KEGG   ORTHOLOGY: K02178Help
Entry
K02178                      KO                                     

Name
BUB1
Definition
checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
Pathway
ko04110  Cell cycle
ko04111  Cell cycle - yeast
ko04113  Meiosis - yeast
ko04114  Oocyte meiosis
ko04914  Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K02178  BUB1; checkpoint serine/threonine-protein kinase
   04111 Cell cycle - yeast
    K02178  BUB1; checkpoint serine/threonine-protein kinase
   04113 Meiosis - yeast
    K02178  BUB1; checkpoint serine/threonine-protein kinase
   04114 Oocyte meiosis
    K02178  BUB1; checkpoint serine/threonine-protein kinase
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    K02178  BUB1; checkpoint serine/threonine-protein kinase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K02178  BUB1; checkpoint serine/threonine-protein kinase
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K02178  BUB1; checkpoint serine/threonine-protein kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K02178  BUB1; checkpoint serine/threonine-protein kinase
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  BUB family
   K02178  BUB1; checkpoint serine/threonine-protein kinase
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Core SAC proteins
     K02178  BUB1; checkpoint serine/threonine-protein kinase
BRITE hierarchy
Other DBs
COG: COG0515
Genes
HSA: 699(BUB1)
PTR: 459484(BUB1)
PPS: 100972278(BUB1)
GGO: 101147780(BUB1)
PON: 100439295(BUB1)
NLE: 100601563(BUB1) 100604441
MCC: 696598(BUB1)
MCF: 102133677(BUB1)
CSAB: 103241243(BUB1)
RRO: 104672448(BUB1)
RBB: 108529804(BUB1)
CJC: 100396829(BUB1)
SBQ: 101044372(BUB1)
MMU: 12235(Bub1)
RNO: 296137(Bub1)
CGE: 100772514(Bub1)
NGI: 103746937(Bub1) 108491617
HGL: 101724275(Bub1)
CCAN: 109683617 109702994(Bub1)
OCU: 100352234(BUB1)
TUP: 102498805(BUB1)
CFA: 100682599(BUB1)
AML: 100475509(BUB1)
UMR: 103671515(BUB1)
ORO: 101378636(BUB1)
FCA: 101085035(BUB1)
PTG: 102957582(BUB1)
AJU: 106976032(BUB1)
BTA: 514777(BUB1)
BOM: 102270961 102278310(BUB1)
BIU: 109565713(BUB1)
PHD: 102340642(BUB1)
CHX: 102172729(BUB1)
OAS: 101117404(BUB1)
SSC: 100627208(BUB1)
CFR: 102518925(BUB1)
CDK: 105092966(BUB1)
BACU: 103001566(BUB1)
LVE: 103070088(BUB1)
OOR: 101273035(BUB1)
ECB: 100064049(BUB1)
EPZ: 103552647(BUB1)
EAI: 106838537(BUB1)
MYB: 102256429(BUB1)
MYD: 102755202(BUB1)
HAI: 109393527(BUB1)
RSS: 109444458(BUB1)
PALE: 102891038(BUB1)
LAV: 100660153(BUB1)
TMU: 101348478
MDO: 100033212(BUB1)
SHR: 100931451(BUB1)
OAA: 100073976(BUB1)
GGA: 421226(BUB1)
MGP: 100542983(BUB1)
CJO: 107310732(BUB1)
APLA: 101803695(BUB1)
ACYG: 106042248(BUB1)
TGU: 100227797(BUB1)
GFR: 102041853(BUB1)
FAB: 101819085(BUB1)
PHI: 102099698(BUB1)
PMAJ: 107202318(BUB1)
CCW: 104691552(BUB1)
FPG: 101918279(BUB1)
FCH: 102052065(BUB1)
CLV: 102091159(BUB1)
EGZ: 104128133(BUB1)
AAM: 106494262(BUB1)
ASN: 102383453(BUB1)
AMJ: 102562842(BUB1)
PSS: 102459264(BUB1)
CMY: 102938971(BUB1)
CPIC: 101948684(BUB1)
ACS: 100559298(bub1)
PVT: 110087025(BUB1)
PBI: 103064193(BUB1)
GJA: 107114594(BUB1)
XLA: 398234(bub1.L)
