KEGG   ORTHOLOGY: K04377Help
Entry
K04377                      KO                                     

Name
MYC
Definition
Myc proto-oncogene protein
Pathway
ko04010  MAPK signaling pathway
ko04012  ErbB signaling pathway
ko04110  Cell cycle
ko04151  PI3K-Akt signaling pathway
ko04218  Cellular senescence
ko04310  Wnt signaling pathway
ko04350  TGF-beta signaling pathway
ko04390  Hippo signaling pathway
ko04391  Hippo signaling pathway - fly
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04630  JAK-STAT signaling pathway
ko04919  Thyroid hormone signaling pathway
ko05161  Hepatitis B
ko05163  Human cytomegalovirus infection
ko05166  HTLV-I infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05169  Epstein-Barr virus infection
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05205  Proteoglycans in cancer
ko05206  MicroRNAs in cancer
ko05210  Colorectal cancer
ko05213  Endometrial cancer
ko05216  Thyroid cancer
ko05219  Bladder cancer
ko05220  Chronic myeloid leukemia
ko05221  Acute myeloid leukemia
ko05222  Small cell lung cancer
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
ko05230  Central carbon metabolism in cancer
Disease
H00001  B lymphoblastic leukemia/lymphoma
H00002  T lymphoblastic leukemia/lymphoma
H00008  Burkitt lymphoma
H00010  Multiple myeloma
H00013  Small cell lung cancer
H00016  Oral cancer
H00025  Penile cancer
H00027  Ovarian cancer
H00028  Choriocarcinoma
H00036  Osteosarcoma
H00041  Kaposi sarcoma
H00048  Hepatocellular carcinoma
H00055  Laryngeal cancer
H01463  Mycosis fungoides
H01509  Tonsillar cancer
H01554  Fallopian tube cancer
H01667  Medulloblastoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04377  MYC; Myc proto-oncogene protein
   04012 ErbB signaling pathway
    K04377  MYC; Myc proto-oncogene protein
   04310 Wnt signaling pathway
    K04377  MYC; Myc proto-oncogene protein
   04350 TGF-beta signaling pathway
    K04377  MYC; Myc proto-oncogene protein
   04390 Hippo signaling pathway
    K04377  MYC; Myc proto-oncogene protein
   04391 Hippo signaling pathway -fly
    K04377  MYC; Myc proto-oncogene protein
   04630 Jak-STAT signaling pathway
    K04377  MYC; Myc proto-oncogene protein
   04151 PI3K-Akt signaling pathway
    K04377  MYC; Myc proto-oncogene protein
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K04377  MYC; Myc proto-oncogene protein
   04218 Cellular senescence
    K04377  MYC; Myc proto-oncogene protein
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K04377  MYC; Myc proto-oncogene protein
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    K04377  MYC; Myc proto-oncogene protein
 09160 Human Diseases
  09161 Cancers
   05200 Pathways in cancer
    K04377  MYC; Myc proto-oncogene protein
   05230 Central carbon metabolism in cancer
    K04377  MYC; Myc proto-oncogene protein
   05202 Transcriptional misregulation in cancers
    K04377  MYC; Myc proto-oncogene protein
   05206 MicroRNAs in cancer
    K04377  MYC; Myc proto-oncogene protein
   05205 Proteoglycans in cancer
    K04377  MYC; Myc proto-oncogene protein
   05210 Colorectal cancer
    K04377  MYC; Myc proto-oncogene protein
   05225 Hepatocellular carcinoma
    K04377  MYC; Myc proto-oncogene protein
   05226 Gastric cancer
    K04377  MYC; Myc proto-oncogene protein
   05216 Thyroid cancer
    K04377  MYC; Myc proto-oncogene protein
   05221 Acute myeloid leukemia
    K04377  MYC; Myc proto-oncogene protein
   05220 Chronic myeloid leukemia
    K04377  MYC; Myc proto-oncogene protein
   05219 Bladder cancer
    K04377  MYC; Myc proto-oncogene protein
   05213 Endometrial cancer
    K04377  MYC; Myc proto-oncogene protein
   05224 Breast cancer
    K04377  MYC; Myc proto-oncogene protein
   05222 Small cell lung cancer
    K04377  MYC; Myc proto-oncogene protein
  09167 Infectious diseases
   05166 HTLV-I infection
    K04377  MYC; Myc proto-oncogene protein
