KEGG   ORTHOLOGY: K04199Help
Entry
K04199                      KO                                     

Name
MC1R
Definition
melanocortin 1 receptor
Pathway
ko04080  Neuroactive ligand-receptor interaction
ko04916  Melanogenesis
Disease
H00168  Oculocutaneous albinism (OCA)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04199  MC1R; melanocortin 1 receptor
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K04199  MC1R; melanocortin 1 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04199  MC1R; melanocortin 1 receptor
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Pituitary hormone
   Melanocortin
    K04199  MC1R; melanocortin 1 receptor
BRITE hierarchy
Genes
HSA: 4157(MC1R)
PTR: 493980(MC1R)
GGO: 101131674(MC1R)
MCC: 106995131(MC1R)
MCF: 102134454(MC1R)
RBB: 108512034(MC1R)
MMU: 17199(Mc1r)
RNO: 102552838(Mc1r)
NGI: 103741389(Mc1r)
HGL: 101726602(Mc1r)
CCAN: 109692762(Mc1r)
TUP: 102490338(MC1R)
CFA: 489652(MC1R)
AML: 105240967(MC1R)
UMR: 103673862(MC1R)
FCA: 493917(MC1R)
AJU: 106973524(MC1R)
BTA: 281298(MC1R)
BIU: 109572610(MC1R)
OAS: 102099064(MC1R)
SSC: 494018(MC1R)
CDK: 105104349(MC1R)
ECB: 100136907(MC1R)
EAI: 106828226(MC1R)
MYB: 106725236(MC1R)
MYD: 102765841(MC1R)
MDO: 100618641(MC1R)
SHR: 100921396(MC1R)
OAA: 103171385(MC1R)
GGA: 427562(MC1R)
MGP: 100542545(MC1R)
APLA: 101796989(MC1R)
ACYG: 106046609(MC1R)
TGU: 100225710(MC1R)
GFR: 102039427(MC1R)
PHI: 106628659(MC1R)
PMAJ: 107209606(MC1R)
FPG: 101913596(MC1R)
FCH: 102049270(MC1R)
CLV: 106145744(MC1R)
EGZ: 104130406(MC1R)
AAM: 106487428(MC1R)
ASN: 102380912(MC1R)
AMJ: 102560093(MC1R)
CMY: 102940360(MC1R)
CPIC: 101940692(MC1R)
XLA: 108715087
XTR: 100496792(mc1r)
NPR: 108795261(MC1R)
DRE: 353151(mc1r)
SRX: 107706122
SANH: 107662306
SGH: 107550117(mc1r)
CCAR: 109101368
TRU: 100187712(mc1r)
LCO: 104927426(mc1r)
NCC: 104964885(mc1r)
MZE: 101470947(mc1r)
OLA: 101171066(mc1r)
XMA: 102219655(mc1r)
PRET: 103462575(mc1r)
NFU: 107381320(mc1r)
CSEM: 103379178(mc1r)
LCF: 108877802(mc1r)
HCQ: 109531560(mc1r)
BPEC: 110175320(mc1r)
SASA: 106562271(mc1r)
ELS: 109616909(mc1r)
LCM: 102365500(MC1R)
EPA: 110254665
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Cooray SN, Clark AJ
  Title
Melanocortin receptors and their accessory proteins.
  Journal
Mol Cell Endocrinol 331:215-21 (2011)
DOI:10.1016/j.mce.2010.07.015

