KEGG   ORTHOLOGY: K04412Help
Entry
K04412                      KO                                     

Name
STK3, MST2
Definition
serine/threonine kinase 3
Pathway
ko04010  MAPK signaling pathway
ko04214  Apoptosis - fly
ko04390  Hippo signaling pathway
ko04391  Hippo signaling pathway - fly
ko04392  Hippo signaling pathway - multiple species
Module
M00683  Hippo signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04412  STK3, MST2; serine/threonine kinase 3
   04390 Hippo signaling pathway
    K04412  STK3, MST2; serine/threonine kinase 3
   04391 Hippo signaling pathway -fly
    K04412  STK3, MST2; serine/threonine kinase 3
   04392 Hippo signaling pathway - multiple species
    K04412  STK3, MST2; serine/threonine kinase 3
 09140 Cellular Processes
  09143 Cell growth and death
   04214 Apoptosis - fly
    K04412  STK3, MST2; serine/threonine kinase 3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04412  STK3, MST2; serine/threonine kinase 3
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00683  Hippo signaling
     K04412  STK3, MST2; serine/threonine kinase 3
Protein kinases [BR:ko01001]
 Serine/threonine kinases: STE group
  STE20 family
   K04412  STK3, MST2; serine/threonine kinase 3
BRITE hierarchy
Genes
HSA: 6788(STK3)
PTR: 472829(STK3)
PPS: 100992217(STK3)
GGO: 101139712(STK3)
PON: 100172589(STK3)
NLE: 100587096(STK3)
MCC: 707425(STK3)
MCF: 101925889(STK3)
CSAB: 103237196(STK3)
RRO: 104679882(STK3)
RBB: 108542507(STK3)
CJC: 100387692(STK3)
SBQ: 101044498(STK3)
MMU: 56274(Stk3)
RNO: 65189(Stk3)
CGE: 100763795(Stk3)
NGI: 103732823(Stk3)
HGL: 101715099(Stk3)
CCAN: 109688653(Stk3)
OCU: 100357564(STK3)
TUP: 102498416(STK3)
CFA: 475045(STK3)
AML: 100464802(STK3)
UMR: 103661633(STK3)
ORO: 101364004(STK3)
FCA: 101081440(STK3)
PTG: 102972219(STK3)
AJU: 106983846(STK3)
BTA: 533815(STK3)
BOM: 102270134(STK3)
BIU: 109568496(STK3)
PHD: 102329211(STK3)
CHX: 102191439(STK3)
OAS: 101106085(STK3)
SSC: 100524741(STK3)
CFR: 102508082(STK3)
CDK: 105090573(STK3)
BACU: 103012811(STK3)
LVE: 103072304(STK3)
OOR: 101278418(STK3)
ECB: 100060508(STK3)
EPZ: 103555870(STK3)
EAI: 106826995 106835440(STK3)
MYB: 102253240(STK3)
MYD: 102759803(STK3)
HAI: 109382813(STK3)
RSS: 109461425(STK3)
PALE: 102897363(STK3)
LAV: 100670509(STK3)
TMU: 101355756
MDO: 100030422
OAA: 100083303
GGA: 425375(STK3)
MGP: 100547673(STK3)
