KEGG   ORTHOLOGY: K04446Help
Entry
K04446                      KO                                     

Name
NFATC1, NFAT2, NFATC
Definition
nuclear factor of activated T-cells, cytoplasmic 1
Pathway
ko04010  MAPK signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04024  cAMP signaling pathway
ko04218  Cellular senescence
ko04310  Wnt signaling pathway
ko04380  Osteoclast differentiation
ko04625  C-type lectin receptor signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04660  T cell receptor signaling pathway
ko04662  B cell receptor signaling pathway
ko04921  Oxytocin signaling pathway
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko05161  Hepatitis B
ko05163  Human cytomegalovirus infection
ko05166  HTLV-I infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05321  Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
   04310 Wnt signaling pathway
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
   04024 cAMP signaling pathway
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
   04022 cGMP - PKG signaling pathway
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
   04650 Natural killer cell mediated cytotoxicity
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
   04660 T cell receptor signaling pathway
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
   04658 Th1 and Th2 cell differentiation
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
   04659 Th17 cell differentiation
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
   04662 B cell receptor signaling pathway
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
  09158 Development
   04380 Osteoclast differentiation
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
 09160 Human Diseases
  09162 Immune diseases
   05321 Inflammatiory bowel disease (IBD)
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
  09166 Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
  09167 Infectious diseases
   05166 HTLV-I infection
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
   05161 Hepatitis B
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
   05163 Human cytomegalovirus infection
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
Transcription factors [BR:ko03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) NF-AT
    K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
BRITE hierarchy
Genes
HSA: 4772(NFATC1)
PTR: 455485(NFATC1)
PPS: 100974281(NFATC1)
GGO: 101147593(NFATC1)
PON: 100436209(NFATC1)
NLE: 100598995(NFATC1)
MCC: 698089(NFATC1)
MCF: 102133233(NFATC1)
CSAB: 103244028(NFATC1)
RRO: 104667797(NFATC1)
RBB: 108525049(NFATC1)
CJC: 100405187(NFATC1)
MMU: 18018(Nfatc1)
RNO: 100361818(Nfatc1)
CGE: 100764851(Nfatc1)
NGI: 103748128(Nfatc1)
HGL: 101697946(Nfatc1)
CCAN: 109686431(Nfatc1)
OCU: 100352378(NFATC1)
TUP: 102481120(NFATC1)
CFA: 483925(NFATC1)
AML: 100470861(NFATC1)
UMR: 103658473(NFATC1)
ORO: 101385449(NFATC1)
FCA: 101101259(NFATC1)
AJU: 106977679(NFATC1)
BTA: 511224(NFATC1)
BIU: 109577750(NFATC1)
PHD: 102315366(NFATC1)
CHX: 102188180(NFATC1)
OAS: 101108097(NFATC1)
SSC: 397318(NFATC1)
CFR: 102523589(NFATC1)
CDK: 105103850(NFATC1)
BACU: 102999338(NFATC1)
LVE: 103081110(NFATC1)
OOR: 101283533(NFATC1)
ECB: 100065378(NFATC1)
EAI: 106834926(NFATC1)
MYB: 102245976(NFATC1)
MYD: 102763205(NFATC1)
HAI: 109383198(NFATC1)
RSS: 109436828(NFATC1)
PALE: 102880857(NFATC1)
LAV: 100655623(NFATC1)
TMU: 101359059
MDO: 100023153(NFATC1)
SHR: 100926364(NFATC1)
OAA: 100078396(NFATC1)
GGA: 420815(NFATC1)
MGP: 100545778(NFATC1)
CJO: 107309755(NFATC1)
APLA: 101793899(NFATC1)
ACYG: 106038339(NFATC1)
TGU: 100225123(NFATC1)
GFR: 102038895(NFATC1)
FAB: 101811894(NFATC1)
PHI: 102114296(NFATC1)
PMAJ: 107200735(NFATC1)
CCW: 104688858(NFATC1)
FPG: 101913726(NFATC1)
FCH: 102046809(NFATC1)
CLV: 102091094(NFATC1)
EGZ: 104125444(NFATC1)
AAM: 106500234(NFATC1)
ASN: 102368918 102386486(NFATC1)
AMJ: 102559296(NFATC1)
PSS: 102452242(NFATC1)
CMY: 102929542(NFATC1)
CPIC: 101932823(NFATC1)
ACS: 100565300(nfatc1)
PVT: 110072900(NFATC1)
PBI: 103053062(NFATC1)
GJA: 107111515(NFATC1)
XLA: 108695211(nfatc1.S) 444346(nfatc1.L)
XTR: 780197(nfatc1)
NPR: 108784253(NFATC1)
DRE: 568315(nfatc1) 571865
SRX: 107739553 107748694(nfatc1)
IPU: 108257496(nfatc1) 108280571(NFATC1)
AMEX: 103031085(nfatc1) 103045210
OLA: 101158005(nfatc1) 101161493
NFU: 107378925(nfatc1) 107394905
LCF: 108887849(nfatc1) 108899182
CMK: 103183227(nfatc1)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8202141
  Authors
Northrop JP, Ho SN, Chen L, Thomas DJ, Timmerman LA, Nolan GP, Admon A, Crabtree GR
  Title
NF-AT components define a family of transcription factors targeted in T-cell activation.
  Journal
Nature 369:497-502 (1994)
DOI:10.1038/369497a0
  Sequence
[hsa:4772]

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