KEGG   ORTHOLOGY: K04135Help
Entry
K04135                      KO                                     

Name
ADRA1A
Definition
adrenergic receptor alpha-1A
Pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04152  AMPK signaling pathway
ko04261  Adrenergic signaling in cardiomyocytes
ko04270  Vascular smooth muscle contraction
ko04970  Salivary secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K04135  ADRA1A; adrenergic receptor alpha-1A
   04022 cGMP - PKG signaling pathway
    K04135  ADRA1A; adrenergic receptor alpha-1A
   04152 AMPK signaling pathway
    K04135  ADRA1A; adrenergic receptor alpha-1A
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04135  ADRA1A; adrenergic receptor alpha-1A
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04135  ADRA1A; adrenergic receptor alpha-1A
   04270 Vascular smooth muscle contraction
    K04135  ADRA1A; adrenergic receptor alpha-1A
  09154 Digestive system
   04970 Salivary secretion
    K04135  ADRA1A; adrenergic receptor alpha-1A
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04135  ADRA1A; adrenergic receptor alpha-1A
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04135  ADRA1A; adrenergic receptor alpha-1A
BRITE hierarchy
Other DBs
GO: 0004937
Genes
HSA: 148(ADRA1A)
PTR: 472723(ADRA1A)
PPS: 100986808(ADRA1A)
GGO: 101132819(ADRA1A)
PON: 100447956(ADRA1A)
NLE: 100584192(ADRA1A)
MCC: 712509(ADRA1A)
MCF: 102126453(ADRA1A)
CSAB: 103215521(ADRA1A)
RRO: 104673950(ADRA1A)
RBB: 108537638(ADRA1A)
CJC: 100406276(ADRA1A)
SBQ: 101030040(ADRA1A)
MMU: 11549(Adra1a)
RNO: 29412(Adra1a)
CGE: 100758859(Adra1a)
NGI: 103732394(Adra1a)
HGL: 101712485(Adra1a)
CCAN: 109677899(Adra1a) 109678496
OCU: 100009237(ADRA1A)
TUP: 102485037(ADRA1A)
CFA: 403866(ADRA1A)
AML: 100479899(ADRA1A)
UMR: 103673285(ADRA1A)
ORO: 101384467(ADRA1A)
FCA: 101098375(ADRA1A)
PTG: 102958979(ADRA1A)
AJU: 106966540(ADRA1A)
BTA: 282134(ADRA1A)
BOM: 102265630(ADRA1A)
BIU: 109563154(ADRA1A)
PHD: 102324768(ADRA1A)
CHX: 102182788(ADRA1A)
OAS: 100169940(ADRA1A)
SSC: 100144471(ADRA1A)
CFR: 102516168(ADRA1A)
CDK: 105102306(ADRA1A)
BACU: 103018651(ADRA1A)
LVE: 103084741(ADRA1A)
OOR: 101280218(ADRA1A)
ECB: 100054461(ADRA1A)
EPZ: 103561082(ADRA1A)
EAI: 106834008(ADRA1A)
MYB: 102249717(ADRA1A)
MYD: 102767266(ADRA1A)
HAI: 109391742(ADRA1A)
RSS: 109436442(ADRA1A)
PALE: 102884516(ADRA1A)
LAV: 100668259(ADRA1A)
TMU: 101353836
MDO: 100017802(ADRA1A)
SHR: 100931456(ADRA1A)
OAA: 100680572(ADRA1A)
GGA: 428203(ADRA1A)
MGP: 100551391(ADRA1A)
CJO: 107323705(ADRA1A)
APLA: 101791607(ADRA1A)
ACYG: 106046252(ADRA1A)
TGU: 100227070(ADRA1A)
GFR: 102044365(ADRA1A)
FAB: 101813194(ADRA1A)
PHI: 102108110(ADRA1A)
PMAJ: 107213797(ADRA1A)
CCW: 104694822(ADRA1A)
FPG: 101923570(ADRA1A)
FCH: 102049705(ADRA1A)
CLV: 102094627(ADRA1A)
EGZ: 104123528(ADRA1A)
AAM: 106494221(ADRA1A)
ASN: 102381567 102386772(ADRA1A)
AMJ: 102557676(ADRA1A)
PSS: 102445281(ADRA1A)
CMY: 102933280(ADRA1A)
CPIC: 101931917(ADRA1A)
ACS: 100554316(adra1a)
PBI: 103048676(ADRA1A)
GJA: 107111679
XTR: 100492776(adra1a)
NPR: 108791007
DRE: 557259(adra1ab) 798498(adra1aa)
TRU: 101079659
HCQ: 109524941(adra1a) 109530086
ELS: 105024192
LCM: 102346555(ADRA1A) 102348461
CMK: 103191393(adra1a)
APLC: 110982610
ZNE: 110836209
FCD: 110846739
MYI: 110447814
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7815325
  Authors
Schwinn DA, Johnston GI, Page SO, Mosley MJ, Wilson KH, Worman NP, Campbell S, Fidock MD, Furness LM, Parry-Smith DJ, et al.
  Title
Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.
  Journal
J Pharmacol Exp Ther 272:134-42 (1995)
  Sequence
[hsa:148]

