KEGG   ORTHOLOGY: K03013
Entry
K03013                      KO                                     

Name
RPB5, POLR2E
Definition
DNA-directed RNA polymerases I, II, and III subunit RPABC1
Pathway
ko03020  RNA polymerase
ko04623  Cytosolic DNA-sensing pathway
ko05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery
    K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
   03400 DNA repair and recombination proteins
    K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
Transcription machinery [BR:ko03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Pol I, II, III common subunits
     K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
  RNA polymerase III system
   RNA polymerase III
    Pol I, II, III common subunits
     K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
  RNA polymerase I system
   RNA polymerase I
    Pol I, II, III common subunits
     K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
Other DBs
COG: COG2012
Genes
HSA: 5434(POLR2E)
PTR: 456359(POLR2E)
PPS: 100995503(POLR2E)
GGO: 101144214
PON: 100173829(POLR2E)
NLE: 100601807(POLR2E)
MCC: 721178(POLR2E)
MCF: 101865584(POLR2E)
CSAB: 103233592(POLR2E)
RRO: 104671426(POLR2E)
RBB: 108537888(POLR2E)
CJC: 100393628(POLR2E)
SBQ: 101051807(POLR2E)
MMU: 66420(Polr2e)
MCAL: 110303180(Polr2e)
MPAH: 110326739(Polr2e)
RNO: 690966(Polr2e)
MUN: 110551376(Polr2e)
CGE: 100754513(Polr2e)
NGI: 103737342(Polr2e)
HGL: 101709249(Polr2e)
CCAN: 109693677(Polr2e)
TUP: 102501578(POLR2E)
CFA: 611859(POLR2E)
VVP: 112935475(POLR2E)
AML: 100476981(POLR2E)
UMR: 103681776(POLR2E)
UAH: 113242719(POLR2E)
ORO: 101377466(POLR2E)
ELK: 111161893
FCA: 101095720(POLR2E)
PTG: 102950238(POLR2E)
PPAD: 109257738(POLR2E)
AJU: 106978086(POLR2E)
BTA: 512971(POLR2E)
BOM: 102279426(POLR2E)
BIU: 109561974(POLR2E)
BBUB: 102403834(POLR2E)
CHX: 102187213(POLR2E)
OAS: 101116826(POLR2E)
SSC: 100623333(POLR2E)
CFR: 102516640(POLR2E)
CDK: 105104119(POLR2E)
BACU: 103001195(POLR2E)
LVE: 103071766(POLR2E)
OOR: 101277900(POLR2E)
DLE: 111170494(POLR2E)
PCAD: 102992399(POLR2E)
ECB: 100065431(POLR2E)
EPZ: 103544865(POLR2E) 103545717
EAI: 106834192(POLR2E)
MYB: 102238881(POLR2E)
MYD: 102764259(POLR2E)
MNA: 107534567(POLR2E)
HAI: 109390606(POLR2E)
DRO: 112312635(POLR2E)
PALE: 102877935(POLR2E)
RAY: 107500947(POLR2E)
MJV: 108388790(POLR2E)
LAV: 100674866(POLR2E)
TMU: 101355270
MDO: 100015794(POLR2E)
SHR: 100927834(POLR2E)
PCW: 110223405(POLR2E)
GGA: 420103(POLR2E)
MGP: 100539270(POLR2E)
CJO: 107325463(POLR2E)
NMEL: 110388825(POLR2E)
APLA: 113845648(POLR2E)
