KEGG   ORTHOLOGY: K04452Help
Entry
K04452                      KO                                     

Name
DDIT3, GADD153
Definition
DNA damage-inducible transcript 3
Pathway
ko04010  MAPK signaling pathway
ko04141  Protein processing in endoplasmic reticulum
ko04210  Apoptosis
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko05202  Transcriptional misregulation in cancer
Disease
H00049  Myxoid liposarcoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
 09160 Human Diseases
  09161 Cancers
   05202 Transcriptional misregulation in cancers
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
  09166 Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Basic leucine zipper (bZIP)
   C/EBP-like factors
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
BRITE hierarchy
Genes
HSA: 1649(DDIT3)
PTR: 452017(DDIT3)
PPS: 100982590(DDIT3)
GGO: 101140706(DDIT3)
PON: 100439399(DDIT3)
NLE: 100600067(DDIT3)
MCC: 714901(DDIT3)
MCF: 102131632(DDIT3)
CSAB: 103238566(DDIT3)
RRO: 104682361(DDIT3)
RBB: 108519685(DDIT3)
CJC: 100385367(DDIT3) 103794361
SBQ: 104651132(DDIT3)
MMU: 13198(Ddit3)
RNO: 29467(Ddit3)
CGE: 100763514(Ddit3)
NGI: 103742913(Ddit3)
HGL: 101715873(Ddit3)
CCAN: 109675714 109686362(Ddit3)
OCU: 100338439(DDIT3)
TUP: 102500216(DDIT3)
CFA: 607439(DDIT3)
AML: 100479063(DDIT3)
UMR: 103656598(DDIT3)
ORO: 101380889(DDIT3)
FCA: 101081819(DDIT3)
PTG: 102965918(DDIT3)
AJU: 106975861(DDIT3)
BTA: 777788(DDIT3)
BOM: 102284065(DDIT3)
BIU: 109559326(DDIT3)
PHD: 102322887(DDIT3)
CHX: 102175557(DDIT3)
OAS: 541600(DDIT3)
SSC: 100240743(DDIT3)
CFR: 102517621(DDIT3)
CDK: 105100346(DDIT3)
BACU: 103018481(DDIT3)
LVE: 103069139(DDIT3)
OOR: 101278090(DDIT3)
ECB: 100053417(DDIT3)
EPZ: 103559784(DDIT3)
EAI: 106833003(DDIT3)
MYB: 102255226(DDIT3)
MYD: 102764039(DDIT3)
HAI: 109390744(DDIT3)
RSS: 109452935(DDIT3)
PALE: 102890557(DDIT3)
LAV: 100660941(DDIT3)
TMU: 101361189
SHR: 100931338(DDIT3)
OAA: 103167225(DDIT3)
GGA: 100857832(DDIT3)
APLA: 101802390(DDIT3)
ACYG: 106049589(DDIT3)
PMAJ: 107199033(DDIT3)
ASN: 102384643(DDIT3)
AMJ: 102574043(DDIT3)
PSS: 102448363(DDIT3)
CMY: 102934528(DDIT3)
CPIC: 101947222(DDIT3)
ACS: 100567470(ddit3)
PVT: 110070828(DDIT3)
PBI: 103050195(DDIT3)
GJA: 107118957(DDIT3)
XLA: 108709861(ddit3.S) 398615(ddit3.L)
XTR: 733816(ddit3)
NPR: 108797835(DDIT3)
SRX: 107734605(ddit3)
SANH: 107683613(ddit3)
SGH: 107566410(ddit3)
IPU: 108271880(ddit3)
AMEX: 103022996(ddit3)
LCM: 102361121(DDIT3)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Oyadomari S, Mori M
  Title
Roles of CHOP/GADD153 in endoplasmic reticulum stress.
  Journal
Cell Death Differ 11:381-9 (2004)
DOI:10.1038/sj.cdd.4401373
Reference
  Authors
Perez-Mancera PA, Sanchez-Garcia I
  Title
Understanding mesenchymal cancer: the liposarcoma-associated FUS-DDIT3 fusion gene as a model.
  Journal
Semin Cancer Biol 15:206-14 (2005)
DOI:10.1016/j.semcancer.2005.01.006
Reference
  Authors
Yamaguchi H, Wang HG
  Title
CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells.
  Journal
J Biol Chem 279:45495-502 (2004)
DOI:10.1074/jbc.M406933200
  Sequence
[hsa:1649]

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