 105203611
AEC: 105150009
ACEP: 105625215
PBAR: 105432798
HST: 105183236
CFO: 105250939
LHU: 105677497
PGC: 109854903
NVI: 100114881(SdhD)
TCA: 660493
DPA: 109540617
PMAC: 106708740
PRAP: 111001408
PXY: 105395521
DNX: 107166097
ZNE: 110830762
FCD: 110848436
TUT: 107366938
CEL: CELE_F33A8.5(sdhd-1)
CBR: CBG02978(Cbr-sdhd-1)
BMY: Bm1_35660
TSP: Tsp_00425
CRG: 105338659
MYI: 110466478
OBI: 106871739
SHX: MS3_07487
EPA: 110241109
ADF: 107335288
HMG: 100205518
AQU: 100633514
CRE: CHLREDRAFT_146346(SDH4)
APRO: F751_3513
SCE: YDR178W(SDH4) YLR164W(SHH4)
ERC: Ecym_4190
KMX: KLMA_50550(SDH4)
NCS: NCAS_0B03140(NCAS0B03140)
NDI: NDAI_0A01150(NDAI0A01150)
TPF: TPHA_0C02440(TPHA0C02440)
TBL: TBLA_0H01000(TBLA0H01000)
TDL: TDEL_0F05010(TDEL0F05010)
KAF: KAFR_0B06070(KAFR0B06070) KAFR_0H02020(KAFR0H02020)
PIC: PICST_35330(SDH5) PICST_90476(SDH4)
CAL: CAALFM_C103940WA(CaO19.4468) CAALFM_C505280CA(SDH4)
SLB: AWJ20_1350(SHH4)
NCR: NCU03031(tca-13)
NTE: NEUTE1DRAFT119188(NEUTE1DRAFT_119188)
MGR: MGG_00666
MAW: MAC_07488
MAJ: MAA_07462
CMT: CCM_00099
MBE: MBM_03493
ANI: AN0896.2
ANG: ANI_1_1886014(An01g13930)
ABE: ARB_01822
TVE: TRV_06423
PTE: PTT_07579
ZTR: MYCGRDRAFT_57478(SDH4)
SPO: SPBP23A10.16(sdh4)
CNE: CNB00800
CNB: CNBB4910
ABP: AGABI1DRAFT87403(SDH4)
ABV: AGABI2DRAFT195170(SDH4)
SLA: SERLADRAFT_471409(SDH4)
MGL: MGL_2021
DDI: DDB_G0278157(sdhD)
DFA: DFA_05926(sdhD)
SPAR: SPRG_04463
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Hirawake H, Taniwaki M, Tamura A, Amino H, Tomitsuka E, Kita K
  Title
Characterization of the human SDHD gene encoding the small subunit of cytochrome b (cybS) in mitochondrial succinate-ubiquinone oxidoreductase.
  Journal
Biochim Biophys Acta 1412:295-300 (1999)
DOI:10.1016/S0005-2728(99)00071-7
  Sequence
[hsa:6392]

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