CJO: 107310441(STK3)
APLA: 101796457(STK3)
ACYG: 106035282(STK3)
TGU: 100228853(STK3)
GFR: 102041006(STK3)
FAB: 101814337(STK3)
PHI: 102108615(STK3)
PMAJ: 107200357(STK3)
CCW: 104692727(STK3)
FPG: 101919634(STK3)
FCH: 102052175(STK3)
CLV: 102088301(STK3)
EGZ: 104125823(STK3)
AAM: 106483864(STK3)
ASN: 102371773(STK3)
AMJ: 102562825(STK3)
PSS: 102463813(STK3) 106732081
CMY: 102930624(STK3)
CPIC: 101939350(STK3) 101951054
ACS: 100563011(stk3)
PVT: 110074755(STK3)
PBI: 103064033(STK3)
GJA: 107105835(STK3)
XLA: 108719348 432210(stk3.S)
XTR: 100036637(stk3)
NPR: 108789153(STK3)
DRE: 324125(stk3)
CCAR: 109091699
IPU: 108256932(stk3)
AMEX: 103027492(stk3)
TRU: 101074579(stk3)
LCO: 104918642(stk3)
NCC: 104942286(stk3)
MZE: 101476981
OLA: 101155570
XMA: 102233124(stk3)
PRET: 103472439(stk3)
NFU: 107394672(stk3)
CSEM: 103394381
LCF: 108898178(stk3)
HCQ: 109509241 109514570(stk3)
BPEC: 110167165(stk3)
ELS: 105027710
SFM: 108940739(stk3)
CMK: 103179698(stk3)
CIN: 101242287(stk3)
SPU: 576378
APLC: 110987983
SKO: 100377733
DME: Dmel_CG11228(hpo)
DSI: Dsimw501_GD25317(Dsim_GD25317)
AAG: 5568100
AME: 410208
BIM: 100740961
BTER: 100651532
SOC: 105195909
AEC: 105153384
ACEP: 105619493
PBAR: 105425238
HST: 105187019
CFO: 105253054
LHU: 105675764
PGC: 109855955
NVI: 100120481
TCA: 658552
NVL: 108564863
BMOR: 100144578(HPO)
PMAC: 106710906
PRAP: 111000794
PXY: 105390538
DNX: 107166337
ZNE: 110827894
FCD: 110852052
CEL: CELE_C24A8.4(cst-2) CELE_F14H12.4(cst-1)
CBR: CBG14395(Cbr-cst-1)
BMY: Bm1_32140
TSP: Tsp_03757
CRG: 105340117
MYI: 110443542
OBI: 106870147
LAK: 106161431
SHX: MS3_06797
EPA: 110235432
ADF: 107357484
AQU: 100631652
BNA: 106403414
DDI: DDB_G0273121(pakH-1) DDB_G0273865(pakH-2)
DFA: DFA_02105(pakH-2)
EHI: EHI_156670(242.t00007)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Chan EH, Nousiainen M, Chalamalasetty RB, Schafer A, Nigg EA, Sillje HH
  Title
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1.
  Journal
Oncogene 24:2076-86 (2005)
DOI:10.1038/sj.onc.1208445
  Sequence
[hsa:6788]
Reference
  Authors
Udan RS, Kango-Singh M, Nolo R, Tao C, Halder G
  Title
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway.
  Journal
Nat Cell Biol 5:914-20 (2003)
DOI:10.1038/ncb1050
Reference
PMID:8566796
  Authors
Creasy CL, Chernoff J
  Title
Cloning and characterization of a member of the MST subfamily of Ste20-like kinases.