KEGG   ORTHOLOGY: K04136Help
Entry
K04136                      KO                                     

Name
ADRA1B
Definition
adrenergic receptor alpha-1B
Pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04261  Adrenergic signaling in cardiomyocytes
ko04270  Vascular smooth muscle contraction
ko04970  Salivary secretion
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K04136  ADRA1B; adrenergic receptor alpha-1B
   04022 cGMP - PKG signaling pathway
    K04136  ADRA1B; adrenergic receptor alpha-1B
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04136  ADRA1B; adrenergic receptor alpha-1B
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04136  ADRA1B; adrenergic receptor alpha-1B
   04270 Vascular smooth muscle contraction
    K04136  ADRA1B; adrenergic receptor alpha-1B
  09154 Digestive system
   04970 Salivary secretion
    K04136  ADRA1B; adrenergic receptor alpha-1B
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04136  ADRA1B; adrenergic receptor alpha-1B
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04136  ADRA1B; adrenergic receptor alpha-1B
BRITE hierarchy
Other DBs
GO: 0004937
Genes
HSA: 147(ADRA1B)
PTR: 736934(ADRA1B)
PPS: 106634821(ADRA1B)
GGO: 101142001(ADRA1B)
PON: 100435632(ADRA1B)
NLE: 100601962(ADRA1B)
MCC: 695106(ADRA1B)
MCF: 102126794(ADRA1B)
CSAB: 103244899(ADRA1B)
RRO: 104667499(ADRA1B)
RBB: 108537942(ADRA1B)
CJC: 100395759(ADRA1B)
SBQ: 101040811(ADRA1B)
MMU: 11548(Adra1b)
RNO: 24173(Adra1b)
CGE: 103160164(Adra1b)
NGI: 103724547(Adra1b)
HGL: 101700459(Adra1b)
CCAN: 109693948(Adra1b)
OCU: 100008731(ADRA1B)
TUP: 102486850(ADRA1B)
CFA: 403962(ADRA1B)
AML: 100482658(ADRA1B)
UMR: 103664794(ADRA1B)
ORO: 101371896(ADRA1B)
FCA: 101092238(ADRA1B)
PTG: 102954633(ADRA1B)
AJU: 106967619(ADRA1B)
BTA: 407140(ADRA1B)
BOM: 102285919(ADRA1B)
BIU: 109562263(ADRA1B)
PHD: 102320584(ADRA1B)
CHX: 102179850(ADRA1B)
OAS: 101114869(ADRA1B)
SSC: 100519931(ADRA1B)
CFR: 102505346(ADRA1B)
CDK: 105099901(ADRA1B)
BACU: 103009751(ADRA1B)
LVE: 103083430(ADRA1B)
OOR: 101273086(ADRA1B)
ECB: 100071055(ADRA1B)
EPZ: 103553004(ADRA1B)
EAI: 106832140(ADRA1B)
MYB: 102248047(ADRA1B)
MYD: 102772976(ADRA1B)
HAI: 109394203(ADRA1B)
RSS: 109451954(ADRA1B)
PALE: 102891192(ADRA1B)
LAV: 100675999(ADRA1B)
TMU: 101344094
MDO: 100025515(ADRA1B)
SHR: 100933002(ADRA1B)
OAA: 100074819(ADRA1B)
GGA: 373890(ADRA1B)
MGP: 100543635(ADRA1B)
CJO: 107320332(ADRA1B)
APLA: 101800019(ADRA1B)
ACYG: 106034421(ADRA1B)
TGU: 100218481(ADRA1B)
GFR: 102036518(ADRA1B)
FAB: 101814297(ADRA1B)
PHI: 102105127(ADRA1B)
PMAJ: 107210901(ADRA1B)
CCW: 104689636(ADRA1B)
FPG: 101920857(ADRA1B)
FCH: 102047141(ADRA1B)
CLV: 102097753(ADRA1B)
EGZ: 104133618(ADRA1B)
AAM: 106493600(ADRA1B)
ASN: 102372292(ADRA1B)
AMJ: 102565786(ADRA1B)
PSS: 102461525(ADRA1B)
CMY: 102933636(ADRA1B)
CPIC: 101947598(ADRA1B)
XLA: 108710187(adra1b.L) 108712448(adra1b.S)
XTR: 100488806(adra1b)
NPR: 108788121(ADRA1B)
DRE: 100149100(adra1ba) 492486(adra1bb)
IPU: 108269087 108278461(adra1b)
AMEX: 103033427(adra1b)
TRU: 101063369 101067265(adra1b)
PRET: 103471229(adra1b) 103476339
NFU: 107374377 107375503(adra1b)
CSEM: 103391200(adra1b) 103395768
BPEC: 110157659(adra1b) 110174997
ELS: 105011294(adra1b) 105029089
LCM: 102367148(ADRA1B)
CMK: 103186484(adra1b)
SPU: 762804
DPA: 109543734
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7815325
  Authors
Schwinn DA, Johnston GI, Page SO, Mosley MJ, Wilson KH, Worman NP, Campbell S, Fidock MD, Furness LM, Parry-Smith DJ, et al.
  Title
Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.
  Journal
J Pharmacol Exp Ther 272:134-42 (1995)
  Sequence
[hsa:147]

