KEGG   ORTHOLOGY: K02263Help
Entry
K02263                      KO                                     

Name
COX4
Definition
cytochrome c oxidase subunit 4
Pathway
ko00190  Oxidative phosphorylation
ko01100  Metabolic pathways
ko04260  Cardiac muscle contraction
ko04714  Thermogenesis
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko05010  Alzheimer's disease
ko05012  Parkinson's disease
ko05016  Huntington's disease
Module
M00154  Cytochrome c oxidase
Disease
H00920  Exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial hyperostosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Energy metabolism
   00190 Oxidative phosphorylation
    K02263  COX4; cytochrome c oxidase subunit 4
 Organismal Systems
  Circulatory system
   04260 Cardiac muscle contraction
    K02263  COX4; cytochrome c oxidase subunit 4
  Environmental adaptation
   04714 Thermogenesis
    K02263  COX4; cytochrome c oxidase subunit 4
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K02263  COX4; cytochrome c oxidase subunit 4
   05012 Parkinson's disease
    K02263  COX4; cytochrome c oxidase subunit 4
   05016 Huntington's disease
    K02263  COX4; cytochrome c oxidase subunit 4
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K02263  COX4; cytochrome c oxidase subunit 4
KEGG modules [BR:ko00002]
 Structural complex
  Energy metabolism
   ATP synthesis
    M00154  Cytochrome c oxidase
     K02263  COX4; cytochrome c oxidase subunit 4
BRITE hierarchy
Other DBs
TC: 3.D.4.11 3.D.4.8
Genes
HSA: 1327(COX4I1) 84701(COX4I2)
PTR: 454391(COX4I1) 469913(COX4I2)
PPS: 100969890 100980404 100992865
GGO: 101135385 101141650 101151536
PON: 100173464(COX4I1) 100448759
NLE: 100584639 100590535 100597359
MCC: 693811(COX4I1) 713095(COX4I2)
MCF: 102138538 102139855 102144280
CSAB: 103233412 103248003(COX4I2)
RRO: 104653722 104656020
MMU: 12857(Cox4i1) 84682(Cox4i2)
RNO: 29445(Cox4i1) 84683(Cox4i2)
OCU: 100327269(COX4I1) 100345745
CFA: 479623(COX4I1) 485825(COX4I2)
PTG: 102949741 102968374(COX4)
BTA: 281090(COX4I1) 618339(COX4I2)
ECB: 100053548(COX4I2) 100056171(COX4I1)
OAA: 100076685
GGA: 415826(COX4I1)
MGP: 100538694
CJO: 107319431
APLA: 101795065
ACYG: 106049252
TGU: 100222254
GFR: 102042855
FAB: 101822066
PHI: 102099643
PMAJ: 107210061
CCW: 104691910
FPG: 101917805
FCH: 102046687
CLV: 102098410
EGZ: 104133757
AAM: 106485951
AMJ: 102559681(COX4I2) 102574712
PVT: 110087070
PBI: 103060447
GJA: 107123752
XLA: 108719104 108720086 379593 444420(cox4i1.S) 444815(cox4i2.S) 447073
XTR: 100127750 549233(cox4i1) 549699(cox4i2)
DRE: 326975(cox4i1) 393776(cox4i2) 402880(cox4i1l)
IPU: 108256745 108264246(COX41) 108275904(COX42)
TRU: 101062555
SASA: 106562286(COX41) 106566437(COX42) 106572113(COX42) 106572114 106579596(COX42) 106587370(cox41)
CMK: 103175926
SPU: 591899
APLC: 110988390
SKO: 100370589
DME: Dmel_CG10396(COX4L) Dmel_CG10664(COX4)
DSI: Dsimw501_GD10371(Dsim_GD10371) Dsimw501_GD24236(Dsim_CoIV)
AAG: 5566092
AME: 412396(Cox4I1)
BIM: 100744616
BTER: 100642567
SOC: 105195100
AEC: 105154189
ACEP: 105622676
PBAR: 105434337
HST: 105186641
CFO: 105257159
LHU: 105671426
PGC: 109853666
NVI: 100117406(Cox4I1) 100121926
TCA: 655374(Cox4)
NVL: 108563345
API: 100158698
DNX: 107173504
ZNE: 110830830
FCD: 110855865
CEL: CELE_W09C5.8(cox-4)
CBR: CBG19770
BMY: Bm1_03920
TSP: Tsp_04478
CRG: 105347217
MYI: 110453644
OBI: 106882297
LAK: 106169530
SHX: MS3_07125
EPA: 110232462
ADF: 107352219
HMG: 100211497
SCE: YIL111W(COX5B) YNL052W(COX5A)
KMX: KLMA_30685(COX5B) KLMA_80159(COX5A)
NCS: NCAS_0B06400(NCAS0B06400) NCAS_0E00410(NCAS0E00410)
NDI: NDAI_0B03690(NDAI0B03690) NDAI_0I03090(NDAI0I03090)
TPF: TPHA_0E02560(TPHA0E02560) TPHA_0F01210(TPHA0F01210)
TBL: TBLA_0B05810(TBLA0B05810)
TDL: TDEL_0C04030(TDEL0C04030) TDEL_0D06100(TDEL0D06100)
KAF: KAFR_0J01530(KAFR0J01530) KAFR_0J02740(KAFR0J02740)
PIC: PICST_77110(COX5a)
CAL: CAALFM_C109030CA(COX5)
CAUR: QG37_02437
SLB: AWJ20_4857(COX5A)
NCR: NCU05457(cya-4)
NTE: NEUTE1DRAFT117482(NEUTE1DRAFT_117482)
MGR: MGG_03188
MAW: MAC_08051
MAJ: MAA_05317
CMT: CCM_07423
MBE: MBM_05495
ANI: AN2316.2
ANG: ANI_1_1404124(An14g04170)
ABE: ARB_07059
TVE: TRV_05994
PTE: PTT_13891
NPA: UCRNP2_79
SPO: SPCC338.10c(cox5)
CNE: CNK03240
CNB: CNBK0240
ABP: AGABI1DRAFT116514(COX4)
ABV: AGABI2DRAFT195535(COX4)
SLA: SERLADRAFT_476455(COX4)
MGL: MGL_1993
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Huttemann M, Kadenbach B, Grossman LI
  Title
Mammalian subunit IV isoforms of cytochrome c oxidase.
  Journal
Gene 267:111-23 (2001)
DOI:10.1016/S0378-1119(01)00385-7
  Sequence
[hsa:1327 84701]

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