  Journal
Gene 167:303-6 (1995)
DOI:10.1016/0378-1119(95)00653-2
  Sequence
[hsa:6788]

KEGG   ORTHOLOGY: K04411Help
Entry
K04411                      KO                                     

Name
STK4, MST1
Definition
serine/threonine kinase 4
Pathway
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04068  FoxO signaling pathway
ko05200  Pathways in cancer
ko05223  Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K04411  STK4, MST1; serine/threonine kinase 4
   04010 MAPK signaling pathway
    K04411  STK4, MST1; serine/threonine kinase 4
   04068 FoxO signaling pathway
    K04411  STK4, MST1; serine/threonine kinase 4
 09160 Human Diseases
  09161 Cancers
   05200 Pathways in cancer
    K04411  STK4, MST1; serine/threonine kinase 4
   05223 Non-small cell lung cancer
    K04411  STK4, MST1; serine/threonine kinase 4
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04411  STK4, MST1; serine/threonine kinase 4
Protein kinases [BR:ko01001]
 Serine/threonine kinases: STE group
  STE20 family
   K04411  STK4, MST1; serine/threonine kinase 4
BRITE hierarchy
Genes
HSA: 6789(STK4)
PTR: 458275(STK4)
PPS: 100983482(STK4)
GGO: 101129803(STK4)
PON: 100438713(STK4)
NLE: 100599164(STK4)
MCC: 717730(STK4)
MCF: 102115733(STK4)
CSAB: 103245516(STK4)
RRO: 104678859(STK4)
RBB: 108533369(STK4)
CJC: 100407296(STK4)
SBQ: 101046861(STK4)
MMU: 58231(Stk4)
RNO: 311622(Stk4)
CGE: 100757702(Stk4)
NGI: 103748401(Stk4)
HGL: 101704401(Stk4)
CCAN: 109681302(Stk4)
OCU: 100358822(STK4)
TUP: 102481933(STK4)
CFA: 477240(STK4)
AML: 100466725(STK4)
UMR: 103669878(STK4)
ORO: 101382383(STK4)
FCA: 101091185(STK4)
PTG: 102954711(STK4)
AJU: 106968996(STK4)
BTA: 514886(STK4)
BOM: 102270413(STK4)
BIU: 109567475(STK4)
PHD: 102338334(STK4)
CHX: 102185193(STK4)
OAS: 101110437(STK4)
SSC: 100517317(STK4)
CFR: 102514045(STK4)
CDK: 105087816(STK4)
BACU: 103007242(STK4)
LVE: 103079150(STK4)
OOR: 101269962(STK4)
ECB: 100070861(STK4)
EPZ: 103557216(STK4)
EAI: 106843012(STK4)
MYB: 102249534(STK4)
MYD: 102769615(STK4)
HAI: 109379970(STK4)
RSS: 109457082(STK4)
PALE: 102881410(STK4)
LAV: 100659146(STK4)
TMU: 101351731
MDO: 100024136(STK4)
SHR: 100929626(STK4)
OAA: 100088971
GGA: 419187(STK4)
MGP: 100550208
CJO: 107322948(STK4)
APLA: 101789768(STK4)
ACYG: 106041054(STK4)
TGU: 100225740(STK4)
GFR: 102031383(STK4)
FAB: 101805689(STK4)
PHI: 102106810(STK4)
PMAJ: 107213380(STK4)
CCW: 104687877(STK4)
FPG: 101914167(STK4)
FCH: 102055434(STK4)
CLV: 102097446(STK4)
EGZ: 104124962(STK4)
AAM: 106500122(STK4)
ASN: 102385000(STK4)
AMJ: 102569590(STK4)
PSS: 102454656(STK4)
CMY: 102930227(STK4)
CPIC: 101952056(STK4)
ACS: 100555926(stk4)
PVT: 110076762(STK4)
PBI: 103054805(STK4)
GJA: 107116155(STK4)
XLA: 398925(stk4.S) 779226(stk4)
XTR: 394860(stk4)
NPR: 108793685
IPU: 108271901(stk4)
AMEX: 103038106
MZE: 101482544
OLA: 101175466
XMA: 102225343
PRET: 103464816
NFU: 107384961
CSEM: 103386792
LCF: 108901469
HCQ: 109522371
BPEC: 110163440
SASA: 100380329(stk4)
ELS: 105010087
SFM: 108928433(stk4)
LCM: 102354634(STK4)
CMK: 103190959(stk4)
DDI: DDB_G0284181(krsA)
DFA: DFA_04596(krsA)
NGD: NGA_0179701(STK3) NGA_0179702(STK3)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Feig LA, Buchsbaum RJ
  Title
Cell signaling: life or death decisions of ras proteins.
  Journal
Curr Biol 12:R259-61 (2002)
DOI:10.1016/S0960-9822(02)00787-X

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