KEGG   ORTHOLOGY: K04289Help
Entry
K04289                      KO                                     

Name
LPAR1, EDG2
Definition
lysophosphatidic acid receptor 1
Pathway
ko04015  Rap1 signaling pathway
ko04072  Phospholipase D signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04540  Gap junction
ko04810  Regulation of actin cytoskeleton
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
   04072 Phospholipase D signaling pathway
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
   04151 PI3K-Akt signaling pathway
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
 09160 Human Diseases
  09161 Cancers
   05200 Pathways in cancer
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Lipid
   Lysophosphatidic acid [OT]
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
BRITE hierarchy
Other DBs
GO: 0070915
Genes
HSA: 1902(LPAR1)
PTR: 464655(LPAR1)
PPS: 100981266(LPAR1)
GGO: 101144872(LPAR1)
PON: 100458931(LPAR1)
NLE: 100589911(LPAR1)
MCC: 709208(LPAR1)
MCF: 101864894(LPAR1) 102125640
CSAB: 103219021(LPAR1)
RRO: 104664137(LPAR1)
RBB: 108513979
CJC: 100414340(LPAR1)
SBQ: 101035023(LPAR1)
MMU: 14745(Lpar1)
RNO: 116744(Lpar1)
CGE: 100757522(Lpar1)
NGI: 103732526(Lpar1)
HGL: 101713333(Lpar1)
CCAN: 109692877(Lpar1)
OCU: 100355169(LPAR1)
TUP: 102503029(LPAR1)
CFA: 474800(LPAR1)
AML: 100479569(LPAR1)
UMR: 103678568(LPAR1)
ORO: 101371767(LPAR1)
FCA: 101092556(LPAR1)
PTG: 102968521(LPAR1)
AJU: 106971772(LPAR1)
BTA: 281136(LPAR1)
BOM: 102273019(LPAR1)
BIU: 109563336(LPAR1) 109563337
PHD: 102316257(LPAR1)
CHX: 102189399(LPAR1)
OAS: 443346(LPAR1)
SSC: 100512581(LPAR1)
CFR: 102522277(LPAR1)
CDK: 105096434(LPAR1)
BACU: 103015300(LPAR1)
LVE: 103091078(LPAR1)
OOR: 101274338(LPAR1)
ECB: 100053797(LPAR1)
EPZ: 103546686(LPAR1)
EAI: 106826903(LPAR1)
MYB: 102258769(LPAR1)
MYD: 102762844(LPAR1)
HAI: 109379349(LPAR1)
RSS: 109456987(LPAR1)
PALE: 102891503(LPAR1)
LAV: 100668056(LPAR1)
TMU: 101344103
MDO: 100016607(LPAR1)
SHR: 100928953(LPAR1)
OAA: 100077696(LPAR1)
GGA: 427339(LPAR1)
MGP: 100541536(LPAR1)
CJO: 107306591(LPAR1)
APLA: 101802482(LPAR1)
ACYG: 106043035(LPAR1)
TGU: 100223722(LPAR1)
GFR: 102038748(LPAR1)
FAB: 101814928 101819651(LPAR1)
PHI: 102111782(LPAR1)
PMAJ: 107198333(LPAR1)
CCW: 104690481(LPAR1)
FPG: 101920309(LPAR1)
FCH: 102058846(LPAR1)
CLV: 102084885(LPAR1)
EGZ: 104123052(LPAR1)
AAM: 106499585(LPAR1)
ASN: 102382491(LPAR1)
AMJ: 102563758(LPAR1)
PSS: 102445645(LPAR1)
CMY: 102935396(LPAR1)
CPIC: 101932155(LPAR1)
ACS: 100565601(lpar1)
PVT: 110077739(LPAR1)
PBI: 103053763(LPAR1)
GJA: 107108929 107114523(LPAR1)
XLA: 373591(lpar1.L) 379403(lpar1.S)
XTR: 100124893(lpar1)
NPR: 108787629(LPAR1)
DRE: 368461(lpar1)
SANH: 107653498(lpar1)
IPU: 108257275(lpar2) 108277333(lpar1)
TRU: 101075588(lpar1)
LCO: 104918571 104927704(lpar1)
NCC: 104964645(lpar1)
MZE: 101483503 101487294(lpar1)
OLA: 101164735(lpar1)
XMA: 102222146(lpar1)
PRET: 103473989(lpar1)
NFU: 107396668(lpar1)
CSEM: 103390307(lpar1) 103399363
LCF: 108880309(lpar1)
HCQ: 109530147(lpar1)
BPEC: 110166379
ELS: 105023381(lpar2) 105026669(lpar1)
SFM: 108936306
LCM: 102349282(LPAR1) 102356779
CMK: 103174454 103187154(lpar1)
CIN: 100182538
TCA: 103312315
TSP: Tsp_09408
ADF: 107357274
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Noguchi K, Herr D, Mutoh T, Chun J
  Title
Lysophosphatidic acid (LPA) and its receptors.
  Journal
Curr Opin Pharmacol 9:15-23 (2009)
DOI:10.1016/j.coph.2008.11.010
Reference
PMID:9070858
  Authors
An S, Dickens MA, Bleu T, Hallmark OG, Goetzl EJ
  Title
Molecular cloning of the human Edg2 protein and its identification as a functional cellular receptor for lysophosphatidic acid.
  Journal
Biochem Biophys Res Commun 231:619-22 (1997)
DOI:10.1006/bbrc.1997.6150
  Sequence
[hsa:1902]

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