KEGG   ORTHOLOGY: K04138Help
Entry
K04138                      KO                                     

Name
ADRA2A
Definition
adrenergic receptor alpha-2A
Pathway
ko04022  cGMP-PKG signaling pathway
ko04080  Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP - PKG signaling pathway
    K04138  ADRA2A; adrenergic receptor alpha-2A
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04138  ADRA2A; adrenergic receptor alpha-2A
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04138  ADRA2A; adrenergic receptor alpha-2A
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04138  ADRA2A; adrenergic receptor alpha-2A
BRITE hierarchy
Other DBs
GO: 0004938
Genes
HSA: 150(ADRA2A)
PTR: 466201(ADRA2A)
PPS: 100977068(ADRA2A)
GGO: 101137632(ADRA2A)
PON: 100459426(ADRA2A)
NLE: 100586093(ADRA2A)
MCC: 695684(ADRA2A)
MCF: 102140075(ADRA2A)
CSAB: 103216513(ADRA2A)
RRO: 104667775(ADRA2A)
RBB: 108538806(ADRA2A)
CJC: 103796811(ADRA2A)
SBQ: 101039216(ADRA2A)
MMU: 11551(Adra2a)
RNO: 25083(Adra2a)
CGE: 100768369(Adra2a)
NGI: 103744368(Adra2a)
HGL: 101723298(Adra2a)
CCAN: 109691509(Adra2a)
OCU: 100009424(ADRA2A)
TUP: 102480728(ADRA2A)
CFA: 486888(ADRA2A)
AML: 100474011(ADRA2A)
UMR: 103659210(ADRA2A)
ORO: 101375317(ADRA2A)
FCA: 111559103 664736(ADRA2A)
PTG: 102948732(ADRA2A)
AJU: 106984750(ADRA2A)
BTA: 282135(ADRA2A)
BOM: 106700799(ADRA2A)
BIU: 109553206(ADRA2A)
PHD: 102341851(ADRA2A)
CHX: 102187024(ADRA2A)
OAS: 100170317(ADRA2A)
SSC: 399501(ADRA2A)
CFR: 102504908(ADRA2A)
CDK: 105091698(ADRA2A)
BACU: 103002174(ADRA2A)
LVE: 103085955(ADRA2A)
OOR: 101270435(ADRA2A)
ECB: 100147119(ADRA2A)
EPZ: 103564806(ADRA2A)
EAI: 106837560(ADRA2A)
MYB: 102259526(ADRA2A)
MYD: 102773898(ADRA2A)
HAI: 109384879(ADRA2A)
RSS: 109444046(ADRA2A)
PALE: 102881586(ADRA2A)
LAV: 100672320(ADRA2A)
TMU: 101343943
MDO: 100027878(ADRA2A)
SHR: 100929353(ADRA2A)
GGA: 428980(ADRA2A)
MGP: 104912010(ADRA2A)
CJO: 107316160(ADRA2A)
APLA: 101799674(ADRA2B) 101803955(ADRA2A)
ACYG: 106031884(ADRA2A)
TGU: 100231407(ADRA2A)
GFR: 102031657 102033754(ADRA2A)
FAB: 101809602(ADRA2A)
PHI: 102109587(ADRA2A)
PMAJ: 107206514(ADRA2A)
CCW: 104695286(ADRA2A)
FPG: 101913158(ADRA2A)
FCH: 102053594(ADRA2A)
CLV: 102090898(ADRA2A)
EGZ: 104130416(ADRA2A)
AAM: 106488367(ADRA2A)
ASN: 102376693(ADRA2A)
AMJ: 102576082(ADRA2A)
PSS: 102463694(ADRA2A)
CMY: 102938232(ADRA2A)
CPIC: 101932100(ADRA2A)
ACS: 100555911 100558331(adra2a)
PVT: 110071962(ADRA2A)
GJA: 107106572(ADRA2A) 107111528
XTR: 100493940 780304(adra2a)
NPR: 108791938(ADRA2A)
DRE: 266750(adra2a)
IPU: 108259429(adra2a)
AMEX: 103035996(adra2a)
TRU: 101064972(a2a1ar)
LCO: 104922185(adra2a) 104929743
NCC: 104956646(adra2a) 104958200
MZE: 101474890(adra2a) 101483007
OLA: 101164871(adra2a) 101170540
PRET: 103466293(adra2a) 103476774
NFU: 107390778(adra2a) 107395486
CSEM: 103384070(adra2a) 103387643
HCQ: 109510183 109519865(adra2a)
BPEC: 110156978 110166217(adra2a)
ELS: 105012128(adra2a)
SFM: 108918846(adra2a) 108936765
LCM: 102348663(ADRA2A)
CMK: 103185246(adra2a)
MYI: 110446675
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1353249
  Authors
Link R, Daunt D, Barsh G, Chruscinski A, Kobilka B
  Title
Cloning of two mouse genes encoding alpha 2-adrenergic receptor subtypes and identification of a single amino acid in the mouse alpha 2-C10 homolog responsible for an interspecies variation in antagonist binding.
  Journal
Mol Pharmacol 42:16-27 (1992)
  Sequence
[mmu:11551]

