KEGG   ORTHOLOGY: K04461Help
Entry
K04461                      KO                                     

Name
PPM1B, PP2CB
Definition
protein phosphatase 1B [EC:3.1.3.16]
Pathway
ko04010  MAPK signaling pathway
ko04013  MAPK signaling pathway - fly
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04461  PPM1B, PP2CB; protein phosphatase 1B
   04013 MAPK signaling pathway - fly
    K04461  PPM1B, PP2CB; protein phosphatase 1B
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatase and associated proteins
    K04461  PPM1B, PP2CB; protein phosphatase 1B
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     K04461  PPM1B, PP2CB; protein phosphatase 1B
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Mg2+- or Mn2+- dependent protein phosphatases (PPMs)
   PPM1 phosphatases (PP2C)
    K04461  PPM1B, PP2CB; protein phosphatase 1B
BRITE hierarchy
Other DBs
GO: 0004722
Genes
HSA: 5495(PPM1B)
PTR: 470365(PPM1B)
PPS: 100970133(PPM1B)
GGO: 101125633(PPM1B)
PON: 100174642(PPM1B)
NLE: 100602275(PPM1B)
MCC: 713918(PPM1B)
MCF: 101925493(PPM1B)
CSAB: 103220376(PPM1B)
RRO: 104656806(PPM1B)
RBB: 108522486(PPM1B)
CJC: 100401809(PPM1B)
SBQ: 101030095(PPM1B)
MMU: 19043(Ppm1b)
RNO: 24667(Ppm1b)
CGE: 100761807(Ppm1b)
NGI: 103725766(Ppm1b)
HGL: 101724963(Ppm1b)
CCAN: 109700490(Ppm1b)
OCU: 100356616(PPM1B)
TUP: 102470353(PPM1B)
CFA: 474573(PPM1B)
AML: 100467132(PPM1B)
UMR: 103671219(PPM1B)
ORO: 101384232(PPM1B)
FCA: 101094170(PPM1B)
PTG: 102952906(PPM1B)
AJU: 106984846(PPM1B)
BTA: 281995(PPM1B)
BOM: 102285746(PPM1B)
BIU: 109566034(PPM1B)
PHD: 102319572(PPM1B)
CHX: 102189871(PPM1B)
OAS: 101112467(PPM1B)
SSC: 100511191(PPM1B)
CFR: 102503514(PPM1B)
CDK: 105103559(PPM1B)
BACU: 103010033(PPM1B)
LVE: 103081870(PPM1B)
OOR: 101278453(PPM1B)
ECB: 100053585(PPM1B)
EPZ: 103547776(PPM1B)
EAI: 106826237(PPM1B)
MYB: 102260600(PPM1B)
MYD: 102762240(PPM1B)
HAI: 109385547(PPM1B)
RSS: 109456371(PPM1B)
PALE: 102898576(PPM1B)
LAV: 100661934(PPM1B)
TMU: 101351643
MDO: 100033369(PPM1B)
SHR: 100926097(PPM1B)
GGA: 421404(PPM1B)
MGP: 100545622(PPM1B)
CJO: 107311144(PPM1B)
APLA: 101793008(PPM1B)
ACYG: 106031474(PPM1B)
TGU: 100220992(PPM1B)
GFR: 102045045(PPM1B)
FAB: 101817651(PPM1B)
PHI: 102109473(PPM1B)
PMAJ: 107201906(PPM1B)
CCW: 104685681(PPM1B)
FPG: 101918292(PPM1B)
FCH: 102059957(PPM1B)
CLV: 102089752(PPM1B)
EGZ: 104128753(PPM1B)
AAM: 106490397(PPM1B)
ASN: 102370584(PPM1B)
AMJ: 102563048(PPM1B)
PSS: 102449938(PPM1B)
CMY: 102932180(PPM1B)
CPIC: 101948402(PPM1B)
ACS: 100552799(ppm1b)
PVT: 110082728(PPM1B)
PBI: 103051565(PPM1B)
GJA: 107119520(PPM1B)
XLA: 432133(ppm1b) 443768(ppm1b.L)
XTR: 493392(ppm1b)
NPR: 108787040(PPM1B)
DRE: 100003481(ppm1bb) 30672(ppm1ba)
IPU: 108263292(ppm1b) 108273990
AMEX: 103024377(ppm1b) 103035481
TRU: 101079734(ppm1b)
NCC: 104951029 104954884(ppm1b)
MZE: 101466509(ppm1b) 101467207
OLA: 101156612 101157967(ppm1b)
XMA: 102232357(ppm1b) 102236622
PRET: 103476408(ppm1b) 103481540
NFU: 107375843(ppm1b) 107387759
CSEM: 103381533 103387119(ppm1b)
LCF: 108882766 108897422(ppm1b)
HCQ: 109510082(ppm1b) 109530175
BPEC: 110156933(ppm1b) 110174583
ELS: 105006041 105021243(ppm1b)
SFM: 108918089(ppm1b) 108931550
LCM: 102351165(PPM1B)
CMK: 103172185 103180804(ppm1b)
SPU: 585672
APLC: 110982527
SKO: 100368602
DME: Dmel_CG1906(alph) Dmel_CG6036(CG6036)
DSI: Dsimw501_GD18139(Dsim_GD18139) Dsimw501_GD21442(Dsim_GD21442)
MDE: 101894991
AAG: 5577917
BIM: 100749110
BTER: 100645370
SOC: 105194133
AEC: 105150784
ACEP: 105618209
PBAR: 105426969
HST: 105185131
CFO: 105247762
LHU: 105668786
PGC: 109859621
NVI: 100123349
TCA: 655020
DPA: 109536249
NVL: 108566149
BMOR: 101740492
PMAC: 106707949
PRAP: 111000875
PXY: 105384843
ZNE: 110828588
TUT: 107367884
CEL: CELE_F25D1.1(ppm-1)
CBR: CBG09633(Cbr-tag-93)
BMY: Bm1_34490
TSP: Tsp_05990
CRG: 105339254
MYI: 110441625
OBI: 106873603
LAK: 106162696
SHX: MS3_05532
AQU: 100632919
MNG: MNEG_2607
SMIN: v1.2.000657.t1(symbB.v1.2.000657.t1) v1.2.000744.t1(symbB.v1.2.000744.t1)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Sun W, Yu Y, Dotti G, Shen T, Tan X, Savoldo B, Pass AK, Chu M, Zhang D, Lu X, Fu S, Lin X, Yang J
  Title
PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activation.
  Journal
Cell Signal 21:95-102 (2009)
DOI:10.1016/j.cellsig.2008.09.012
  Sequence
[hsa:5495]
Reference
  Authors
Zhao Y, Liang L, Fan Y, Sun S, An L, Shi Z, Cheng J, Jia W, Sun W, Mori-Akiyama Y, Zhang H, Fu S, Yang J
  Title
PPM1B negatively regulates antiviral response via dephosphorylating TBK1.
  Journal
Cell Signal 24:2197-204 (2012)
DOI:10.1016/j.cellsig.2012.06.017
  Sequence
[hsa:5495]
Reference
PMID:9684878
  Authors
Marley AE, Kline A, Crabtree G, Sullivan JE, Beri RK
  Title
The cloning expression and tissue distribution of human PP2Cbeta.
  Journal
FEBS Lett 431:121-4 (1998)
DOI:10.1016/S0014-5793(98)00708-X
  Sequence
[hsa:5495]

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