KEGG   ORTHOLOGY: K04200Help
Entry
K04200                      KO                                     

Name
MC2R
Definition
melanocortin 2 receptor
Pathway
ko04024  cAMP signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04925  Aldosterone synthesis and secretion
ko04927  Cortisol synthesis and secretion
ko04934  Cushing syndrome
Disease
H00033  Adrenal carcinoma
H00256  Familial glucocorticoid deficiency (FGD)
H01431  Cushing syndrome
H02049  Bilateral macronodular adrenal hyperplasia (BMAH)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    K04200  MC2R; melanocortin 2 receptor
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04200  MC2R; melanocortin 2 receptor
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    K04200  MC2R; melanocortin 2 receptor
   04927 Cortisol synthesis and secretion
    K04200  MC2R; melanocortin 2 receptor
 09160 Human Diseases
  09166 Endocrine and metabolic diseases
   04934 Cushing syndrome
    K04200  MC2R; melanocortin 2 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04200  MC2R; melanocortin 2 receptor
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Pituitary hormone
   Melanocortin
    K04200  MC2R; melanocortin 2 receptor
BRITE hierarchy
Genes
HSA: 4158(MC2R)
PTR: 455500(MC2R)
PPS: 100987960(MC2R)
GGO: 101143835(MC2R)
PON: 100436726(MC2R)
NLE: 100579327(MC2R)
MCC: 701312(MC2R)
MCF: 102138088(MC2R)
CSAB: 103222835(MC2R)
RRO: 104671837(MC2R)
RBB: 108533098(MC2R)
CJC: 108587692(MC2R)
SBQ: 101033240(MC2R)
MMU: 17200(Mc2r)
RNO: 282839(Mc2r)
CGE: 100757427(Mc2r)
NGI: 103727856(Mc2r)
HGL: 101699946(Mc2r)
CCAN: 109699704(Mc2r)
OCU: 100347821(MC2R)
TUP: 102491977(MC2R)
CFA: 100855756(MC2R)
AML: 100482443(MC2R)
UMR: 103680476(MC2R)
ORO: 101377845(MC2R)
FCA: 692350(MC2R)
PTG: 102953314(MC2R)
AJU: 106979644(MC2R)
BTA: 281299(MC2R)
BOM: 102279724(MC2R)
BIU: 109577760(MC2R)
PHD: 102341459(MC2R)
CHX: 102182364(MC2R)
OAS: 443482(MC2R)
SSC: 100739231(MC2R)
CFR: 102510856(MC2R)
CDK: 105086494(MC2R)
BACU: 103007152(MC2R)
LVE: 103083957(MC2R)
OOR: 101281347(MC2R)
ECB: 100057018(MC2R)
EPZ: 103555005(MC2R)
EAI: 106828648(MC2R)
MYB: 102244928(MC2R)
MYD: 102753039(MC2R)
HAI: 109378038(MC2R)
RSS: 109438691(MC2R)
PALE: 102898827(MC2R)
LAV: 100667193(MC2R)
TMU: 101345427
MDO: 100018891(MC2R)
SHR: 100915134(MC2R)
OAA: 100076508(MC2R)
GGA: 428516(MC2R)
MGP: 100543512(MC2R)
CJO: 107309913(MC2R)
APLA: 101799179(MC2R)
ACYG: 106034992(MC2R)
TGU: 100222030(MC2R) 100226074
GFR: 102043133(MC2R)
FAB: 101808205(MC2R)
PHI: 102112468(MC2R)
PMAJ: 107215252(MC2R)
CCW: 104687257(MC2R)
FPG: 101917528(MC2R)
FCH: 102047997(MC2R)
CLV: 102088391(MC2R)
EGZ: 104132876(MC2R)
AAM: 106482807(MC2R)
ASN: 102369299(MC2R)
AMJ: 102568636(MC2R)
PSS: 102457147(MC2R)
CMY: 102931474(MC2R)
CPIC: 101942963(MC2R)
ACS: 100558671(mc2r)
PVT: 110078045(MC2R)
PBI: 103053753(MC2R)
GJA: 107119709(MC2R)
XLA: 108718761(mc2r.L)
XTR: 100491330(mc2r)
NPR: 108798784(MC2R)
DRE: 353152(mc2r)
CCAR: 109110841
IPU: 108267950
AMEX: 103035428(mc2r)
LCO: 104932571(mc2r)
NCC: 104963813
MZE: 101487775
OLA: 101173003
XMA: 102230465
PRET: 103465894
NFU: 107378818
CSEM: 103388887(mc2r)
LCF: 108876285
HCQ: 109521865(mc2r)
BPEC: 110171420
SASA: 106592485
ELS: 105016486(mc2r)
SFM: 108940538(mc2r)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1325670
  Authors
Mountjoy KG, Robbins LS, Mortrud MT, Cone RD
  Title
The cloning of a family of genes that encode the melanocortin receptors.
  Journal
Science 257:1248-51 (1992)
  Sequence
[hsa:4158]
Reference
  Authors
Cooray SN, Clark AJ
  Title
Melanocortin receptors and their accessory proteins.
  Journal
Mol Cell Endocrinol 331:215-21 (2011)
DOI:10.1016/j.mce.2010.07.015