KEGG   ORTHOLOGY: K04139Help
Entry
K04139                      KO                                     

Name
ADRA2B
Definition
adrenergic receptor alpha-2B
Pathway
ko04022  cGMP-PKG signaling pathway
ko04080  Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP - PKG signaling pathway
    K04139  ADRA2B; adrenergic receptor alpha-2B
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04139  ADRA2B; adrenergic receptor alpha-2B
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04139  ADRA2B; adrenergic receptor alpha-2B
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04139  ADRA2B; adrenergic receptor alpha-2B
BRITE hierarchy
Other DBs
GO: 0004938
Genes
HSA: 151(ADRA2B)
PTR: 100614466(ADRA2B)
PPS: 100974246(ADRA2B)
GGO: 101150045(ADRA2B)
PON: 100441129(ADRA2B)
NLE: 100599451(ADRA2B)
MCC: 694825(ADRA2B)
MCF: 102116265(ADRA2B)
CSAB: 103241060(ADRA2B)
RRO: 104661450(ADRA2B)
RBB: 108520938(ADRA2B)
CJC: 100412057(ADRA2B)
SBQ: 101054037(ADRA2B)
MMU: 11552(Adra2b)
RNO: 24174(Adra2b)
CGE: 100757384(Adra2b)
NGI: 103738289(Adra2b)
HGL: 101701692(Adra2b)
CCAN: 109699320(Adra2b)
OCU: 100352237(ADRA2B)
TUP: 102497260(ADRA2B)
CFA: 100855976(ADRA2B)
AML: 100478006(ADRA2B)
UMR: 103671879(ADRA2B)
ORO: 101373812(ADRA2B)
FCA: 101090432(ADRA2B)
PTG: 102963560(ADRA2B)
AJU: 106976045(ADRA2B)
BTA: 516422(ADRA2B)
BOM: 102282250(ADRA2B)
BIU: 109565740(ADRA2B)
PHD: 102315592(ADRA2B)
CHX: 102175860(ADRA2B)
OAS: 100170318(ADRA2B)
SSC: 641353(ADRA2B)
CFR: 102507302(ADRA2B)
CDK: 105092851(ADRA2B)
BACU: 103021056(ADRA2B)
LVE: 103090019(ADRA2B)
OOR: 101270065(ADRA2B)
ECB: 100051684(ADRA2B)
EPZ: 103564055(ADRA2B)
EAI: 106845800(ADRA2B)
MYB: 102251180(ADRA2B)
MYD: 102761105(ADRA2B)
HAI: 109392022(ADRA2B)
RSS: 109444474(ADRA2B)
PALE: 102887994(ADRA2B)
LAV: 100662430(ADRA2B)
TMU: 101346183
MDO: 100033192(ADRA2B)
SHR: 100926877(ADRA2B)
OAA: 100084448(ADRA2B)
GGA: 101751513(ADRA2B) 426044(ELMOD3)
MGP: 104917109(ADRA2B)
CJO: 107323642(ADRA2B)
ACYG: 106048889(ADRA2B)
FPG: 101922013(ADRA2B)
AAM: 106493814(ADRA2B)
ASN: 102369411(ADRA2B)
AMJ: 102576495(ADRA2B)
PSS: 102455491(ADRA2B)
CMY: 102947396(ADRA2B)
CPIC: 101947916(ADRA2B)
ACS: 100561798
PVT: 110072120(ADRA2B)
PBI: 103057124(ADRA2B)
GJA: 107106751(ADRA2B)
XLA: 108711557(adra2b.L) 108712457(adra2b.S)
XTR: 100485811(adra2b)
NPR: 108797682(ADRA2B)
DRE: 100330650 266751(adra2b)
IPU: 108264887
AMEX: 103037863
MZE: 101484392
XMA: 102230342
PRET: 103470062
HCQ: 109526944
LCM: 102359002(ADRA2B) 102365269
CMK: 103187772(adra2b)
CIN: 100184338
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1336396
  Authors
Chen WM, Chang AC, Shie BJ, Chang YH, Chang NC
  Title
Molecular cloning and characterization of a mouse alpha 2C2 adrenoceptor subtype gene.
  Journal
Biochim Biophys Acta 1171:219-23 (1992)
DOI:10.1016/0167-4781(92)90126-K
  Sequence
[mmu:11552]

