KEGG   ORTHOLOGY: K04448Help
Entry
K04448                      KO                                     

Name
JUN
Definition
transcription factor AP-1
Pathway
ko01522  Endocrine resistance
ko04010  MAPK signaling pathway
ko04012  ErbB signaling pathway
ko04013  MAPK signaling pathway - fly
ko04024  cAMP signaling pathway
ko04137  Mitophagy - animal
ko04210  Apoptosis
ko04214  Apoptosis - fly
ko04310  Wnt signaling pathway
ko04380  Osteoclast differentiation
ko04510  Focal adhesion
ko04530  Tight junction
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04624  Toll and Imd signaling pathway
ko04625  C-type lectin receptor signaling pathway
ko04657  IL-17 signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04660  T cell receptor signaling pathway
ko04662  B cell receptor signaling pathway
ko04668  TNF signaling pathway
ko04722  Neurotrophin signaling pathway
ko04912  GnRH signaling pathway
ko04915  Estrogen signaling pathway
ko04921  Oxytocin signaling pathway
ko04926  Relaxin signaling pathway
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko05030  Cocaine addiction
ko05031  Amphetamine addiction
ko05120  Epithelial cell signaling in Helicobacter pylori infection
ko05132  Salmonella infection
ko05133  Pertussis
ko05140  Leishmaniasis
ko05142  Chagas disease (American trypanosomiasis)
ko05161  Hepatitis B
ko05164  Influenza A
ko05166  Human T-cell leukemia virus 1 infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05200  Pathways in cancer
ko05203  Viral carcinogenesis
ko05210  Colorectal cancer
ko05211  Renal cell carcinoma
ko05224  Breast cancer
ko05231  Choline metabolism in cancer
ko05321  Inflammatory bowel disease (IBD)
ko05323  Rheumatoid arthritis
ko05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04448  JUN; transcription factor AP-1
   04013 MAPK signaling pathway - fly
    K04448  JUN; transcription factor AP-1
   04012 ErbB signaling pathway
    K04448  JUN; transcription factor AP-1
   04310 Wnt signaling pathway
    K04448  JUN; transcription factor AP-1
   04668 TNF signaling pathway
    K04448  JUN; transcription factor AP-1
   04024 cAMP signaling pathway
    K04448  JUN; transcription factor AP-1
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    K04448  JUN; transcription factor AP-1
  09143 Cell growth and death
   04210 Apoptosis
    K04448  JUN; transcription factor AP-1
   04214 Apoptosis - fly
    K04448  JUN; transcription factor AP-1
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K04448  JUN; transcription factor AP-1
   04530 Tight junction
    K04448  JUN; transcription factor AP-1
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K04448  JUN; transcription factor AP-1
   04624 Toll and Imd signaling pathway
    K04448  JUN; transcription factor AP-1
   04621 NOD-like receptor signaling pathway
    K04448  JUN; transcription factor AP-1
   04625 C-type lectin receptor signaling pathway
    K04448  JUN; transcription factor AP-1
   04660 T cell receptor signaling pathway
    K04448  JUN; transcription factor AP-1
   04658 Th1 and Th2 cell differentiation
    K04448  JUN; transcription factor AP-1
   04659 Th17 cell differentiation
    K04448  JUN; transcription factor AP-1
   04657 IL-17 signaling pathway
    K04448  JUN; transcription factor AP-1
   04662 B cell receptor signaling pathway
    K04448  JUN; transcription factor AP-1
  09152 Endocrine system
   04912 GnRH signaling pathway
    K04448  JUN; transcription factor AP-1
   04915 Estrogen signaling pathway
    K04448  JUN; transcription factor AP-1
   04921 Oxytocin signaling pathway
    K04448  JUN; transcription factor AP-1
   04926 Relaxin signaling pathway
    K04448  JUN; transcription factor AP-1
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K04448  JUN; transcription factor AP-1
  09158 Development
   04380 Osteoclast differentiation
    K04448  JUN; transcription factor AP-1
 09160 Human Diseases
  09161 Cancers
   05200 Pathways in cancer
    K04448  JUN; transcription factor AP-1
   05231 Choline metabolism in cancer
    K04448  JUN; transcription factor AP-1
   05203 Viral carcinogenesis
    K04448  JUN; transcription factor AP-1
   05210 Colorectal cancer
    K04448  JUN; transcription factor AP-1
   05211 Renal cell carcinoma
    K04448  JUN; transcription factor AP-1
   05224 Breast cancer
    K04448  JUN; transcription factor AP-1
  09162 Immune diseases
   05323 Rheumatoid arthritis
    K04448  JUN; transcription factor AP-1
   05321 Inflammatiory bowel disease (IBD)
    K04448  JUN; transcription factor AP-1
  09164 Substance dependence
   05030 Cocaine addiction
    K04448  JUN; transcription factor AP-1
   05031 Amphetamine addiction
    K04448  JUN; transcription factor AP-1
