KEGG   ORTHOLOGY: K04437Help
Entry
K04437                      KO                                     

Name
FLNA
Definition
filamin
Pathway
ko04010  MAPK signaling pathway
ko04510  Focal adhesion
ko05132  Salmonella infection
ko05205  Proteoglycans in cancer
Disease
H00270  Periventricular nodular heterotopia (PVNH)
H00456  Fronto-otopalatodigital syndromes
H00461  FLNB-related disorders
H00499  Spondylocarpotarsal synostosis syndrome
H00594  Distal myopathy
H00595  Myofibrillar myopathies (MFM)
H00894  FG syndrome (FGS)
H01276  Chronic idiopathic intestinal pseudo-obstruction
H01740  Macrothrombocytopenia
H01868  Mitral valve prolapse
H02048  Larsen syndrome
H02064  Atelosteogenesis
H02067  Boomerang dysplasia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04437  FLNA; filamin
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K04437  FLNA; filamin
 09160 Human Diseases
  09161 Cancers
   05205 Proteoglycans in cancer
    K04437  FLNA; filamin
  09167 Infectious diseases
   05132 Salmonella infection
    K04437  FLNA; filamin
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K04437  FLNA; filamin
   04147 Exosome
    K04437  FLNA; filamin
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     K04437  FLNA; filamin
  Intermediate filaments
   Intermediate filament-binding proteins
    K04437  FLNA; filamin
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K04437  FLNA; filamin
BRITE hierarchy
Genes
HSA: 2316(FLNA) 2317(FLNB) 2318(FLNC)
PTR: 460476(FLNB) 463711(FLNC) 465940(FLNA)
PPS: 100980320(FLNA) 100991254(FLNC) 100992733(FLNB)
GGO: 101130344(FLNB) 101134853(FLNA) 101142657(FLNC) 101144974
PON: 100436976(FLNB) 100446579(FLNA) 100447210(FLNC)
NLE: 100584689(FLNC) 100585343 100597513(FLNA) 100603369(FLNB)
MCC: 699524(FLNA) 700223(FLNC) 702732(FLNB)
MCF: 102114837(FLNC) 102134285(FLNB) 102138509(FLNA)
CSAB: 103226867(FLNC) 103227804(FLNB) 103232822(FLNA)
RRO: 104660189(FLNB) 104663540(FLNA) 104674436(FLNC) 104674440
CJC: 100385221(FLNA) 100394911(FLNB) 100397531(FLNC) 103790788
SBQ: 101030782(FLNC) 101033199(FLNB) 101038946(FLNA)
MMU: 192176(Flna) 286940(Flnb) 68794(Flnc)
RNO: 293860(Flna) 306204(Flnb) 362332(Flnc)
CGE: 100751994(Flnc) 100760050(Flna) 100769967(Flnb)
HGL: 101702004(Flna) 101714131(Flnb) 101714775(Flnc)
OCU: 100008760(FLNB) 100328754(FLNA) 100328756(RA_M006_JSM7BED4F) 100353671(FLNC)
TUP: 102493536(FLNA) 102497970(FLNB) 102498440(FLNC)
CFA: 481084(FLNA) 482266(FLNC) 484713(FLNB)
AML: 100467791 100475857(FLNC) 100481308(FLNB)
UMR: 103674200(FLNB) 103676641(FLNC) 103679686(FLNA)
ORO: 101380560(FLNA) 101382948(FLNB) 101383660(FLNC)
FCA: 101081210(FLNC) 101082637(FLNA) 101098612(FLNB)
PTG: 102951673(FLNB) 102958609(FLNC) 102969406(FLNA)
AJU: 106968844(FLNB) 106973900(FLNC) 106989714
BTA: 281165(FLNA) 528415(FLNC) 613533(FLNB)
BOM: 102265714(FLNB) 102281567(FLNA) 102287936(FLNC)
BIU: 109555118(FLNA) 109557606(FLNC) 109576011(FLNB)