ACYG: 106048192(POLR2E)
TGU: 100222301(POLR2E)
LSR: 110479133(POLR2E)
SCAN: 103821947(POLR2E)
GFR: 102045201(POLR2E)
FAB: 101817569(POLR2E)
PHI: 102113148(POLR2E)
PMAJ: 107215548(POLR2E)
CCAE: 111940245(POLR2E)
CCW: 104697062(POLR2E)
ETL: 114066397(POLR2E)
FPG: 101921128(POLR2E)
FCH: 102056021(POLR2E)
CLV: 102092010(POLR2E)
EGZ: 104127392(POLR2E)
NNI: 104016255(POLR2E)
ACUN: 113489347(POLR2E)
PADL: 103922942(POLR2E)
AAM: 106493538(POLR2E)
ASN: 102379403(POLR2E)
AMJ: 102570813(POLR2E)
PSS: 102443501(POLR2E)
CMY: 102942937(POLR2E)
CPIC: 101945038(POLR2E)
PVT: 110072605(POLR2E)
PBI: 103062569(POLR2E)
PMUR: 107282243(POLR2E)
TSR: 106545600(POLR2E)
GJA: 107107350(POLR2E)
XLA: 108696070 398968(polr2e.S)
XTR: 549227(polr2e)
NPR: 108789491(POLR2E)
DRE: 100330570(polr2ea) 445170(polr2eb)
IPU: 100528214(polr2e)
PHYP: 113533273(polr2e)
AMEX: 103030076(polr2e)
EEE: 113585969(polr2e)
TRU: 101073703(polr2e)
LCO: 104930510(polr2e)
NCC: 104948113(polr2e)
MZE: 101481657(polr2e)
ONL: 100534454(polr2e)
OLA: 101160893(polr2e)
XMA: 102219457(polr2e)
XCO: 114150818(polr2e)
PRET: 103463716(polr2e)
CVG: 107095298(polr2e)
NFU: 107393346(polr2e)
KMR: 108230783(polr2e)
ALIM: 106532518(polr2e)
AOCE: 111563470(polr2e)
CSEM: 103376763(polr2e)
POV: 109625471(polr2e)
LCF: 108879021(polr2e)
SDU: 111231964(polr2e)
SLAL: 111653741(polr2e)
HCQ: 109522892 109532430(polr2e)
BPEC: 110174071(polr2e)
MALB: 109966967(polr2e)
SASA: 106569462(RPAB1) 106573578(RPAB1)
ELS: 105011501(polr2e) 105022321
SFM: 108919890(polr2e)
LCM: 102365405(POLR2E)
CMK: 103189926(polr2e)
RTP: 109931451(polr2e) 109936183
BFO: 118411835
CIN: 100182874
SPU: 578317
APLC: 110977470
SKO: 100370922
DME: Dmel_CG11979(Rpb5)
DER: 6547281
DSE: 6608582
DSI: Dsimw501_GD15257(Dsim_GD15257)
DAN: 6495295
DSR: 110180017
DPE: 6597756
DWI: 6638219
DAZ: 108615064
DNV: 108654922
DHE: 111593196
DVI: 6635913
MDE: 101892048
LCQ: 111685554
AAG: 5574369
AME: 413110
BIM: 100748620
BTER: 100650619
CCAL: 108627711
OBB: 114873341
SOC: 105194466
MPHA: 105836042
AEC: 105148474
ACEP: 105619052
PBAR: 105428078
VEM: 105570369
HST: 105181521
DQU: 106749265
CFO: 105251888
LHU: 105670625
PGC: 109864206
OBO: 105275751
PCF: 106790943
NVI: 100115905
CSOL: 105362100
MDL: 103577910
TCA: 664433
DPA: 109534835
NVL: 108566499
BMOR: 101744152
BMAN: 114242560
PMAC: 106716578
PRAP: 111000657
HAW: 110370556
TNL: 113504420
PXY: 105392149
API: 100158973
DNX: 107164723
AGS: 114132029
RMD: 113553613
BTAB: 109042141
CLEC: 106668338
ZNE: 110827350
FCD: 110861498
PVM: 113817808
TUT: 107368911
CSCU: 111616440
PTEP: 107436586
