KEGG   ORTHOLOGY: K02261Help
Entry
K02261                      KO                                     

Name
COX2
Definition
cytochrome c oxidase subunit 2
Pathway
ko00190  Oxidative phosphorylation
ko01100  Metabolic pathways
ko04260  Cardiac muscle contraction
ko04714  Thermogenesis
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05016  Huntington disease
Module
M00154  Cytochrome c oxidase
Disease
H01368  Cytochrome c oxidase (COX) deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K02261  COX2; cytochrome c oxidase subunit 2
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K02261  COX2; cytochrome c oxidase subunit 2
  09159 Environmental adaptation
   04714 Thermogenesis
    K02261  COX2; cytochrome c oxidase subunit 2
 09160 Human Diseases
  09163 Neurodegenerative diseases
   05010 Alzheimer disease
    K02261  COX2; cytochrome c oxidase subunit 2
   05012 Parkinson disease
    K02261  COX2; cytochrome c oxidase subunit 2
   05016 Huntington disease
    K02261  COX2; cytochrome c oxidase subunit 2
  09166 Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K02261  COX2; cytochrome c oxidase subunit 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K02261  COX2; cytochrome c oxidase subunit 2
KEGG modules [BR:ko00002]
 Structural complex
  Energy metabolism
   ATP synthesis
    M00154  Cytochrome c oxidase
     K02261  COX2; cytochrome c oxidase subunit 2
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Cytochrome c oxidase
    K02261  COX2; cytochrome c oxidase subunit 2
BRITE hierarchy
Other DBs
COG: COG1622
TC: 3.D.4.11 3.D.4.7 3.D.4.8
Genes
HSA: 4513(COX2)
PTR: 807864(COX2)
PPS: 807874(COX2)
GGO: 6742682(COX2)
PON: 808475(COX2)
NLE: 16545238(COX2)
MCC: 2846628(COX2)
MCF: 7857740(COX2)
CSAB: 4097491(COX2)
RRO: 4171537(COX2)
RBB: 10549370(COX2)
CJC: 22203903(COX2)
SBQ: 13228914(COX2)
MMU: 17709(COX2)
RNO: 26198(COX2)
CGE: 3979186(COX2)
NGI: 15088426(COX2)
HGL: 10201212(COX2)
CCAN: 31082906(COX2)
OCU: 808233(COX2)
CFA: 804479(COX2)
AML: 5179728(COX2)
UMR: 804870(COX2)
FCA: 807936(COX2)
AJU: 2654015(COX2)
BTA: 3283880(COX2)
BOM: 22161769(COX2)
BIU: 2885980(COX2)
PHD: 3703619(COX2)
CHX: 1485859(COX2)
OAS: 808252(COX2)
SSC: 808504(COX2)
CFR: 5326224(COX2)
CDK: 5618959(COX2)
LVE: 3802095(COX2)
OOR: 18982983(COX2)
ECB: 807845(COX2)
EPZ: 19019450(COX2)
EAI: 808064(COX2)
MYB: 20964695(COX2)
MYD: 22203917(COX2)
HAI: 13539868(COX2)
PALE: 17963494(COX2)
LAV: 808790(COX2)
MDO: 3074663(COX2)
SHR: 13826435(COX2)
OAA: 808709(COX2)
GGA: 807635(COX2)
MGP: 5848004(COX2)
CJO: 804666(COX2)
APLA: 5405812(COX2)
TGU: 3950793(COX2)
FAB: 16027875(COX2)
PHI: 9480995(COX2)
PMAJ: 22974846(COX2)
CCW: 20160630(COX2)
FPG: 808592(COX2)
FCH: 23808612(COX2)
CLV: 8889998(COX2)
EGZ: 18985250(COX2)
ASN: 806139(COX2)
AMJ: 808245(COX2)
PSS: 2943122(COX2)
CMY: 808646(COX2)
CPIC: 18982997(COX2)
ACS: 6385975(COX2)
PVT: 3338350(CO2)
GJA: 26044429(COX2)
XLA: 2642081(COX2)
XTR: 3283495(COX2)
NPR: 24020214(COX2)
DRE: 140540(COX2)
SRX: 24419178(COX2)
SANH: 24419954(COX2)
SGH: 8382165(COX2)
CCAR: 807772(COX2)
IPU: 804875(COX2)
TRU: 805219(COX2)
TNG: BAE79220(COII)
LCO: 7095384(COX2)