KEGG   ORTHOLOGY: K04201Help
Entry
K04201                      KO                                     

Name
MC3R
Definition
melanocortin 3 receptor
Pathway
ko04080  Neuroactive ligand-receptor interaction
Disease
H02106  Genetic obesity
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04201  MC3R; melanocortin 3 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04201  MC3R; melanocortin 3 receptor
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Pituitary hormone
   Melanocortin
    K04201  MC3R; melanocortin 3 receptor
BRITE hierarchy
Genes
HSA: 4159(MC3R)
PTR: 469978(MC3R)
PPS: 100973561(MC3R)
GGO: 101145697(MC3R)
PON: 100462452(MC3R)
NLE: 100606144(MC3R)
MCC: 698439(MC3R)
MCF: 102120087(MC3R)
CSAB: 103243927(MC3R)
RRO: 104656980(MC3R)
RBB: 108528504(MC3R)
CJC: 100400991(MC3R)
SBQ: 101030014(MC3R)
MMU: 17201(Mc3r)
RNO: 29310(Mc3r)
CGE: 100761648(Mc3r)
NGI: 103735751(Mc3r)
HGL: 101712663(Mc3r)
CCAN: 109690686(Mc3r)
OCU: 100346152(MC3R)
TUP: 102470643(MC3R)
CFA: 485938(MC3R)
AML: 100469853(MC3R)
UMR: 103670959(MC3R)
ORO: 101368230(MC3R)
FCA: 101091434(MC3R)
PTG: 102972379(MC3R)
AJU: 106970324(MC3R)
BTA: 505405(MC3R)
BOM: 102268012(MC3R)
BIU: 109567811(MC3R)
PHD: 102339943(MC3R)
CHX: 102171527(MC3R)
OAS: 101119579(MC3R)
SSC: 100141404(MC3R)
CFR: 102515438(MC3R)
CDK: 105098854(MC3R)
BACU: 103013382(MC3R)
LVE: 103079621(MC3R)
OOR: 101280699(MC3R)
ECB: 100054477(MC3R)
EPZ: 103561018(MC3R)
EAI: 106825893(MC3R)
MYB: 102241199(MC3R)
MYD: 102766363(MC3R)
HAI: 109380046(MC3R)
RSS: 109444602(MC3R)
PALE: 102879611(MC3R)
LAV: 100664876(MC3R)
TMU: 101352425
MDO: 100027970(MC3R)
SHR: 100915552(MC3R)
OAA: 100078727(MC3R)
GGA: 100857164(MC3R)
MGP: 100539222(MC3R)
CJO: 107323030(MC3R)
APLA: 101796011(MC3R)
ACYG: 106041853(MC3R)
TGU: 100225819(MC3R)
GFR: 102036709(MC3R)
FAB: 101814568(MC3R)
PHI: 102107424(MC3R)
PMAJ: 107213182(MC3R)
CCW: 104687606(MC3R)
FPG: 101924781(MC3R)
FCH: 102053545(MC3R)
CLV: 102098154(MC3R)
EGZ: 104132189(MC3R)
AAM: 106491743(MC3R)
ASN: 102378589(MC3R)
AMJ: 102561908(MC3R)
PSS: 102456972(MC3R)
CMY: 102931681(MC3R)
CPIC: 101939493(MC3R)
ACS: 100555674(mc3r)
PVT: 110081076(MC3R)
PBI: 103058916(MC3R)
GJA: 107112515(MC3R) 107125209
XLA: 108700911(mc3r.L) 108702609(mc3r.S)
XTR: 100496947(mc3r)
NPR: 108796308(MC3R)
DRE: 353153(mc3r)
SGH: 107581194
IPU: 108265186
AMEX: 103045867
ELS: 105022395
SFM: 108939132(mc3r)
LCM: 102347599(MC3R)
CMK: 103172895(mc3r)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Cooray SN, Clark AJ
  Title
Melanocortin receptors and their accessory proteins.
  Journal
Mol Cell Endocrinol 331:215-21 (2011)
DOI:10.1016/j.mce.2010.07.015