PHD: 102321668(FLNB) 102327369(FLNA) 102329018(FLNC)
CHX: 102170485(FLNC) 102176601(FLNA) 102187630(FLNB)
OAS: 101104655(FLNC) 101120390(FLNA) 101123330(FLNB) 105605699
SSC: 100514491(FLNB) 100518997(FLNC) 733585(FLNA)
CDK: 105085371(FLNC) 105089800(FLNB) 105098720(FLNA)
BACU: 103000025(FLNA) 103001285(FLNC) 103018177(FLNB)
LVE: 103070633(FLNA) 103082555(FLNB) 103085481(FLNC)
OOR: 101275748(FLNA) 101277589(FLNC) 101285072(FLNB)
ECB: 100057963(FLNB) 100058256(FLNA) 100071760(FLNC)
EAI: 106825616(FLNA) 106839532(FLNC) 106848649(FLNB)
MYB: 102246018(FLNC) 102255293(FLNB) 102257802(FLNA)
MYD: 102756703(FLNC) 102761579(FLNB) 102764268(FLNA)
HAI: 109377338(FLNA) 109384635(FLNC) 109388247(FLNB)
RSS: 109443598(FLNB) 109457223(FLNC) 109460079(FLNA)
PALE: 102887099(FLNB) 102889996(FLNA) 102894137(FLNC)
LAV: 100655159(FLNB) 100666153(FLNC) 100674763(FLNA)
MDO: 100014156(FLNB) 100014995(FLNC) 100617907(FLNA)
SHR: 100923582(FLNB) 100924343(FLNA) 100932639(FLNC)
OAA: 100077046(FLNA) 100078338(FLNC) 100084462(FLNB)
GGA: 378913(FLNB) 395260(FLNC) 395261(FLNA)
MGP: 100549125(FLNB)
APLA: 101796074 101797258(FLNB)
ACYG: 106037975(FLNB) 106048920(FLNC)
TGU: 100224625(FLNC) 100230709(FLNB)
FAB: 101807613(FLNC) 101815478(FLNB)
PHI: 102102293(FLNA) 102109930(FLNC) 102113738(FLNB)
PMAJ: 107198769(FLNC) 107210334(FLNB)
CCW: 104683467(FLNB)
FPG: 101914782(FLNB) 101921248(FLNC)
FCH: 102048385(FLNC) 102055640(FLNB)
EGZ: 104126644(FLNB)
ASN: 102367807(FLNC) 102368306(FLNB) 102370975(FLNA)
AMJ: 102570042(FLNB) 102572603(FLNC) 102573539(FLNA)
PSS: 102454001(FLNB) 102459888
CMY: 102942474(FLNC) 102947590(FLNB)
CPIC: 101935574(FLNA) 101940457 101948714(FLNC) 101953493(FLNB)
PVT: 110078614(FLNA) 110082409(FLNB) 110089402(FLNC)
PBI: 103050411(FLNC) 103063627(FLNA) 103064197(FLNB)
XTR: 100329116(flnc) 100485165(flnb) 779840(flna)
NPR: 108790450(FLNA) 108791862(FLNB) 108794883(FLNC)
DRE: 100048921(flnca) 100534866(flnb) 562529(flna) 563023(flnb) 570288(flncb)
LCO: 104935653 104936022 104936893(Filamin-C) 104940629(Filamin-C)
ELS: 105013504 105013563(flnb) 105021804(flnc)
LCM: 102345455(FLNA) 102352444(FLNC) 102360310(FLNB)
CMK: 103190015(flnc) 103190036(flnb)
CIN: 100186514
SPU: 579510(flnb) 587317(FLNA)
DSI: Dsimw501_GD15083(Dsim_GD15083) Dsimw501_GD20251(Dsim_GD20251) Dsimw501_GD25106(Dsim_GD25106)
AAG: 5572167
AME: 409697(GB13109) 410171 552466(GB14141)
CEL: CELE_C23F12.1(fln-2) CELE_Y66H1B.2(fln-1)
DDI: DDB_G0269100(abpC)
DFA: DFA_01474(abpC)
EHI: EHI_104630(3.t00014)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Adams M, Simms RJ, Abdelhamed Z, Dawe HR, Szymanska K, Logan CV, Wheway G, Pitt E, Gull K, Knowles MA, Blair E, Cross SH, Sayer JA, Johnson CA
  Title
A meckelin-filamin A interaction mediates ciliogenesis.
  Journal
Hum Mol Genet 21:1272-86 (2012)
DOI:10.1093/hmg/ddr557
  Sequence
[hsa:2316] [mmu:192176]

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