   05161 Hepatitis B
    K04377  MYC; Myc proto-oncogene protein
   05163 Human cytomegalovirus infection
    K04377  MYC; Myc proto-oncogene protein
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04377  MYC; Myc proto-oncogene protein
   05169 Epstein-Barr virus infection
    K04377  MYC; Myc proto-oncogene protein
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04377  MYC; Myc proto-oncogene protein
   03019 Messenger RNA Biogenesis
    K04377  MYC; Myc proto-oncogene protein
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
   Cell cycle controlling factors, Myc
    K04377  MYC; Myc proto-oncogene protein
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   Factors involved in mRNA localization
    Factors that have mRNA localization signals
     K04377  MYC; Myc proto-oncogene protein
BRITE hierarchy
Genes
HSA: 4609(MYC)
PTR: 464393(MYC)
PPS: 103786410(MYC)
GGO: 101137026(MYC)
PON: 100456735(MYC)
NLE: 100589322(MYC)
MCC: 694626(MYC)
MCF: 102127966(MYC)
CSAB: 103237430(MYC)
RRO: 104674798(MYC)
RBB: 108528761(MYC)
CJC: 100407754(MYC)
SBQ: 101047066(MYC)
MMU: 17869(Myc)
RNO: 24577(Myc)
NGI: 103743920(Myc)
HGL: 101704740(Myc)
CCAN: 109699943(Myc)
OCU: 100327265(MYC)
TUP: 102501999(MYC)
CFA: 403924(MYC)
AML: 100464396(MYC)
UMR: 103661697(MYC)
ORO: 101369253(MYC)
FCA: 100379628(MYC)
PTG: 102954147(MYC)
AJU: 106976895(MYC)
BTA: 511077(MYC)
BOM: 102274304(MYC)
BIU: 109568594(MYC)
PHD: 102328645
CHX: 102171262(MYC)
OAS: 443447(MYC)
SSC: 448810(MYC)
CFR: 102511086
CDK: 105096445(MYC)
BACU: 103016933(MYC)
LVE: 103089962(MYC)
OOR: 101274490(MYC)
ECB: 100068097(MYC)
EPZ: 103567860(MYC)
EAI: 106824829(MYC)
MYB: 102257498(MYC)
MYD: 102758544(MYC)
HAI: 109383211(MYC)
RSS: 109443375(MYC)
PALE: 102895524(MYC)
LAV: 100665874(MYC)
TMU: 101349786
MDO: 100032344(MYC)
SHR: 100921308
OAA: 100079391(MYC)
GGA: 420332(MYC)
MGP: 100547931(MYC)
CJO: 107310561(MYC)
APLA: 101803370(MYC)
ACYG: 106038450(MYC)
TGU: 100219849(MYC)
GFR: 102037262(MYC)
FAB: 101819732(MYC)
PHI: 102108851(MYC)
PMAJ: 107200993(MYC)
CCW: 104692644(MYC)
FPG: 101923426(MYC)
FCH: 102056832(MYC)
CLV: 102085948(MYC)
EGZ: 104134424(MYC)
AAM: 106496220(MYC)
ASN: 102370393(MYC)
AMJ: 102561083(MYC)
PSS: 102449445(MYC)
CMY: 102943256(MYC)
CPIC: 101945997(MYC)
ACS: 100558533(myc)
PVT: 110085305(MYC)
PBI: 103057606(MYC)
GJA: 107122472(MYC)
XLA: 379052(myc.S) 399315(myc.L)
XTR: 395024(myc)
NPR: 108788968(MYC)
DRE: 393141(mycb)
IPU: 100304504(myc) 108268289(mycb) 108272607
TRU: 101072742 653028(myc)
NCC: 104954577(myc) 104958803
OLA: 101164933(myc) 101171524(c-myc17)
HCQ: 109521513 109521839(myc)
BPEC: 110168965 110170064(myc)
SASA: 100380346(myc2) 100380531(myc) 106568625(myc) 106578682 106590162(c-myc)
SFM: 108937539(myc) 108942150
LCM: 102357079(MYC) 102359985
CMK: 103173257 103185113(myc)
SPU: 373385
APLC: 110980035
SKO: 100303478(myc)
DME: Dmel_CG10798(Myc)
DSI: Dsimw501_GD16640(Dsim_GD16640)
MDE: 101887976
AAG: 5575983
AME: 100576392
BIM: 100749108
BTER: 100650167
SOC: 105195393
PBAR: 105430909
CFO: 105258327
LHU: 105676895
NVI: 100679741
NVL: 108561707
BMOR: 100862782(myc)
PMAC: 106718960
PRAP: 110995053
PXY: 105385775
ZNE: 110831645
CRG: 105337948
MYI: 110459724
LAK: 106173899
HMG: 100199110(myc2)
MBR: MONBRDRAFT_33423(MbMyc)
VG: 1491913(Amvgp1) 1491953(ACVgp1)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
PMID:6462227
  Authors
Stanton LW, Fahrlander PD, Tesser PM, Marcu KB
  Title
Nucleotide sequence comparison of normal and translocated murine c-myc genes.
  Journal
Nature 310:423-5 (1984)
DOI:10.1038/310423a0
  Sequence
[mmu:17869]
Reference
  Authors
Bellosta P, Hulf T, Balla Diop S, Usseglio F, Pradel J, Aragnol D, Gallant P
  Title
Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development.
  Journal
Proc Natl Acad Sci U S A 102:11799-804 (2005)
DOI:10.1073/pnas.0408945102
  Sequence

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