KEGG   ORTHOLOGY: K04353Help
Entry
K04353                      KO                                     

Name
RAP1A
Definition
Ras-related protein Rap-1A
Pathway
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04024  cAMP signaling pathway
ko04062  Chemokine signaling pathway
ko04510  Focal adhesion
ko04530  Tight junction
ko04611  Platelet activation
ko04670  Leukocyte transendothelial migration
ko04720  Long-term potentiation
ko04722  Neurotrophin signaling pathway
ko04934  Cushing's syndrome
ko04972  Pancreatic secretion
ko05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
   04015 Rap1 signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
   04010 MAPK signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
   04024 cAMP signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K04353  RAP1A; Ras-related protein Rap-1A
   04530 Tight junction
    K04353  RAP1A; Ras-related protein Rap-1A
 Organismal Systems
  Immune system
   04611 Platelet activation
    K04353  RAP1A; Ras-related protein Rap-1A
   04670 Leukocyte transendothelial migration
    K04353  RAP1A; Ras-related protein Rap-1A
   04062 Chemokine signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
  Digestive system
   04972 Pancreatic secretion
    K04353  RAP1A; Ras-related protein Rap-1A
  Nervous system
   04720 Long-term potentiation
    K04353  RAP1A; Ras-related protein Rap-1A
   04722 Neurotrophin signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
 Human Diseases
  Cancers
   05211 Renal cell carcinoma
    K04353  RAP1A; Ras-related protein Rap-1A
  Endocrine and metabolic diseases
   04934 Cushing's syndrome
    K04353  RAP1A; Ras-related protein Rap-1A
GTP-binding proteins [BR:ko04031]
 Small (Monomeric) G-proteins
  Ras Family
   Rap [OT]
    K04353  RAP1A; Ras-related protein Rap-1A
BRITE hierarchy
Genes
HSA: 5906(RAP1A)
PTR: 469408(RAP1A)
PPS: 100980934(RAP1A)
GGO: 101125618(RAP1A)
PON: 100433839(RAP1A)
NLE: 100603891(RAP1A)
MCC: 704404(RAP1A)
MCF: 102144586(RAP1A)
CSAB: 103224221(RAP1A)
RRO: 104658932(RAP1A)
RBB: 108525739 108528085(RAP1A)
CJC: 100393183(RAP1A)
SBQ: 101048450(RAP1A)
MMU: 109905(Rap1a)
RNO: 295347(Rap1a)
CGE: 100751497(Rap1a)
NGI: 103734905(Rap1a)
HGL: 101698757(Rap1a)
CCAN: 109695156(Rap1a)
OCU: 100351588(RAP1A)
TUP: 102475072(RAP1A)
CFA: 483225(RAP1A)
AML: 100471801(RAP1A)
UMR: 103675043(RAP1A)
ORO: 101375466(RAP1A)
FCA: 101094942(RAP1A)
PTG: 102963243(RAP1A)
AJU: 106969628(RAP1A)
BTA: 282031(RAP1A)
BOM: 102286224(RAP1A)
BIU: 109555931(RAP1A)
PHD: 102344648(RAP1A)
CHX: 102176930(RAP1A)
OAS: 101115080(RAP1A)
SSC: 100153199(RAP1A)
CFR: 102516450(RAP1A)
CDK: 105102039(RAP1A)
BACU: 103017880(RAP1A)
LVE: 103069239(RAP1A)
OOR: 101287340(RAP1A)
ECB: 100049912 100058930(RAP1A)
EPZ: 103547802(RAP1A)
EAI: 106828599(RAP1A)
MYB: 102258771(RAP1A)
MYD: 102774675(RAP1A)
HAI: 109373546(RAP1A)
RSS: 109446732(RAP1A)
PALE: 102879271(RAP1A)
LAV: 100676220(RAP1A)
TMU: 101352801
MDO: 100033128(RAP1A)
SHR: 100935403(RAP1A)
GGA: 419867(RAP1A)
MGP: 100151696(RAP1A)
CJO: 107324916(RAP1A)
APLA: 101800296(RAP1A)
ACYG: 106041314(RAP1A)
TGU: 100151697(RAP1A)
GFR: 102036447(RAP1A)
FAB: 101806584(RAP1A)
PHI: 102112636(RAP1A)
PMAJ: 107214847(RAP1A)
CCW: 104692321(RAP1A)
FPG: 101924077(RAP1A)
FCH: 102052801(RAP1A)
CLV: 102089030(RAP1A)
EGZ: 104126794(RAP1A)
AAM: 106485263(RAP1A)
ASN: 102385556(RAP1A)
AMJ: 102571106(RAP1A)
PSS: 102461781(RAP1A)
CMY: 102948045(RAP1A)
CPIC: 101952443(RAP1A)