KEGG   ORTHOLOGY: K04140Help
Entry
K04140                      KO                                     

Name
ADRA2C
Definition
adrenergic receptor alpha-2C
Pathway
ko04022  cGMP-PKG signaling pathway
ko04080  Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP - PKG signaling pathway
    K04140  ADRA2C; adrenergic receptor alpha-2C
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04140  ADRA2C; adrenergic receptor alpha-2C
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04140  ADRA2C; adrenergic receptor alpha-2C
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04140  ADRA2C; adrenergic receptor alpha-2C
BRITE hierarchy
Other DBs
GO: 0004938
Genes
HSA: 152(ADRA2C)
PTR: 465178(ADRA2C)
PPS: 100993507(ADRA2C)
GGO: 101153693(ADRA2C)
PON: 100938399(ADRA2C)
NLE: 100591173(ADRA2C)
MCC: 719763(ADRA2C)
MCF: 102129584(ADRA2C)
CSAB: 103246439(ADRA2C)
RRO: 104653517
RBB: 108525445
MMU: 11553(Adra2c)
RNO: 24175(Adra2c)
CGE: 103161652(Adra2c)
NGI: 103741158(Adra2c)
HGL: 101723218(Adra2c)
CCAN: 109687429(Adra2c)
TUP: 102499472(ADRA2C)
CFA: 488793(ADRA2C)
AML: 100467814(ADRA2C)
ORO: 101373984(ADRA2C)
FCA: 101087990(ADRA2C)
PTG: 107179003
BTA: 407139(ADRA2C)
BOM: 102285813(ADRA2C)
CHX: 102181288(ADRA2C)
OAS: 100170319(ADRA2C)
SSC: 733706(ADRA2C)
CFR: 102520676(ADRA2C)
CDK: 105103347(ADRA2C)
BACU: 103008893(ADRA2C)
LVE: 103074700(ADRA2C)
OOR: 101288539(ADRA2C)
ECB: 111772982(ADRA2C)
EAI: 106840085
MYB: 102249134(ADRA2C)
MYD: 102767191(ADRA2C)
RSS: 109434491(ADRA2C)
PALE: 102895430(ADRA2C)
LAV: 100668918(ADRA2C)
TMU: 101359484
MDO: 100020740(ADRA2C)
SHR: 100927538(ADRA2C)
OAA: 100090717
GGA: 428799(ADRA2C)
MGP: 104909214(ADRA2C)
CJO: 107314070(ADRA2C)
APLA: 101790023(ADRA2C)
ACYG: 106033335(ADRA2C)
TGU: 101233463(ADRA2C)
GFR: 102039660(ADRA2C)
FAB: 101811765(ADRA2C)
PHI: 102111432(ADRA2C)
PMAJ: 107203559(ADRA2C)
CCW: 104690916(ADRA2C)
FPG: 101919690(ADRA2C)
FCH: 102053781(ADRA2C)
CLV: 102083610 102097195(ADRA2C)
EGZ: 104130208(ADRA2C)
AAM: 106498672(ADRA2C)
ASN: 102375154(ADRA2C)
AMJ: 102568542(ADRA2C)
PSS: 102447937(ADRA2C)
CMY: 102937639(ADRA2C)
CPIC: 101934570(ADRA2C) 101952800
PVT: 110069786
GJA: 107112872(ADRA2C)
XLA: 108697938(adra2c.L) 108705869(adra2c.S)
XTR: 100145449(adra2c)
NPR: 108785823(ADRA2C)
DRE: 266752(adra2c) 266754(adra2da) 266755(adra2db)
IPU: 108260662(adra2c) 108262932(adra2c) 108278623
LCM: 102353707 102355811(ADRA2C)
CMK: 103177286 103186334(adra2c)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2842764
  Authors
Regan JW, Kobilka TS, Yang-Feng TL, Caron MG, Lefkowitz RJ, Kobilka BK
  Title
Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype.
  Journal
Proc Natl Acad Sci U S A 85:6301-5 (1988)
DOI:10.1073/pnas.85.17.6301
  Sequence
[hsa:152]