NCC: 10752025(COX2)
MZE: 26037644(APK84_gp10)
OLA: 805431(COX2)
XMA: 6986206(COX2)
PRET: 19590712(COX2)
NFU: 7256399(COX2)
CSEM: 7996482(COX2)
LCF: 3703590(COX2)
HCQ: 14658013(COX2)
SASA: 808315(COX2)
ELS: 806650(COX2)
SFM: 3416107(COX2)
LCM: 808086(COX2)
CMK: 9385347(COX2)
BFO: COX2
CIN: 806119(COX2)
SPU: 2652720(COX2)
APLC: 3907676(COX2)
SKO: 3703602(COX2)
DME: COX2
DSE: COX2
DSI: COX2
DYA: COX2
MDE: 20358596(COX2)
AGA: COX2
AAG: 33307558(COX2)
CQU: COX2
SOC: 9977790(COX2)
LHU: 26408697(COX2)
TCA: 803826(COX2)
DPA: 109533061
BMOR: 809267(COX2)
DPL: AGL76300(COX2)
PMAC: 13080342(COX2)
PRAP: 11030479(COX2)
PXY: 20834447(COX2)
API: 7055876(COX2)
DNX: 17428410(COX2)
ZNE: 110840503 20004829(COX2)
DPX: AAD33232(COII)
TUT: 6164216(COX2)
CEL: COX2
CBR: COX2
NAI: 804828(COX2)
BMY: COX2
TSP: COX2
CRG: 808828(COX2)
LAK: C2G87_mgp13(COX2)
SMM: COX2
SHX: 4097442(COX2)
ADF: 17674594(COX2)
HMG: 6904233(COX2)
TAD: TradoM_p11(COX2)
AQU: 4794355(COX2)
ATH: ArthMp015(cox2)
BNA: 106361778 4237883(cox2-1) 4237884(cox2-2)
CPAP: 110820367 7441425(cox2)
CIT: 36487036(cox2)
GRA: 105762759 27429599(cox2)
GHI: 24679512(cox2)
EGR: 104419302
GMX: 100782702(COX2) 15308623(cox2)
VRA: 106760164
VAR: 108322296
CCAJ: 109814968
CAM: 101496649
LJA: Lj0g3v0062549.1(Lj0g3v0062549.1) Lj0g3v0175899.1(Lj0g3v0175899.1) Ljmtg3v0000870.1(Ljmitog3v0000870.1)
AIP: 107619623
MDM: 13630207(cox2)
PXB: 103935049
CSV: 11123901(cox2)
CMO: 107990889
MCHA: 111018435
CPEP: 111810906
RCU: 10221420(cox2)
HBR: 110639978
JRE: 108999735
VVI: 7498556(cox2)
SLY: 101264997
SPEN: 107030119
SOT: 107063149
NTA: 3205306(cox2)
NSY: 104227400 27214855(cox2)
NTO: 104091428
INI: 29082029(cox2)
SIND: 105179430
HAN: 110942618
LSV: 111911403
DCR: 108214800 12598549(cox2)
BVG: 809487(cox2)
SOE: 33876581(cox2)
NNU: 28482653(cox2)
OSA: 6450161(cox2)
DOSA: Os04t0343050-00(Os04g0343050)
OBR: 102710463
SBI: 4306043(cox2)
ZMA: 109944005
SITA: 111256055
PDA: 11542569(cox2)
MUS: 103974065
ATR: 110006799
PPP: 3989052(cox2)
CRE: CHLREDRAFT_190125(COX2B)
VCN: VOLCADRAFT_80299(cox2B)
OTA: OstapMp32(Cox2)
BPG: BathyMg00040(cox2)
MIS: MicpuN_mit21(cox2)
CSL: CospCoM_p09(cox2)
CVR: OJ20_p06(cox2)
APRO: ChprMp035(cox2)
GSL: JL72_p04(cox2)
CCP: ChcroMp04(cox2)
SCE: Q0250(COX2)
KLA: KllafMp06(COX2)
KMX: CRD48_mgp11(COX2)
VPO: VapofMp05(cox2)
CGR: CaglfMp11(cox2)
DHA: cox2
CAL: CaalfMp01(COX2)
YLI: YalifMp18(cox2)
CLUS: 16792604(cox2)
NCR: NCU16028
SMP: SMAC_12689(cox2)
PAN: PoanfMp43(cox2)
FGR: GizefMp06(cox2)
ANG: Asnifp13(cox2)
SPO: ScpofMp10(cox2)
PYO: PY17X_1015300(PY01261)
PCB: PCHAS_101460(PC301550.00.0)
TAN: TA02790
TPV: TP01_0683
BBO: BBOV_IV010440(23.m05821)
SMIN: v1.2.011481.t1(symbB.v1.2.011481.t1) v1.2.011481.t2(symbB.v1.2.011481.t2)
PSOJ: PhsooMp05(cox2)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Rahman S, Taanman JW, Cooper JM, Nelson I, Hargreaves I, Meunier B, Hanna MG, Garcia JJ, Capaldi RA, Lake BD, Leonard JV, Schapira AH
  Title
A missense mutation of cytochrome oxidase subunit II causes defective assembly and myopathy.
  Journal
Am J Hum Genet 65:1030-9 (1999)
DOI:10.1086/302590
  Sequence
[hsa:4513]

DBGET integrated database retrieval system