KEGG   ORTHOLOGY: K04344Help
Entry
K04344                      KO                                     

Name
CACNA1A, CAV2.1
Definition
voltage-dependent calcium channel P/Q type alpha-1A
Pathway
ko04010  MAPK signaling pathway
ko04020  Calcium signaling pathway
ko04721  Synaptic vesicle cycle
ko04723  Retrograde endocannabinoid signaling
ko04724  Glutamatergic synapse
ko04725  Cholinergic synapse
ko04726  Serotonergic synapse
ko04727  GABAergic synapse
ko04728  Dopaminergic synapse
ko04730  Long-term depression
ko04742  Taste transduction
ko04930  Type II diabetes mellitus
ko05032  Morphine addiction
ko05033  Nicotine addiction
Disease
H00063  Spinocerebellar ataxia (SCA)
H00606  Early infantile epileptic encephalopathy
H00749  Episodic ataxias
H00775  Familial or sporadic hemiplegic migraine
H01808  Hemiconvulsion-hemiplegia-epilepsy syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
   04020 Calcium signaling pathway
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
   04727 GABAergic synapse
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
   04725 Cholinergic synapse
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
   04728 Dopaminergic synapse
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
   04726 Serotonergic synapse
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
   04730 Long-term depression
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
   04723 Retrograde endocannabinoid signaling
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
   04721 Synaptic vesicle cycle
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
  09157 Sensory system
   04742 Taste transduction
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
 09160 Human Diseases
  09164 Substance dependence
   05032 Morphine addiction
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
   05033 Nicotine addiction
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
  09166 Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   K04344  CACNA1A, CAV2.1; voltage-dependent calcium channel P/Q type alpha-1A
BRITE hierarchy
Other DBs
GO: 0005245
TC: 1.A.1.11.8 1.A.1.11.27
Genes
HSA: 773(CACNA1A)
PTR: 455766(CACNA1A)
PPS: 100971898(CACNA1A)
GGO: 101127257(CACNA1A)
PON: 100458387(CACNA1A)
NLE: 100602682(CACNA1A)
MCC: 718291(CACNA1A)
MCF: 102130052(CACNA1A)
CSAB: 103234371(CACNA1A)
RRO: 104661142(CACNA1A)
RBB: 108544091(CACNA1A)
CJC: 100390599(CACNA1A)
SBQ: 101046396(CACNA1A)
MMU: 12286(Cacna1a)
RNO: 25398(Cacna1a)
CGE: 100758171(Cacna1a)
NGI: 103751913(Cacna1a)
HGL: 101725815(Cacna1a)
CCAN: 109681262(Cacna1a)
OCU: 100009265(CACNA1A)
TUP: 102473903(CACNA1A)
CFA: 100686650(CACNA1A)
AML: 100473951(CACNA1A)
UMR: 103682191
ORO: 101378448(CACNA1A)
FCA: 101094827(CACNA1A)
PTG: 102962991(CACNA1A)
AJU: 106986103(CACNA1A)
BTA: 282648(CACNA1A)
BOM: 102266763(CACNA1A)
BIU: 109560900(CACNA1A)
PHD: 102336555(CACNA1A)
CHX: 102168441(CACNA1A)
OAS: 101120920(CACNA1A)
SSC: 100525387(CACNA1A)
CFR: 102516820(CACNA1A)
