KEGG   ORTHOLOGY: K02087Help
Entry
K02087                      KO                                     

Name
CDK1, CDC2
Definition
cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
Pathway
ko04110  Cell cycle
ko04114  Oocyte meiosis
ko04115  p53 signaling pathway
ko04218  Cellular senescence
ko04540  Gap junction
ko04914  Progesterone-mediated oocyte maturation
ko05168  Herpes simplex infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05203  Viral carcinogenesis
Module
M00693  Cell cycle - G2/M transition
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
   04114 Oocyte meiosis
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
   04115 p53 signaling pathway
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
   04218 Cellular senescence
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
 09160 Human Diseases
  09161 Cancers
   05203 Viral carcinogenesis
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
  09167 Infectious diseases
   05168 Herpes simplex infection
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
   05169 Epstein-Barr virus infection
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
  09182 Protein families: genetic information processing
   03032 DNA replication proteins
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
   03036 Chromosome and associated proteins
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00693  Cell cycle - G2/M transition
     K02087  CDK1, CDC2; cyclin-dependent kinase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     K02087  CDK1, CDC2; cyclin-dependent kinase 1
    2.7.11.23  [RNA-polymerase]-subunit kinase
     K02087  CDK1, CDC2; cyclin-dependent kinase 1
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CMGC group
  CDK family
   K02087  CDK1, CDC2; cyclin-dependent kinase 1
DNA replication proteins [BR:ko03032]
 Eukaryotic Type
  DNA Replication Termination Factors
   Prevention of re-replication factors
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Kinases and associated factors
    K02087  CDK1, CDC2; cyclin-dependent kinase 1
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K02087  CDK1, CDC2; cyclin-dependent kinase 1
BRITE hierarchy
Other DBs
GO: 0004693 0008353
Genes
HSA: 983(CDK1)
PTR: 450481(CDK1)
PPS: 100996071(CDK1)
GGO: 101131389(CDK1)
PON: 100172184(CDK1)
NLE: 100585679(CDK1)
MCC: 699269(CDK1)
MCF: 101926839(CDK1) 102142638
CSAB: 103216148(CDK1)
RRO: 104663679(CDK1)
RBB: 108517523(CDK1)
CJC: 100408321(CDK1)
SBQ: 101035782(CDK1)
MMU: 12534(Cdk1)
RNO: 54237(Cdk1)
CGE: 100766716(Cdk1)
NGI: 103736117(Cdk1)
OCU: 100352863(CDK1)
TUP: 102489331(CDK1)
CFA: 100856079(CDK1)
AML: 100480564(CDK1)
UMR: 103667741(CDK1)
ORO: 101368443(CDK1)
FCA: 101101592(CDK1)
PTG: 102971079(CDK1)
AJU: 106989884(CDK1)
BTA: 281061(CDK1)
BOM: 102287071(CDK1)
BIU: 109553919(CDK1)
PHD: 102334559(CDK1)
CHX: 100861361(CDK1)
OAS: 100216432(CDK1) 106990114
SSC: 100155762(CDK1)
CFR: 102511381(CDK1)
CDK: 105093852(CDK1)
BACU: 103013678(CDK1)
LVE: 103091065(CDK1)
OOR: 101271295(CDK1)
ECB: 100072299(CDK1)
EPZ: 103559244(CDK1)
EAI: 106826179(CDK1)
MYB: 102255275(CDK1)
MYD: 102759739(CDK1)
HAI: 109380620(CDK1)
RSS: 109447390(CDK1) 109448224
PALE: 102885939(CDK1)
LAV: 100668529(CDK1)
TMU: 101344001
MDO: 100019039(CDK1)
SHR: 100924163(CDK1)
OAA: 100077655(CDK1)
GGA: 396252(CDK1)
MGP: 100549676(CDK1)
CJO: 107315682(CDK1)
APLA: 101803686(CDK1)
ACYG: 106031512(CDK1)
TGU: 100218430(CDK1)
GFR: 102034239(CDK1)
FAB: 101821925(CDK1)
PHI: 102104995(CDK1)
PMAJ: 107206660(CDK1)
CCW: 104690173(CDK1)
FPG: 101912565(CDK1)
FCH: 102058935(CDK1)
CLV: 102083762(CDK1)
EGZ: 104124647(CDK1)
AAM: 106486975(CDK1)
ASN: 102385352(CDK1)
AMJ: 102568663(CDK1)
PSS: 102448219(CDK1)
CMY: 102938229(CDK1)
CPIC: 101938813(CDK1)
ACS: 100562632(cdk1)
PVT: 110090865(CDK1)
PBI: 103058257(CDK1)
GJA: 107114753(CDK1)
XLA: 379785(cdk1.L) 380246(cdk1.S)
XTR: 394503(cdk1)
NPR: 108804782(CDK1)
DRE: 80973(cdk1)
CCAR: 109071041 109107870(cdk1)
IPU: 100528197(cdk1)
AMEX: 103047431(cdk1)
TRU: 101064374(cdk1)
LCO: 104936401(cdk1)
NCC: 104959894
MZE: 101478485(cdk1)
OLA: 100049478(cdk1)
XMA: 102227982(cdk1)
PRET: 103476652(cdk1)
NFU: 107376429(cdk1)
CSEM: 103386961(cdk1)
LCF: 108895329(cdk1)
HCQ: 109523199(cdk1)
BPEC: 110156805(cdk1)
SASA: 100196122(cdc2) 106607826
ELS: 105010542(cdk1)
SFM: 108939565(cdk1)
LCM: 102364653(CDK1)
CMK: 103180965(cdk1)
CIN: 101243133
APLC: 110973442
SKO: 100371627
DME: Dmel_CG5363(Cdk1)
DSI: Dsimw501_GD22264(Dsim_GD22264)
MDE: 101896041
AAG: 5570855
AME: 409590
BIM: 100749285
BTER: 100651604
SOC: 105197762
AEC: 105145471
ACEP: 105626336
PBAR: 105427585
HST: 105185671
CFO: 105253176
LHU: 105670789
PGC: 109856408
NVI: 100116857(Cdk1)
TCA: 656189
DPA: 109544046
NVL: 108563495
BMOR: 693060(Cdc2)
PMAC: 106718587
PRAP: 110999409
ZNE: 110836477
FCD: 110847918
CEL: CELE_T05G5.3(cdk-1)
CBR: CBG10007(Cbr-cdk-1)
BMY: Bm1_01435
TSP: Tsp_11762
CRG: 105346130
MYI: 110448550
OBI: 106880228
SHX: MS3_01917
EPA: 110232003
ADF: 107357319
HMG: 100203266
AQU: 100636755
SMIN: v1.2.000750.t1(symbB.v1.2.000750.t1)
PTI: PHATRDRAFT_51279(CDKA2)
TPS: THAPS_35387(cdc2)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Lindqvist A, Rodriguez-Bravo V, Medema RH
  Title
The decision to enter mitosis: feedback and redundancy in the mitotic entry network.
  Journal
J Cell Biol 185:193-202 (2009)
DOI:10.1083/jcb.200812045
  Sequence
[hsa:983]
Reference
PMID:3553962
  Authors
Lee MG, Nurse P
  Title
Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2.
  Journal
Nature 327:31-5 (1987)
DOI:10.1038/327031a0
  Sequence
[hsa:983]

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