KEGG   ORTHOLOGY: K04464Help
Entry
K04464                      KO                                     

Name
MAPK7
Definition
mitogen-activated protein kinase 7 [EC:2.7.11.24]
Pathway
ko04010  MAPK signaling pathway
ko04011  MAPK signaling pathway - yeast
ko04138  Autophagy - yeast
ko04139  Mitophagy - yeast
ko04540  Gap junction
ko04657  IL-17 signaling pathway
ko04722  Neurotrophin signaling pathway
ko04912  GnRH signaling pathway
ko04921  Oxytocin signaling pathway
ko05206  MicroRNAs in cancer
ko05418  Fluid shear stress and atherosclerosis
Module
M00690  MAPK (ERK5) signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
   04011 MAPK signaling pathway - yeast
    K04464  MAPK7; mitogen-activated protein kinase 7
 Cellular Processes
  Transport and catabolism
   04138 Autophagy - yeast
    K04464  MAPK7; mitogen-activated protein kinase 7
   04139 Mitophagy - yeast
    K04464  MAPK7; mitogen-activated protein kinase 7
  Cellular community - eukaryotes
   04540 Gap junction
    K04464  MAPK7; mitogen-activated protein kinase 7
 Organismal Systems
  Immune system
   04657 IL-17 signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
  Endocrine system
   04912 GnRH signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
   04921 Oxytocin signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
  Nervous system
   04722 Neurotrophin signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    K04464  MAPK7; mitogen-activated protein kinase 7
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K04464  MAPK7; mitogen-activated protein kinase 7
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00690  MAPK (ERK5) signaling
     K04464  MAPK7; mitogen-activated protein kinase 7
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     K04464  MAPK7; mitogen-activated protein kinase 7
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   K04464  MAPK7; mitogen-activated protein kinase 7
BRITE hierarchy
Other DBs
COG: COG0515
GO: 0004707
Genes
HSA: 5598(MAPK7)
PTR: 454499(MAPK7)
PPS: 100967254(MAPK7)
GGO: 101137450(MAPK7)
PON: 100451029(MAPK7)
NLE: 100598787(MAPK7)
MCC: 702837(MAPK7)
MCF: 102133212(MAPK7)
CSAB: 103242509(MAPK7)
RRO: 104660707(MAPK7)
RBB: 108516767(MAPK7)
CJC: 100400023(MAPK7)
SBQ: 101050659(MAPK7)
MMU: 23939(Mapk7)
RNO: 100912585 114509(Mapk7)
CGE: 100758520(Mapk7)
NGI: 103728439(Mapk7)
HGL: 101726391(Mapk7)
CCAN: 109699716(Mapk7)
OCU: 100338535(MAPK7)
TUP: 102475335(MAPK7)
CFA: 489532(MAPK7)
AML: 100470193(MAPK7)
UMR: 103658546(MAPK7)
ORO: 101365927(MAPK7)
FCA: 101097357(MAPK7)
PTG: 102964803(MAPK7)
AJU: 106981402(MAPK7)
BTA: 537703(MAPK7)
BOM: 102278560(MAPK7)
BIU: 109574161(MAPK7)
PHD: 102335953(MAPK7)
CHX: 102180534(MAPK7)
OAS: 101110073(MAPK7)
SSC: 102164433(MAPK7)
CFR: 102524416
CDK: 105100603(MAPK7)
BACU: 102999884(MAPK7)
LVE: 103080813(MAPK7)
OOR: 101284808(MAPK7)
ECB: 100073174(MAPK7)
EPZ: 103565868(MAPK7)
EAI: 106837912(MAPK7)
MYB: 102245831(MAPK7)
MYD: 102769984(MAPK7)
HAI: 109377280(MAPK7)
