KEGG   ORTHOLOGY: K04428
Entry
K04428                      KO                                     

Name
MAP3K4, MEKK4
Definition
mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
Pathway
ko04010  MAPK signaling pathway
ko04013  MAPK signaling pathway - fly
ko04624  Toll and Imd signaling pathway
ko04912  GnRH signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4
   04013 MAPK signaling pathway - fly
    K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4
 09150 Organismal Systems
  09151 Immune system
   04624 Toll and Imd signaling pathway
    K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4
  09152 Endocrine system
   04912 GnRH signaling pathway
    K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4
Protein kinases [BR:ko01001]
 Serine/threonine kinases: STE group
  STE11 family
   K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4
Other DBs
GO: 0004709
Genes
HSA: 4216(MAP3K4)
PTR: 463119(MAP3K4)
PPS: 100981441(MAP3K4)
GGO: 101152649(MAP3K4)
PON: 100442172(MAP3K4)
NLE: 100602313(MAP3K4)
MCC: 710360(MAP3K4)
MCF: 101865276(MAP3K4)
CSAB: 103240840(MAP3K4)
RRO: 104669999(MAP3K4)
RBB: 108527990(MAP3K4)
CJC: 100413660(MAP3K4)
SBQ: 101042401(MAP3K4)
MMU: 26407(Map3k4)
MCAL: 110312545(Map3k4)
MPAH: 110338018(Map3k4)
RNO: 308106(Map3k4)
MUN: 110554862(Map3k4)
CGE: 100764060(Map3k4)
NGI: 103737023(Map3k4)
HGL: 101701961(Map3k4)
CCAN: 109700149(Map3k4)
OCU: 100358104(MAP3K4)
TUP: 102479582(MAP3K4)
CFA: 476262(MAP3K4)
VVP: 112932971(MAP3K4)
AML: 100465667(MAP3K4)
UMR: 103660898(MAP3K4)
UAH: 113259629(MAP3K4)
ORO: 101379514(MAP3K4)
ELK: 111158665
FCA: 101097977(MAP3K4)
PTG: 102952700(MAP3K4)
PPAD: 109245401(MAP3K4)
AJU: 106985032(MAP3K4)
BTA: 511779(MAP3K4)
BOM: 102283969(MAP3K4)
BIU: 109563601(MAP3K4)
BBUB: 102412509(MAP3K4)
CHX: 102172543(MAP3K4)
OAS: 101113246(MAP3K4)
SSC: 100154202(MAP3K4)
CFR: 102509815(MAP3K4)
CDK: 105086293(MAP3K4)
BACU: 103006512(MAP3K4)
LVE: 103075844(MAP3K4)
OOR: 101277039(MAP3K4)
DLE: 111168464(MAP3K4)
PCAD: 102977794(MAP3K4)
ECB: 100058153(MAP3K4)
EPZ: 103556184(MAP3K4)
EAI: 106842047(MAP3K4)
MYB: 102262729(MAP3K4)
MYD: 102757393(MAP3K4)
MNA: 107535728(MAP3K4)
HAI: 109394013(MAP3K4)
DRO: 112297294(MAP3K4)
PALE: 102888506(MAP3K4)
RAY: 107514741(MAP3K4)
MJV: 108403112(MAP3K4)
LAV: 100664871(MAP3K4)
TMU: 101342450
MDO: 100032495(MAP3K4)
SHR: 100928208(MAP3K4)
PCW: 110208619(MAP3K4)
OAA: 100081562(MAP3K4)
GGA: 421579(MAP3K4)
MGP: 100548383(MAP3K4)
CJO: 107311515(MAP3K4)
NMEL: 110395417(MAP3K4)
APLA: 101795899(MAP3K4)
ACYG: 106039514(MAP3K4)
TGU: 100229845(MAP3K4)
LSR: 110477918(MAP3K4)
SCAN: 103821627(MAP3K4)
GFR: 102043718(MAP3K4)
FAB: 101814940(MAP3K4)
PHI: 102101107(MAP3K4)
PMAJ: 107201928(MAP3K4)
CCAE: 111926951(MAP3K4)