  09165 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K04448  JUN; transcription factor AP-1
  09166 Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04448  JUN; transcription factor AP-1
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04448  JUN; transcription factor AP-1
  09167 Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04448  JUN; transcription factor AP-1
   05132 Salmonella infection
    K04448  JUN; transcription factor AP-1
   05133 Pertussis
    K04448  JUN; transcription factor AP-1
   05166 HTLV-I infection
    K04448  JUN; transcription factor AP-1
   05164 Influenza A
    K04448  JUN; transcription factor AP-1
   05161 Hepatitis B
    K04448  JUN; transcription factor AP-1
   05168 Herpes simplex infection
    K04448  JUN; transcription factor AP-1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04448  JUN; transcription factor AP-1
   05169 Epstein-Barr virus infection
    K04448  JUN; transcription factor AP-1
   05140 Leishmaniasis
    K04448  JUN; transcription factor AP-1
   05142 Chagas disease (American trypanosomiasis)
    K04448  JUN; transcription factor AP-1
  09168 Drug resistance
   01522 Endocrine resistance
    K04448  JUN; transcription factor AP-1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04448  JUN; transcription factor AP-1
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Jun
    K04448  JUN; transcription factor AP-1
BRITE hierarchy
Genes
HSA: 3725(JUN)
PTR: 456893(JUN)
PPS: 100980908(JUN)
GGO: 101145729(JUN)
PON: 100450292(JUN)
NLE: 100586501(JUN)
MCC: 716452(JUN)
MCF: 102126446(JUN)
CSAB: 103224726(JUN)
RRO: 104664278(JUN)
RBB: 108532921(JUN)
CJC: 100400411(JUN)
SBQ: 101043809(JUN)
MMU: 16476(Jun)
RNO: 24516(Jun)
CGE: 100766306(Jun)
NGI: 103737138(Jun)
HGL: 101722197(Jun)
CCAN: 109700777(Jun)
OCU: 100008856(JUN) 100338341(EIF5A)
TUP: 102496870(JUN)
CFA: 609429(JUN)
AML: 100483834(JUN)
UMR: 103670861(JUN)
ORO: 101368207(JUN)
FCA: 101097261(JUN)
PTG: 102958666(JUN)
AJU: 106974986(JUN)
BTA: 280831(JUN)
BOM: 102267895(JUN)
BIU: 109556235(JUN)
PHD: 102339068(JUN)
CHX: 102185423(JUN)
OAS: 443219(JUN)
SSC: 396913(JUN)
CFR: 102516943
CDK: 105092850(JUN)
LVE: 103071861(JUN)
OOR: 101288913(JUN)
ECB: 100067469(JUN)
EAI: 106833477(JUN)
MYB: 102260808(JUN)
MYD: 102752693(JUN)
HAI: 109371251(JUN) 109371257
RSS: 109453068(JUN)
PALE: 102896121(JUN)
LAV: 100670432(JUN)
TMU: 101361653
MDO: 100018774(JUN)
GGA: 424673(JUN)
MGP: 100548501(JUN)
CJO: 107317693(JUN)
APLA: 101796626(JUN)
ACYG: 106032923(JUN)
TGU: 100229914(JUN)
GFR: 102039078(JUN)
FAB: 101816255(JUN)
PHI: 102112236(JUN)
PMAJ: 107208073(JUN)
CCW: 104695158(JUN)
FPG: 101918818(JUN)
FCH: 102050406(JUN)
CLV: 102092209(JUN)
EGZ: 104123944(JUN)
AAM: 106494500(JUN)
ASN: 102374896(JUN)
AMJ: 102566064(JUN)
PSS: 102455008(JUN)
CMY: 102937264(JUN)
CPIC: 101930786(JUN) 103306405
ACS: 100567718(jun)
PVT: 110077124(JUN)
PBI: 103057921(JUN) 103061257
GJA: 107111867(JUN)
XLA: 108700666 379050(jun.S) 399400(jun.L)
XTR: 100493911(jun)
NPR: 108788164(JUN)
DRE: 335916(jun)
IPU: 108258130(jun) 108260086 108267848(JUN)
AMEX: 103021920 103026868(jun)
TRU: 101064806(jun) 101077059(c-jun)
XMA: 102230050(jun) 102234665
PRET: 103463760 103478989(jun)
NFU: 107384375(jun) 107396464
CSEM: 103376719(jun) 103398819
BPEC: 110154702(jun) 110173458
SFM: 108923530 108935116(jun)
LCM: 102350279(JUN) 102358101
CMK: 103185297(jun) 103187587
CIN: 778972(jun)
SPU: 588294
APLC: 110977802
SKO: 100313553
DME: Dmel_CG2275(Jra)
DSI: Dsimw501_GD15385(Dsim_GD15385)
MDE: 101896731
AAG: 5578266
AME: 726289(Jra)
BIM: 100750048
BTER: 100645950
SOC: 105200133
AEC: 105155106
ACEP: 105621323
PBAR: 105428867
HST: 105190515
CFO: 105253340
LHU: 105671646
PGC: 109856529
NVI: 100123087
TCA: 663937(Jra)
DPA: 109542182
NVL: 108557779
BMOR: 101736835
PMAC: 106715838
PRAP: 110996297
PXY: 105388607
DNX: 107166782
ZNE: 110827968
FCD: 110859845
TUT: 107364868
BMY: Bm1_43340
CRG: 105341654
OBI: 106868153
LAK: 106165046
HMG: 100204820(jun)
AQU: 100640297
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Liu J, Han Q, Peng T, Peng M, Wei B, Li D, Wang X, Yu S, Yang J, Cao S, Huang K, Hutchins AP, Liu H, Kuang J, Zhou Z, Chen J, Wu H, Guo L, Chen Y, Chen Y, Li X, Wu H, Liao B, He W, Song H, Yao H, Pan G, Chen J, Pei D
  Title
The oncogene c-Jun impedes somatic cell reprogramming.
  Journal
Nat Cell Biol 17:856-67 (2015)
DOI:10.1038/ncb3193
Reference
PMID:3194415
  Authors
Hattori K, Angel P, Le Beau MM, Karin M
  Title
Structure and chromosomal localization of the functional intronless human JUN protooncogene.
  Journal
Proc Natl Acad Sci U S A 85:9148-52 (1988)
DOI:10.1073/pnas.85.23.9148
  Sequence
[hsa:3725]

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