KEGG   ORTHOLOGY: K04454Help
Entry
K04454                      KO                                     

Name
MEF2C
Definition
MADS-box transcription enhancer factor 2C
Pathway
ko04010  MAPK signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04371  Apelin signaling pathway
ko04921  Oxytocin signaling pathway
ko04928  Parathyroid hormone synthesis, secretion and action
ko05202  Transcriptional misregulation in cancer
ko05418  Fluid shear stress and atherosclerosis
Disease
H00773  Autosomal dominant mental retardation
H01223  Mental retardation-stereotypic movements-epilepsy and/or cerebral malformations
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
   04371 Apelin signaling pathway
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
   04022 cGMP - PKG signaling pathway
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
   04928 Parathyroid hormone synthesis, secretion and action
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
 09160 Human Diseases
  09161 Cancers
   05202 Transcriptional misregulation in cancers
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
  09165 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
Transcription factors [BR:ko03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   MADS-box regulators of differentiation, MEF-2
    K04454  MEF2C; MADS-box transcription enhancer factor 2C
BRITE hierarchy
Genes
HSA: 4208(MEF2C)
PTR: 461760(MEF2C)
PPS: 100975251(MEF2C)
GGO: 101139415(MEF2C)
PON: 100174751(MEF2C)
NLE: 100585129(MEF2C)
MCC: 694992(MEF2C)
MCF: 102135088(MEF2C)
CSAB: 103224375(MEF2C)
RRO: 104657758(MEF2C)
RBB: 108541059(MEF2C)
CJC: 100413265(MEF2C)
SBQ: 101029713(MEF2C)
MMU: 17260(Mef2c)
RNO: 499497(Mef2c)
CGE: 100774573(Mef2c)
NGI: 103739124(Mef2c)
HGL: 101716335(Mef2c)
CCAN: 109695254(Mef2c)
OCU: 100345167(MEF2C)
TUP: 102499043(MEF2C)
CFA: 479155(MEF2C)
AML: 100464632(MEF2C)
UMR: 103672150(MEF2C)
ORO: 101370419(MEF2C)
FCA: 101096136(MEF2C)
PTG: 102962519(MEF2C)
AJU: 106968666(MEF2C)
BTA: 512254(MEF2C)
BOM: 102286323(MEF2C)
BIU: 109562320(MEF2C)
PHD: 102315309(MEF2C)
CHX: 102175290(MEF2C)
OAS: 100286738(MEF2C)
SSC: 733590(MEF2C)
CFR: 102507710(MEF2C)
CDK: 105099639(MEF2C)
BACU: 103010647(MEF2C)
LVE: 103077870(MEF2C)
OOR: 101273160(MEF2C)
ECB: 100065153(MEF2C)
EPZ: 103550208(MEF2C)
EAI: 106841211(MEF2C)
MYB: 102248648(MEF2C)
MYD: 102763270(MEF2C)
HAI: 109381982(MEF2C)
RSS: 109448659(MEF2C)
PALE: 102883825(MEF2C)
LAV: 100656767(MEF2C)
TMU: 101346475
MDO: 100013140(MEF2C)
SHR: 100932067(MEF2C)
OAA: 100079500(MEF2C)
GGA: 769007(MEF2C)
MGP: 100549600(MEF2C)
CJO: 107306494(MEF2C)
APLA: 101789482(MEF2C)
ACYG: 106047563(MEF2C)
TGU: 100218659(MEF2C)
GFR: 102041745(MEF2C)
FAB: 101809833(MEF2C)
PHI: 102108298(MEF2C)
PMAJ: 107216154(MEF2C)
CCW: 104685221(MEF2C)
FPG: 101912452(MEF2C)
FCH: 102050180(MEF2C)
CLV: 102090045(MEF2C)
EGZ: 104128384(MEF2C)
ASN: 102379600(MEF2C)
AMJ: 102573957(MEF2C)
PSS: 102460770(MEF2C)
CMY: 102944657(MEF2C)
CPIC: 101945993(MEF2C)
ACS: 100559834(mef2c)
PVT: 110073989(MEF2C)
PBI: 103056615(MEF2C)
GJA: 107116735(MEF2C)
XLA: 108707236(mef2c.S) 444310(mef2c.L)
XTR: 100127198(mef2c)
NPR: 108789272(MEF2C)
DRE: 30575(mef2ca) 798771(mef2cb)
IPU: 108255865(mef2c)
AMEX: 103034712(mef2c) 103034979
TRU: 101069405(mef2c) 101070584
LCO: 104926805(mef2c) 104938666
NCC: 104943849 104955195(mef2c)
MZE: 101471731(mef2c) 101479529
OLA: 101160563(mef2c) 101160992
XMA: 102234229 102235148(mef2c)
PRET: 103470448(mef2c) 103473175
NFU: 107393869(mef2c) 107394719
CSEM: 103389640 103397502(mef2c)
LCF: 108878284(mef2c)
HCQ: 109525101 109530704(mef2c)
BPEC: 110157088(mef2c) 110161619
ELS: 105014655(mef2c) 105015210
SFM: 108930052 108938608(mef2c)
LCM: 102361694(MEF2C)
CMK: 103178364(mef2c) 103181987
CIN: 778677(mef2)
CRG: 105332231
OBI: 106878542
BRP: 103864905
BOE: 106341458
THJ: 104809945
GRA: 105764655
GMX: 100793705
AIP: 107606652
PAVI: 110757198
CMO: 103487027
CMAX: 111493355
CPEP: 111788665
RCU: 8263415
JCU: 105643075
JRE: 109013707
SLY: 104645115
NTO: 104089575
SIND: 105169462
HAN: 110871272
LSV: 111909728
SOE: 110799503
DCT: 110105844
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7679508
  Authors
Leifer D, Krainc D, Yu YT, McDermott J, Breitbart RE, Heng J, Neve RL, Kosofsky B, Nadal-Ginard B, Lipton SA
  Title
MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortex.
  Journal
Proc Natl Acad Sci U S A 90:1546-50 (1993)
DOI:10.1073/pnas.90.4.1546
  Sequence
[hsa:4208]

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