RSS: 109459377(MAPK7)
PALE: 102897014(MAPK7)
LAV: 100671889(MAPK7)
TMU: 101346669
MDO: 100016316(MAPK7)
SHR: 100917749(MAPK7)
OAA: 100088657(MAPK7)
GGA: 100858386
MGP: 104916721(MAPK7)
CJO: 107307520(MAPK7)
FAB: 101806540
PHI: 102111242(MAPK7)
PMAJ: 107199450
FPG: 101912679
ASN: 102386241(MAPK7)
AMJ: 102577139(MAPK7)
PSS: 102463278(MAPK7)
CMY: 102938366
CPIC: 101932787(MAPK7)
ACS: 100553854(mapk7)
PVT: 110086378(MAPK7)
PBI: 103052089(MAPK7)
GJA: 107122186(MAPK7)
XLA: 446599(mapk7.L)
XTR: 779785(mapk7)
NPR: 108800678(MAPK7)
DRE: 541323(mapk7)
SRX: 107719547
SANH: 107654010
SGH: 107557341
IPU: 108273635(mapk7)
AMEX: 103030026(mapk7)
TRU: 101079574(mapk7)
LCO: 104935550(mapk7)
NCC: 104967446(mapk7)
MZE: 101467194(mapk7)
OLA: 101157651
XMA: 102229633(mapk7)
PRET: 103481413(mapk7)
NFU: 107387979(mapk7)
CSEM: 103382039(mapk7)
LCF: 108884456(mapk7)
HCQ: 109523949(mapk7)
BPEC: 110159641
SASA: 106586755(mapk7)
ELS: 105007802(mapk7)
SFM: 108941647(mapk7)
LCM: 102358623(MAPK7)
CIN: 778597(erk5)
SPU: 574672
APLC: 110988303
SKO: 100376580
CEL: CELE_C04G6.1(mpk-2)
CBR: CBG02327(Cbr-mpk-2)
BMY: Bm1_25835
CRG: 105318778
MYI: 110446046
OBI: 106880255
LAK: 106179980
EPA: 110250865
ADF: 107339979
AQU: 100635536
ATH: AT1G01560(MPK11) AT2G46070(MPK12) AT4G11330(MPK5)
THJ: 104817310
CIT: 102616880
GRA: 105789096
EGR: 104443843
ADU: 107479878
AIP: 107630763
PMUM: 103337562
PXB: 103953390
RCU: 8287426
JCU: 105645760
VVI: 100260441
OSA: 4349225
DOSA: Os10t0533600-01(Os10g0533600)
OBR: 102701584
SBI: 8076598
ZMA: 542144(simk1)
SITA: 101786841
EGU: 105054967
SCE: YHR030C(SLT2)
ERC: Ecym_7361
NCS: NCAS_0A06680(NCAS0A06680)
NDI: NDAI_0D01620(NDAI0D01620)
TPF: TPHA_0B02440(TPHA0B02440)
TBL: TBLA_0A10420(TBLA0A10420)
TDL: TDEL_0E03520(TDEL0E03520)
KAF: KAFR_0E01810(KAFR0E01810)
CAL: CAALFM_CR00120CA(MKC1)
CDU: CD36_25140(MKC1)
MGR: MGG_04943
BFU: BCIN_09g02390(bmp3)
ANI: AN5666.2
ANG: ANI_1_1286014(An01g09520)
SPO: SPBC119.08(pmk1)
CNE: CNI00410
CNB: CNBH0400
MGL: MGL_2731
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7646528
  Authors
Lee JD, Ulevitch RJ, Han J
  Title
Primary structure of BMK1: a new mammalian map kinase.
  Journal
Biochem Biophys Res Commun 213:715-24 (1995)
DOI:10.1006/bbrc.1995.2189
  Sequence
[hsa:5598]
Reference
  Authors
Hayashi M, Tapping RI, Chao TH, Lo JF, King CC, Yang Y, Lee JD
  Title
BMK1 mediates growth factor-induced cell proliferation through direct cellular activation of serum and glucocorticoid-inducible kinase.
  Journal
J Biol Chem 276:8631-4 (2001)
DOI:10.1074/jbc.C000838200
  Sequence
[hsa:5598]
Reference
PMID:9111331
  Authors
Watanabe Y, Takaesu G, Hagiwara M, Irie K, Matsumoto K
  Title
Characterization of a serum response factor-like protein in Saccharomyces cerevisiae, Rlm1, which has transcriptional activity regulated by the Mpk1 (Slt2) mitogen-activated protein kinase pathway.
  Journal
Mol Cell Biol 17:2615-23 (1997)
DOI:10.1128/MCB.17.5.2615
  Sequence
[sce:YHR030C]

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