KEGG   ORTHOLOGY: K04141Help
Entry
K04141                      KO                                     

Name
ADRB1
Definition
adrenergic receptor beta-1
Pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04024  cAMP signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04261  Adrenergic signaling in cardiomyocytes
ko04540  Gap junction
ko04923  Regulation of lipolysis in adipocytes
ko04924  Renin secretion
ko04970  Salivary secretion
ko05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K04141  ADRB1; adrenergic receptor beta-1
   04024 cAMP signaling pathway
    K04141  ADRB1; adrenergic receptor beta-1
   04022 cGMP - PKG signaling pathway
    K04141  ADRB1; adrenergic receptor beta-1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04141  ADRB1; adrenergic receptor beta-1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04141  ADRB1; adrenergic receptor beta-1
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocyte
    K04141  ADRB1; adrenergic receptor beta-1
   04924 Renin secretion
    K04141  ADRB1; adrenergic receptor beta-1
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04141  ADRB1; adrenergic receptor beta-1
  09154 Digestive system
   04970 Salivary secretion
    K04141  ADRB1; adrenergic receptor beta-1
 09160 Human Diseases
  09165 Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K04141  ADRB1; adrenergic receptor beta-1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04141  ADRB1; adrenergic receptor beta-1
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04141  ADRB1; adrenergic receptor beta-1
BRITE hierarchy
Other DBs
GO: 0004940
TC: 9.A.14.3.11
Genes
HSA: 153(ADRB1)
PTR: 466206(ADRB1)
PPS: 100978740(ADRB1)
GGO: 101149664(ADRB1)
PON: 100441708(ADRB1)
NLE: 100606030(ADRB1)
MCC: 100426598(ADRB1)
MCF: 107126443(ADRB1)
CSAB: 103216543(ADRB1)
RRO: 104659193(ADRB1)
RBB: 108542470(ADRB1)
CJC: 100387664(ADRB1)
MMU: 11554(Adrb1)
RNO: 24925(Adrb1)
CGE: 107978390
NGI: 103731758(Adrb1)
HGL: 101706546(Adrb1)
CCAN: 109678400(Adrb1)
OCU: 100338084(ADRB1)
TUP: 102478713(ADRB1)
CFA: 493972(ADRB1)
AML: 100471252(ADRB1)
ORO: 101365047(ADRB1)
FCA: 493971(ADRB1)
BTA: 281604(ADRB1)
BOM: 102270402(ADRB1)
BIU: 109553237(ADRB1)
PHD: 102326477(ADRB1)
CHX: 102187558(ADRB1)
OAS: 443528(ADRB1)
SSC: 397355(ADRB1)
CDK: 105104750(ADRB1)
BACU: 103003267(ADRB1)
LVE: 103082012(ADRB1)
OOR: 101286166(ADRB1)
ECB: 100146832(ADRB1)
MYB: 102258046(ADRB1)
HAI: 109392029(ADRB1)
RSS: 109444084(ADRB1)
PALE: 102880796(ADRB1)
LAV: 100654973(ADRB1)
TMU: 101347074
MDO: 100027410(ADRB1)
OAA: 100082919(ADRB1)
GGA: 101750705(ADRB1) 430991(ADRB3)
MGP: 100303680(ADRB1) 100379211(ADRB3)
CJO: 107316142(ADRB1) 107323791(ADRB3)
APLA: 101790405(ADRB1) 101801679(ADRB3)
ACYG: 106031933(ADRB1) 106044379(ADRB3)
TGU: 100221186 100221823(ADRB1)
GFR: 102034437(ADRB1)
FAB: 101805929(ADRB1) 101808175(ADRB3)
PHI: 102111297(ADRB3) 102113245(ADRB1)
PMAJ: 107207049(ADRB1) 107213844(ADRB3)
FPG: 101917348(ADRB1) 101918615(ADRB3)
FCH: 102052904(ADRB1) 106631091(ADRB3)
CLV: 102087468(ADRB1) 102099042(ADRB3)
EGZ: 104123630(ADRB1) 104127859(ADRB3)
ASN: 102368318(ADRB1)
AMJ: 102574660(ADRB1)
PSS: 102447221(ADRB1)
CMY: 102930847(ADRB1)
CPIC: 101935916(ADRB1) 101946563(ADRB3)
ACS: 100553597(adrb3) 100563228(adrb1)
PVT: 110071978(ADRB1) 110075175(ADRB3)
PBI: 103063417(ADRB3) 103066230(ADRB1)
GJA: 107108162(ADRB3) 107122433(ADRB1)
XLA: 108696008 108697308(X-Beta1AR) 108711602 108712710 399337(adrb1.L)
XTR: 100487086(adrb1)
NPR: 108799611 108802079(ADRB1)
DRE: 557194(adrb1) 558248(adrb3a) 792519(adrb3b)
IPU: 108265708 108273437(adrb1)
TRU: 101063257 101068216(adrb1)
LCO: 104927885(adrb1) 104930644(adrb3) 109136615
MZE: 101464662 101474916(adrb1)
OLA: 101156611(adrb1) 101174028
XMA: 102225838 102226151(adrb1)
PRET: 103470523 103481286(adrb1)
NFU: 107387883(adrb1) 107393740
CSEM: 103381516(adrb1) 103398145
LCF: 108878718 108898720(adrb1)
HCQ: 109511644 109523917(adrb1)
BPEC: 110154323(adrb1) 110169870
LCM: 102359969(ADRB1) 102361981(ADRB3)
CMK: 103186583(adrb1) 103190260(adrb3)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Pak Y, Pham N, Rotin D
  Title
Direct binding of the beta1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activation.
  Journal
Mol Cell Biol 22:7942-52 (2002)
DOI:10.1128/MCB.22.22.7942-7952.2002
  Sequence
[hsa:153]

