KEGG   ORTHOLOGY: K04383Help
Entry
K04383                      KO                                     

Name
IL1A
Definition
interleukin 1 alpha
Pathway
ko04010  MAPK signaling pathway
ko04060  Cytokine-cytokine receptor interaction
ko04217  Necroptosis
ko04218  Cellular senescence
ko04380  Osteoclast differentiation
ko04640  Hematopoietic cell lineage
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko04940  Type I diabetes mellitus
ko05020  Prion diseases
ko05132  Salmonella infection
ko05133  Pertussis
ko05140  Leishmaniasis
ko05152  Tuberculosis
ko05162  Measles
ko05164  Influenza A
ko05321  Inflammatory bowel disease (IBD)
ko05323  Rheumatoid arthritis
ko05332  Graft-versus-host disease
ko05418  Fluid shear stress and atherosclerosis
Disease
H00084  Graft-versus-host disease
H01492  Systemic sclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04383  IL1A; interleukin 1 alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04383  IL1A; interleukin 1 alpha
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K04383  IL1A; interleukin 1 alpha
   04218 Cellular senescence
    K04383  IL1A; interleukin 1 alpha
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K04383  IL1A; interleukin 1 alpha
  09158 Development
   04380 Osteoclast differentiation
    K04383  IL1A; interleukin 1 alpha
 09160 Human Diseases
  09162 Immune diseases
   05323 Rheumatoid arthritis
    K04383  IL1A; interleukin 1 alpha
   05321 Inflammatiory bowel disease (IBD)
    K04383  IL1A; interleukin 1 alpha
   05332 Graft-versus-host disease
    K04383  IL1A; interleukin 1 alpha
  09163 Neurodegenerative diseases
   05020 Prion diseases
    K04383  IL1A; interleukin 1 alpha
  09165 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K04383  IL1A; interleukin 1 alpha
  09166 Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K04383  IL1A; interleukin 1 alpha
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04383  IL1A; interleukin 1 alpha
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04383  IL1A; interleukin 1 alpha
  09167 Infectious diseases
   05132 Salmonella infection
    K04383  IL1A; interleukin 1 alpha
   05133 Pertussis
    K04383  IL1A; interleukin 1 alpha
   05152 Tuberculosis
    K04383  IL1A; interleukin 1 alpha
   05162 Measles
    K04383  IL1A; interleukin 1 alpha
   05164 Influenza A
    K04383  IL1A; interleukin 1 alpha
   05140 Leishmaniasis
    K04383  IL1A; interleukin 1 alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K04383  IL1A; interleukin 1 alpha
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Interleukins
   K04383  IL1A; interleukin 1 alpha
BRITE hierarchy
Other DBs
GO: 0005149
Genes
HSA: 3552(IL1A)
PTR: 470485(IL1A)
PPS: 100994286(IL1A)
GGO: 101129849(IL1A)
PON: 100454009(IL1A)
NLE: 100587009(IL1A)
MCC: 700193(IL1A)
MCF: 101926546(IL1A)
CSAB: 103241279(IL1A)
RRO: 104672546(IL1A)
RBB: 108541808(IL1A)
CJC: 100406401(IL1A)
SBQ: 101033360(IL1A)
MMU: 16175(Il1a)
RNO: 24493(Il1a)
CGE: 100769260(Il1a)
NGI: 103739898(Il1a)
HGL: 101703933(Il1a)
CCAN: 109702296(Il1a)
OCU: 100009250(IL1A)
TUP: 102475560(IL1A)
CFA: 403782(IL1A)
AML: 100481122(IL1A)
UMR: 103671864(IL1A)
ORO: 101382716(IL1A)
FCA: 493944(IL1A)
PTG: 102951574(IL1A)
AJU: 106976018(IL1A)
BTA: 281250(IL1A)
BOM: 102282330(IL1A)
BIU: 109566132(IL1A)
PHD: 102329431(IL1A)
CHX: 100861289(IL1A)
OAS: 443404(IL1A)
SSC: 397094(IL1A)
CFR: 102521743(IL1A)
CDK: 105093151(IL1A)
BACU: 103008155(IL1A)
LVE: 103090247(IL1A)
OOR: 101272616(IL1A)
ECB: 100064969(IL1A)
EPZ: 103559673(IL1A)
EAI: 106838556(IL1A)
MYB: 102251877(IL1A)
MYD: 102770100(IL1A)
HAI: 109393526(IL1A)
RSS: 109435856(IL1A)
PALE: 102892998(IL1A)
LAV: 100675032(IL1A)
TMU: 101359155
MDO: 103105940(IL1A)
SHR: 105749132(IL1A)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3486405
  Authors
Furutani Y, Notake M, Fukui T, Ohue M, Nomura H, Yamada M, Nakamura S
  Title
Complete nucleotide sequence of the gene for human interleukin 1 alpha.
