KEGG   ORTHOLOGY: K04200Help
Entry
K04200                      KO                                     

Name
MC2R
Definition
melanocortin 2 receptor
Pathway
ko04024  cAMP signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04925  Aldosterone synthesis and secretion
ko04927  Cortisol synthesis and secretion
ko04934  Cushing's syndrome
Disease
H00033  Adrenal carcinoma
H00256  Familial glucocorticoid deficiency (FGD)
H01431  Cushing's syndrome
H02049  Bilateral macronodular adrenal hyperplasia (BMAH)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04024 cAMP signaling pathway
    K04200  MC2R; melanocortin 2 receptor
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04200  MC2R; melanocortin 2 receptor
 Organismal Systems
  Endocrine system
   04925 Aldosterone synthesis and secretion
    K04200  MC2R; melanocortin 2 receptor
   04927 Cortisol synthesis and secretion
    K04200  MC2R; melanocortin 2 receptor
 Human Diseases
  Endocrine and metabolic diseases
   04934 Cushing's syndrome
    K04200  MC2R; melanocortin 2 receptor
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Pituitary hormone
   Melanocortin
    K04200  MC2R; melanocortin 2 receptor
BRITE hierarchy
Genes
HSA: 4158(MC2R)
PTR: 455500(MC2R)
PPS: 100987960(MC2R)
GGO: 101143835(MC2R)
PON: 100436726(MC2R)
NLE: 100579327(MC2R)
MCC: 701312(MC2R)
MCF: 102138088(MC2R)
CSAB: 103222835(MC2R)
RRO: 104671837(MC2R)
RBB: 108533098(MC2R)
CJC: 108587692(MC2R)
SBQ: 101033240(MC2R)
MMU: 17200(Mc2r)
RNO: 282839(Mc2r)
CGE: 100757427(Mc2r)
NGI: 103727856(Mc2r)
HGL: 101699946(Mc2r)
CCAN: 109699704(Mc2r)
OCU: 100347821(MC2R)
TUP: 102491977(MC2R)
CFA: 100855756(MC2R)
AML: 100482443(MC2R)
UMR: 103680476(MC2R)
ORO: 101377845(MC2R)
FCA: 692350(MC2R)
PTG: 102953314(MC2R)
AJU: 106979644(MC2R)
BTA: 281299(MC2R)
BOM: 102279724(MC2R)
BIU: 109577760(MC2R)
PHD: 102341459(MC2R)
CHX: 102182364(MC2R)
OAS: 443482(MC2R)
SSC: 100739231(MC2R)
CFR: 102510856(MC2R)
CDK: 105086494(MC2R)
BACU: 103007152(MC2R)
LVE: 103083957(MC2R)
OOR: 101281347(MC2R)
ECB: 100057018(MC2R)
EPZ: 103555005(MC2R)
EAI: 106828648(MC2R)
MYB: 102244928(MC2R)
MYD: 102753039(MC2R)
HAI: 109378038(MC2R)
RSS: 109438691(MC2R)
PALE: 102898827(MC2R)
LAV: 100667193(MC2R)
TMU: 101345427
MDO: 100018891(MC2R)
SHR: 100915134(MC2R)
OAA: 100076508(MC2R)
GGA: 428516(MC2R)
MGP: 100543512(MC2R)
CJO: 107309913(MC2R)
APLA: 101799179(MC2R)
ACYG: 106034992(MC2R)
TGU: 100222030(MC2R) 100226074
GFR: 102043133(MC2R)
FAB: 101808205(MC2R)
PHI: 102112468(MC2R)
PMAJ: 107215252(MC2R)
CCW: 104687257(MC2R)
FPG: 101917528(MC2R)
FCH: 102047997(MC2R)
CLV: 102088391(MC2R)
EGZ: 104132876(MC2R)
AAM: 106482807(MC2R)
ASN: 102369299(MC2R)
AMJ: 102568636(MC2R)
PSS: 102457147(MC2R)
CMY: 102931474(MC2R)
CPIC: 101942963(MC2R)
ACS: 100558671(mc2r)
PVT: 110078045(MC2R)
PBI: 103053753(MC2R)
GJA: 107119709(MC2R)
XLA: 108718761(mc2r.L)
XTR: 100491330(mc2r)
NPR: 108798784(MC2R)
DRE: 353152(mc2r)
CCAR: 109110841
IPU: 108267950
AMEX: 103035428(mc2r)
LCO: 104932571(mc2r)
NCC: 104963813
MZE: 101487775
OLA: 101173003
XMA: 102230465
PRET: 103465894
NFU: 107378818
CSEM: 103388887(mc2r)
LCF: 108876285
HCQ: 109521865(mc2r)
BPEC: 110171420
SASA: 106592485
ELS: 105016486(mc2r)
SFM: 108940538(mc2r)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1325670
  Authors
Mountjoy KG, Robbins LS, Mortrud MT, Cone RD
  Title
The cloning of a family of genes that encode the melanocortin receptors.
  Journal
Science 257:1248-51 (1992)
  Sequence
[hsa:4158]
Reference
  Authors
Cooray SN, Clark AJ
  Title
Melanocortin receptors and their accessory proteins.
  Journal
Mol Cell Endocrinol 331:215-21 (2011)
DOI:10.1016/j.mce.2010.07.015

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