KEGG   ORTHOLOGY: K04390Help
Entry
K04390                      KO                                     

Name
TNFRSF6, FAS, CD95
Definition
tumor necrosis factor receptor superfamily member 6
Pathway
ko01524  Platinum drug resistance
ko04010  MAPK signaling pathway
ko04060  Cytokine-cytokine receptor interaction
ko04115  p53 signaling pathway
ko04210  Apoptosis
ko04217  Necroptosis
ko04650  Natural killer cell mediated cytotoxicity
ko04668  TNF signaling pathway
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko04940  Type I diabetes mellitus
ko05010  Alzheimer disease
ko05142  Chagas disease (American trypanosomiasis)
ko05143  African trypanosomiasis
ko05161  Hepatitis B
ko05162  Measles
ko05163  Human cytomegalovirus infection
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05320  Autoimmune thyroid disease
ko05330  Allograft rejection
ko05332  Graft-versus-host disease
Disease
H00005  Chronic lymphocytic leukemia (CLL)
H00007  Hodgkin lymphoma
H00009  Adult T-cell leukemia
H00017  Esophageal cancer
H01463  Mycosis fungoides
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   04668 TNF signaling pathway
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   04217 Necroptosis
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   04115 p53 signaling pathway
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
 09160 Human Diseases
  09161 Cancers
   05200 Pathways in cancer
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05205 Proteoglycans in cancer
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
  09162 Immune diseases
   05320 Autoimmune thyroid disease
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05330 Allograft rejection
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05332 Graft-versus-host disease
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
  09163 Neurodegenerative diseases
   05010 Alzheimer disease
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
  09166 Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
  09167 Infectious diseases
   05162 Measles
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05164 Influenza A
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05161 Hepatitis B
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05168 Herpes simplex infection
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05163 Human cytomegalovirus infection
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05165 Human papillomavirus infection
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05142 Chagas disease (American trypanosomiasis)
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   05143 African trypanosomiasis
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
  09168 Drug resistance
   01524 Platinum drug resistance
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
   04090 CD Molecules
    K04390  CD95, FAS; tumor necrosis factor receptor superfamily, member 6
Cytokine receptors [BR:ko04050]
 Tumor necrosis factor receptors
  TNF receptor superfamily
   K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
CD molecules [BR:ko04090]
 Proteins
  K04390  CD95, FAS; tumor necrosis factor receptor superfamily, member 6
BRITE hierarchy
Other DBs
GO: 0005031
Genes
HSA: 355(FAS)
PTR: 738331(FAS)
PPS: 100988526(FAS)
GGO: 101152441(FAS)
NLE: 100580318(FAS)
MCC: 574332(FAS)
MCF: 102140989(FAS)
CSAB: 103216224(FAS)
RRO: 104675147(FAS)
RBB: 108526609(FAS)
CJC: 100397803(FAS)
SBQ: 101035635(FAS)
MMU: 14102(Fas)
RNO: 246097(Fas)
CGE: 100762537(Fas)
NGI: 103738053(Fas)
HGL: 101704746(Fas)
CCAN: 109691142(Fas)
OCU: 100008609(FAS)
TUP: 102476587(FAS)
CFA: 486469(FAS)
AML: 100473767(FAS)
UMR: 103661934(FAS)
ORO: 101369551(FAS)
FCA: 493881(FAS)
PTG: 102958442(FAS)
AJU: 106980953(FAS)
BTA: 282488(FAS)
BOM: 102273906(FAS)
BIU: 109579171(FAS)
PHD: 102339498(FAS)
CHX: 102180451(FAS)
OAS: 100144426(FAS)
SSC: 396826(FAS)
CFR: 102518538(FAS)
CDK: 105102832(FAS)
BACU: 103020508(FAS)
LVE: 103080104(FAS)
OOR: 101284022(FAS)
ECB: 100071639(FAS)
EPZ: 103558124(FAS)
EAI: 106822180(FAS)
MYB: 102259838(FAS)
MYD: 102760302(FAS)
HAI: 109377126(FAS)
RSS: 109450766(FAS)
PALE: 102879561(FAS)
LAV: 100657715(FAS)
TMU: 101346704
SHR: 105749219
OAA: 100083180
GGA: 395274(FAS)
MGP: 100550139(FAS)
CJO: 107315904(FAS)
APLA: 101796331(FAS)
ACYG: 106030038(FAS)
TGU: 100225721(FAS)
GFR: 102033034(FAS)
FAB: 101806294(FAS)
PHI: 102102426(FAS)
PMAJ: 107206851(FAS)
CCW: 104696515(FAS)
FPG: 101911760(FAS)
FCH: 102048640(FAS)
CLV: 102087399(FAS)
EGZ: 104129042(FAS)
AAM: 106487830(FAS)
ASN: 102375471(FAS)
AMJ: 102562734(FAS)
PSS: 102463316(FAS)
CMY: 102944566(FAS)
CPIC: 101938109(FAS)
ACS: 100551688(fas)
PVT: 110083121(FAS)
PBI: 103050181
GJA: 107121652(FAS)
XTR: 100124750(fas)
DRE: 768248(fas)
IPU: 100304627
AMEX: 103046657
TRU: 101067230
LCO: 104929632
NCC: 104956661
MZE: 101463633
OLA: 101172757
XMA: 102232209
PRET: 103476792
NFU: 107376035
CSEM: 103387676
LCF: 108897286(fas)
HCQ: 109528779
BPEC: 110157042
SASA: 100380364(tnr6) 106577010
ELS: 105022722
SFM: 108939520(fas)
LCM: 102349412(FAS)
CMK: 103180778(fas)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1713127
  Authors
Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S, Sameshima M, Hase A, Seto Y, Nagata S
  Title
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis.
  Journal
Cell 66:233-43 (1991)
DOI:10.1016/0092-8674(91)90614-5
  Sequence
[hsa:355]
Reference
  Authors
Riccio M, Carnevale G, Cardinale V, Gibellini L, De Biasi S, Pisciotta A, Carpino G, Gentile R, Berloco PB, Brunelli R, Bastianelli C, Napoletano C, Cantafora A, Cossarizza A, Gaudio E, Alvaro D, De Pol A
  Title
The Fas/Fas ligand apoptosis pathway underlies immunomodulatory properties of human biliary tree stem/progenitor cells.
  Journal
J Hepatol 61:1097-105 (2014)
DOI:10.1016/j.jhep.2014.06.016
  Sequence
[hsa:355]

DBGET integrated database retrieval system