CDK: 105100784(CACNA1A)
BACU: 103007483(CACNA1A)
LVE: 103068318(CACNA1A)
OOR: 101275783(CACNA1A)
ECB: 100063873(CACNA1A)
EPZ: 103566268(CACNA1A)
EAI: 106844288(CACNA1A)
MYB: 102257882(CACNA1A)
MYD: 102771143(CACNA1A)
HAI: 109394251(CACNA1A)
RSS: 109454914(CACNA1A)
PALE: 102891789(CACNA1A)
LAV: 100655176(CACNA1A)
TMU: 101341628
MDO: 100021108(CACNA1A)
SHR: 100925240(CACNA1A)
OAA: 100078981(CACNA1A)
GGA: 107049790
PHI: 102099919(CACNA1A)
FPG: 101919186(CACNA1A)
FCH: 102053332
EGZ: 104125041
AAM: 106499950
ASN: 102376033(CACNA1A)
AMJ: 102564806(CACNA1A)
PSS: 102447240
CMY: 102933709(CACNA1A)
CPIC: 101943820(CACNA1A)
ACS: 100557580(cacna1a)
PVT: 110082653(CACNA1A)
PBI: 103050605(CACNA1A)
GJA: 107116856(CACNA1A)
XLA: 108710372 373828(cacna1a.S)
XTR: 100492135(cacna1a)
NPR: 108794965(CACNA1A)
DRE: 569528(cacna1ab)
TRU: 101072720(cacna1a)
MZE: 101484868(cacna1a)
XMA: 102225112 102236322(cacna1a)
PRET: 103462507(cacna1a) 103468620
NFU: 107376625 107391184(cacna1a)
CSEM: 103383187(cacna1a) 103392961
LCF: 108880719 108880807(cacna1a)
BPEC: 110156590(cacna1a) 110172680
ELS: 105012190(cacna1a) 105024166
SFM: 108927499(cacna1a) 108930696
LCM: 102354855(CACNA1A)
SHX: MS3_04963
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Rose SJ, Kriener LH, Heinzer AK, Fan X, Raike RS, van den Maagdenberg AM, Hess EJ
  Title
The first knockin mouse model of episodic ataxia type 2.
  Journal
Exp Neurol 261:553-62 (2014)
DOI:10.1016/j.expneurol.2014.08.001
  Sequence
[hsa:773]

KEGG   ORTHOLOGY: K04849Help
Entry
K04849                      KO                                     

Name
CACNA1B, CAV2.2
Definition
voltage-dependent calcium channel N type alpha-1B
Pathway
ko04010  MAPK signaling pathway
ko04020  Calcium signaling pathway
ko04721  Synaptic vesicle cycle
ko04723  Retrograde endocannabinoid signaling
ko04725  Cholinergic synapse
ko04726  Serotonergic synapse
ko04727  GABAergic synapse
ko04728  Dopaminergic synapse
ko04930  Type II diabetes mellitus
ko05032  Morphine addiction
ko05033  Nicotine addiction
Disease
H00831  Primary dystonia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
   04020 Calcium signaling pathway
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
 09150 Organismal Systems
  09156 Nervous system
   04727 GABAergic synapse
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
   04725 Cholinergic synapse
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
   04728 Dopaminergic synapse
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
   04726 Serotonergic synapse
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
   04723 Retrograde endocannabinoid signaling
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
   04721 Synaptic vesicle cycle
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
 09160 Human Diseases
  09164 Substance dependence
   05032 Morphine addiction
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
   05033 Nicotine addiction
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
