KEGG   ORTHOLOGY: K02147Help
Entry
K02147                      KO                                     

Name
ATPeV1B, ATP6B
Definition
V-type H+-transporting ATPase subunit B
Pathway
ko00190  Oxidative phosphorylation
ko01100  Metabolic pathways
ko04145  Phagosome
ko04150  mTOR signaling pathway
ko04721  Synaptic vesicle cycle
ko04966  Collecting duct acid secretion
ko05110  Vibrio cholerae infection
ko05120  Epithelial cell signaling in Helicobacter pylori infection
ko05165  Human papillomavirus infection
ko05323  Rheumatoid arthritis
Module
M00160  V-type ATPase, eukaryotes
Disease
H00428  Distal renal tubular acidosis (RTA type 1)
H01573  Zimmermann-Laband syndrome (ZLS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
 09150 Organismal Systems
  09155 Excretory system
   04966 Collecting duct acid secretion
    K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
  09156 Nervous system
   04721 Synaptic vesicle cycle
    K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
 09160 Human Diseases
  09162 Immune diseases
   05323 Rheumatoid arthritis
    K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
  09167 Infectious diseases
   05110 Vibrio cholerae infection
    K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
   05165 Human papillomavirus infection
    K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
KEGG modules [BR:ko00002]
 Structural complex
  Energy metabolism
   ATP synthesis
    M00160  V-type ATPase, eukaryotes
     K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
BRITE hierarchy
Other DBs
COG: COG1156
TC: 3.A.2.2
Genes
HSA: 525(ATP6V1B1) 526(ATP6V1B2)
PTR: 464033(ATP6V1B2) 470401(ATP6V1B1)
PPS: 100976103(ATP6V1B1) 100986037(ATP6V1B2)
GGO: 101125715(ATP6V1B2) 101146808(ATP6V1B1)
PON: 100173673(ATP6V1B2) 100449696(ATP6V1B1)
NLE: 100581139(ATP6V1B1) 100589839(ATP6V1B2)
MCC: 703646(ATP6V1B1) 705605(ATP6V1B2)
MCF: 101925257(ATP6V1B2) 102139650(ATP6V1B1)
CSAB: 103215418(ATP6V1B2) 103220084(ATP6V1B1)
RRO: 104661334(ATP6V1B1) 104672558(ATP6V1B2)
RBB: 108524578(ATP6V1B1) 108532586(ATP6V1B2)
CJC: 100400819(ATP6V1B1) 100405540(ATP6V1B2)
SBQ: 101043270(ATP6V1B1) 101051309(ATP6V1B2)
MMU: 110935(Atp6v1b1) 11966(Atp6v1b2)
RNO: 117596(Atp6v1b2) 312488(Atp6v1b1)
CGE: 100756094(Atp6v1b1) 100774665(Atp6v1b2)
NGI: 103726958(Atp6v1b1) 103747668(Atp6v1b2)
HGL: 101704199(Atp6v1b2) 101720999(Atp6v1b1)
CCAN: 109696641(Atp6v1b2) 109697377(Atp6v1b1)
OCU: 100341367(ATP6V1B2) 100348723(ATP6V1B1)
TUP: 102489634(ATP6V1B1) 102493700(ATP6V1B2)
CFA: 474628(ATP6V1B1) 486137(ATP6V1B2)
AML: 100463698(ATP6V1B2) 100482823(ATP6V1B1)
UMR: 103671376(ATP6V1B1) 103676707(ATP6V1B2)
ORO: 101379692(ATP6V1B2) 101386479(ATP6V1B1)
FCA: 101092601(ATP6V1B2) 101098295(ATP6V1B1)
PTG: 102952642(ATP6V1B1) 102968426(ATP6V1B2)
AJU: 106967713(ATP6V1B1) 106971859(ATP6V1B2)
BTA: 338059(ATP6V1B1) 338082(ATP6V1B2)
BOM: 102273812(ATP6V1B2) 102274358(ATP6V1B1)