KEGG   ORTHOLOGY: K04202Help
Entry
K04202                      KO                                     

Name
MC4R
Definition
melanocortin 4 receptor
Pathway
ko04080  Neuroactive ligand-receptor interaction
Disease
H02106  Genetic obesity
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04202  MC4R; melanocortin 4 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04202  MC4R; melanocortin 4 receptor
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Pituitary hormone
   Melanocortin
    K04202  MC4R; melanocortin 4 receptor
BRITE hierarchy
Genes
HSA: 4160(MC4R)
PTR: 468556(MC4R)
PPS: 100980364(MC4R)
GGO: 101153120(MC4R)
PON: 100459483(MC4R)
NLE: 100594461(MC4R)
MCC: 698596(MC4R)
MCF: 102119180(MC4R)
CSAB: 103244186(MC4R)
RRO: 104662856(MC4R)
RBB: 108526391(MC4R)
CJC: 100405042(MC4R)
SBQ: 101044042(MC4R)
MMU: 17202(Mc4r)
RNO: 25635(Mc4r)
CGE: 100759720(Mc4r)
NGI: 103739614(Mc4r)
HGL: 101725964(Mc4r)
CCAN: 109677508(Mc4r)
OCU: 100355375(MC4R)
TUP: 102502724(MC4R)
CFA: 483961(MC4R)
AML: 100474731(MC4R)
UMR: 103675996(MC4R)
ORO: 101370198(MC4R)
FCA: 101081334(MC4R)
PTG: 102972736(MC4R)
AJU: 106986994(MC4R)
BTA: 281300(MC4R)
BOM: 102286686(MC4R)
BIU: 109577718(MC4R)
PHD: 102331690(MC4R)
CHX: 100861239(MC4R)
OAS: 100147707(MC4R)
SSC: 397359(MC4R)
CFR: 102515844(MC4R)
CDK: 105088991(MC4R)
BACU: 103012177(MC4R)
LVE: 103084384(MC4R)
OOR: 101274578(MC4R)
ECB: 100050469(MC4R)
EPZ: 103565805(MC4R)
EAI: 106842731(MC4R)
MYB: 102246399(MC4R)
MYD: 102758991(MC4R)
HAI: 109381727(MC4R)
RSS: 109446172(MC4R)
PALE: 102895001(MC4R)
LAV: 100677251(MC4R)
TMU: 101345462
MDO: 100016168(MC4R)
SHR: 100921147(MC4R)
OAA: 100073912(MC4R)
GGA: 428485(MC4R)
MGP: 100547162(MC4R)
CJO: 107309553(MC4R)
APLA: 101793277(MC4R)
ACYG: 106039909(MC4R)
TGU: 100218148(MC4R)
GFR: 102045519(MC4R)
PHI: 102114186(MC4R)
PMAJ: 107200903(MC4R)
CCW: 104689833(MC4R)
FPG: 101914418(MC4R)
FCH: 102055472(MC4R)
CLV: 102092308(MC4R)
EGZ: 104123467(MC4R)
ASN: 102368203(MC4R)
AMJ: 102565056(MC4R)
PSS: 102464037(MC4R)
CMY: 102933129
CPIC: 101940602(MC4R)
ACS: 100557051(mc4r)
PVT: 110075427(MC4R)
PBI: 103064645(MC4R)
GJA: 107123526(MC4R)
XLA: 108695258(mc4r.S) 108719094(mc4r.L)
XTR: 100486677(mc4r)
NPR: 108802086
DRE: 286833(mc4r)
IPU: 108280642
TRU: 445900(mc4r)
LCO: 104930272
NCC: 104961440
MZE: 101476237
OLA: 101174304
PRET: 103456700
NFU: 107383086
CSEM: 103377490
LCF: 108885079
HCQ: 109518715
BPEC: 110164121
SFM: 108927548
LCM: 102355468
CMK: 103179956(mc4r)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Cooray SN, Clark AJ
  Title
Melanocortin receptors and their accessory proteins.
  Journal
Mol Cell Endocrinol 331:215-21 (2011)
DOI:10.1016/j.mce.2010.07.015

