KEGG   ORTHOLOGY: K00237Help
Entry
K00237                      KO                                     

Name
SDHD, SDH4
Definition
succinate dehydrogenase (ubiquinone) membrane anchor subunit
Pathway
ko00020  Citrate cycle (TCA cycle)
ko00190  Oxidative phosphorylation
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01120  Microbial metabolism in diverse environments
ko01130  Biosynthesis of antibiotics
ko01200  Carbon metabolism
ko04714  Thermogenesis
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05016  Huntington disease
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00148  Succinate dehydrogenase (ubiquinone)
Disease
H00034  Carcinoid
H01222  Cowden syndrome
H01510  Malignant paraganglioma
H02005  Mitochondrial complex II deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
 09160 Human Diseases
  09163 Neurodegenerative diseases
   05010 Alzheimer disease
    K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
   05012 Parkinson disease
    K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
   05016 Huntington disease
    K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
  09166 Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Central carbohydrate metabolism
    M00009  Citrate cycle (TCA cycle, Krebs cycle)
     K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
    M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
     K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
 Structural complex
  Energy metabolism
   ATP synthesis
    M00148  Succinate dehydrogenase (ubiquinone)
     K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
BRITE hierarchy
Other DBs
RN: R02164
COG: COG2142
Genes
HSA: 6392(SDHD)
PTR: 451547(SDHD)
PPS: 100975025(SDHD) 100992849
GGO: 101141433 101141792 101151822 109028866(SDHD)
PON: 100172275(SDHD)
NLE: 100584747(SDHD) 100590500 101178881
MCC: 106992278(SDHD) 711326(SDHD)
MCF: 102132064(SDHD)
CSAB: 103240581 103248461(SDHD)
RRO: 104677354(SDHD)
RBB: 108536453(SDHD)
CJC: 100413949(SDHD)
SBQ: 101028994(SDHD)
MMU: 66925(Sdhd)
RNO: 363061(Sdhd)
CGE: 100774657(Sdhd)
NGI: 103733879(Sdhd)
HGL: 101702014(Sdhd)
CCAN: 109699440(Sdhd)
CFA: 479438(SDHD)
ORO: 101369783(SDHD)
FCA: 101095280(SDHD) 111557658
PTG: 102952867(SDHD)
AJU: 106975241 106984276(SDHD)
BTA: 281481(SDHD)
BOM: 102281830(SDHD)
BIU: 109556917(SDHD)
CHX: 100860881(SDHD)
OAS: 101111485(SDHD) 780442 780772
SSC: 100048954(SDHD)
CFR: 102521513(SDHD)
CDK: 105094129(SDHD)
BACU: 103014249(SDHD)
LVE: 103087853(SDHD)
OOR: 101271681(SDHD) 101277363
ECB: 100629334(SDHD)
EPZ: 103565881(SDHD)
EAI: 106840217(SDHD)
MYB: 102259933(SDHD)
MYD: 102763784(SDHD)
HAI: 109388702(SDHD)
RSS: 109436603(SDHD)
PALE: 102885251(SDHD)
LAV: 100655924 100668090(SDHD)
TMU: 101348027
MDO: 100032261(SDHD)
SHR: 100916627(SDHD)
GGA: 419793(SDHD)
MGP: 104909347(SDHD)
CJO: 107324125(SDHD)
APLA: 101804599(SDHD)