BIU: 109563093(ATP6V1B2) 109565515(ATP6V1B1)
PHD: 102328221(ATP6V1B1) 102343769(ATP6V1B2)
CHX: 102185090(ATP6V1B1) 102191135(ATP6V1B2)
OAS: 101107683(ATP6V1B1) 494439(ATP6V1B2)
SSC: 100523368(ATP6V1B1) 106504095(ATP6V1B2)
CFR: 102508007(ATP6V1B1) 102519938(ATP6V1B2)
CDK: 105102115(ATP6V1B1) 105102893(ATP6V1B2)
LVE: 103084496(ATP6V1B2) 103089161(ATP6V1B1)
OOR: 101282169(ATP6V1B1) 101285856(ATP6V1B2)
ECB: 100050282(ATP6V1B1) 100055525(ATP6V1B2)
EPZ: 103561145(ATP6V1B2) 103564546(ATP6V1B1)
EAI: 106828308(ATP6V1B1) 106831206(ATP6V1B2)
MYB: 102246459(ATP6V1B2) 102248043(ATP6V1B1)
MYD: 102759282(ATP6V1B2) 102767647(ATP6V1B1)
HAI: 109382402(ATP6V1B2) 109385374(ATP6V1B1)
RSS: 109438717(ATP6V1B1) 109440660 109440783 109441612 109454218(ATP6V1B2)
PALE: 102887242(ATP6V1B1) 102893119(ATP6V1B2)
LAV: 100666469(ATP6V1B1) 100666832(ATP6V1B2)
MDO: 100033071(ATP6V1B2) 103106012(ATP6V1B1)
SHR: 100930744(ATP6V1B2) 100931454(ATP6V1B1)
OAA: 100073907(ATP6V1B2)
GGA: 395497(ATP6V1B2)
MGP: 100544578(ATP6V1B2)
CJO: 107306809(ATP6V1B1) 107323759(ATP6V1B2)
APLA: 101794271(ATP6V1B1) 101805143(ATP6V1B2)
ACYG: 106043177(ATP6V1B1) 106044427(ATP6V1B2)
TGU: 100219912(ATP6V1B2)
GFR: 102037079(ATP6V1B2) 102038205(ATP6V1B1)
FAB: 101812801(ATP6V1B1) 101814698(ATP6V1B2)
PHI: 102106704(ATP6V1B2) 102109868(ATP6V1B1)
PMAJ: 107213978(ATP6V1B2)
CCW: 104694843(ATP6V1B2)
FPG: 101917036(ATP6V1B2) 101922086(ATP6V1B1)
FCH: 102049411(ATP6V1B2) 102054316(ATP6V1B1)
CLV: 102088407(ATP6V1B1) 102097239(ATP6V1B2)
EGZ: 104127852(ATP6V1B2) 104135375
AAM: 106482765(ATP6V1B1) 106498830(ATP6V1B2)
ASN: 102370877(ATP6V1B2) 102370909(ATP6V1B1)
AMJ: 102567970(ATP6V1B1) 102576299(ATP6V1B2) 109285913
PSS: 102443523(ATP6V1B2) 102448978(ATP6V1B1)
CMY: 102933125(ATP6V1B2) 102947019(ATP6V1B1)
CPIC: 101932017(ATP6V1B2) 101952044(ATP6V1B1)
ACS: 100554895(atp6v1b2) 100561536
PVT: 110079830(ATP6V1B1) 110089337(ATP6V1B2)
PBI: 103057824(ATP6V1B1) 103062478(ATP6V1B2)
GJA: 107112675(ATP6V1B1) 107115365(ATP6V1B2)
XLA: 108711609 380305(atp6v1b2.S) 779272(atp6v1b1.L)
XTR: 100135740(atp6v1b1) 779628(atp6v1b2)
NPR: 108790249(ATP6V1B1) 108795037(ATP6V1B2)
DRE: 359839(atp6v1ba) 359840(atp6v1b2)
IPU: 108270233(ATP6V1B2) 108277294(ATP6V1B2)
TRU: 101072524 101074564(atp6v1b2) 105418299
LCO: 104929394 104935770(atp6v1b2)
OLA: 101163388 101173571(atp6v1ba)
CSEM: 103387792 103389142(atp6v1b2)
HCQ: 109523151
BPEC: 110169129
SASA: 100136392(vat1) 100196724(vatb2) 106563054
SFM: 108918108 108929544(atp6v1b2)
LCM: 102356745(ATP6V1B2) 102366641(ATP6V1B1)
CIN: 100186335
SPU: 589417
APLC: 110979848
SKO: 100372746
DME: Dmel_CG17369(Vha55)
DSI: Dsimw501_GD20555(Dsim_GD20555)
MDE: 101893693
AAG: 5567068
AME: 551721
BIM: 100744394
BTER: 100644823
SOC: 105203019
AEC: 105146530
ACEP: 105624815
PBAR: 105430086
HST: 105184850
CFO: 105254536
LHU: 105672561
PGC: 109854683
NVI: 100116861
TCA: 656208
DPA: 109545487
NVL: 108563306
BMOR: 100037422
PMAC: 106717345
PRAP: 110998939
