KEGG   ORTHOLOGY: K04457Help
Entry
K04457                      KO                                     

Name
PPM1A, PP2CA
Definition
protein phosphatase 1A [EC:3.1.3.16]
Pathway
ko04010  MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04457  PPM1A, PP2CA; protein phosphatase 1A
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatase and associated proteins
    K04457  PPM1A, PP2CA; protein phosphatase 1A
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     K04457  PPM1A, PP2CA; protein phosphatase 1A
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Mg2+- or Mn2+- dependent protein phosphatases (PPMs)
   PPM1 phosphatases (PP2C)
    K04457  PPM1A, PP2CA; protein phosphatase 1A
BRITE hierarchy
Other DBs
GO: 0004722
Genes
HSA: 5494(PPM1A)
PTR: 452950(PPM1A)
PPS: 100970419(PPM1A)
GGO: 101125419(PPM1A)
PON: 100173950(PPM1A)
NLE: 100582171(PPM1A)
MCC: 702987(PPM1A)
MCF: 102124885(PPM1A)
CSAB: 103229109(PPM1A)
RRO: 104662165(PPM1A)
RBB: 108520163(PPM1A)
CJC: 100405518(PPM1A)
SBQ: 101039878(PPM1A)
MMU: 19042(Ppm1a)
RNO: 24666(Ppm1a)
CGE: 100773654(Ppm1a)
NGI: 103739185(Ppm1a)
HGL: 101720711(Ppm1a)
CCAN: 109691691 109701512(Ppm1a)
OCU: 100009431(PPM1A)
TUP: 102486395(PPM1A)
CFA: 480344(PPM1A)
AML: 100472235(PPM1A)
UMR: 103672639(PPM1A)
ORO: 101367915(PPM1A)
FCA: 101101571(PPM1A)
PTG: 102953651(PPM1A)
AJU: 106974580(PPM1A)
BTA: 281994(PPM1A)
BOM: 102285226(PPM1A)
BIU: 109565218(PPM1A)
PHD: 102334333(PPM1A)
CHX: 102177529(PPM1A) 102179463
OAS: 101103023 101103650(PPM1A)
SSC: 100738389(PPM1A)
CFR: 102511888(PPM1A)
CDK: 105086225(PPM1A)
BACU: 103004855(PPM1A)
LVE: 103087588(PPM1A)
OOR: 101287167(PPM1A)
ECB: 100051348(PPM1A)
EPZ: 103550787(PPM1A)
EAI: 106846073(PPM1A)
MYB: 102248880 102249748(PPM1A)
MYD: 102754169(PPM1A)
HAI: 109383789(PPM1A)
RSS: 109441756 109457688(PPM1A)
PALE: 102894756(PPM1A)
LAV: 100672515(PPM1A)
TMU: 101344929
MDO: 100021641(PPM1A)
SHR: 100918256(PPM1A)
OAA: 100086309(PPM1A)
GGA: 423525(PPM1A)
MGP: 100544655(PPM1A)
CJO: 107315408(PPM1A)
APLA: 101799571(PPM1A)
ACYG: 106037224(PPM1A)
TGU: 100225828(PPM1A)
GFR: 102041842(PPM1A)
FAB: 101807578(PPM1A)
PHI: 102113668(PPM1A)
PMAJ: 107205936(PPM1A)
CCW: 104687344(PPM1A)
FPG: 101917369(PPM1A)
FCH: 102058428(PPM1A)
CLV: 102089447(PPM1A)
EGZ: 104135284(PPM1A)
AAM: 106495234(PPM1A)
ASN: 102367870(PPM1A)
AMJ: 102572447(PPM1A)
PSS: 102460132(PPM1A)
CMY: 102930169 102943068(PPM1A)
CPIC: 101944961(PPM1A) 101950387
ACS: 100558424(ppm1a) 100566337
PVT: 110075671(PPM1N) 110090141(PPM1A)
PBI: 103060451(PPM1A)
GJA: 107119535(PPM1A)
XLA: 108698826 380058(ppm1a.L)
XTR: 548912(ppm1a)
NPR: 108791922(PPM1A)
DRE: 30703(ppm1ab) 30704(ppm1aa) 405817(ppm1na) 564875(ppm1nb)
IPU: 108258036(Ppm1a) 108263088(ppm1a) 108277626 108278433(ppm1n)
TRU: 101070341(ppm1a) 101070520
LCO: 104921586(ppm1a) 104929380
NCC: 104945489 104960373(ppm1a)
NFU: 107380295 107392312(ppm1a)
CSEM: 103376996(ppm1a) 103378055
LCM: 102351446(PPM1A) 102355597
CMK: 103185375(ppm1a)
CIN: 100183363
SHX: MS3_08432
ADF: 107334879
HMG: 100210460
CRB: 17878392
BRP: 103861723
BOE: 106301370
TCC: 18605794
PPER: 18785099
MDM: 103444013
MCHA: 111011524
RCU: 8280823
JCU: 105640960
POP: 7475176
SLY: 101262900
SPEN: 107014612
SOT: 102595551
CANN: 107863092
NSY: 104232627
NTO: 104117047
SIND: 105166753
OEU: 111402920
BVG: 104888214
SOE: 110783141
OSA: 4325851
DOSA: Os01t0552300-01(Os01g0552300)
BDI: 100825920
ATS: 109738730(LOC109738730)
SBI: 8075001
ZMA: 100383955
SITA: 101774086
PDA: 103718990
EGU: 105047603
MUS: 103979681
DCT: 110097041
PPP: 112291490
SMIN: v1.2.039398.t1(symbB.v1.2.039398.t1)
SPAR: SPRG_12746
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Lin X, Duan X, Liang YY, Su Y, Wrighton KH, Long J, Hu M, Davis CM, Wang J, Brunicardi FC, Shi Y, Chen YG, Meng A, Feng XH
  Title
PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling.
  Journal
Cell 125:915-28 (2006)
DOI:10.1016/j.cell.2006.03.044
  Sequence
[hsa:5494]
Reference
  Authors
Sun W, Yu Y, Dotti G, Shen T, Tan X, Savoldo B, Pass AK, Chu M, Zhang D, Lu X, Fu S, Lin X, Yang J
  Title
PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activation.
  Journal
Cell Signal 21:95-102 (2009)
DOI:10.1016/j.cellsig.2008.09.012
  Sequence
[hsa:5494]

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