CEL: CELE_H27M09.2(rpb-5)
CBR: CBG12745(Cbr-rpb-5)
TSP: Tsp_09788
PCAN: 112573589
CRG: 105330308
MYI: 110445162
OBI: 106874998
SHX: MS3_00822
EGL: EGR_01963
NVE: 5517395
AMIL: 114976917
PDAM: 113683360
SPIS: 111324083
DGT: 114535902
ATH: AT2G41340(RPB5D) AT3G22320(NRPB5) AT3G54490(RPB5E) AT3G57080(NRPE5) AT5G57980(RPB5C)
LJA: Lj0g3v0102149.1(Lj0g3v0102149.1) Lj1g3v4159160.1(Lj1g3v4159160.1) Lj2g3v0812020.1(Lj2g3v0812020.1) Lj2g3v0813200.1(Lj2g3v0813200.1) Lj4g3v3113140.1(Lj4g3v3113140.1) Lj4g3v3113140.2(Lj4g3v3113140.2)
DOSA: Os01t0805800-01(Os01g0805800) Os04t0487300-01(Os04g0487300) Os11t0143400-00(Os11g0143400) Os12t0139500-01(Os12g0139500)
ATS: 109731909(LOC109731909) 109745722(LOC109745722) 109746010(LOC109746010) 109766283(LOC109766283) 109782662(LOC109782662) 109782663(LOC109782663)
ZMA: 100193880 100273250(pco088367b) 100273995
CRE: CHLREDRAFT_151082(RPB5)
MNG: MNEG_9076
APRO: F751_1971
SCE: YBR154C(RPB5)
ERC: Ecym_5335
KMX: KLMA_40224(RPB5)
NCS: NCAS_0I02370(NCAS0I02370)
NDI: NDAI_0A06960(NDAI0A06960)
TPF: TPHA_0M00690(TPHA0M00690)
TBL: TBLA_0F01160(TBLA0F01160)
TDL: TDEL_0D05090(TDEL0D05090)
KAF: KAFR_0G01400(KAFR0G01400)
PIC: PICST_53602(RPB5)
CAL: CAALFM_C112820CA(CaO19.6340)
NCR: NCU05305
NTE: NEUTE1DRAFT145772(NEUTE1DRAFT_145772)
MGR: MGG_06083
SSCK: SPSK_01895
MAW: MAC_01379
MAJ: MAA_06406
CMT: CCM_03021
BFU: BCIN_06g07270(Bcrpb5)
MBE: MBM_01719
ANI: AN0752.2
ANG: ANI_1_1616014(An01g11950)
ABE: ARB_00066
TVE: TRV_01312
PTE: PTT_16482
SPO: SPAC23C4.15(rpb5)
CNE: CNA07710
CNB: CNBA7540
TASA: A1Q1_04969
ABP: AGABI1DRAFT114282(AGABI1DRAFT_114282)
ABV: AGABI2DRAFT191302(AGABI2DRAFT_191302)
MGL: MGL_3685
MRT: MRET_1660
DDI: DDB_G0291636(rpb5)
EHI: EHI_142090(200.t00008)
PCB: PCHAS_114010(PC000476.03.0)
TAN: TA10195
TPV: TP04_0911
BBO: BBOV_III009920(17.m07860)
CPV: cgd2_980
TGO: TGME49_240590(POLR2E)
SMIN: v1.2.005765.t1(symbB.v1.2.005765.t1)
TPS: THAPSDRAFT_268816(RPB5)
SPAR: SPRG_05117
BARC: AOA65_1693(rpoH)
BARB: AOA66_1727(rpoH)
VG: 18266059(pv_31) 19738591(007R) 30523590(BQ3484_79)
 » show all
Reference
PMID:9852112
  Authors
Kershnar E, Wu SY, Chiang CM
  Title
Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.
  Journal
J Biol Chem 273:34444-53 (1998)
DOI:10.1074/jbc.273.51.34444
  Sequence
[hsa:5434]
Reference
  Authors
Engel C, Sainsbury S, Cheung AC, Kostrewa D, Cramer P
  Title
RNA polymerase I structure and transcription regulation.
  Journal
Nature 502:650-5 (2013)
DOI:10.1038/nature12712
  Sequence
[sce:YBR154C]

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