  09166 Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
BRITE hierarchy
Other DBs
GO: 0005245
TC: 1.A.1.11.9
Genes
HSA: 774(CACNA1B)
PTR: 464893(CACNA1B)
PPS: 100979369(CACNA1B)
GGO: 101123776(CACNA1B)
PON: 100450868(CACNA1B)
NLE: 100584807(CACNA1B)
MCC: 721452(CACNA1B)
MCF: 101925455
CSAB: 103239541(CACNA1B)
RRO: 104669605(CACNA1B)
RBB: 108542921(CACNA1B)
CJC: 100390442(CACNA1B)
SBQ: 101049976(CACNA1B)
MMU: 12287(Cacna1b)
RNO: 257648(Cacna1b)
NGI: 103732608(Cacna1b)
HGL: 101697609(Cacna1b)
OCU: 100008979(CACNA1B)
TUP: 102498317(CACNA1B)
CFA: 480660(CACNA1B)
AML: 100466608(CACNA1B)
UMR: 103675324(CACNA1B)
FCA: 101087362(CACNA1B)
PTG: 102954775(CACNA1B)
BTA: 282410(CACNA1B)
BOM: 102266839(CACNA1B)
BIU: 109565692(CACNA1B)
PHD: 102330644(CACNA1B)
CHX: 102189138(CACNA1B)
OAS: 101122774
SSC: 102164336(CACNA1B)
CFR: 102521766(CACNA1B)
CDK: 105102103(CACNA1B)
BACU: 103004988(CACNA1B)
LVE: 103073411(CACNA1B)
OOR: 101272416(CACNA1B)
ECB: 100058760(CACNA1B)
EPZ: 103554173(CACNA1B)
EAI: 106822757(CACNA1B)
MYB: 102245786(CACNA1B)
MYD: 102756826(CACNA1B)
HAI: 109382541(CACNA1B)
RSS: 109437268(CACNA1B)
PALE: 102877847(CACNA1B)
LAV: 100660444(CACNA1B)
TMU: 101351661
MDO: 100023896(CACNA1B)
SHR: 100933192(CACNA1B)
OAA: 100681261(CACNA1B)
GGA: 374169(CACNA1B)
MGP: 100539318(CACNA1B)
CJO: 107321666(CACNA1B)
APLA: 101794161(CACNA1B)
ACYG: 106037093(CACNA1B)
TGU: 100230125(CACNA1B)
GFR: 102043304(CACNA1B)
FAB: 101812454(CACNA1B)
PHI: 102107124(CACNA1B)
PMAJ: 107211935(CACNA1B)
CCW: 104688232(CACNA1B)
FPG: 101922058(CACNA1B)
FCH: 102058219(CACNA1B)
CLV: 102086328(CACNA1B)
EGZ: 104124015(CACNA1B)
AAM: 106497478(CACNA1B)
ASN: 102374664(CACNA1B)
AMJ: 102564626(CACNA1B)
PSS: 102452356(CACNA1B)
CMY: 102935334(CACNA1B)
CPIC: 101941901(CACNA1B)
ACS: 100565533(cacna1b)
PVT: 110089800(CACNA1B)
PBI: 103051885
GJA: 107118784(CACNA1B)
XLA: 100462926(cacna1b.S) 108699890
XTR: 100489231
NPR: 108794388(CACNA1B)
DRE: 555941(cacna1ba) 562796(cacna1bb)
TRU: 101072690(cacna1b)
LCF: 108878412(cacna1b) 108889014
HCQ: 109527074
LCM: 102345610(CACNA1B)
CMK: 103180424(cacna1b)
CIN: 100184382
TSP: Tsp_10911
MYI: 110467402
OBI: 106879088
LAK: 106170041
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Keum D, Baek C, Kim DI, Kweon HJ, Suh BC
  Title
Voltage-dependent regulation of CaV2.2 channels by Gq-coupled receptor is facilitated by membrane-localized beta subunit.
  Journal
J Gen Physiol 144:297-309 (2014)
DOI:10.1085/jgp.201411245
  Sequence
[hsa:774]

KEGG   ORTHOLOGY: K04852Help
Entry
K04852                      KO                                     

Name
CACNA1E, CAV2.3
Definition
voltage-dependent calcium channel R type alpha-1E
Pathway
ko04010  MAPK signaling pathway
ko04020  Calcium signaling pathway
ko04930  Type II diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04852  CACNA1E, CAV2.3; voltage-dependent calcium channel R type alpha-1E
   04020 Calcium signaling pathway
    K04852  CACNA1E, CAV2.3; voltage-dependent calcium channel R type alpha-1E