ACYG: 106039722(SDHD)
GFR: 102032079(SDHD)
FAB: 107604174(SDHD)
PHI: 102105389(SDHD)
PMAJ: 107214401(SDHD)
CCW: 104692077(SDHD)
FPG: 101915216(SDHD)
FCH: 102046315(SDHD)
CLV: 102089042(SDHD)
EGZ: 104125935(SDHD)
ASN: 102375141(SDHD)
AMJ: 102571129(SDHD)
PSS: 102453028(SDHD)
CMY: 102934024(SDHD)
CPIC: 101931568(SDHD)
PVT: 110079388(SDHD)
PBI: 103052888(SDHD)
GJA: 107116139(SDHD)
XLA: 494586(sdhd.S) 496372(sdhd.L)
XTR: 394986(sdhd)
NPR: 108801745(SDHD)
DRE: 436762(sdhda) 445500(sdhdb)
IPU: 108277787(sdhd)
AMEX: 103030352(sdhd)
TRU: 101073558(sdhd)
LCO: 104940581(sdhd)
NCC: 104945632(sdhd)
MZE: 101471207(sdhd)
OLA: 101167814(sdhd)
XMA: 102225550(sdhd)
PRET: 103474368(sdhd)
NFU: 107380753(sdhd)
CSEM: 103377767(sdhd)
LCF: 108900022(sdhd)
HCQ: 109510914(sdhd)
BPEC: 110162000(sdhd)
ELS: 105024040(sdhd)
SFM: 108928640(sdhd)
LCM: 102347390(SDHD)
CMK: 103191157(sdhd)
CIN: 100180725
SPU: 588082
APLC: 110990396
SKO: 100371519
DME: Dmel_CG10219(SdhD)
DSI: Dsimw501_GD18356(Dsim_GD18356)
AAG: 5573489
AME: 725566
BIM: 100742104
BTER: 100650698
SOC: 105203611
AEC: 105150009
ACEP: 105625215
PBAR: 105432798
HST: 105183236
CFO: 105250939
LHU: 105677497
PGC: 109854903
NVI: 100114881(SdhD)
TCA: 660493
DPA: 109540617
PMAC: 106708740
PRAP: 111001408
PXY: 105395521
DNX: 107166097
ZNE: 110830762
FCD: 110848436
TUT: 107366938
CEL: CELE_F33A8.5(sdhd-1)
CBR: CBG02978(Cbr-sdhd-1)
BMY: Bm1_35660
TSP: Tsp_00425
CRG: 105338659
MYI: 110466478
OBI: 106871739
SHX: MS3_07487
EPA: 110241109
ADF: 107335288
HMG: 100205518
AQU: 100633514
CRE: CHLREDRAFT_146346(SDH4)
APRO: F751_3513
SCE: YDR178W(SDH4) YLR164W(SHH4)
ERC: Ecym_4190
KMX: KLMA_50550(SDH4)
NCS: NCAS_0B03140(NCAS0B03140)
NDI: NDAI_0A01150(NDAI0A01150)
TPF: TPHA_0C02440(TPHA0C02440)
TBL: TBLA_0H01000(TBLA0H01000)
TDL: TDEL_0F05010(TDEL0F05010)
KAF: KAFR_0B06070(KAFR0B06070) KAFR_0H02020(KAFR0H02020)
PIC: PICST_35330(SDH5) PICST_90476(SDH4)
CAL: CAALFM_C103940WA(CaO19.4468) CAALFM_C505280CA(SDH4)
SLB: AWJ20_1350(SHH4)
NCR: NCU03031(tca-13)
NTE: NEUTE1DRAFT119188(NEUTE1DRAFT_119188)
MGR: MGG_00666
MAW: MAC_07488
MAJ: MAA_07462
CMT: CCM_00099
MBE: MBM_03493
ANI: AN0896.2
ANG: ANI_1_1886014(An01g13930)
ABE: ARB_01822
TVE: TRV_06423
PTE: PTT_07579
ZTR: MYCGRDRAFT_57478(SDH4)
SPO: SPBP23A10.16(sdh4)
CNE: CNB00800
CNB: CNBB4910
ABP: AGABI1DRAFT87403(SDH4)
ABV: AGABI2DRAFT195170(SDH4)
SLA: SERLADRAFT_471409(SDH4)
MGL: MGL_2021
DDI: DDB_G0278157(sdhD)
DFA: DFA_05926(sdhD)
SPAR: SPRG_04463
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Hirawake H, Taniwaki M, Tamura A, Amino H, Tomitsuka E, Kita K
  Title
Characterization of the human SDHD gene encoding the small subunit of cytochrome b (cybS) in mitochondrial succinate-ubiquinone oxidoreductase.
  Journal
Biochim Biophys Acta 1412:295-300 (1999)
DOI:10.1016/S0005-2728(99)00071-7
  Sequence
[hsa:6392]

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