KEGG   ORTHOLOGY: K04203Help
Entry
K04203                      KO                                     

Name
MC5R
Definition
melanocortin 5 receptor
Pathway
ko04080  Neuroactive ligand-receptor interaction
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04203  MC5R; melanocortin 5 receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04203  MC5R; melanocortin 5 receptor
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Pituitary hormone
   Melanocortin
    K04203  MC5R; melanocortin 5 receptor
BRITE hierarchy
Genes
HSA: 4161(MC5R)
PTR: 468599(MC5R)
PPS: 100988285(MC5R)
GGO: 101143231(MC5R)
PON: 100441938(MC5R)
NLE: 100607768(MC5R)
MCC: 701447(MC5R)
MCF: 102137325(MC5R)
CSAB: 103222834(MC5R)
RRO: 104671846(MC5R)
RBB: 108533081(MC5R)
CJC: 100406396(MC5R)
SBQ: 101032708(MC5R)
MMU: 17203(Mc5r)
RNO: 25726(Mc5r)
CGE: 100758289(Mc5r)
NGI: 103727872(Mc5r)
HGL: 101699585(Mc5r)
CCAN: 109699699(Mc5r)
OCU: 100348068(MC5R)
TUP: 102491561(MC5R)
CFA: 483981(MC5R)
AML: 100483197(MC5R)
UMR: 103680477(MC5R)
ORO: 101381001(MC5R)
FCA: 101093399(MC5R)
PTG: 102969766(MC5R)
AJU: 106979643(MC5R)
BTA: 507987(MC5R)
BOM: 102280004(MC5R)
BIU: 109577762(MC5R)
PHD: 102341821(MC5R)
CHX: 102181742(MC5R)
OAS: 780501(MC5R)
SSC: 100622278(MC5R)
CFR: 102510626(MC5R)
CDK: 105086495(MC5R)
ECB: 106780948(MC5R)
EPZ: 103555004(MC5R)
EAI: 106828647(MC5R)
MYB: 102244327(MC5R)
MYD: 102753496(MC5R)
HAI: 109396438(MC5R)
RSS: 109438692(MC5R)
PALE: 102877727(MC5R)
LAV: 100666906(MC5R)
MDO: 100018855(MC5R)
SHR: 100914880(MC5R)
OAA: 100089437(MC5R)
GGA: 421047(MC5R)
MGP: 100543664(MC5R)
CJO: 107309987(MC5R)
APLA: 101798376(MC5R)
ACYG: 106034991(MC5R)
TGU: 100226898(MC5R)
GFR: 102043409(MC5R)
FAB: 101818638(MC5R)
PHI: 102112158(MC5R)
PMAJ: 107214069(MC5R)
CCW: 104687258(MC5R)
FPG: 101915803(MC5R)
FCH: 102048278 102054082(MC5R)
CLV: 102088077(MC5R)
EGZ: 104132860(MC5R)
ASN: 102387347(MC5R)
AMJ: 102566327(MC5R)
PSS: 102454567(MC5R)
CMY: 102931027(MC5R)
CPIC: 101940141(MC5R)
ACS: 103278545(mc5r)
PVT: 110078029(MC5R)
PBI: 103053988(MC5R)
GJA: 107119717(MC5R)
XLA: 108695236(mc5r.S) 108719177(mc5r.L)
XTR: 100124993(mc5r)
NPR: 108787323(MC5R)
DRE: 286834(mc5ra) 286835(mc5rb)
TRU: 445999(mc5r)
LCO: 104932570(mc5r)
MZE: 101487483
OLA: 101174292
XMA: 102230201
PRET: 103465896
NFU: 107378820
CSEM: 103388888
LCF: 108876282
HCQ: 109521864
BPEC: 110171594
LCM: 102367047(MC5R)
APLC: 110981739
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Cooray SN, Clark AJ
  Title
Melanocortin receptors and their accessory proteins.
  Journal
Mol Cell Endocrinol 331:215-21 (2011)
DOI:10.1016/j.mce.2010.07.015

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