CCW: 104684463(MAP3K4)
ETL: 114055651(MAP3K4)
FPG: 101918017(MAP3K4)
FCH: 102048037(MAP3K4)
CLV: 102086486(MAP3K4)
EGZ: 104124823(MAP3K4)
NNI: 104018435(MAP3K4)
ACUN: 113477881(MAP3K4)
PADL: 103914152(MAP3K4)
AAM: 106486799(MAP3K4)
ASN: 102382136(MAP3K4)
AMJ: 102573918(MAP3K4)
PSS: 102446659(MAP3K4)
CMY: 102936228(MAP3K4)
CPIC: 101946795(MAP3K4)
ACS: 100560027(map3k4)
PVT: 110087352(MAP3K4)
PBI: 103059578(MAP3K4)
PMUR: 107292071(MAP3K4)
TSR: 106549188(MAP3K4)
PMUA: 114594310(MAP3K4)
GJA: 107113333(MAP3K4)
XLA: 100126613(map3k4.S)
XTR: 100497217(map3k4)
NPR: 108795048(MAP3K4)
DRE: 325488(map3k4)
SGH: 107553172 107602945(map3k4)
IPU: 108260840(map3k4)
PHYP: 113544293(map3k4)
AMEX: 103046281(map3k4)
EEE: 113581424(map3k4)
LCO: 104940016(map3k4)
NCC: 104953033(map3k4)
MZE: 101485830(map3k4)
ONL: 100701169(map3k4)
OLA: 101174856(map3k4)
XMA: 102230475(map3k4)
XCO: 114137786(map3k4)
PRET: 103477032(map3k4)
CVG: 107103016(map3k4)
NFU: 107373664(map3k4)
KMR: 108234108(map3k4)
ALIM: 106518124(map3k4)
AOCE: 111562975(map3k4)
CSEM: 103387276(map3k4)
POV: 109634498(map3k4)
LCF: 108894538(map3k4)
SDU: 111234458(map3k4)
SLAL: 111658959(map3k4)
HCQ: 109516250(map3k4)
BPEC: 110157029(map3k4)
MALB: 109961895(map3k4)
ELS: 105008100(map3k4)
SFM: 108942741(map3k4)
PKI: 111853413(map3k4)
LCM: 102366133(MAP3K4)
CMK: 103175928(map3k4)
RTP: 109926885(map3k4)
CIN: 778975
SPU: 592876
APLC: 110978862
DME: Dmel_CG7717(Mekk1)
DER: 6553864
DSE: 6613723
DSI: Dsimw501_GD20154(Dsim_GD20154)
DAN: 6500649
DSR: 110186557
DPE: 6588314
DMN: 108156359
DWI: 6650423
DAZ: 108620887
DNV: 108659620
DHE: 111602613
DVI: 6634984
MDE: 101888375
LCQ: 111681513
AAG: 5573381
AALB: 109430716
AME: 409125
BIM: 100746363
BTER: 100650064
CCAL: 108625647
OBB: 114879059
SOC: 105197492
MPHA: 105831896
AEC: 105143118
ACEP: 105623324
PBAR: 105427085
VEM: 105569890
HST: 105190825
DQU: 106741914
CFO: 105252125
LHU: 105671571
PGC: 109853389
OBO: 105279741
PCF: 106786486
MDL: 103580841
TCA: 663503
DPA: 109542479
ATD: 109600009
NVL: 108565768
BMOR: 101743223
BMAN: 114240977
PRAP: 111001775
HAW: 110378274
TNL: 113493354
PXY: 105387876
API: 100165908
DNX: 107163878
AGS: 114121966
RMD: 113551977
BTAB: 109036367
CLEC: 106674197
ZNE: 110838032
PVM: 113822618
CEL: CELE_B0414.7(mtk-1)
CBR: CBG04061(Cbr-mtk-1)
BMY: Bm1_52175
PCAN: 112565561
MYI: 110456425
LAK: 106171976
EPA: 110234581
ADF: 107350483
AMIL: 114968329
PDAM: 113678862
SPIS: 111322508
DGT: 114534159
AQU: 100634854
 » show all
Reference
PMID:9079650
  Authors
Gerwins P, Blank JL, Johnson GL
  Title
Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway.
  Journal
J Biol Chem 272:8288-95 (1997)
DOI:10.1074/jbc.272.13.8288
  Sequence
[mmu:26407]

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