  Journal
Nucleic Acids Res 14:3167-79 (1986)
DOI:10.1093/nar/14.8.3167
  Sequence
[hsa:3552]

KEGG   ORTHOLOGY: K04519Help
Entry
K04519                      KO                                     

Name
IL1B
Definition
interleukin 1 beta
Pathway
ko01523  Antifolate resistance
ko04010  MAPK signaling pathway
ko04060  Cytokine-cytokine receptor interaction
ko04064  NF-kappa B signaling pathway
ko04217  Necroptosis
ko04380  Osteoclast differentiation
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04623  Cytosolic DNA-sensing pathway
ko04625  C-type lectin receptor signaling pathway
ko04640  Hematopoietic cell lineage
ko04657  IL-17 signaling pathway
ko04659  Th17 cell differentiation
ko04668  TNF signaling pathway
ko04750  Inflammatory mediator regulation of TRP channels
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko04940  Type I diabetes mellitus
ko05010  Alzheimer disease
ko05020  Prion diseases
ko05132  Salmonella infection
ko05133  Pertussis
ko05134  Legionellosis
ko05140  Leishmaniasis
ko05142  Chagas disease (American trypanosomiasis)
ko05143  African trypanosomiasis
ko05144  Malaria
ko05146  Amoebiasis
ko05152  Tuberculosis
ko05162  Measles
ko05163  Human cytomegalovirus infection
ko05164  Influenza A
ko05168  Herpes simplex infection
ko05321  Inflammatory bowel disease (IBD)
ko05323  Rheumatoid arthritis
ko05332  Graft-versus-host disease
ko05418  Fluid shear stress and atherosclerosis
Disease
H01492  Systemic sclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04519  IL1B; interleukin 1 beta
   04064 NF-kappa B signaling pathway
    K04519  IL1B; interleukin 1 beta
   04668 TNF signaling pathway
    K04519  IL1B; interleukin 1 beta
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04519  IL1B; interleukin 1 beta
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K04519  IL1B; interleukin 1 beta
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K04519  IL1B; interleukin 1 beta
   04620 Toll-like receptor signaling pathway
    K04519  IL1B; interleukin 1 beta
   04621 NOD-like receptor signaling pathway
    K04519  IL1B; interleukin 1 beta
   04623 Cytosolic DNA-sensing pathway
    K04519  IL1B; interleukin 1 beta
   04625 C-type lectin receptor signaling pathway
    K04519  IL1B; interleukin 1 beta
   04659 Th17 cell differentiation
    K04519  IL1B; interleukin 1 beta
   04657 IL-17 signaling pathway
    K04519  IL1B; interleukin 1 beta
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K04519  IL1B; interleukin 1 beta
  09158 Development
   04380 Osteoclast differentiation
    K04519  IL1B; interleukin 1 beta
 09160 Human Diseases
  09162 Immune diseases
   05323 Rheumatoid arthritis
    K04519  IL1B; interleukin 1 beta
   05321 Inflammatiory bowel disease (IBD)
    K04519  IL1B; interleukin 1 beta
   05332 Graft-versus-host disease
    K04519  IL1B; interleukin 1 beta
  09163 Neurodegenerative diseases
   05010 Alzheimer disease
    K04519  IL1B; interleukin 1 beta
   05020 Prion diseases
    K04519  IL1B; interleukin 1 beta
  09165 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K04519  IL1B; interleukin 1 beta
  09166 Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K04519  IL1B; interleukin 1 beta
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04519  IL1B; interleukin 1 beta
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04519  IL1B; interleukin 1 beta
  09167 Infectious diseases
   05132 Salmonella infection
    K04519  IL1B; interleukin 1 beta
   05133 Pertussis