KEGG   ORTHOLOGY: K04142Help
Entry
K04142                      KO                                     

Name
ADRB2
Definition
adrenergic receptor beta-2
Pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04024  cAMP signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04261  Adrenergic signaling in cardiomyocytes
ko04923  Regulation of lipolysis in adipocytes
ko04924  Renin secretion
ko04970  Salivary secretion
Disease
H00079  Asthma
H02106  Genetic obesity
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K04142  ADRB2; adrenergic receptor beta-2
   04024 cAMP signaling pathway
    K04142  ADRB2; adrenergic receptor beta-2
   04022 cGMP - PKG signaling pathway
    K04142  ADRB2; adrenergic receptor beta-2
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04142  ADRB2; adrenergic receptor beta-2
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocyte
    K04142  ADRB2; adrenergic receptor beta-2
   04924 Renin secretion
    K04142  ADRB2; adrenergic receptor beta-2
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04142  ADRB2; adrenergic receptor beta-2
  09154 Digestive system
   04970 Salivary secretion
    K04142  ADRB2; adrenergic receptor beta-2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04142  ADRB2; adrenergic receptor beta-2
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04142  ADRB2; adrenergic receptor beta-2
BRITE hierarchy
Other DBs
GO: 0004941
TC: 9.A.14.3.5
Genes
HSA: 154(ADRB2)
PTR: 471690(ADRB2)
PPS: 100983950(ADRB2)
GGO: 101142746(ADRB2)
PON: 100455509(ADRB2)
NLE: 100589389(ADRB2)
MCC: 710146(ADRB2)
MCF: 102144318(ADRB2)
CSAB: 103244769(ADRB2)
RRO: 104680760(ADRB2)
RBB: 108532068(ADRB2)
CJC: 100414106(ADRB2)
SBQ: 101034868(ADRB2)
MMU: 11555(Adrb2)
RNO: 24176(Adrb2)
CGE: 100758902(Adrb2)
HGL: 101708921(Adrb2)
CCAN: 109699099(Adrb2)
OCU: 100340821(ADRB2)
TUP: 102479303(ADRB2)
CFA: 403910(ADRB2)
AML: 100474451(ADRB2)
UMR: 103664828(ADRB2)
ORO: 101369132(ADRB2)
FCA: 493767(ADRB2)
PTG: 102963049(ADRB2)
AJU: 106981678(ADRB2)
BTA: 281605(ADRB2)
BOM: 102287887(ADRB2)
BIU: 109562177(ADRB2)
PHD: 102324704(ADRB2)
CHX: 102179381(ADRB2)
OAS: 100170320(ADRB2)
SSC: 397357(ADRB2)
CFR: 102514031(ADRB2)
CDK: 105097013(ADRB2)
BACU: 103006153(ADRB2)
LVE: 103071524(ADRB2)
OOR: 101276872(ADRB2)
ECB: 100060659(ADRB2)
EPZ: 103552981(ADRB2)
EAI: 106838476(ADRB2)
MYB: 102249639(ADRB2)
MYD: 102758663(ADRB2)
HAI: 109371751(ADRB2)
RSS: 109448762(ADRB2)
PALE: 102882861(ADRB2)
LAV: 100664615(ADRB2)
TMU: 101343539
MDO: 100031542(ADRB2)
SHR: 100928854(ADRB2)
GGA: 427623(ADRB2)
MGP: 100545804(ADRB2)
CJO: 107320450(ADRB2)
APLA: 101800857(ADRB2)
ACYG: 106042769(ADRB2)
TGU: 100221385(ADRB2)
GFR: 102034502(ADRB2)
FAB: 101808483(ADRB2)
PHI: 102102944(ADRB2)
PMAJ: 107210874(ADRB2)
CCW: 104689646(ADRB2)
FPG: 101919810(ADRB2)
FCH: 102054857(ADRB2)
CLV: 102087292(ADRB2)
EGZ: 104133630(ADRB2)
AAM: 106492678(ADRB3)
ASN: 102376687(ADRB2)
AMJ: 102567188(ADRB2)
PSS: 102456356(ADRB2)
CMY: 102947159(ADRB2)
CPIC: 101934241(ADRB2)
ACS: 100561097(adrb2)
PVT: 110086179
PBI: 103059387(ADRB2)
GJA: 107106463(ADRB2)
XLA: 398915(adrb2.S) 444218(adrb2.L)
XTR: 100144654(adrb2)
NPR: 108803519
DRE: 100037315(adrb2b) 565838(adrb2a)
IPU: 108278941
AMEX: 103035250 103041180(adrb2)
TRU: 101067397 101072937(adrb2)
NCC: 104944414
PRET: 103475673
HCQ: 109524471
SFM: 108934207 108936872(adrb2)
LCM: 102362748
CMK: 103188154(adrb2)
CIN: 100177102
APLC: 110987570
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Scarselli M, Donaldson JG
  Title
Constitutive internalization of G protein-coupled receptors and G proteins via clathrin-independent endocytosis.
  Journal
J Biol Chem 284:3577-85 (2009)
DOI:10.1074/jbc.M806819200
  Sequence
[hsa:154]