DNX: 107165980
ZNE: 110839292
FCD: 110857993
TUT: 107359151
CEL: CELE_F20B6.2(vha-12) CELE_Y110A7A.12(spe-5)
CBR: CBG10811(Cbr-tag-300) CBG14362(Cbr-vha-12)
BMY: Bm1_12010
TSP: Tsp_06498
CRG: 105328999
MYI: 110451701
OBI: 106870500
SHX: MS3_02343
EPA: 110238546
ADF: 107348392
HMG: 100203652
AQU: 100639470
ATH: AT1G20260(VAB3) AT1G76030(VAB1) AT4G38510(VAB2)
CIT: 102617516
LJA: Lj0g3v0158079.1(Lj0g3v0158079.1) Lj0g3v0302619.1(Lj0g3v0302619.1) Lj0g3v0302619.2(Lj0g3v0302619.2) Lj0g3v0302619.3(Lj0g3v0302619.3) Lj5g3v2246070.1(Lj5g3v2246070.1) Lj5g3v2246070.2(Lj5g3v2246070.2)
FVE: 101293058
PPER: 18768303
PMUM: 103334857
PAVI: 110753753
CSV: 101211838
CMO: 103490265
MCHA: 111007788
DCR: 108227625
BVG: 104893069
SOE: 110791113
DOSA: Os01t0711000-01(Os01g0711000) Os06t0568200-01(Os06g0568200)
ATS: 109740398(LOC109740398) 109768110(LOC109768110) 109775652(LOC109775652) 109776688(LOC109776688)
DCT: 110110267
ATR: 18426589
CRE: CHLREDRAFT_126382(ATPvB)
APRO: F751_1409
SCE: YBR127C(VMA2)
ERC: Ecym_3439
KMX: KLMA_20708(VMA2)
NCS: NCAS_0I00920(NCAS0I00920)
NDI: NDAI_0A08100(NDAI0A08100)
TPF: TPHA_0A03440(TPHA0A03440)
TBL: TBLA_0C02220(TBLA0C02220)
TDL: TDEL_0C05260(TDEL0C05260)
KAF: KAFR_0D02530(KAFR0D02530)
PIC: PICST_48891(VMA2)
CAL: CAALFM_CR05780WA(VMA2)
SLB: AWJ20_2960(VMA2)
NCR: NCU08515(vma-2)
NTE: NEUTE1DRAFT117258(NEUTE1DRAFT_117258)
MGR: MGG_03244
MAW: MAC_05655
CMT: CCM_05187
BFU: BCIN_04g04820(Bcvma2)
MBE: MBM_08986
ANI: AN6232.2
ANG: ANI_1_276024(An02g02020)
ABE: ARB_04806
TVE: TRV_03783
PTE: PTT_12738
SPO: SPAC637.05c(vma2)
CNE: CNI01180
CNB: CNBH1120
ABP: AGABI1DRAFT114009(AGABI1DRAFT_114009)
ABV: AGABI2DRAFT193846(AGABI2DRAFT_193846)
MGL: MGL_3123
DDI: DDB_G0277401(vatB)
DFA: DFA_07259(vatB)
EHI: EHI_189850(18.t00032)
PYO: PY17X_1005200(PY05102)
PCB: PCHAS_100470(PC001225.02.0)
TAN: TA08450
TPV: TP04_0441
BBO: BBOV_II001490(18.m06115)
CPV: cgd8_1670
SMIN: v1.2.009104.t1(symbB.v1.2.009104.t1) v1.2.009105.t1(symbB.v1.2.009105.t1)
TPS: THAPSDRAFT_40522(VAT1)
SPAR: SPRG_07890
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Syntichaki P, Samara C, Tavernarakis N
  Title
The vacuolar H+ -ATPase mediates intracellular acidification required for neurodegeneration in C. elegans.
  Journal
Curr Biol 15:1249-54 (2005)
DOI:10.1016/j.cub.2005.05.057
  Sequence
Reference
PMID:2527371
  Authors
Sudhof TC, Fried VA, Stone DK, Johnston PA, Xie XS
  Title
Human endomembrane H+ pump strongly resembles the ATP-synthetase of Archaebacteria.
  Journal
Proc Natl Acad Sci U S A 86:6067-71 (1989)
DOI:10.1073/pnas.86.16.6067
  Sequence
[hsa:525]
Reference
PMID:7706273
  Authors
Lee BS, Underhill DM, Crane MK, Gluck SL
  Title
Transcriptional regulation of the vacuolar H(+)-ATPase B2 subunit gene in differentiating THP-1 cells.
  Journal
J Biol Chem 270:7320-9 (1995)
DOI:10.1074/jbc.270.13.7320
  Sequence
[hsa:526]

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