 09160 Human Diseases
  09166 Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04852  CACNA1E, CAV2.3; voltage-dependent calcium channel R type alpha-1E
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04852  CACNA1E, CAV2.3; voltage-dependent calcium channel R type alpha-1E
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   K04852  CACNA1E, CAV2.3; voltage-dependent calcium channel R type alpha-1E
BRITE hierarchy
Other DBs
GO: 0005245
TC: 1.A.1.11.3
Genes
HSA: 777(CACNA1E)
PTR: 457564(CACNA1E)
PPS: 100973580(CACNA1E)
GGO: 101152448(CACNA1E)
PON: 100456069(CACNA1E)
NLE: 100607010(CACNA1E)
MCC: 718092(CACNA1E)
MCF: 102137898(CACNA1E)
CSAB: 103230478(CACNA1E)
RRO: 104666781(CACNA1E)
RBB: 108512687
CJC: 100406548(CACNA1E)
SBQ: 101040860(CACNA1E)
MMU: 12290(Cacna1e)
RNO: 54234(Cacna1e)
CGE: 100773594(Cacna1e)
NGI: 103731375(Cacna1e)
HGL: 101701145(Cacna1e)
CCAN: 109680409(Cacna1e)
OCU: 100009403(CACNA1E)
TUP: 102488737(CACNA1E)
CFA: 490305(CACNA1E)
AML: 100466242(CACNA1E)
UMR: 103672437(CACNA1E)
ORO: 101364776(CACNA1E)
FCA: 101093985(CACNA1E)
PTG: 102961472(CACNA1E) 107180959
AJU: 106966786(CACNA1E)
BTA: 353113(CACNA1E)
BOM: 102271361(CACNA1E)
BIU: 109570739(CACNA1E)
PHD: 102323438(CACNA1E)
CHX: 102184834(CACNA1E)
OAS: 101102503(CACNA1E)
SSC: 100511769(CACNA1E)
CFR: 102509504(CACNA1E)
CDK: 105096253(CACNA1E)
BACU: 103008378(CACNA1E)
LVE: 103070069(CACNA1E)
OOR: 101287634(CACNA1E)
ECB: 100054582(CACNA1E)
EPZ: 103552092(CACNA1E)
EAI: 106833978(CACNA1E)
MYB: 102258772(CACNA1E)
MYD: 102766294(CACNA1E)
HAI: 109371489(CACNA1E)
RSS: 109448740(CACNA1E)
PALE: 102894818(CACNA1E)
LAV: 100663606(CACNA1E)
TMU: 101356789
MDO: 100017762(CACNA1E)
SHR: 100915867(CACNA1E)
OAA: 100081909(CACNA1E)
GGA: 424412(CACNA1E)
MGP: 100547277(CACNA1E)
CJO: 107317272(CACNA1E)
APLA: 101795250(CACNA1E)
ACYG: 106047781(CACNA1E)
TGU: 100221799(CACNA1E)
GFR: 102043868(CACNA1E)
FAB: 101806626(CACNA1E)
PHI: 102110220(CACNA1E)
PMAJ: 107208269(CACNA1E)
CCW: 104693572
FPG: 101921612(CACNA1E)
FCH: 102050734(CACNA1E)
CLV: 102097507(CACNA1E)
EGZ: 104132092(CACNA1E)
AAM: 106493947 106493955(CACNA1E)
ASN: 102369133(CACNA1E)
AMJ: 102561875(CACNA1E)
PSS: 102444760(CACNA1E)
CMY: 102946100(CACNA1E)
CPIC: 101940446(CACNA1E)
ACS: 100567913(cacna1e)
PVT: 110077061(CACNA1E)
PBI: 103051634(CACNA1E)
XLA: 100462927(cacna1e.L) 108715639
XTR: 100488514(cacna1e)
NPR: 108792573(CACNA1E)
DRE: 564274(cacna1e)
TRU: 101077288
MZE: 101487658(cacna1e)
XMA: 102229093(cacna1e)
ELS: 105020186 105029164(cacna1e)
SFM: 108919055(cacna1e) 108935228
LCM: 102362201(CACNA1E)
CMK: 103184804(cacna1e)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kamp MA, Krieger A, Henry M, Hescheler J, Weiergraber M, Schneider T
  Title
Presynaptic 'Ca2.3-containing' E-type Ca channels share dual roles during neurotransmitter release.
  Journal
Eur J Neurosci 21:1617-25 (2005)
DOI:10.1111/j.1460-9568.2005.03984.x
  Sequence
[hsa:777]

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