KEGG   ORTHOLOGY: K04143Help
Entry
K04143                      KO                                     

Name
ADRB3
Definition
adrenergic receptor beta-3
Pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04714  Thermogenesis
ko04923  Regulation of lipolysis in adipocytes
ko04924  Renin secretion
ko04970  Salivary secretion
Disease
H02106  Genetic obesity
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K04143  ADRB3; adrenergic receptor beta-3
   04022 cGMP - PKG signaling pathway
    K04143  ADRB3; adrenergic receptor beta-3
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04143  ADRB3; adrenergic receptor beta-3
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocyte
    K04143  ADRB3; adrenergic receptor beta-3
   04924 Renin secretion
    K04143  ADRB3; adrenergic receptor beta-3
  09154 Digestive system
   04970 Salivary secretion
    K04143  ADRB3; adrenergic receptor beta-3
  09159 Environmental adaptation
   04714 Thermogenesis
    K04143  ADRB3; adrenergic receptor beta-3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04143  ADRB3; adrenergic receptor beta-3
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Biogenic amine
   Adrenaline [OT]
    K04143  ADRB3; adrenergic receptor beta-3
BRITE hierarchy
Other DBs
GO: 0015052
Genes
HSA: 155(ADRB3)
PTR: 464113(ADRB3)
PPS: 100972927(ADRB3)
GGO: 101145102(ADRB3)
PON: 100454445(ADRB3)
NLE: 100596541(ADRB3)
MCC: 699129(ADRB3)
MCF: 102132220(ADRB3)
CSAB: 103215635(ADRB3)
RRO: 104679651(ADRB3)
RBB: 108513564(ADRB3)
CJC: 100396232(ADRB3)
SBQ: 101029188(ADRB3)
MMU: 11556(Adrb3)
RNO: 25645(Adrb3)
CGE: 100775030(Adrb3)
HGL: 101721160(Adrb3)
CCAN: 109675221(Adrb3)
OCU: 100339100(ADRB3)
CFA: 442979(ADRB3)
AML: 100469495(ADRB3)
ORO: 101386439(ADRB3)
FCA: 493930(ADRB3)
PTG: 102962125(ADRB3)
BTA: 281606(ADRB3)
BOM: 102279772(ADRB3)
BIU: 109553308(ADRB3)
PHD: 102321437(ADRB3)
CHX: 106503668(ADRB3)
OAS: 100294559(ADRB3)
SSC: 397356(ADRB3)
CFR: 102520443(ADRB3)
CDK: 105089947(ADRB3)
BACU: 103018060(ADRB3)
LVE: 103074465(ADRB3)
OOR: 101283051(ADRB3)
ECB: 100147322(ADRB3)
EPZ: 103567291(ADRB3)
EAI: 106837694(ADRB3)
MYB: 102249857(ADRB3)
MYD: 102764740(ADRB3)
HAI: 109393585(ADRB3)
RSS: 109456091(ADRB3)
PALE: 102879929(ADRB3)
LAV: 100674524(ADRB3)
TMU: 101347777
MDO: 100032947(ADRB3)
SHR: 100935351(ADRB3)
ASN: 102373388(ADRB3)
AMJ: 106737688(ADRB3)
CMY: 102930093
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Belge C, Hammond J, Dubois-Deruy E, Manoury B, Hamelet J, Beauloye C, Markl A, Pouleur AC, Bertrand L, Esfahani H, Jnaoui K, Gotz KR, Nikolaev VO, Vanderper A, Herijgers P, Lobysheva I, Iaccarino G, Hilfiker-Kleiner D, Tavernier G, Langin D, Dessy C, Balligand JL
  Title
Enhanced expression of beta3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.
  Journal
Circulation 129:451-62 (2014)
DOI:10.1161/CIRCULATIONAHA.113.004940
  Sequence
[hsa:155]

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