ACS: 100556443(rap1a)
PVT: 110072354(RAP1A)
PBI: 103065471(RAP1A)
GJA: 107112269(RAP1A)
XLA: 414290(rap1a) 779127(rap1a.L) 780738
XTR: 100124947(rap1a)
NPR: 108789680(RAP1A)
DRE: 406714(rap1ab) 415242(rap1aa)
IPU: 108255244(rap1b) 108265690(rap1a)
AMEX: 103022868 103047011(rap1a)
TRU: 101064935(rap1a) 101074250
OLA: 101167529
PRET: 103467749
CSEM: 103385603 103386699(rap1a)
SASA: 106566052(RAP1A) 106567206(RAP1B) 106572472(RAP1B) 106582744(RAP1B)
ELS: 105023688(rap1a)
SFM: 108928254(rap1a) 108930477
LCM: 102354992(RAP1A)
CMK: 103182425(rap1a)
CIN: 445785(rap1b)
SPU: 580151
APLC: 110982135
DME: Dmel_CG1956(Rap1)
DSI: Dsimw501_GD13432(Dsim_R)
MDE: 101892158
AAG: 5571900
AME: 413246(R)
BIM: 100747441
BTER: 100642405
SOC: 105197651
AEC: 105152361
ACEP: 105626421
PBAR: 105431454
HST: 105187881
CFO: 105257324
LHU: 105667796
PGC: 109860604
NVI: 100117170
TCA: 658243
DPA: 109533808
NVL: 108560620
BMOR: 692519(Ras3)
PMAC: 106712843
PRAP: 111000490
PXY: 105387719
API: 100166893
DNX: 107165088
ZNE: 110835691
TUT: 107362689
CEL: CELE_C27B7.8(rap-1)
CBR: CBG21720(Cbr-rap-1)
BMY: Bm1_39445
TSP: Tsp_14059
OBI: 106872353
SHX: MS3_03938
EPA: 110236776
DDI: DDB_G0272857(rapB)
DPP: DICPUDRAFT_26434(rapB)
DFA: DFA_02753
EHI: EHI_004860(203.t00010) EHI_058090(179.t00009) EHI_101260(5.t00090)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2642744
  Authors
Kitayama H, Sugimoto Y, Matsuzaki T, Ikawa Y, Noda M
  Title
A ras-related gene with transformation suppressor activity.
  Journal
Cell 56:77-84 (1989)
DOI:10.1016/0092-8674(89)90985-9
  Sequence
[hsa:5906]

KEGG   ORTHOLOGY: K07836Help
Entry
K07836                      KO                                     

Name
RAP1B
Definition
Ras-related protein Rap-1B
Pathway
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04024  cAMP signaling pathway
ko04062  Chemokine signaling pathway
ko04510  Focal adhesion
ko04611  Platelet activation
ko04670  Leukocyte transendothelial migration
ko04720  Long-term potentiation
ko04722  Neurotrophin signaling pathway
ko04934  Cushing's syndrome
ko04972  Pancreatic secretion
ko05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
   04015 Rap1 signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
   04010 MAPK signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
   04024 cAMP signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K07836  RAP1B; Ras-related protein Rap-1B
 Organismal Systems
  Immune system
   04611 Platelet activation
    K07836  RAP1B; Ras-related protein Rap-1B
   04670 Leukocyte transendothelial migration
    K07836  RAP1B; Ras-related protein Rap-1B
   04062 Chemokine signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
  Digestive system
   04972 Pancreatic secretion
    K07836  RAP1B; Ras-related protein Rap-1B
  Nervous system
   04720 Long-term potentiation
    K07836  RAP1B; Ras-related protein Rap-1B
   04722 Neurotrophin signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
 Human Diseases
  Cancers
   05211 Renal cell carcinoma
    K07836  RAP1B; Ras-related protein Rap-1B
  Endocrine and metabolic diseases
   04934 Cushing's syndrome
    K07836  RAP1B; Ras-related protein Rap-1B
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K07836  RAP1B; Ras-related protein Rap-1B
  Exosomal proteins of other body fluids (saliva and urine)
   K07836  RAP1B; Ras-related protein Rap-1B
  Exosomal proteins of colorectal cancer cells
   K07836  RAP1B; Ras-related protein Rap-1B
