KEGG   ORTHOLOGY: K04431Help
Entry
K04431                      KO                                     

Name
MAP2K7, MKK7
Definition
mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
Pathway
ko04010  MAPK signaling pathway
ko04012  ErbB signaling pathway
ko04013  MAPK signaling pathway - fly
ko04141  Protein processing in endoplasmic reticulum
ko04214  Apoptosis - fly
ko04380  Osteoclast differentiation
ko04530  Tight junction
ko04620  Toll-like receptor signaling pathway
ko04624  Toll and Imd signaling pathway
ko04660  T cell receptor signaling pathway
ko04664  Fc epsilon RI signaling pathway
ko04668  TNF signaling pathway
ko04722  Neurotrophin signaling pathway
ko04912  GnRH signaling pathway
ko04926  Relaxin signaling pathway
ko05164  Influenza A
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05418  Fluid shear stress and atherosclerosis
Module
M00688  MAPK (JNK) signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04013 MAPK signaling pathway - fly
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04012 ErbB signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04668 TNF signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
 09140 Cellular Processes
  09143 Cell growth and death
   04214 Apoptosis - fly
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  09144 Cellular community - eukaryotes
   04530 Tight junction
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04624 Toll and Imd signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04660 T cell receptor signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04664 Fc epsilon RI signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  09152 Endocrine system
   04912 GnRH signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   04926 Relaxin signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  09158 Development
   04380 Osteoclast differentiation
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
 09160 Human Diseases
  09165 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
  09167 Infectious diseases
   05164 Influenza A
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
   05169 Epstein-Barr virus infection
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00688  MAPK (JNK) signaling
     K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
Protein kinases [BR:ko01001]
 Serine/threonine kinases: STE group
  STE7 family
   K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7
BRITE hierarchy
Other DBs
GO: 0004708
Genes
HSA: 5609(MAP2K7)
PTR: 743199(MAP2K7)
PPS: 100989537(MAP2K7)
GGO: 101124339(MAP2K7)
PON: 100431600(MAP2K7)
NLE: 100587140(MAP2K7)
MCC: 710077(MAP2K7)
MCF: 102126975(MAP2K7)
CSAB: 103233823(MAP2K7)
RRO: 104679497(MAP2K7)
RBB: 108534524(MAP2K7)
CJC: 100412930(MAP2K7)
SBQ: 101047840(MAP2K7)
MMU: 26400(Map2k7)
RNO: 363855(Map2k7)
CGE: 100754421(Map2k7)
NGI: 103726522(Map2k7)
HGL: 101710666(Map2k7)
CCAN: 109698434(Map2k7)
OCU: 103345313(MAP2K7)
TUP: 102500732(MAP2K7)
CFA: 485004(MAP2K7)
AML: 100475975(MAP2K7)
UMR: 103681888(MAP2K7)
ORO: 101382078(MAP2K7)
FCA: 101095157(MAP2K7)
PTG: 102949140(MAP2K7)
AJU: 106970785(MAP2K7)
BTA: 787278(MAP2K7)
BOM: 102272638(MAP2K7)
BIU: 109560948(MAP2K7)
PHD: 102327200(MAP2K7)
CHX: 102173178(MAP2K7)
OAS: 100302082(MAP2K7)
SSC: 100520418(MAP2K7)
CFR: 102506459(MAP2K7)
CDK: 105087572(MAP2K7)
BACU: 103011683(MAP2K7)
LVE: 103091499(MAP2K7)
OOR: 101288079(MAP2K7)
ECB: 100147230(MAP2K7)
EPZ: 103543808(MAP2K7)
EAI: 106844503(MAP2K7)
MYB: 102247950(MAP2K7)
MYD: 102760954(MAP2K7)
HAI: 109396087(MAP2K7)
RSS: 109434721(MAP2K7)
PALE: 102892533(MAP2K7)
LAV: 100673238(MAP2K7)
TMU: 101346746
MDO: 100026752(MAP2K7)
SHR: 100926110(MAP2K7)
OAA: 100089737(MAP2K7)
GGA: 107050551
CJO: 107307804
APLA: 101794019(MAP2K7)
GFR: 102038813(MAP2K7)
PHI: 102100701(MAP2K7)
PMAJ: 107198843(MAP2K7)
FPG: 101924219(MAP2K7)
FCH: 102048069(MAP2K7)
EGZ: 104129979(MAP2K7)
ASN: 102372350(MAP2K7)
AMJ: 102562496(MAP2K7)
PSS: 102463924(MAP2K7)
CMY: 102932325(MAP2K7)
CPIC: 101931768(MAP2K7)
ACS: 100566152(map2k7)
PVT: 110082669(MAP2K7)
PBI: 103066234(MAP2K7)
GJA: 107117671(MAP2K7)
XLA: 108712658 394391(map2k7.S)
XTR: 613115(map2k7)
NPR: 108790540(MAP2K7)
DRE: 560913(map2k7)
SGH: 107567797(map2k7) 107602992
IPU: 108258614(map2k7)
AMEX: 103024363(map2k7)
TRU: 101064650(map2k7)
LCO: 104934939(map2k7)
NCC: 104951572(map2k7)
MZE: 101475777(map2k7)
OLA: 101164950(map2k7)
XMA: 102238025(map2k7)
PRET: 103467648(map2k7)
NFU: 107382265(map2k7)
CSEM: 103383563(map2k7)
LCF: 108875834(map2k7)
HCQ: 109511101(map2k7)
BPEC: 110166191(map2k7)
ELS: 105021508(map2k7)
SFM: 108939797(map2k7)
LCM: 102365163(MAP2K7)
CMK: 103173024(map2k7)
CIN: 778674(mapkk7)
SPU: 591137
APLC: 110986882
SKO: 100376238
DME: Dmel_CG4353(hep)
DSI: Dsimw501_GD15909(Dsim_GD15909)
MDE: 101892997
AAG: 5578019
AME: 413389(hem)
BIM: 100740833
BTER: 100631092
SOC: 105195984
AEC: 105151228
ACEP: 105619941
PBAR: 105424720
HST: 105185444
CFO: 105252678
LHU: 105675778
PGC: 109857214
NVI: 100121060
TCA: 103315236(hep)
DPA: 109543217
NVL: 108566466
BMOR: 100862753
PMAC: 106711754
PRAP: 111002093
API: 100165019
DNX: 107167783
ZNE: 110838369
FCD: 110847803
TUT: 107371332
CEL: CELE_K08A8.1(mek-1)
CBR: CBG16698(Cbr-mek-1)
BMY: Bm1_27865
CRG: 105339236
MYI: 110464981
OBI: 106868012
EPA: 110244754
ADF: 107332902
HMG: 100201328
AQU: 100640493
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9372971
  Authors
Wu Z, Wu J, Jacinto E, Karin M
  Title
Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinase.
  Journal
Mol Cell Biol 17:7407-16 (1997)
DOI:10.1128/MCB.17.12.7407
  Sequence
[hsa:5609]

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