    K04519  IL1B; interleukin 1 beta
   05134 Legionellosis
    K04519  IL1B; interleukin 1 beta
   05152 Tuberculosis
    K04519  IL1B; interleukin 1 beta
   05162 Measles
    K04519  IL1B; interleukin 1 beta
   05164 Influenza A
    K04519  IL1B; interleukin 1 beta
   05168 Herpes simplex infection
    K04519  IL1B; interleukin 1 beta
   05163 Human cytomegalovirus infection
    K04519  IL1B; interleukin 1 beta
   05146 Amoebiasis
    K04519  IL1B; interleukin 1 beta
   05144 Malaria
    K04519  IL1B; interleukin 1 beta
   05140 Leishmaniasis
    K04519  IL1B; interleukin 1 beta
   05142 Chagas disease (American trypanosomiasis)
    K04519  IL1B; interleukin 1 beta
   05143 African trypanosomiasis
    K04519  IL1B; interleukin 1 beta
  09168 Drug resistance
   01523 Antifolate resistance
    K04519  IL1B; interleukin 1 beta
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K04519  IL1B; interleukin 1 beta
   00536 Glycosaminoglycan binding proteins
    K04519  IL1B; interleukin 1 beta
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Interleukins
   K04519  IL1B; interleukin 1 beta
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Cytokines
   K04519  IL1B; interleukin 1 beta
BRITE hierarchy
Other DBs
GO: 0005149
Genes
HSA: 3553(IL1B)
PTR: 450200(IL1B)
PPS: 100993613(IL1B)
GGO: 101130571(IL1B)
PON: 100454379(IL1B)
NLE: 100587357(IL1B)
MCC: 704701(IL1B)
MCF: 102119749(IL1B)
CSAB: 103241278(IL1B)
RRO: 104672547(IL1B)
RBB: 108541809(IL1B)
CJC: 100406769(IL1B)
SBQ: 101033664(IL1B)
MMU: 16176(Il1b)
RNO: 24494(Il1b)
CGE: 100775079(Il1b)
NGI: 103739899(Il1b)
HGL: 101704309(Il1b)
CCAN: 109701168(Il1b)
OCU: 100008990(IL1B)
TUP: 102475138(IL1B)
CFA: 403974(IL1B)
AML: 100480874(IL1B)
UMR: 103671495(IL1B)
ORO: 101383005(IL1B)
FCA: 768274(IL1B)
PTG: 102951272(IL1B)
AJU: 106976013(IL1B)
BTA: 281251(IL1B)
BOM: 102282890(IL1B)
BIU: 109566133(IL1B)
PHD: 102329073(IL1B)
CHX: 100860816(IL1B)
OAS: 443539(IL1B)
SSC: 396565(IL1B2) 397122(IL1B)
CFR: 102521979(IL1B)
CDK: 105093155(IL1B)
BACU: 103008438(IL1B)
LVE: 103090784(IL1B)
OOR: 101284892(IL1B)
ECB: 100034237(IL1B) 100052414(IL1B)
EPZ: 103544835(IL1B)
EAI: 106838557(IL1B)
MYB: 102251576(IL1B)
MYD: 102769803(IL1B)
HAI: 109393524(IL1B)
RSS: 109435855(IL1B)
PALE: 102893238(IL1B)
LAV: 100674746(IL1B)
TMU: 101359415(IL1B)
MDO: 100026024(IL1B)
SHR: 100922350(IL1B)
OAA: 103165286(IL1B)
GGA: 395196(IL1B)
MGP: 100034741(IL1RN)
CJO: 107323637(IL1B)
TGU: 100227014(IL1B)
GFR: 102041770(IL1B)
FAB: 101819115(IL1B)
PHI: 102108659(IL1B)
PMAJ: 107213896
CCW: 104683159
FPG: 101924267
FCH: 102050776(IL1B)
CLV: 102090585(IL1B)
EGZ: 104132895(IL1RN)
ASN: 102369595(IL1B)
AMJ: 102570262(IL1B)
PSS: 102448244(IL-1beta)
CMY: 102933972
CPIC: 101943587(IL1B)
PVT: 110072197(IL1B)
PBI: 103055254(IL1B)
GJA: 107118765
XLA: 108711577(il1b.L) 108711578 373606(il1b.S)
XTR: 100487038(il1b)
DRE: 405770(il1b)
IPU: 100304696(il1b) 100304697(il1b)
TRU: 101080001(il1b)
LCO: 104923462(IL-1beta)
NCC: 104948030 104955090(il1b)
OLA: 101169209
NFU: 107386182
HCQ: 109513432
BPEC: 110166705 110172087(il1b)
SFM: 108932396(il1b) 108940319
LCM: 102364535
CMK: 103187802
 » show all
TaxonomyKoalaUniProt
Reference
PMID:6083565
  Authors
Auron PE, Webb AC, Rosenwasser LJ, Mucci SF, Rich A, Wolff SM, Dinarello CA
  Title
Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.
  Journal
Proc Natl Acad Sci U S A 81:7907-11 (1984)
DOI:10.1073/pnas.81.24.7907
  Sequence
[hsa:3553]

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