GTP-binding proteins [BR:ko04031]
 Small (Monomeric) G-proteins
  Ras Family
   Rap [OT]
    K07836  RAP1B; Ras-related protein Rap-1B
BRITE hierarchy
Genes
HSA: 5908(RAP1B)
PTR: 452065(RAP1B)
PPS: 100995578(RAP1B)
GGO: 101125880(RAP1B)
PON: 100171907(RAP1B)
NLE: 100593411(RAP1B)
MCC: 693750 718171(RAP1B)
MCF: 102133022(RAP1B)
CSAB: 103215555 103238680(RAP1B)
RRO: 104658672(RAP1B)
RBB: 108532250(RAP1B)
CJC: 100411763 100413220(RAP1B)
SBQ: 101036065(RAP1B)
MMU: 215449(Rap1b)
RNO: 171337(Rap1b)
CGE: 100769542(Rap1b)
NGI: 103745076(Rap1b)
HGL: 101714409 101726671(Rap1b)
CCAN: 109699305
OCU: 100339891(RAP1B)
TUP: 102472381(RAP1B)
CFA: 608981(RAP1B)
AML: 100480240(RAP1B)
UMR: 103656863(RAP1B) 103659828
ORO: 101383971(RAP1B)
FCA: 101095993(RAP1B)
PTG: 102965011(RAP1B)
AJU: 106966345(RAP1B)
BTA: 327708(RAP1B) 789148
BIU: 109559248(RAP1B)
PHD: 102341520(RAP1B)
CHX: 102174543(RAP1B)
OAS: 101106317(RAP1B)
SSC: 100152555(RAP1B)
CFR: 102524037(RAP1B)
CDK: 105101089(RAP1B)
BACU: 103018737 103019004(RAP1B)
LVE: 103083426(RAP1B) 103088976
OOR: 101284281(RAP1B)
ECB: 100052025(RAP1B)
EPZ: 103558687(RAP1B)
EAI: 106843586(RAP1B)
MYB: 102254910(RAP1B)
MYD: 102772411(RAP1B)
HAI: 109381707(RAP1B)
RSS: 109456591(RAP1B)
PALE: 102883778(RAP1B)
LAV: 100665185(RAP1B)
TMU: 101348129
MDO: 100014092(RAP1B)
SHR: 100920135(RAP1B)
OAA: 100079331(RAP1B)
GGA: 417840(RAP1B)
MGP: 100543810(RAP1B)
CJO: 107310547(RAP1B)
APLA: 101789925(RAP1B)
ACYG: 106046993(RAP1B)
TGU: 100223739(RAP1B)
GFR: 102042554(RAP1B)
FAB: 101812484(RAP1B)
PHI: 102099438(RAP1B)
PMAJ: 107204636(RAP1B)
CCW: 104698372(RAP1B)
FPG: 101924298(RAP1B)
FCH: 102047995(RAP1B)
CLV: 102083646(RAP1B)
EGZ: 104132908(RAP1B)
AAM: 106488632(RAP1B)
ASN: 102382819(RAP1B)
AMJ: 102561548(RAP1B)
PSS: 102444055(RAP1B)
CMY: 102947916(RAP1B)
CPIC: 101935007(RAP1B)
ACS: 100553457(rap1b)
PVT: 110075099(RAP1B)
PBI: 103064511(RAP1B)
GJA: 107105721(RAP1B)
XLA: 108713157 379883(rap1b.L)
XTR: 493557(rap1b)
NPR: 108804561(RAP1B)
DRE: 321107(rap1b)
SGH: 107553881(rap1b)
CCAR: 109067672 109072174(rap1b)
IPU: 100528315(rap1b)
AMEX: 103035254(rap1b)
TRU: 101070080
LCO: 104935802(rap1b)
MZE: 101471329
XMA: 102223832
PRET: 103459326(rap1b) 103464617
NFU: 107387503(rap1b)
CSEM: 103382506
LCF: 108901386(rap1b)
HCQ: 109532657(rap1b)
BPEC: 110161898(rap1b)
SASA: 106576640 106593497(RAP1B)
ELS: 105017798(rap1b) 105022336(rap1b)
SFM: 108920959 108936546(rap1b)
LCM: 102354357(RAP1B)
CMK: 103186117(rap1b)
SKO: 102804872
CRG: 105347969
LAK: 106163156
SHX: MS3_01653
AQU: 105313915
SCE: YGR152C(RSR1)
ERC: Ecym_1407
KMX: KLMA_60196(RSR1)
NCS: NCAS_0A01890(NCAS0A01890)
NDI: NDAI_0D03820(NDAI0D03820)
TPF: TPHA_0K01820(TPHA0K01820)
TBL: TBLA_0B00370(TBLA0B00370)
TDL: TDEL_0F02770(TDEL0F02770)
KAF: KAFR_0F03670(KAFR0F03670)
CAL: CAALFM_CR02140WA(RSR1)
CDU: CD36_27060(RSR1)
CAUR: QG37_00610
SLB: AWJ20_3825(RSR1)
DDI: DDB_G0291237(rapA)
DPP: DICPUDRAFT_59134(rapA)
DFA: DFA_03257 DFA_12095(rapA)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Zwartkruis FJ, Bos JL
  Title
Ras and Rap1: two highly related small GTPases with distinct function.
  Journal
Exp Cell Res 253:157-65 (1999)
DOI:10.1006/excr.1999.4695
Reference
PMID:3137530
  Authors
Pizon V, Lerosey I, Chardin P, Tavitian A
  Title
Nucleotide sequence of a human cDNA encoding a ras-related protein (rap1B).
  Journal
Nucleic Acids Res 16:7719 (1988)
  Sequence
[hsa:5908]

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