XTR: 780291(bub1)
NPR: 108800990(BUB1) 108801001
DRE: 100307076(bub1)
SRX: 107709934(bub1)
SANH: 107675052(bub1)
SGH: 107560476(bub1)
IPU: 108255074(bub1)
AMEX: 103021907(bub1)
TRU: 101077348(bub1)
LCO: 104938881(bub1)
OLA: 101169751(bub1)
XMA: 102217306(bub1)
PRET: 103457093(bub1)
NFU: 107378199(bub1) 107387549
CSEM: 103381343(bub1)
LCF: 108882242(bub1)
HCQ: 109524807(bub1)
BPEC: 110164282(bub1)
SASA: 100306849(bub1) 106607702
ELS: 105017850(bub1)
SFM: 108942627(bub1)
LCM: 102349821(BUB1)
CMK: 103178944(bub1)
CIN: 100182383
SPU: 577602
APLC: 110979487
SKO: 100369016
DME: Dmel_CG14030(Bub1) Dmel_CG7838(BubR1)
DSI: Dsimw501_GD10345(Dsim_GD10345) Dsimw501_GD23333(Dsim_GD23333)
AME: 726325(GB13899)
BIM: 100745706
BTER: 100642479
SOC: 105201817
AEC: 105147766
ACEP: 105620478
PBAR: 105429548
HST: 105191067
CFO: 105249225
LHU: 105673740
PGC: 109856947
NVI: 100679995
TCA: 660046(Bub1)
DPA: 109538669
NVL: 108562625
BMOR: 101742536
PMAC: 106717449
PRAP: 110996936
PXY: 105387080
API: 100160600
DNX: 107165863
ZNE: 110835515
CEL: CELE_R06C7.8(bub-1)
CBR: CBG09940(Cbr-bub-1) CBG21913
BMY: Bm1_47200
TSP: Tsp_01159
CRG: 105330598
MYI: 110449875
ADF: 107334052
HMG: 100198524
AQU: 105312288
ATH: AT2G20635 AT2G33560(BUBR1)
LJA: Lj0g3v0069309.1(Lj0g3v0069309.1) Lj0g3v0073239.1(Lj0g3v0073239.1)
DOSA: Os02t0193600-01(Os02g0193600) Os07t0508500-01(Os07g0508500)
ATS: 109744408(LOC109744408) 109754853(LOC109754853)
PPP: 112273310
SCE: YGR188C(BUB1)
ERC: Ecym_8210
KMX: KLMA_40284(BUB1)
NCS: NCAS_0A07080(NCAS0A07080) NCAS_0D01920(NCAS0D01920)
NDI: NDAI_0D02140(NDAI0D02140)
TPF: TPHA_0J03180(TPHA0J03180)
TBL: TBLA_0B06620(TBLA0B06620)
TDL: TDEL_0E04680(TDEL0E04680)
KAF: KAFR_0K00880(KAFR0K00880)
CAL: CAALFM_C403120CA(BUB1)
CAUR: QG37_04586
SLB: AWJ20_1635(BUB1) AWJ20_1636(MAD3)
NCR: NCU10043
NTE: NEUTE1DRAFT90495(NEUTE1DRAFT_90495)
MGR: MGG_14329
MAW: MAC_04593
MAJ: MAA_00231
CMT: CCM_06660
MBE: MBM_01282
ANI: AN3946.2
ANG: ANI_1_1694094(An11g02000)
ABE: ARB_07905
TVE: TRV_04131
PTE: PTT_10915
SPO: SPCC1322.12c(bub1)
CNE: CNG03850
CNB: CNBG0900
ABP: AGABI1DRAFT75445(AGABI1DRAFT_75445)
ABV: AGABI2DRAFT201858(AGABI2DRAFT_201858)
MGL: MGL_3773
DDI: DDB_G0292676(bub1)
DFA: DFA_07867(bub1)
CPV: cgd7_2000
SPAR: SPRG_09747
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Tang Z, Shu H, Oncel D, Chen S, Yu H
  Title
Phosphorylation of Cdc20 by Bub1 provides a catalytic mechanism for APC/C inhibition by the spindle checkpoint.
  Journal
Mol Cell 16:387-97 (2004)
DOI:10.1016/j.molcel.2004.09.031
  Sequence
[hsa:699]
Reference
  Authors
Kitajima TS, Hauf S, Ohsugi M, Yamamoto T, Watanabe Y
  Title
Human Bub1 defines the persistent cohesion site along the mitotic chromosome by affecting Shugoshin localization.
  Journal
Curr Biol 15:353-9 (2005)
DOI:10.1016/j.cub.2004.12.044
  Sequence
[hsa:699]
Reference
  Authors
Klebig C, Korinth D, Meraldi P
  Title
Bub1 regulates chromosome segregation in a kinetochore-independent manner.
  Journal
J Cell Biol 185:841-58 (2009)
DOI:10.1083/jcb.200902128
  Sequence
[hsa:699]

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